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VolitionRX Ltd. (VNRX)
XASE:VNRX
US Market

VolitionRX (VNRX) AI Stock Analysis

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VNRX

VolitionRX

(NYSE MKT:VNRX)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$0.35
▲(10.00% Upside)
The score is held down primarily by weak financials—large ongoing losses, heavy cash burn, and a balance sheet with negative equity that heightens financing and dilution risk. Offsetting this, the earnings call pointed to improving commercialization momentum and cost control through partnerships, while technicals show a short-term rebound but not a confirmed long-term trend reversal. Valuation remains constrained by lack of profitability and no dividend support.
Positive Factors
Veterinary product breakthrough
A validated, high‑accuracy blood test for feline lymphoma materially expands Volition's addressable market into veterinary diagnostics, creating a new recurring revenue stream and diversification that can provide more stable test-volume income and partnerships less correlated with human diagnostic reimbursement cycles.
Werfen partnership (APS)
The Werfen agreement grants commercial option rights into an ~ $85M annual APS market, providing a pathway to third‑party distribution and validation. Such an OEM/licensing route can scale adoption faster than direct sales, leveraging an established lab channel to convert Nu.Q into sustained commercial revenues.
Hologic co-marketing agreement
A co-marketing tie with a major diagnostics company like Hologic provides distribution reach, clinical credibility, and potential recurring service revenue. This kind of channel partnership supports more efficient commercialization and can materially shorten sales cycles across clinical labs and hospital networks.
Negative Factors
Negative equity
Negative shareholders' equity signals accumulated losses and weak solvency metrics, constraining the company's ability to raise debt on favorable terms and increasing dilution risk from equity financing. This structural weakness limits long‑term financial flexibility and heightens dependency on external capital.
Persistent cash burn
Sustained large negative operating and free cash flows mean the business cannot self‑fund growth or commercialization. Over the medium term this necessitates repeat capital raises or licensing monetization; both can dilute shareholders or delay product rollouts if funding conditions tighten.
Lumpy revenue and licensing timing
Unpredictable, lumpy revenue and uncertain timelines for closing licensing deals impair planning, make cash flows volatile, and hinder progress toward break‑even. For a commercialization‑stage diagnostics firm, reliable licensing and recurring test volumes are essential to sustain operations and justify ongoing investment.

VolitionRX (VNRX) vs. SPDR S&P 500 ETF (SPY)

VolitionRX Business Overview & Revenue Model

Company DescriptionVolitionRx Limited, a multi-national epigenetics company, engages in the development of blood tests to help diagnose a range of cancers and other diseases worldwide. It sells Nu.Q that detect cancer; Nu.Q Nets, monitoring the immune system; Nu.Q Vet cancer screening test for veterinary applications; Nu.Q Capture capturing and concentrating samples for more accurate diagnosis; and Nu.Q Discover, a solution to profiling nucleosomes. The company operates Nucleosomics a technology platform for blood test. VolitionRx Limited is based in Austin, Texas.
How the Company Makes MoneyVolitionRX generates revenue primarily through the commercialization of its cancer diagnostic tests, which are sold to laboratories and healthcare providers. The company has established partnerships with various laboratories and healthcare institutions to facilitate the adoption of its tests in clinical settings. Additionally, VolitionRX may receive funding through grants and collaborations with research organizations or pharmaceutical companies, further supporting its product development and market expansion efforts. The revenue model is centered on test sales, with potential for recurring revenue as more healthcare providers adopt their diagnostics.

VolitionRX Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 31, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant progress in revenue growth, cost management, and strategic partnerships with major companies like Werfen and Hologic. Scientific advancements also promise future potential. However, challenges remain, such as unpredictable revenue and uncertainty in closing additional licensing agreements.
Q3-2025 Updates
Positive Updates
Revenue Growth
Revenue for the third quarter grew 32% over the same quarter last year, reaching $0.6 million.
Cost Management
Operating expenses for the quarter were down 10% year-on-year and down 18% for the first three quarters.
Partnership with Werfen
VolitionRx signed a research license and exclusive commercial option rights agreement with Werfen for antiphospholipid syndrome (APS), potentially opening a market of approximately $85 million annually.
Partnership with Hologic
A co-marketing and service agreement with Hologic to promote Nu.Q Discover services, leading to the first sale by Hologic.
Scientific Advancements
Significant progress in the Capture-Seq project, potentially a revolutionary new liquid biopsy method for cancer detection.
Cash Flow Improvement
Net cash used in operating activities was $3.6 million for the quarter, down 33% over the same period last year.
Negative Updates
Lumpy Revenue
Revenues remain fairly lumpy and difficult to predict from one quarter to the next, leading to no revenue guidance being provided.
Licensing Agreement Delays
While multiple licensing discussions are ongoing, exact timelines for closing additional agreements remain uncertain.
Company Guidance
During the third quarter 2025 earnings call, VolitionRx Limited provided guidance focusing on their strategic efforts and partnerships. The company emphasized the commercialization of their Nu.Q platform, highlighting two significant agreements: a research license and exclusive commercial option rights agreement with Werfen for antiphospholipid syndrome (APS) and a co-marketing and service agreement with Hologic. With an APS market potential of approximately $85 million annually, the partnerships are expected to leverage Volition's unique NETs platform. The company's financial performance showed a 32% increase in revenue compared to the previous year, reaching $0.6 million, while operating expenses decreased by 10%. Additionally, Volition received $1.2 million from a registered direct offering and approximately $6.1 million from a public offering after the quarter's end. The company aims to achieve cash neutrality through licensing deals in human and veterinary spaces and anticipates further growth from these strategic collaborations and ongoing discussions with potential partners.

VolitionRX Financial Statement Overview

Summary
VolitionRX is facing significant financial challenges across all verticals. The company shows growth in revenue but struggles with profitability and cash flow management. The balance sheet reflects financial instability with negative equity, and cash flow statements indicate ongoing cash burn. While there are minor improvements in certain areas, the overall financial health remains weak, requiring strategic interventions to stabilize and improve financial performance.
Income Statement
VolitionRX's income statement reveals a challenging financial position with consistently negative net profit margins and EBIT margins over the years. Despite a positive revenue growth trend, the company struggles with profitability, as indicated by negative EBIT and EBITDA margins. The TTM data shows a slight improvement in net profit margin compared to previous years, but the overall profitability remains weak.
Balance Sheet
The balance sheet indicates significant financial instability, with negative stockholders' equity and a concerning debt-to-equity ratio. The negative equity suggests potential solvency issues, and the high return on equity is misleading due to negative equity values. The equity ratio is also negative, highlighting the company's reliance on debt financing.
Cash Flow
Cash flow analysis shows persistent negative operating and free cash flows, indicating cash burn issues. The free cash flow to net income ratio is slightly above 1, suggesting that cash flow is somewhat aligned with net income, albeit negative. The TTM data shows a minor improvement in free cash flow growth, but overall cash flow health remains poor.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.47M1.23M775.30K306.39K90.03K13.43K
Gross Profit1.47M1.23M775.30K306.39K90.03K13.43K
EBITDA-20.26M-25.58M-34.04M-29.24M-25.69M-19.23M
Net Income-22.88M-26.97M-35.32M-30.27M-26.81M-20.35M
Balance Sheet
Total Assets6.45M9.40M27.95M18.30M27.49M26.15M
Cash, Cash Equivalents and Short-Term Investments199.41K3.26M20.73M10.87M20.58M19.44M
Total Debt11.26M5.82M5.86M4.97M4.02M4.44M
Total Liabilities42.40M35.51M36.66M21.42M9.77M9.86M
Stockholders Equity-34.64M-24.91M-7.80M-2.57M17.94M16.34M
Cash Flow
Free Cash Flow-19.74M-26.47M-19.15M-16.85M-21.83M-18.41M
Operating Cash Flow-19.47M-25.89M-18.06M-15.28M-20.85M-16.46M
Investing Cash Flow-276.45K-573.85K-1.08M-1.57M-973.56K-1.65M
Financing Cash Flow13.09M8.66M28.98M6.94M22.86M20.62M

VolitionRX Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price0.32
Price Trends
50DMA
0.31
Positive
100DMA
0.45
Negative
200DMA
0.52
Negative
Market Momentum
MACD
<0.01
Negative
RSI
55.88
Neutral
STOCH
63.79
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For VNRX, the sentiment is Neutral. The current price of 0.32 is above the 20-day moving average (MA) of 0.27, above the 50-day MA of 0.31, and below the 200-day MA of 0.52, indicating a neutral trend. The MACD of <0.01 indicates Negative momentum. The RSI at 55.88 is Neutral, neither overbought nor oversold. The STOCH value of 63.79 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for VNRX.

VolitionRX Risk Analysis

VolitionRX disclosed 35 risk factors in its most recent earnings report. VolitionRX reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

VolitionRX Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$252.44M-14.97-19.87%5.44%72.17%
56
Neutral
$45.66M-30.80-9.76%30.95%59.67%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$64.28M-1.84-302.55%22.29%31.93%
49
Neutral
$41.75M14.48%36.83%
41
Neutral
$13.28M-0.30-4.35%-6.31%
40
Underperform
$16.18M-0.10-78.22%-13.84%88.80%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
VNRX
VolitionRX
0.32
-0.35
-52.27%
TRIB
Trinity Biotech
0.70
-0.06
-8.34%
PRPO
Precipio
25.71
19.65
324.24%
BNGO
BioNano Genomics
1.58
-10.73
-87.16%
BNR
Burning Rock Biotech
24.07
17.27
253.97%
BDSX
Biodesix
9.88
-12.72
-56.28%

VolitionRX Corporate Events

Business Operations and StrategyExecutive/Board Changes
VolitionRX Announces CEO Departure Amid Cost Realignment
Neutral
Dec 11, 2025

On December 5, 2025, Volition Veterinary Diagnostics Development, a subsidiary of VolitionRx Limited, announced the termination of its employment agreement with CEO Dr. Salvatore Thomas Butera, effective January 31, 2026. This decision is part of the company’s cost-realignment efforts, leading to the elimination of the CEO position and redistribution of duties within the company. Dr. Butera is expected to continue with the company on a part-time consulting basis after the termination.

The most recent analyst rating on (VNRX) stock is a Buy with a $1.50 price target. To see the full list of analyst forecasts on VolitionRX stock, see the VNRX Stock Forecast page.

Private Placements and Financing
VolitionRX Amends Underwriting Agreement for Stock Offering
Neutral
Nov 7, 2025

On October 10, 2025, VolitionRx Limited entered into an Underwriting Agreement with Newbridge Securities Corporation for a public offering of 11,550,000 shares of common stock, along with warrants for an equal number of shares. The offering was priced at $0.52 per share, including a $0.01 warrant, with a 7% underwriting discount. On November 7, 2025, an amendment to the agreement allowed the underwriter to exercise an over-allotment option for 1,194,000 shares and 1,732,500 warrants at the same price, enhancing flexibility in the offering.

The most recent analyst rating on (VNRX) stock is a Sell with a $0.50 price target. To see the full list of analyst forecasts on VolitionRX stock, see the VNRX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 09, 2026