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Orasure (OSUR)
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Orasure Technologies (OSUR) AI Stock Analysis

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OSUR

Orasure Technologies

(NASDAQ:OSUR)

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Neutral 46 (OpenAI - 4o)
Rating:46Neutral
Price Target:
$2.00
▼(-34.21% Downside)
Orasure Technologies' overall stock score is primarily impacted by its financial performance challenges, including negative profitability and cash flow issues. Technical analysis indicates bearish momentum, and valuation metrics reflect ongoing financial difficulties. While strategic initiatives were highlighted in the earnings call, significant revenue declines and financial losses suggest a challenging outlook.

Orasure Technologies (OSUR) vs. SPDR S&P 500 ETF (SPY)

Orasure Technologies Business Overview & Revenue Model

Company DescriptionOraSure Technologies, Inc., together with its subsidiaries, develops, manufactures, markets, and sells oral fluid diagnostic products and specimen collection devices in the United States, Europe, and internationally. It operates in two segments, Diagnostics and Molecular Solutions. The company's principal products include InteliSwab COVID-19 rapid test, InteliSwab COVID-19 rapid test pro, InteliSwab COVID-19 rapid test rx, OraQuick Rapid HIV test, OraQuick In-Home HIV test, OraQuick HIV self-test, OraQuick HCV rapid antibody test, OraQuick Ebola rapid antigen test, OraSure oral fluid collection device used in conjunction with screening and confirmatory tests for HIV-1 antibodies; Intercept drug testing systems; immunoassay tests and reagents; and Q.E.D. saliva alcohol test. It also offers genomic products under the Oragene and ORAcollect brands; microbiome collection products; and GenoFIND genomics laboratory services. In addition, the company provides ORAcollect, RNA and OMNIgene, and RAL collection devices for use in connection with COVID-19 molecular testing; offers Colli-Pee collection device for the volumetric collection of first void urine; and manufactures and sells kits that are used to collect, stabilize, transport, and store samples of genetic material for molecular testing in the academic research and commercial applications, including ancestry, disease risk management, lifestyle, and animal testing. Further, it provides other diagnostic products, such as immunoassays and other in vitro diagnostic tests. The company markets its products to clinical laboratories, hospitals, clinics, community-based organizations and other public health organizations, distributors, government agencies, physicians' offices, and commercial and industrial entities. OraSure Technologies, Inc. was incorporated in 2000 and is headquartered in Bethlehem, Pennsylvania.
How the Company Makes MoneyOraSure Technologies generates revenue primarily through the sale of its diagnostic products and testing services. Key revenue streams include sales from its OraQuick rapid HIV tests, which are used in various healthcare settings, and its testing solutions for hepatitis C. The company also earns revenue from its collection devices, which are utilized in drug testing programs. Significant partnerships with governmental health organizations, pharmaceutical companies, and healthcare providers enhance its market reach and drive sales. Additionally, OraSure's involvement in research and development grants and collaborations further contributes to its earnings, positioning it as a vital player in public health initiatives.

Orasure Technologies Earnings Call Summary

Earnings Call Date:Nov 05, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 03, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted OraSure's strategic initiatives, such as the acquisition of BioMedomics and the renewal of important public health programs. However, the call also addressed significant revenue declines in both U.S. and International Diagnostics segments and continued financial losses, indicating a challenging year ahead.
Q3-2025 Updates
Positive Updates
Strategic Transformation and Growth Plans
OraSure continues to advance its strategic transformation, focusing on product diversification and investments in R&D, acquisitions, and partnerships. The company is positioning itself for growth in 2026.
BioMedomics Acquisition
OraSure signed a definitive agreement to acquire BioMedomics, expanding its Diagnostic portfolio with Sickle SCAN, a rapid test for sickle cell disease. This acquisition is expected to leverage existing international sales channels.
Renewal of Together Take Me Home Program
The HIV self-test program, funded by the federal government, was renewed with bipartisan support, ensuring continued revenue and support for OraSure's public health initiatives.
Positive Feedback on HEMAcollect PROTEIN
Since its launch, HEMAcollect PROTEIN has received positive feedback from customers, supporting momentum in the proteomics market for 2026.
Strong Financial Position
OraSure ended Q3 with $216 million in cash and cash equivalents and zero debt, supporting its strategy of investing in growth opportunities.
Negative Updates
Revenue Decline in International Diagnostics
International Diagnostics revenue is expected to decline by approximately 20% compared to 2024 due to slower order pace and changes in national health program funding.
U.S. Diagnostics Revenue Decline
U.S. Diagnostics business is expected to see a low single-digit percentage decline in revenue for 2025 compared to 2024, impacted by staffing reductions and budgetary uncertainties in federal agencies.
Sample Management Revenue Challenges
Sample Management revenues are expected to be flat compared to 2024 due to a decline in orders from a major consumer genetics customer.
Continued Financial Losses
OraSure reported a GAAP operating loss of $16.1 million and a non-GAAP operating loss of $12.7 million for Q3.
Company Guidance
During the OraSure Technologies, Inc. 2025 Third Quarter Earnings Conference Call, key financial metrics and future guidance were highlighted. The company reported total revenue of $27.1 million, with core revenue at $27.0 million, comprising $14.5 million from Diagnostics and $10.3 million from Sample Management. The gross margin was 43.5% on a GAAP basis and 44.2% non-GAAP, with operating expenses at $27.9 million. The company expects fourth-quarter revenue of $25 to $28 million and operating expenses around $20 million, alongside $10 million in innovation investments. The International Diagnostics business is projected to decline approximately 20% compared to 2024, while U.S. Diagnostics is expected to generate revenue in the low to mid-$30 million range, slightly down from 2024. The Sample Management business is anticipated to remain flat compared to the previous year, with revenues in the high $30 million range. Additionally, OraSure announced the acquisition of BioMedomics, aiming to expand its diagnostic portfolio with the Sickle SCAN test for sickle cell disease.

Orasure Technologies Financial Statement Overview

Summary
Orasure Technologies faces significant profitability and cash flow challenges, with negative margins and declining cash flow. The balance sheet remains a relative strength due to low leverage, but the company must address its operational inefficiencies to improve financial health.
Income Statement
45
Neutral
Orasure Technologies has experienced a decline in profitability, with negative net profit and EBIT margins in the TTM period. Revenue growth is modest at 2.13% TTM, but historical revenue has been volatile. The company faces challenges in maintaining profitability, as evidenced by negative EBIT and EBITDA margins.
Balance Sheet
60
Neutral
The balance sheet shows a strong equity position with a low debt-to-equity ratio of 0.037 in the TTM period, indicating low leverage. However, the return on equity is negative, reflecting ongoing profitability challenges. The equity ratio remains stable, suggesting a solid capital structure.
Cash Flow
40
Negative
Cash flow metrics indicate significant challenges, with negative free cash flow growth and operating cash flow. The free cash flow to net income ratio is positive, suggesting some ability to convert earnings into cash, but overall cash flow performance is weak.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue125.70M185.83M405.47M387.48M233.67M171.72M
Gross Profit50.80M79.39M179.42M148.44M117.60M101.87M
EBITDA-51.50M-13.55M64.35M10.29M846.00K3.44M
Net Income-60.24M-19.50M53.66M-17.13M-23.00M-14.92M
Balance Sheet
Total Assets423.10M479.66M482.85M444.18M460.99M454.47M
Cash, Cash Equivalents and Short-Term Investments216.48M267.76M290.41M110.85M153.04M209.40M
Total Debt13.46M14.60M13.50M12.55M12.27M6.13M
Total Liabilities61.12M69.32M52.17M79.75M80.46M55.90M
Stockholders Equity361.98M410.34M430.67M364.43M380.53M398.57M
Cash Flow
Free Cash Flow-43.65M23.58M131.28M-111.11M-83.50M-23.12M
Operating Cash Flow-39.92M27.37M141.58M-47.20M-35.38M5.81M
Investing Cash Flow-7.88M-39.03M66.15M21.09M-5.50M-14.03M
Financing Cash Flow-11.94M-4.18M-3.02M-3.83M-2.82M92.48M

Orasure Technologies Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.04
Price Trends
50DMA
2.89
Negative
100DMA
3.00
Negative
200DMA
3.07
Negative
Market Momentum
MACD
-0.21
Positive
RSI
26.12
Positive
STOCH
9.96
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OSUR, the sentiment is Negative. The current price of 3.04 is above the 20-day moving average (MA) of 2.50, above the 50-day MA of 2.89, and below the 200-day MA of 3.07, indicating a bearish trend. The MACD of -0.21 indicates Positive momentum. The RSI at 26.12 is Positive, neither overbought nor oversold. The STOCH value of 9.96 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OSUR.

Orasure Technologies Risk Analysis

Orasure Technologies disclosed 67 risk factors in its most recent earnings report. Orasure Technologies reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Orasure Technologies Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
68
Neutral
$94.30M8.6330.92%23.65%120.84%
63
Neutral
$172.68M15.259.59%2.09%-12.35%-17.20%
58
Neutral
$247.71M-170.24%19.61%-3.42%
53
Neutral
$178.47M-39.27-21.71%22.12%69.19%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$157.10M-15.30%-43.95%-620.21%
41
Neutral
$170.31M-27.19%30.55%-340.19%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OSUR
Orasure Technologies
2.11
-1.77
-45.62%
PDEX
Pro-Dex
30.83
-15.92
-34.05%
STXS
Stereotaxis
2.24
0.19
9.27%
UTMD
Utah Medical Products
53.80
-10.16
-15.88%
KRMD
REPRO-MED Systems
4.40
0.88
25.00%
SMTI
Sanara MedTech
19.14
-18.56
-49.23%

Orasure Technologies Corporate Events

OraSure Earnings Call: Strategic Moves Amid Financial Challenges
Nov 7, 2025

During the recent earnings call, OraSure Technologies presented a mixed sentiment, highlighting both strategic advancements and financial challenges. The company emphasized its strategic initiatives, including the acquisition of BioMedomics and the renewal of vital public health programs. However, significant revenue declines in both U.S. and International Diagnostics segments, along with ongoing financial losses, suggest a challenging year ahead.

OraSure Technologies Reports Q3 2025 Financial Results
Nov 6, 2025

OraSure Technologies, Inc., a prominent player in the healthcare sector, specializes in point-of-need and home diagnostic tests and sample management solutions, aiming to enhance healthcare accessibility and personalization. In its third-quarter 2025 financial results, OraSure reported a total revenue of $27.1 million, reflecting a 32% decline compared to the same period in 2024. Despite the challenges, the company remains optimistic about its growth prospects in 2026, driven by product diversification and new launches. Key financial metrics revealed a 25% decrease in core business revenues and a 34% drop in diagnostics revenue, primarily due to reduced HIV test sales. The company also reported a net loss of $13.7 million for the quarter. OraSure’s strategic initiatives include the acquisition of BioMedomics, which is expected to expand its diagnostic portfolio, and continued collaboration with public health programs. Looking forward, OraSure remains focused on its innovation roadmap and is preparing for the launch of new products in 2026, positioning itself for sustainable growth.

Business Operations and StrategyFinancial DisclosuresProduct-Related Announcements
OraSure Technologies Reports Q3 2025 Financial Results
Neutral
Nov 5, 2025

OraSure Technologies announced its financial results for the third quarter of 2025, reporting $27.1 million in revenue. Despite challenges related to funding uncertainties for public health programs, the company is optimistic about returning to growth in 2026 through product diversification and new product launches. The company is focusing on decentralizing diagnostics to make healthcare more accessible and personalized, with upcoming products like the Sherlock over-the-counter molecular self-test for Chlamydia and Gonorrhoeae and the Colli-Pee urine self-collection for sexually transmitted infections.

The most recent analyst rating on (OSUR) stock is a Hold with a $2.50 price target. To see the full list of analyst forecasts on Orasure Technologies stock, see the OSUR Stock Forecast page.

Executive/Board Changes
OraSure Technologies Announces Board Leadership Changes
Neutral
Oct 28, 2025

On October 28, 2025, OraSure Technologies announced the resignation of Mara G. Aspinall from her position as director and chair of the Board, with no disputes cited as the cause. John P. Kenny, a current board member, has been appointed as the new chair. Additionally, Steven Boyd has been appointed as a Class II director, effective the same day, and will serve on the Audit Committee and the Nominating and Corporate Governance Committee. Boyd qualifies as an independent director and will receive an initial equity award valued at $100,000, which will vest in two years.

The most recent analyst rating on (OSUR) stock is a Hold with a $3.00 price target. To see the full list of analyst forecasts on Orasure Technologies stock, see the OSUR Stock Forecast page.

OraSure’s Earnings Call: Mixed Outlook with Key Achievements
Aug 7, 2025

OraSure Technologies recently held its second-quarter earnings call, presenting a mixed outlook characterized by both achievements and challenges. While the company reported notable progress in revenue and innovation, it also faced significant hurdles in segments such as Sample Management and international diagnostics, primarily due to external factors. Despite advancements in strategic initiatives, immediate financial impacts remain a concern for the company.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 19, 2025