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Organogenesis Holdings Inc (ORGO)
NASDAQ:ORGO

Organogenesis Holdings Inc (ORGO) AI Stock Analysis

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Organogenesis Holdings Inc

(NASDAQ:ORGO)

Rating:43Neutral
Price Target:
$3.50
▲(0.86%Upside)
Organogenesis Holdings faces considerable financial and technical challenges, with declining revenue, profitability, and cash flow impacting the stock's attractiveness. Technical analysis also indicates bearish sentiment, while valuation metrics are unfavorable due to negative earnings. Despite strategic advancements and cash reserves, immediate financial issues weigh heavily on the stock's overall score.
Positive Factors
Debt Reduction
The recent debt reduction by Organogenesis Holdings has contributed to a higher price target, reflecting improved financial stability.
Market Consolidation
Organogenesis is expected to benefit from market consolidation, which could lead to growth as business dynamics normalize.
Sales Performance
Revenue in the fourth quarter exceeded expectations with a strong sales performance, indicating robust demand for Organogenesis's products.
Negative Factors
LCD Uncertainty
ORGO's 1Q25 results were negatively impacted by continued LCD uncertainty regarding skin substitute grafts, where implementation has been delayed a third time to January 1, 2026.
Sales Guidance
Management's revised sales guidance implies a significant back-end weighted ramp, which in our view adds a degree of risk in hitting full year targets.
Sales Risks
Despite good performance, LCDs and sales risks remain an overhang on shares, potentially limiting stock value growth.

Organogenesis Holdings Inc (ORGO) vs. SPDR S&P 500 ETF (SPY)

Organogenesis Holdings Inc Business Overview & Revenue Model

Company DescriptionOrganogenesis Holdings Inc., a regenerative medicine company develops, manufactures, and commercializes solutions for the advanced wound care, and surgical and sports medicine markets in the United States. The company's advanced wound care products include Affinity, an amniotic membrane wound covering in which viable cells growth factors/cytokines, and ECM proteins in the native tissue are preserved; Apligraf, a bioengineered living cell therapy that produce spectrum of cytokines and growth factors; Dermagraft, a bioengineered product that produces human collagen, ECM, proteins, and cytokines; NuShield, a wound covering tissue includes both amnion and chorion membranes for spongy/intermediate layer intact; PuraPly , a antimicrobial barrier that enables conformability and fluid drainage; and Novachor, an amniotic membrane wound covering in which viable cells, growth factors/cytokines, and ECM proteins are preserved. Its surgical and sports medicine products comprise NuCel, a dehydrated placental tissue surgically applied to the target tissue to support native healing; ReNu, a cryopreserved suspension used to support healing of soft tissues; and FiberOS and OCMP used as a bone void filler primarily in orthopedic and neurosurgical applications. The company's pipeline products include PuraPly XT and PuraPly MZ to treat chronic, acute, and open wounds; PuraForce, a bioengineered porcine collagen surgical matrix for use in soft tissue reinforcement applications; and TransCyte, a bioengineered tissue for the treatment of partial thickness burns. It serves hospitals, wound care centers, government facilities, ambulatory service centers, and physician office through direct sales force and independent agencies. The company was founded in 1985 and is headquartered in Canton, Massachusetts.
How the Company Makes MoneyOrganogenesis Holdings Inc. generates revenue primarily through the sale of its advanced wound care and surgical biologics products. The company's revenue streams are largely driven by the commercialization of its proprietary technologies, which include bioactive wound healing and tissue repair solutions. Organogenesis partners with healthcare providers, hospitals, and clinics to provide these products for patient care, establishing contracts and agreements that facilitate widespread distribution. Additionally, the company invests in research and development to expand its product offerings and enhance its competitive position in the regenerative medicine market. Significant factors contributing to its earnings include a growing demand for effective wound care solutions and strategic partnerships that enhance product reach and adoption.

Organogenesis Holdings Inc Earnings Call Summary

Earnings Call Date:May 08, 2025
(Q1-2025)
|
% Change Since: -35.02%|
Next Earnings Date:Aug 06, 2025
Earnings Call Sentiment Neutral
The earnings call reflects a challenging quarter for Organogenesis, marked by significant revenue declines and increased losses due to disruptions from LCD implementation delays. However, the reaffirmed revenue guidance, growth in Surgical and Sports Medicine, and strategic advancements in product development and manufacturing highlight potential for future recovery and growth.
Q1-2025 Updates
Positive Updates
Surgical and Sports Medicine Revenue Growth
Net revenue from Surgical and Sports Medicine products for the first quarter was $6.8 million, up 11% year-over-year.
Strong Financial Position
The company had $110.5 million in cash, cash equivalents, and restricted cash with no outstanding debt obligations as of 03/31/2025.
Reaffirmed 2025 Revenue Guidance
The company reaffirmed its net revenue guidance for 2025 of between $480 million and $535 million, representing a year-over-year change in the range of roughly flat to an increase of 11%.
Development and Submission Progress
Organogenesis is on track to submit additional clinical and real-world evidence to CMS and plans to submit a BLA for RENEW by the end of the year.
Expansion of Manufacturing Capabilities
Significant progress in expanding manufacturing capabilities with a new facility in Smithfield, Rhode Island, to support new product introductions and reintroductions.
Negative Updates
Significant Revenue Decline
Net revenue for the first quarter was $86.7 million, down 21% year-over-year.
Advanced Wound Care Revenue Decline
Advanced Wound Care net revenue for the first quarter was $79.9 million, down 23% year-over-year.
Increased Operating Loss
Operating loss for the first quarter was $26.7 million compared to an operating loss of $3.9 million last year, an increase of $22.9 million.
Net Loss Increase
GAAP net loss for the first quarter was $18.8 million compared to a net loss of $2.1 million last year, an increase of $16.7 million.
Challenges Due to LCD Implementation Delays
Delays in LCD implementation led to uncertainty and disruption in customer demand and ordering patterns, impacting revenue and gross profit.
Company Guidance
During the first quarter 2025 earnings call, Organogenesis Holdings Inc. reaffirmed their financial guidance for the year, projecting net revenue between $480 million and $535 million, with anticipated growth ranging from flat to an 11% increase year-over-year. The company reported a Q1 net revenue of $86.7 million, reflecting a 21% decline, aligning with their prior guidance of $85 to $95 million. Advanced Wound Care products contributed $79.9 million, a 23% decrease, while Surgical and Sports Medicine products reported an 11% increase, totaling $6.8 million. The gross margin for the quarter was 72.6%, slightly down from last year's 73.9%, impacted by lower revenue and product expiration due to a delayed LCD implementation. Operating expenses increased by 5% to $89.7 million, influenced by a $6.6 million asset write-down, partially offset by a 17% reduction in R&D expenses. The call highlighted the company's strategic focus on leveraging its diverse product portfolio and customer relationships to navigate market challenges, particularly in light of CMS's delay in LCD implementation to 2026, which Organogenesis supports as an opportunity to review coverage policies and submit additional evidence for product coverage.

Organogenesis Holdings Inc Financial Statement Overview

Summary
Organogenesis Holdings exhibits a mix of strengths and weaknesses across its financial statements. While gross profitability and asset management are positive, inconsistent revenue and cash flow performance pose concerns. The balance sheet's moderate leverage and stable equity base provide some reassurance, but operational efficiency needs improvement to enhance profitability.
Income Statement
55
Neutral
Organogenesis Holdings has demonstrated a volatile revenue trajectory with fluctuations over the years. The gross profit margin remains healthy, indicating efficient production processes, but net profit margins have been inconsistent, turning negative recently. The company has struggled to maintain stable EBIT and EBITDA margins, particularly in the latest period, which reflects operational challenges.
Balance Sheet
60
Neutral
The company's balance sheet shows moderate leverage with a debt-to-equity ratio that suggests manageable debt levels. The return on equity has been positive but decreased over time, indicating declining profitability for shareholders. The equity ratio reflects a solid asset base supported by equity, offering some financial stability.
Cash Flow
50
Neutral
Free cash flow has been inconsistent, with a recent decrease reflecting higher capital expenditures relative to operating cash flows. The operating cash flow to net income ratio suggests that cash generation from operations is stable, but free cash flow conversion remains a challenge.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
482.04M433.14M450.89M468.06M338.30M
Gross Profit
366.30M326.66M345.87M353.86M250.98M
EBIT
-1.28M12.53M22.30M72.92M27.41M
EBITDA
-1.28M36.03M40.32M87.00M37.23M
Net Income Common Stockholders
861.00K4.95M15.53M94.20M17.23M
Balance SheetCash, Cash Equivalents and Short-Term Investments
135.57M104.34M102.48M113.93M84.39M
Total Assets
497.89M460.02M449.36M443.26M294.49M
Total Debt
43.31M119.35M123.79M132.30M84.77M
Net Debt
-92.26M15.51M21.31M18.37M377.00K
Total Liabilities
112.57M181.36M183.69M201.22M148.41M
Stockholders Equity
262.90M278.66M265.67M242.03M146.08M
Cash FlowFree Cash Flow
4.18M6.55M-9.04M30.76M-14.34M
Operating Cash Flow
14.21M30.92M24.86M61.98M6.80M
Investing Cash Flow
-10.03M-24.36M-33.90M-31.22M-24.83M
Financing Cash Flow
27.64M-5.50M-2.20M-1.04M42.47M

Organogenesis Holdings Inc Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price3.47
Price Trends
50DMA
3.84
Negative
100DMA
4.02
Negative
200DMA
3.60
Negative
Market Momentum
MACD
-0.23
Negative
RSI
52.95
Neutral
STOCH
77.63
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ORGO, the sentiment is Neutral. The current price of 3.47 is above the 20-day moving average (MA) of 3.01, below the 50-day MA of 3.84, and below the 200-day MA of 3.60, indicating a neutral trend. The MACD of -0.23 indicates Negative momentum. The RSI at 52.95 is Neutral, neither overbought nor oversold. The STOCH value of 77.63 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for ORGO.

Organogenesis Holdings Inc Risk Analysis

Organogenesis Holdings Inc disclosed 73 risk factors in its most recent earnings report. Organogenesis Holdings Inc reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Organogenesis Holdings Inc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
$970.69M25.0919.23%17.17%-51.97%
67
Neutral
$976.05M30.8111.86%1.98%19.12%141.45%
66
Neutral
$940.30M-34.65%252.64%85.10%
60
Neutral
$1.09B-37.23%53.49%33.18%
54
Neutral
$5.37B3.35-45.10%2.79%16.77%-0.01%
43
Neutral
$384.37M928.57-4.92%5.35%-432.51%
43
Neutral
$647.33M-949.46%25.38%15.00%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ORGO
Organogenesis Holdings Inc
3.47
0.83
31.44%
AVDL
Avadel Pharmaceuticals
10.23
-4.99
-32.79%
PAHC
Phibro Animal Health
24.34
6.93
39.80%
COLL
Collegium Pharmaceutical
30.37
-1.51
-4.74%
HROW
Harrow Health
31.17
12.92
70.79%
EOLS
Evolus
9.87
-1.66
-14.40%

Organogenesis Holdings Inc Corporate Events

Business Operations and Strategy
Organogenesis Highlights Strategic Focus in Investor Presentation
Neutral
Mar 27, 2025

On March 27, 2025, Organogenesis Holdings Inc. released an investor presentation highlighting its strategic focus on addressing large unmet patient needs in chronic and acute wounds and osteoarthritis. The presentation outlines the company’s market opportunities and technological advancements, emphasizing its commitment to leading innovation in regenerative therapies. The company faces challenges such as competition and regulatory changes, but it continues to focus on enhancing its product offerings to maintain its competitive edge.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.