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Milestone Scientific (MLSS)
:MLSS
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Milestone Scientific (MLSS) AI Stock Analysis

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MLSS

Milestone Scientific

(MLSS)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
$0.50
▲(61.29% Upside)
Milestone Scientific's overall stock score is primarily impacted by its weak financial performance and bearish technical indicators. While the earnings call provided some positive sentiment due to strategic initiatives, the company's ongoing financial challenges and negative valuation metrics weigh heavily on the score.
Positive Factors
Cost Management
Effective cost management and operational restructuring can enhance profitability and provide a more sustainable financial position over time.
Expansion in Dental Segment
Expansion in the dental segment, especially internationally, diversifies revenue streams and strengthens market presence, supporting long-term growth.
Medicare Payment Rate Assignments
Securing Medicare payment rates enhances the product's marketability and can drive adoption in the medical segment, boosting future revenues.
Negative Factors
Negative Cash Flow
Persistent negative cash flow indicates operational inefficiencies and can limit the company's ability to invest in growth opportunities.
Decline in Domestic Dental Revenue
A decline in domestic dental revenue suggests potential market saturation or competitive pressures, impacting overall revenue stability.
Negative Return on Equity
A negative return on equity indicates that the company is not efficiently using shareholder investments to generate profits, affecting investor confidence.

Milestone Scientific (MLSS) vs. SPDR S&P 500 ETF (SPY)

Milestone Scientific Business Overview & Revenue Model

Company DescriptionMilestone Scientific Inc. designs, develops, and commercializes diagnostic and therapeutic injection technologies, and devices for medical, dental, and cosmetic use in the United States, China, and internationally. The company operates in two segments, Dental and Medical. Its products include CompuDent and STA Single Tooth Anesthesia System that are used for all dental procedures that require local anesthetic. The company also offers CompuFlo, a computer-controlled drug delivery system for the painless delivery of drugs, anesthetics, and other medicaments, as well as for the aspiration of bodily fluids or previously injected substances; and disposable injection handpiece for the tactile control during the injection. In addition, it provides CompuFlo Epidural, a computer controlled anesthesia system for use in various medical applications. Further, the company offers CompuMed for use in various medical procedures performed in plastic, hair restoration, and colorectal surgery, as well as podiatry, dermatology, orthopedics, and various other disciplines. Milestone Scientific Inc. was incorporated in 1989 and is headquartered in Livingston, New Jersey.
How the Company Makes MoneyMilestone Scientific generates revenue primarily through the sale of its proprietary injection technology systems and disposable products. Key revenue streams include direct sales of the CompuFlo® and Wand® systems to dental and medical practitioners, as well as recurring revenue from disposable cartridges and accessories required for these systems. Additionally, the company may engage in strategic partnerships with healthcare providers and distributors to expand its market reach. Factors contributing to its earnings include the growing demand for pain management solutions in medical and dental procedures, as well as potential licensing agreements for its technology.

Milestone Scientific Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 27, 2026
Earnings Call Sentiment Positive
The earnings call reflected a positive sentiment due to successful cost management and strategic initiatives in the Dental segment, alongside progress in securing Medicare payment rates for CompuFlo. However, challenges remain in achieving domestic revenue growth and executing a broader commercial rollout of CompuFlo.
Q3-2025 Updates
Positive Updates
Cost Reduction and Operational Restructuring
Reduced operating expenses by over $0.5 million compared to the same period last year, while maintaining stable revenue performance. These results reflect the early benefits of the company's transformational strategy.
Expansion in Dental Segment
Expanded direct sales programs in North America and advanced international registrations for the STA Single Tooth Anesthesia System. International dental sales increased year-over-year, partially offsetting the decline in domestic revenue.
Medicare Payment Rate Assignments for CompuFlo
CompuFlo system secured Medicare payment rate assignments under CPT Code 0777T in 3 jurisdictions, supported by 2 MACs, Novitas and First Coast, including states like New Jersey, Texas, and Florida.
Stable Revenue and Positive Outlook
For the 3 months and 9 months ended September 30, 2025, revenue was $2.4 million and $6.9 million, respectively, compared to $2.5 million and $6.6 million for the same period in 2024. Gross profit remained stable.
Negative Updates
Decline in Domestic Dental Revenue
Despite the increase in international dental sales, there was a decline in domestic revenue, highlighting challenges in the home market.
Challenges in Broader Commercial Rollout
The company is cautious about a broader commercialization of CompuFlo, indicating that a more extensive rollout may take additional time and focus.
Supply Chain and Tariff Concerns
Although tariffs are not currently impacting significantly, there is a need to consider a bonded warehouse in the U.S. if tariffs continue to persist.
Company Guidance
During the Milestone Scientific Third Quarter 2025 Financial Results and Business Update Call, the company provided several key metrics and guidance on their progress and future strategy. For the third quarter ending September 30, 2025, Milestone Scientific reported revenue of $2.4 million, slightly down from $2.5 million in the same period of 2024, while the revenue for the first nine months of 2025 was $6.9 million, showing an increase from $6.6 million in the previous year. The company successfully reduced operating expenses by over $0.5 million compared to the same period last year, highlighting their focus on cost management and operational restructuring. Gross profit remained stable at approximately $4.9 million for the first nine months of both 2025 and 2024. The company emphasized its transformational strategy centered around streamlining operations, enhancing commercial execution, and advancing its reimbursement and payer strategy, particularly for the CompuFlo system in the medical segment. Additionally, the organization reported having $1.3 million in cash and cash equivalents and a working capital of approximately $3.1 million as of September 30, 2025.

Milestone Scientific Financial Statement Overview

Summary
Milestone Scientific faces significant financial challenges. Despite a strong gross profit margin, the company operates at a loss with negative net profit and cash flow margins. The balance sheet shows low leverage but a concerning negative return on equity. Overall, financial health is weak, necessitating operational improvements.
Income Statement
35
Negative
Milestone Scientific's income statement reveals a challenging financial position. The company has experienced a slight revenue growth of 5.45% in the TTM period, but it continues to operate at a loss with a negative net profit margin of -61.16%. The gross profit margin is relatively strong at 74.37%, indicating efficient cost management in production. However, the negative EBIT and EBITDA margins highlight ongoing operational inefficiencies and high operating expenses.
Balance Sheet
40
Negative
The balance sheet shows a low debt-to-equity ratio of 0.07, suggesting a conservative approach to leveraging. However, the return on equity is negative at -82.73%, indicating that the company is not generating sufficient returns on shareholders' investments. The equity ratio stands at 41.48%, reflecting a moderate level of financial stability, but the overall negative ROE is a significant concern.
Cash Flow
30
Negative
Cash flow analysis indicates significant challenges, with a negative operating cash flow and free cash flow. The free cash flow growth rate is positive at 93.82%, but this is from a negative base, indicating volatility. The operating cash flow to net income ratio is negative, suggesting that the company struggles to convert its accounting profits into cash. The free cash flow to net income ratio is slightly above 1, indicating that free cash flow is in line with net income, albeit both are negative.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue9.08M8.63M9.83M8.81M10.30M5.44M
Gross Profit6.61M6.43M6.79M4.90M6.31M3.62M
EBITDA-6.86M-6.72M-7.04M-8.76M-7.30M-7.36M
Net Income-6.97M-4.71M-6.93M-8.71M-6.82M-7.34M
Balance Sheet
Total Assets8.05M9.80M11.37M13.70M19.81M19.57M
Cash, Cash Equivalents and Short-Term Investments1.27M3.26M5.95M8.72M14.76M14.22M
Total Debt1.09M349.05K395.98K497.04K586.59K942.60K
Total Liabilities4.71M3.96M3.36M3.70M3.59M3.46M
Stockholders Equity3.34M5.83M8.01M10.23M16.37M16.20M
Cash Flow
Free Cash Flow-5.26M-2.93M-5.33M-6.04M-4.03M-7.01M
Operating Cash Flow-5.26M-2.92M-5.33M-6.03M-4.02M-6.98M
Investing Cash Flow-2.98M2.97M-2.97M-8.53K-15.19K-21.44K
Financing Cash Flow789.19K233.77K2.56M-8.54K4.57M19.71M

Milestone Scientific Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.31
Price Trends
50DMA
0.42
Negative
100DMA
0.51
Negative
200DMA
0.72
Negative
Market Momentum
MACD
-0.04
Positive
RSI
34.93
Neutral
STOCH
28.09
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MLSS, the sentiment is Negative. The current price of 0.31 is below the 20-day moving average (MA) of 0.35, below the 50-day MA of 0.42, and below the 200-day MA of 0.72, indicating a bearish trend. The MACD of -0.04 indicates Positive momentum. The RSI at 34.93 is Neutral, neither overbought nor oversold. The STOCH value of 28.09 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for MLSS.

Milestone Scientific Risk Analysis

Milestone Scientific disclosed 34 risk factors in its most recent earnings report. Milestone Scientific reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Milestone Scientific Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
69
Neutral
$55.12M41.6316.29%32.36%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$36.18M-5.52-57.98%13.67%-37.01%
48
Neutral
$53.80M-376.23%63.53%12.49%
48
Neutral
$25.18M-2.81-8.05%-0.95%58.17%
41
Neutral
$29.73M-4.35-136.47%0.59%-39.76%
41
Neutral
$23.44M-5.47-58.34%73.38%34.87%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MLSS
Milestone Scientific
0.31
-0.63
-67.02%
RVP
Retractable Technologies
0.83
0.20
31.75%
POCI
Precision Optics Corporation
4.69
-0.23
-4.67%
NEPH
Nephros
4.88
3.27
203.11%
FEMY
Femasys
1.01
-0.09
-8.18%
NXGL
NexGel Inc
1.80
-1.61
-47.21%

Milestone Scientific Corporate Events

Milestone Scientific Inc. Reports Q3 2025 Financial Results
Nov 15, 2025

Milestone Scientific Inc., a Delaware-based company, specializes in the development and commercialization of computer-controlled anesthetic delivery devices for dental and medical applications. The company operates primarily in the medical technology sector, with products like the CompuDent® and CompuFlo® systems that are marketed globally.

Executive/Board Changes
Milestone Scientific Director Leonard Osser Resigns
Neutral
Nov 13, 2025

On November 7, 2025, Leonard A. Osser resigned as a director of Milestone Scientific Inc., but will continue his involvement through an employment and consulting agreement. This change in leadership may impact the company’s operations and stakeholder relations, as Mr. Osser remains connected to the company in a different capacity.

The most recent analyst rating on (MLSS) stock is a Sell with a $0.50 price target. To see the full list of analyst forecasts on Milestone Scientific stock, see the MLSS Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
Milestone Scientific Faces NYSE Non-Compliance Notice
Negative
Oct 14, 2025

On October 8, 2025, Milestone Scientific Inc. received a notice from NYSE American LLC indicating non-compliance with certain listing standards. The company must submit a compliance plan by November 7, 2025, to maintain its listing, with potential delisting if standards are not met by April 8, 2027.

The most recent analyst rating on (MLSS) stock is a Buy with a $1.25 price target. To see the full list of analyst forecasts on Milestone Scientific stock, see the MLSS Stock Forecast page.

Milestone Scientific Reports Increased Sales but Faces Losses
Aug 16, 2025

Milestone Scientific Inc., a Delaware-based company, specializes in developing computer-controlled anesthetic delivery devices for dental and medical applications, with a focus on innovative technology in the healthcare sector. In its latest earnings report for the quarter ended June 30, 2025, Milestone Scientific Inc. highlighted a net loss of $1.48 million, compared to a net income of $223,638 in the same quarter of the previous year. The company reported product sales of $2.32 million, a notable increase from $1.85 million in the same period last year, driven by a rise in dental segment sales. Despite an increase in gross profit to $1.62 million, the company faced higher operating expenses, which contributed to the overall loss. Milestone Scientific’s financial performance was impacted by increased selling, general, and administrative expenses, as well as research and development costs. The company continues to face challenges related to its cash flow and liquidity, with cash and cash equivalents decreasing to $1.27 million from $3.26 million at the end of 2024. Looking ahead, Milestone Scientific’s management remains focused on securing additional funding to support its operations and aims to enhance revenue generation from its dental and medical device segments, while also working to reduce operating expenses.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 15, 2025