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Bionano Genomics (BNGO)
NASDAQ:BNGO

BioNano Genomics (BNGO) AI Stock Analysis

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BNGO

BioNano Genomics

(NASDAQ:BNGO)

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Neutral 44 (OpenAI - 5.2)
Rating:44Neutral
Price Target:
$1.50
▼(-7.41% Downside)
The score is held down primarily by weak financial performance (large losses, low gross margin, and deteriorating free cash flow) and a bearish technical trend with the stock below major moving averages. The latest earnings call is a relative positive due to improved margins, reduced expenses, and reiterated guidance, but it is not yet strong enough to outweigh the broader profitability, cash flow, and trend concerns.
Positive Factors
Recurring consumables growth (flow cells)
Record flow-cell sales show rising utilization of existing Saphyr systems and strengthen the consumables revenue stream. Recurring consumables scale with installed base, creating predictable, higher-margin revenue and improving lifetime value per customer if adoption and usage remain sustained.
Non-GAAP gross margin improvement
A durable move from 26% to 46% non-GAAP gross margin suggests better product mix, pricing or cost controls. If sustained, higher gross margins materially improve the pathway to operating profitability and reduce dependency on external financing to fund operations and growth investments.
Significant operating expense reductions
A 40% cut in operating expenses reflects structural cost discipline that can lower the burn rate and extend runway. Sustained lower OpEx increases the probability of achieving positive cash flow from operations and provides management flexibility to invest selectively in commercialization and R&D.
Negative Factors
Persistently negative GAAP profitability
Deeply negative GAAP margins indicate the business still incurs structural losses after accounting for all costs. Until GAAP profitability improves, the company faces ongoing capital needs, weaker returns on equity, and limited ability to self-fund growth initiatives or absorb market setbacks.
Weak free cash flow trends
Declining free cash flow and negative operating cash conversion show persistent cash burn that erodes financial flexibility. Over months, continued negative FCF forces reliance on financing, which can dilute shareholders and constrain investment in sales, service, and product development necessary for scale.
Limited installed-base growth and slow regional adoption
Modest net additions to the installed base and slow uptake in Japan constrain long-term recurring consumables growth and scale economics. Installed-base expansion is the primary driver of recurring revenue; slow system placements lengthen the time to achieve sustainable revenue growth and operating leverage.

BioNano Genomics (BNGO) vs. SPDR S&P 500 ETF (SPY)

BioNano Genomics Business Overview & Revenue Model

Company DescriptionBionano Genomics, Inc. provides genome analysis software solutions. It offers Saphyr, a sample-to-result solution for structural variation analysis by optical genome mapping for genome analysis and understanding of genetic variation and function; Saphyr instrument, a single-molecule imager; Saphyr Chip, a consumable that packages the nanochannel arrays for DNA linearization; and Bionano Prep Kits and DNA labeling kits, which provide the reagents and protocols for extracting and labeling ultra-high molecular weight. The company also provides Saphyr and Bionano compute servers; and NxClinical which offers one system for analysis and interpretation of genomic variants from microarray and next-generation sequencing data for cytogenetics and molecular genetics. In addition, it offers testing and laboratory services comprising FirstStepDx PLUS, a chromosomal microarray for identifying an underlying genetic cause in individuals with autism spectrum disorder, developmental delay, and intellectual disability; Fragile X syndrome (FXS) testing services; NextStepDx PLUS, a exome sequencing test to identify genetic variants that are associated with disorders of childhood development; EpiPanelDx PLUS, a genetic testing panel for patients who have experienced seizures, infantile spasms, encephalopathy, or febrile seizures; PGx test, which identifies over 60 alleles in 11 genes. The company was founded in 2003 and is headquartered in San Diego, California.
How the Company Makes MoneyBioNano Genomics generates revenue primarily through the sale of its Saphyr systems, consumables, and software solutions. The company has established a revenue model that includes the direct sale of its hardware and ongoing sales of consumables that are required for the operation of the Saphyr system. Additionally, BNGO benefits from software licensing and support services associated with their genomic analysis products. Significant partnerships with academic and research institutions, as well as collaborations with biopharmaceutical companies, contribute to its revenue by expanding the adoption of its technology in various research applications and clinical settings. The company may also receive funding through grants and strategic collaborations that support its product development and market expansion efforts.

BioNano Genomics Key Performance Indicators (KPIs)

Any
Any
Gross Profit by Segment
Gross Profit by Segment
Reveals the profitability of each segment, indicating where the company is most efficient and where costs might be impacting margins.
Chart InsightsBioNano Genomics' gross profit from the Product segment experienced a dramatic dip in Q3 2024, reflecting broader revenue challenges due to discontinued services. However, the subsequent recovery aligns with strategic cost reductions and improved gross margins. The Service and Other segment also faced volatility, with recent losses highlighting ongoing challenges. Despite these fluctuations, the company is optimistic, driven by strong flowcell sales, enhanced software and consumables revenue, and new CPT codes that may boost future reimbursement opportunities. Investors should watch for sustained improvements in these areas as potential growth drivers.
Data provided by:The Fly

BioNano Genomics Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 05, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue growth, record flow cell sales, and improved gross margins, with significant reductions in operating expenses. However, challenges include limited new system installations and slow market evolution in Japan. Cash reserves are solid, but a portion is restricted.
Q3-2025 Updates
Positive Updates
Revenue Growth
Total revenue for Q3 2025 was $7.4 million, reflecting an increase of 21% compared to Q3 2024.
Flow Cells Sales Record
Sold an all-time record of 8,390 flow cells in Q3 2025, a 7% increase compared to the same period last year.
Gross Margin Improvement
Non-GAAP gross margin for Q3 2025 was 46%, up from 26% in Q3 2024.
Operating Expense Reduction
Non-GAAP operating expense for Q3 2025 was $9.7 million, a 40% reduction compared to $16.1 million in Q3 2024.
Cash Position Strengthened
Ended Q3 2025 with $31.8 million in cash, cash equivalents, and available-for-sale securities.
Expansion of Optical Genome Mapping (OGM)
97 new publications in Q3 2025 demonstrated the value of OGM, a 10% growth over the same period last year.
Negative Updates
Limited Installed Base Growth
Installed 7 new systems and brought 1 back for a net increase of 3, totaling 384 systems by the end of Q3 2025.
Cash Restrictions
Of the $31.8 million in cash, $10.3 million was subject to certain restrictions.
Japanese Market Slow to Ramp
Only 1 system installed in Japan, with the market evolving slower compared to other regions.
Company Guidance
In the third quarter of 2025, Bionano reported a total revenue of $7.4 million, marking a 21% increase compared to the same period in 2024. When adjusted for a prior $0.5 million write-down, core revenues grew 12% year-over-year. The company sold an all-time record of 8,390 flow cells, reflecting a 7% increase from the previous year, driven by increased utilization among routine users. Non-GAAP gross margin rose to 46%, up from 26% in Q3 2024, and operating expenses decreased by 40% to $9.7 million. The installed base expanded with seven new systems and a net increase of three, totaling 384 systems. The company ended the quarter with $31.8 million in cash and equivalents, following a $10 million public offering in September. Bionano reiterated its full-year revenue guidance of $26 million to $30 million and expects Q4 revenues between $7.5 million and $7.9 million.

BioNano Genomics Financial Statement Overview

Summary
Revenue is growing (4.72% TTM), but fundamentals remain weak with deeply negative profitability (net margin -271.02%) and low gross margin (5.05%). Leverage is improved (debt-to-equity 0.43), but cash flow trends are unfavorable (free cash flow growth -28.35% TTM) and overall financial stability is still pressured.
Income Statement
35
Negative
BioNano Genomics shows a modest revenue growth rate of 4.72% TTM, but profitability remains a significant concern with a net profit margin of -271.02% and negative EBIT and EBITDA margins. The gross profit margin is low at 5.05%, indicating challenges in cost management. Overall, the company struggles with profitability despite some revenue growth.
Balance Sheet
40
Negative
The company's debt-to-equity ratio has improved to 0.43 TTM, reflecting better leverage management compared to previous years. However, the return on equity remains negative at -167.22%, indicating ongoing profitability issues. The equity ratio is not provided, but the balance sheet shows a need for improved financial stability.
Cash Flow
30
Negative
Free cash flow growth is negative at -28.35% TTM, and the operating cash flow to net income ratio is -1.08, highlighting cash flow challenges. The free cash flow to net income ratio is 1.0, indicating that free cash flow aligns with net income, but both are negative, reflecting cash flow difficulties.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue28.72M30.78M36.12M27.80M17.98M8.50M
Gross Profit13.36M380.00K9.57M5.95M3.87M2.77M
EBITDA-28.58M-97.47M-213.60M-120.31M-73.86M-35.57M
Net Income-38.59M-112.02M-232.49M-132.60M-72.44M-41.11M
Balance Sheet
Total Assets79.06M76.67M214.40M307.50M377.10M60.45M
Cash, Cash Equivalents and Short-Term Investments3.06M9.47M66.77M113.19M250.61M38.45M
Total Debt7.37M27.30M79.41M11.67M10.70M16.32M
Total Liabilities29.26M41.30M118.25M58.10M39.98M25.37M
Stockholders Equity49.80M35.38M96.16M249.40M337.12M35.08M
Cash Flow
Free Cash Flow-18.67M-69.03M-126.87M-128.12M-73.39M-38.31M
Operating Cash Flow-18.67M-68.92M-125.18M-124.82M-71.93M-38.31M
Investing Cash Flow-13.76M73.84M24.16M82.77M-278.06M-2.45M
Financing Cash Flow26.33M-13.69M113.81M23.01M336.11M61.90M

BioNano Genomics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.62
Price Trends
50DMA
1.57
Negative
100DMA
1.71
Negative
200DMA
2.66
Negative
Market Momentum
MACD
-0.09
Positive
RSI
26.20
Positive
STOCH
9.36
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BNGO, the sentiment is Negative. The current price of 1.62 is above the 20-day moving average (MA) of 1.49, above the 50-day MA of 1.57, and below the 200-day MA of 2.66, indicating a bearish trend. The MACD of -0.09 indicates Positive momentum. The RSI at 26.20 is Positive, neither overbought nor oversold. The STOCH value of 9.36 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BNGO.

BioNano Genomics Risk Analysis

BioNano Genomics disclosed 82 risk factors in its most recent earnings report. BioNano Genomics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioNano Genomics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$355.19M-20.52-19.87%5.44%72.17%
53
Neutral
$789.19M-18.21-3.80%13.60%74.64%
53
Neutral
$737.96M-9.49-43.69%-21.02%47.74%
52
Neutral
$81.94M-1.92-302.55%22.29%31.93%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
$12.06M-0.08-78.22%-13.84%88.80%
41
Neutral
$494.03M-1.22-72.52%0.21%-233.51%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BNGO
BioNano Genomics
1.19
-4.54
-79.28%
MYGN
Myriad Genetics
5.30
-7.43
-58.37%
FLGT
Fulgent Genetics
25.53
8.96
54.07%
PSNL
Personalis
8.31
3.15
61.05%
BNR
Burning Rock Biotech
32.99
26.67
421.99%
BDSX
Biodesix
10.30
-10.50
-50.48%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 31, 2026