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Oculis Holding (OCS)
NASDAQ:OCS
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Oculis Holding (OCS) AI Stock Analysis

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OCS

Oculis Holding

(NASDAQ:OCS)

Rating:41Neutral
Price Target:
$17.00
▼(-1.85% Downside)
Oculis Holding's overall stock score is primarily impacted by its poor financial performance, with significant operational losses and declining equity. Technical analysis indicates a bearish trend, and the valuation is challenging due to negative earnings. The absence of earnings call insights and corporate events leaves the financial and technical factors as the primary drivers of the score.
Positive Factors
Clinical Trials
Enrollment for the pivotal phase 3 trials of OCS-01 in DME is complete, keeping the program on track for a key topline data readout.
Financial Stability
With cash runway extended into early 2028, Oculis is well-funded through key data catalysts.
Product Development
OCS-01 aims to be the first non-invasive therapy for DME, potentially expanding the market to patients who typically go untreated.
Negative Factors
Market Competition
There are high unmet needs in treatment for conditions Privosegtor targets, with no approved therapies available.
Regulatory Challenges
Management has made a strategic decision to submit the New Drug Application for OCS-01 for the treatment of inflammation and pain following ocular surgery after the NDA submission for diabetic macular edema.

Oculis Holding (OCS) vs. SPDR S&P 500 ETF (SPY)

Oculis Holding Business Overview & Revenue Model

Company DescriptionOculis Holding (OCS) is a biopharmaceutical company focused on the development of innovative treatments for eye diseases. The company operates primarily in the ophthalmology sector, specializing in drug delivery systems and therapies aimed at addressing a range of ocular conditions. Oculis is committed to advancing its proprietary technologies to improve patient outcomes and enhance the quality of life for individuals suffering from vision impairments.
How the Company Makes MoneyOculis generates revenue through the development and commercialization of its ophthalmic products. The primary revenue streams include sales of its proprietary drug formulations, licensing agreements with pharmaceutical companies, and collaborations with research institutions and healthcare providers. Oculis may also engage in partnerships that involve joint development of new therapies, which can result in milestone payments and royalties based on sales performance. Additionally, the company may receive funding through grants or investments aimed at supporting its research and development initiatives.

Oculis Holding Financial Statement Overview

Summary
Oculis Holding faces substantial financial challenges, particularly in profitability and revenue growth, with negative margins across the board. While the company maintains a low debt-to-equity ratio, its equity has been declining. Cash flows are under pressure, with negative free cash flow and limited conversion of losses into operational cash flow. Strategic adjustments are necessary to improve financial health.
Income Statement
20
Very Negative
Oculis Holding's TTM (Trailing-Twelve-Months) income statement shows a gross profit margin of -5747.54% and a net profit margin of -18363.60%, indicating significant operational losses. The revenue growth rate is negative, showing a decrease of 47.11% from the previous year, and both EBIT and EBITDA margins are negative, further emphasizing ongoing financial struggles.
Balance Sheet
30
Negative
The balance sheet reveals a debt-to-equity ratio of 0.02, indicating low leverage, but stockholders' equity has decreased significantly over recent years. The equity ratio is 60.96%, showing a strong equity position relative to total assets, yet the company has faced equity erosion over time.
Cash Flow
25
Negative
Cash flow analysis shows a negative free cash flow growth rate of -11.43%. The operating cash flow to net income ratio is 0.55, reflecting operational inefficiencies. The free cash flow to net income ratio is 0.56, suggesting limited cash flow generation relative to net losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue245.00K686.00K883.00K912.00K960.00K993.00K
Gross Profit-16.22M-51.40M-28.36M-21.31M-8.61M-8.34M
EBITDA-102.88M-72.80M-45.73M-31.95M-12.98M-12.10M
Net Income-102.90M-85.78M-88.80M-38.70M-18.55M-14.87M
Balance Sheet
Total Assets204.17M120.35M114.35M37.06M58.04M16.38M
Cash, Cash Equivalents and Short-Term Investments181.93M98.66M91.65M19.79M46.28M4.95M
Total Debt1.10M1.18M605.00K123.08M114.27M54.81M
Total Liabilities41.55M46.97M20.63M135.05M119.00M60.04M
Stockholders Equity162.63M73.38M93.73M-97.99M-60.95M-43.65M
Cash Flow
Free Cash Flow-54.60M-47.73M-53.89M-28.62M-13.85M-12.05M
Operating Cash Flow-53.27M-47.50M-53.84M-25.07M-13.82M-12.03M
Investing Cash Flow-67.02M-17.56M-54.21M-3.55M-28.00K-19.00K
Financing Cash Flow157.68M54.03M129.67M1.71M55.19M4.86M

Oculis Holding Technical Analysis

Technical Analysis Sentiment
Negative
Last Price17.32
Price Trends
50DMA
18.29
Negative
100DMA
18.23
Negative
200DMA
18.50
Negative
Market Momentum
MACD
-0.16
Positive
RSI
37.63
Neutral
STOCH
18.41
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OCS, the sentiment is Negative. The current price of 17.32 is below the 20-day moving average (MA) of 17.87, below the 50-day MA of 18.29, and below the 200-day MA of 18.50, indicating a bearish trend. The MACD of -0.16 indicates Positive momentum. The RSI at 37.63 is Neutral, neither overbought nor oversold. The STOCH value of 18.41 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OCS.

Oculis Holding Risk Analysis

Oculis Holding disclosed 98 risk factors in its most recent earnings report. Oculis Holding reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Oculis Holding Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
62
Neutral
$818.57M-43.63%-13.05%
56
Neutral
$2.14B-63.41%-7.26%-15.33%
55
Neutral
$829.89M-73.95%2.99%-49.11%
53
Neutral
$1.00B-63.21%-32.33%
51
Neutral
$7.83B-0.18-40.10%2.29%21.46%-2.03%
48
Neutral
$656.94M-32.71%
41
Neutral
$955.98M-85.39%-43.02%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OCS
Oculis Holding
17.32
5.27
43.73%
EYPT
EyePoint Pharmaceuticals
11.84
3.12
35.78%
OCUL
Ocular Therapeutix
12.32
3.76
43.93%
AVXL
Anavex Life Sciences
9.45
3.48
58.29%
MLYS
Mineralys Therapeutics, Inc.
15.21
2.64
21.00%
BCAX
Bicara Therapeutics Inc.
12.02
-13.39
-52.70%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 26, 2025