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Bionano Genomics (BNGO)
NASDAQ:BNGO
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BioNano Genomics (BNGO) AI Stock Analysis

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BNGO

BioNano Genomics

(NASDAQ:BNGO)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$1.00
▼(-38.27% Downside)
Action:Reiterated
Date:05/29/26
The score is held back primarily by weak financial performance (shrinking TTM revenue, very large losses, and continued negative free cash flow). Offsetting this, the latest earnings call points to improving commercialization metrics, margin progress, and reaffirmed 2026 growth guidance, while technicals suggest only early stabilization rather than a confirmed uptrend. Valuation offers limited support due to ongoing losses and no stated dividend.
Positive Factors
Consumables & installed-base pull-through
Recurring consumables growth (+20% YoY) indicates stronger installed-base utilization and creates a more predictable, annuity-like revenue stream. Durable consumables pull-through scales with instrument placements, supporting revenue stability and margin leverage as adoption broadens over months.
Negative Factors
Shrinking revenue & weak profitability
Material revenue decline and deeply negative operating margins signal the business remains far from scale economics. Structural profitability is contingent on sustained top-line recovery and mix shift; until then, continued losses erode equity and constrain reinvestment into sales, R&D, and commercialization.
Read all positive and negative factors
Positive Factors
Negative Factors
Consumables & installed-base pull-through
Recurring consumables growth (+20% YoY) indicates stronger installed-base utilization and creates a more predictable, annuity-like revenue stream. Durable consumables pull-through scales with instrument placements, supporting revenue stability and margin leverage as adoption broadens over months.
Read all positive factors

BioNano Genomics Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Shows how much revenue each business segment generates, highlighting which areas drive growth and which may need strategic adjustments.
Chart InsightsBioNano Genomics' Product segment shows a steady revenue increase, reflecting strong demand and record flow cell sales. However, the Service and Other segment has sharply declined, suggesting strategic challenges. The latest earnings call highlights a 21% revenue growth in Q3 2025 and improved gross margins, but also notes limited new system installations and slow market uptake in Japan. Despite these hurdles, the company maintains a robust cash position and reiterates its revenue guidance, indicating confidence in its strategic direction.
Data provided by:The Fly

BioNano Genomics (BNGO) vs. SPDR S&P 500 ETF (SPY)

BioNano Genomics Business Overview & Revenue Model

Company Description
Bionano Genomics, Inc. provides genome analysis software solutions. It offers Saphyr, a sample-to-result solution for structural variation analysis by optical genome mapping for genome analysis and understanding of genetic variation and function; ...
How the Company Makes Money
BioNano Genomics primarily makes money by selling and supporting an instrument-led consumables model centered on its optical genome mapping platform. Key revenue streams include: (1) Instrument sales: upfront revenue from selling OGM instruments (...

BioNano Genomics Earnings Call Summary

Earnings Call Date:May 13, 2026
(Q1-2026)
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% Change Since: |
Next Earnings Date:Jul 30, 2026
Earnings Call Sentiment Positive
The call emphasized multiple positive operational and commercial developments: record Q1 flow cell unit sales, strong consumables growth, improved adjusted gross margin (49% vs 46% YoY), meaningful reimbursement wins that materially improve test economics, growing publication and clinical validation momentum, and balance sheet simplification through planned debt retirement. Offsetting these positives are continued revenue lumpiness (notably a 40% decline in software revenue due to a prior large sale), ongoing supply constraints that are improving, increased operating expenses ($9.1M vs $8.5M YoY) and a cash runway into 2027 with management not expecting cash flow breakeven in 2026. Overall, the call portrays improving commercialization traction and margin progress with material near-term financial and execution risks that management is addressing.
Positive Updates
Revenue Growth and Guidance Reaffirmed
Q1 2026 revenue was $6.7 million, up 4% year-over-year and at the high end of guidance ($6.5M–$6.7M). Company reaffirmed full-year 2026 revenue guidance of $30M–$33M (growth of 5%–16% over 2025) and initiated Q2 2026 guidance of $7.5M–$7.8M (up 12%–16% vs Q2 2025).
Negative Updates
Large Decline in Software Revenue (Lumpy Sales)
Software revenue was $1.2 million in Q1 2026, down 40% year-over-year. Management explained this decline was driven by a very large software sale in the prior year that is expected to cover customer needs across 2025–2026, highlighting revenue lumpiness in software sales.
Read all updates
Q1-2026 Updates
Negative
Revenue Growth and Guidance Reaffirmed
Q1 2026 revenue was $6.7 million, up 4% year-over-year and at the high end of guidance ($6.5M–$6.7M). Company reaffirmed full-year 2026 revenue guidance of $30M–$33M (growth of 5%–16% over 2025) and initiated Q2 2026 guidance of $7.5M–$7.8M (up 12%–16% vs Q2 2025).
Read all positive updates
Company Guidance
Bionano reaffirmed full‑year 2026 revenue guidance of $30.0–$33.0 million (up 5%–16% vs. 2025) and initiated Q2 guidance of $7.5–$7.8 million (up 12%–16% vs. Q2 2025); Q1 revenue was $6.7 million (at the high end of prior $6.5–$6.7M guidance). Key operational and profitability metrics supporting the outlook include 8,178 flow cells sold in Q1 (up 17% YoY and +21% to existing customers excluding new system sales), consumables revenue of $3.9M (up 20% YoY), software revenue of $1.2M (down 40% YoY), other revenue of $1.6M (up 36% YoY), adjusted gross margin of 49% (vs. 46% in Q1 2025) and adjusted operating expense of $9.1M (vs. $8.5M). The company ended Q1 with $24.7M in cash and equivalents (including $10.3M restricted), expects cash runway into 2027, plans to retire its senior secured convertible debt this month, does not expect cash‑flow breakeven in 2026 (aims to reduce burn toward Q4 2027), and cited strong reimbursement catalysts including a 47% increase in the hematologic malignancy CPT payment to $1,853.22 and a new constitutional OGM CPT payment determination of $1,263.53 effective Jan 1, 2026.

BioNano Genomics Financial Statement Overview

Summary
Fundamentals remain weak despite improvement: TTM revenue declined ~22.6%, gross margin is low (~15.1%), and profitability is deeply negative (EBIT margin ~-137%, net margin ~-106%). Cash flow is still materially negative (TTM FCF about -$19.3M), implying continued reliance on external capital. Balance sheet leverage is currently manageable with low absolute debt and improved debt-to-equity (~0.45), but equity erosion and deeply negative ROE (~-56%) keep overall financial quality constrained.
Income Statement
18
Very Negative
Balance Sheet
44
Neutral
Cash Flow
22
Negative
BreakdownTTMDec 2025Mar 2025Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue28.74M28.51M30.78M36.12M27.80M17.98M
Gross Profit13.50M6.26M380.00K9.57M5.95M3.87M
EBITDA-23.27M-23.61M-97.47M-213.60M-120.31M-73.86M
Net Income-31.60M-26.39M-112.02M-232.49M-132.60M-72.44M
Balance Sheet
Total Assets64.80M73.58M76.67M214.40M307.50M377.10M
Cash, Cash Equivalents and Short-Term Investments24.67M13.26M9.47M66.77M113.19M250.61M
Total Debt17.01M6.92M27.30M79.41M11.67M10.70M
Total Liabilities27.34M29.16M41.30M118.25M58.10M39.98M
Stockholders Equity37.46M44.42M35.38M96.16M249.40M337.12M
Cash Flow
Free Cash Flow-19.30M-16.34M-69.03M-126.87M-128.12M-73.39M
Operating Cash Flow-19.30M-16.34M-68.92M-125.18M-124.82M-71.93M
Investing Cash Flow6.78M-12.75M73.84M24.16M82.77M-278.06M
Financing Cash Flow13.80M24.04M-13.69M113.81M23.01M336.11M

BioNano Genomics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1.62
Price Trends
50DMA
1.22
Positive
100DMA
1.25
Negative
200DMA
1.72
Negative
Market Momentum
MACD
<0.01
Negative
RSI
52.49
Neutral
STOCH
64.02
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BNGO, the sentiment is Positive. The current price of 1.62 is above the 20-day moving average (MA) of 1.23, above the 50-day MA of 1.22, and below the 200-day MA of 1.72, indicating a neutral trend. The MACD of <0.01 indicates Negative momentum. The RSI at 52.49 is Neutral, neither overbought nor oversold. The STOCH value of 64.02 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for BNGO.

BioNano Genomics Risk Analysis

BioNano Genomics disclosed 83 risk factors in its most recent earnings report. BioNano Genomics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioNano Genomics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$518.03M-7.59-6.70%9.54%-79.16%
56
Neutral
$161.64M-4.93-2101.40%29.05%29.88%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$1.15B-12.43-43.52%-24.71%21.16%
49
Neutral
$14.34M-0.21-71.38%0.96%91.13%
49
Neutral
$398.57M-0.93-109.09%-0.28%-286.80%
44
Neutral
$106.23M-1.19-9.93%4.69%84.60%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BNGO
BioNano Genomics
1.24
-2.43
-66.21%
MYGN
Myriad Genetics
3.97
-0.22
-5.25%
FLGT
Fulgent Genetics
18.14
-2.58
-12.45%
PSNL
Personalis
11.40
6.77
146.22%
BNR
Burning Rock Biotech
9.32
6.22
200.65%
BDSX
Biodesix
16.32
10.28
170.20%

BioNano Genomics Corporate Events

Business Operations and StrategyFinancial DisclosuresRegulatory Filings and Compliance
BioNano Genomics Retires Secured Debt, Boosts Flexibility
Positive
May 28, 2026
On May 28, 2026, Bionano Genomics, Inc. announced that it had fully retired and cancelled all of its outstanding Senior Secured Convertible Debentures, which had an aggregate face value of $20 million and were originally issued in May 2024. The co...
Executive/Board ChangesShareholder Meetings
BioNano Genomics Stockholders Approve 2026 Annual Meeting Proposals
Neutral
May 14, 2026
On May 14, 2026, Bionano Genomics, Inc. held its 2026 Annual Meeting of Stockholders, with 4,225,995 shares represented, or about 38.1% of shares outstanding and entitled to vote as of the March 19, 2026 record date. Shareholders elected Albert Lu...
Executive/Board Changes
BioNano Genomics Names Interim CEO Amid Leadership Transition
Negative
May 6, 2026
On May 5, 2026, Bionano Genomics terminated R. Erik Holmlin as president and chief executive officer, and he simultaneously resigned from the board, with severance to be provided under his employment agreement and an expected consulting role to su...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 29, 2026