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MDxHealth (MDXH)
NASDAQ:MDXH
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MDxHealth (MDXH) AI Stock Analysis

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MDXH

MDxHealth

(NASDAQ:MDXH)

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Neutral 44 (OpenAI - 4o)
Rating:44Neutral
Price Target:
$3.00
▼(-32.58% Downside)
MDxHealth's overall stock score is primarily impacted by its financial performance and valuation challenges. Despite positive developments in revenue growth and strategic acquisitions, the company's financial instability and poor valuation metrics weigh heavily on its score. The earnings call provided some optimism with operational improvements, but significant risks remain.
Positive Factors
Revenue Growth
Consistent revenue growth indicates strong market demand and effective sales strategies, enhancing long-term business sustainability.
Successful Acquisition
The acquisition of ExoDx strengthens MDxHealth’s market position and enhances cross-selling opportunities, supporting strategic growth.
Gross Margin Improvement
Improved gross margins reflect operational efficiencies and effective cost management, contributing to better profitability prospects.
Negative Factors
Financial Leverage
High leverage and negative equity indicate financial instability, posing risks to long-term solvency and financial health.
Cash Flow Challenges
Negative cash flows highlight liquidity issues, potentially limiting the company's ability to fund operations and growth initiatives.
Profitability Challenges
Ongoing profitability issues could hinder the company's ability to reinvest in growth and maintain competitive positioning.

MDxHealth (MDXH) vs. SPDR S&P 500 ETF (SPY)

MDxHealth Business Overview & Revenue Model

Company DescriptionMDxHealth (MDXH) is a global leader in molecular diagnostics, specializing in innovative tests that provide information to help personalize cancer treatment. The company operates primarily in the healthcare sector, focusing on urological cancers, particularly prostate cancer. Its core products include the ConfirmMDx test, which helps clinicians determine the presence of cancer in patients with a history of negative biopsies, and the SelectMDx test, which aids in the identification of patients at risk for aggressive prostate cancer.
How the Company Makes MoneyMDxHealth generates revenue primarily through the sale of its diagnostic tests to healthcare providers, hospitals, and laboratories. The company operates on a fee-for-service model, where it charges for each test performed. Additionally, MDxHealth may enter into partnerships with pharmaceutical companies for the development of companion diagnostics, which can create additional revenue streams. The company also benefits from reimbursement from insurance providers for its testing services, enhancing its financial stability. Key partnerships and collaborations in the healthcare space further bolster its market presence and revenue potential.

MDxHealth Earnings Call Summary

Earnings Call Date:Nov 12, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 04, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted robust revenue and volume growth, improved gross margins, and a successful acquisition of ExoDx. However, these positives were tempered by the discontinuation of the germline offering and ongoing net and operating losses. Overall, the sentiment reflects a company making strategic adjustments for future growth while managing current financial challenges.
Q3-2025 Updates
Positive Updates
Strong Revenue Growth
Q3 revenue reached $27.4 million, representing an 18% increase over the previous year, despite the strategic decision to forego the germline offering.
Positive Adjusted EBITDA
Q3 marked the second consecutive quarter of positive adjusted EBITDA at $1 million, following the first profitable quarter in Q2.
Significant Volume Growth
Total billable volume grew by 37% compared to the prior year, with liquid-based tests increasing by 65% and tissue-based tests by 18%.
Gross Margin Improvement
Gross margins improved to 65.2% from 61.2% in Q3 2024, driven by test mix and operational efficiencies.
Successful ExoDx Acquisition
The company successfully closed the ExoDx acquisition, expanding the sales organization and enhancing cross-selling opportunities.
Negative Updates
Discontinued Germline Offering
The company decided to set aside its entry into the germline market, which was expected to contribute significantly to 2025 revenue.
Operating Loss
Despite improvements, the company reported an operating loss of $2.6 million, though this was a 57% reduction compared to the previous year.
Net Loss
The net loss for the quarter was $8 million, a reduction from $11.2 million in the prior year, but still a notable negative figure.
Company Guidance
During the third quarter of 2025, MDxHealth reported significant progress in several key areas, demonstrating strong operational performance and strategic growth. The company achieved an 18% increase in revenue, reaching $27.4 million compared to the prior year's $23.3 million, driven in part by a 37% increase in total billable volume, with tissue-based tests growing by 18% and liquid-based tests by 65%. The gross profit improved by 25% to $17.9 million, resulting in a gross margin of 65.2%, up from 61.2% the previous year. The company's operating loss reduced by 57% to $2.6 million, and the net loss decreased by 28% to $8 million. Notably, adjusted EBITDA turned positive at $1 million, compared to a negative $3.8 million in 2024. Cash and cash equivalents stood at $32 million by the end of the quarter. The integration of the Exosome Diagnostics (ExoDx) acquisition is a priority, with a strategic sales force expansion from 50 to 60 reps across eight regions to optimize cross-selling opportunities. The company also decided to set aside its germline offering, originally anticipated to contribute significantly to the 2025 revenue guidance of $108-$110 million, to focus on integrating and leveraging the ExoDx acquisition.

MDxHealth Financial Statement Overview

Summary
MDxHealth shows revenue growth and a strong gross profit margin, but faces significant profitability and leverage challenges. The negative equity position and high debt levels raise concerns about financial stability. Cash flow issues further compound the company's financial difficulties, highlighting the need for strategic improvements to enhance profitability and reduce financial risk.
Income Statement
45
Neutral
MDxHealth shows a consistent revenue growth trend, with a TTM growth rate of 4.16%. However, profitability remains a challenge, as evidenced by negative net profit margins and EBIT margins. The gross profit margin is relatively strong at 63.53% TTM, indicating efficient cost management. Despite revenue growth, the company struggles to convert sales into profits, impacting overall financial health.
Balance Sheet
30
Negative
The balance sheet reveals significant financial leverage, with a negative equity position in the TTM period, leading to a concerning debt-to-equity ratio. The negative return on equity highlights ongoing profitability challenges. The equity ratio is also negative, indicating potential solvency issues. These factors suggest financial instability and high risk.
Cash Flow
40
Negative
Cash flow analysis shows a negative operating cash flow and free cash flow, with a significant decline in free cash flow growth in the TTM period. The free cash flow to net income ratio is positive, suggesting some ability to cover net losses with cash flow, but overall cash flow remains weak, indicating liquidity challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue103.07M90.05M70.19M37.05M22.24M18.46M
Gross Profit66.46M55.14M43.93M19.22M10.56M8.04M
EBITDA-3.03M-22.02M-30.47M-36.39M-24.09M-23.98M
Net Income-31.43M-38.07M-43.10M-44.04M-29.00M-28.66M
Balance Sheet
Total Assets154.28M157.33M129.13M119.14M75.07M31.86M
Cash, Cash Equivalents and Short-Term Investments32.01M46.80M22.38M15.60M58.59M15.95M
Total Debt87.91M60.06M41.27M39.79M15.56M15.87M
Total Liabilities162.54M142.49M121.92M109.82M28.17M26.01M
Stockholders Equity-8.26M14.84M7.21M9.31M46.90M5.85M
Cash Flow
Free Cash Flow-6.98M-20.69M-26.52M-38.28M-23.44M-20.78M
Operating Cash Flow-5.68M-18.53M-21.50M-34.12M-22.55M-20.24M
Investing Cash Flow-20.58M-1.64M-3.93M-29.04M-885.00K-537.00K
Financing Cash Flow9.00M44.60M32.28M20.72M66.50M14.29M

MDxHealth Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.45
Price Trends
50DMA
4.30
Negative
100DMA
3.53
Negative
200DMA
2.67
Positive
Market Momentum
MACD
-0.25
Positive
RSI
26.53
Positive
STOCH
16.33
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MDXH, the sentiment is Negative. The current price of 4.45 is above the 20-day moving average (MA) of 4.35, above the 50-day MA of 4.30, and above the 200-day MA of 2.67, indicating a neutral trend. The MACD of -0.25 indicates Positive momentum. The RSI at 26.53 is Positive, neither overbought nor oversold. The STOCH value of 16.33 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for MDXH.

MDxHealth Risk Analysis

MDxHealth disclosed 57 risk factors in its most recent earnings report. MDxHealth reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

MDxHealth Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
$121.79M-6.04-22.66%5.33%75.52%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$60.46M-1.42-302.55%22.29%31.93%
44
Neutral
$235.61M-5.44-720.01%21.68%58.30%
42
Neutral
$179.28M-23.93%159.45%8.59%
41
Neutral
$118.75M-47.69%1.06%22.41%
38
Underperform
$179.27M-122.81%14.08%1.34%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MDXH
MDxHealth
3.26
1.38
73.40%
XGN
Exagen
7.91
3.81
92.93%
BNR
Burning Rock Biotech
16.03
10.43
186.25%
BDSX
Biodesix
6.90
-18.70
-73.05%
PRE
Prenetics Group
12.71
8.29
187.56%
SERA
Sera Prognostics
3.20
-3.34
-51.07%

MDxHealth Corporate Events

Mdxhealth Reports Strong Q3 Growth and Strategic Acquisition
Nov 12, 2025

On November 12, 2025, Mdxhealth reported an 18% increase in Q3 revenues to $27.4 million and achieved an adjusted EBITDA profitability of $1.0 million. The company highlighted the strategic acquisition of Exosome Diagnostics from Bio-Techne on September 15, 2025, which is expected to enhance its market positioning by integrating the ExoDx business. Despite suspending its germline product introduction, Mdxhealth reaffirmed its full-year revenue guidance, anticipating growth to meet or exceed 20%. The acquisition and expansion of its sales organization are seen as significant steps towards capitalizing on cross-selling opportunities and strengthening its precision diagnostics offerings.

MDxHealth Completes Acquisition of Exosome Diagnostics
Sep 16, 2025

On September 15, 2025, MDxHealth SA announced the completion of its acquisition of Exosome Diagnostics, Inc. from Bio-Techne Corporation, which includes the ExoDx Prostate test. The acquisition, initially agreed upon on August 5, 2025, involves a total consideration of $15 million, with $5 million paid in stock at closing and the remainder to be paid over the next four years. This strategic acquisition is expected to enhance MDxHealth’s market position in precision diagnostics and expand its offerings in the urologic cancer diagnostics sector.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 18, 2025