tiprankstipranks
Trending News
More News >
BioNano Genomics Inc (BNGO)
NASDAQ:BNGO
Advertisement

BioNano Genomics (BNGO) AI Stock Analysis

Compare
9,199 Followers

Top Page

BNGO

BioNano Genomics

(NASDAQ:BNGO)

Rating:50Neutral
Price Target:
$4.00
▲(0.25% Upside)
BioNano Genomics' overall stock score is primarily impacted by its weak financial performance, characterized by declining revenues and profitability challenges. While technical analysis shows some short-term strength, the valuation remains unattractive due to negative earnings. The earnings call provides a cautiously optimistic outlook with strategic advancements, but significant risks remain.
Positive Factors
Market Position
Bionano shares are currently trading at an EV/Revenue multiple of 0.2x, which is less than one tenth of comparable companies’ average multiple of 3.5x.
Regulatory Approval
The editorial panel of the American Medical Association (AMA) established a second Category I Current Procedural Terminology (CPT) code for the use of OGM in cytogenomic genome-wide analysis to detect structural and copy number variations relative to constitutional genetic disorders.
Technology Advancements
New versions of VIA and Solve software enhance capabilities, part of Bionano's strategy to broaden its utilization by enhancing software capabilities that streamline data reporting and analysis for OGM.
Negative Factors
Market Challenges
Bionano reduced its 2025 revenue guidance, reflecting challenges in the U.S. life science space.
Revenue Decline
Total revenue was $6.7M, representing 13% YoY decline and missing our projection of $7.4M.
Revenue Guidance
Bionano's full year revenue guidance of $26M-$30M is lower than the previous year's $30.8M, indicating a cautious outlook.

BioNano Genomics (BNGO) vs. SPDR S&P 500 ETF (SPY)

BioNano Genomics Business Overview & Revenue Model

Company DescriptionBionano Genomics, Inc. provides genome analysis software solutions. It offers Saphyr, a sample-to-result solution for structural variation analysis by optical genome mapping for genome analysis and understanding of genetic variation and function; Saphyr instrument, a single-molecule imager; Saphyr Chip, a consumable that packages the nanochannel arrays for DNA linearization; and Bionano Prep Kits and DNA labeling kits, which provide the reagents and protocols for extracting and labeling ultra-high molecular weight. The company also provides Saphyr and Bionano compute servers; and NxClinical which offers one system for analysis and interpretation of genomic variants from microarray and next-generation sequencing data for cytogenetics and molecular genetics. In addition, it offers testing and laboratory services comprising FirstStepDx PLUS, a chromosomal microarray for identifying an underlying genetic cause in individuals with autism spectrum disorder, developmental delay, and intellectual disability; Fragile X syndrome (FXS) testing services; NextStepDx PLUS, a exome sequencing test to identify genetic variants that are associated with disorders of childhood development; EpiPanelDx PLUS, a genetic testing panel for patients who have experienced seizures, infantile spasms, encephalopathy, or febrile seizures; PGx test, which identifies over 60 alleles in 11 genes. The company was founded in 2003 and is headquartered in San Diego, California.
How the Company Makes MoneyBioNano Genomics generates revenue primarily through the sale of its Saphyr systems, along with consumables and software licenses associated with its genomic analysis technology. The company has established key partnerships with academic institutions, research organizations, and clinical laboratories, which contribute to its revenue through collaborations and joint research initiatives. Additionally, BNGO may benefit from licensing agreements and collaborations with pharmaceutical companies looking to leverage its technology for drug development and precision medicine applications. The diverse applications of its optical genome mapping technology across various research and clinical settings enhance its potential revenue streams.

BioNano Genomics Earnings Call Summary

Earnings Call Date:Aug 14, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 13, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted strong growth in flowcell sales, improved gross margin, and significant reductions in operating expenses. However, the decline in total revenue and the net decrease in the installed base of systems were notable challenges. The overall sentiment is cautiously optimistic, with positive strategic advancements in software and consumables growth and new CPT codes that could support future reimbursement.
Q2-2025 Updates
Positive Updates
Increase in Flowcell Sales
Flowcell sales increased by 17% year-over-year, indicating strong demand and utilization among routine-use customers.
Improved Gross Margin
Non-GAAP gross margin increased significantly to 52% from 35% a year ago, showcasing improvements in product manufacturing costs and cost reduction efforts.
Reduction in Operating Expenses
Non-GAAP operating expenses were reduced by 53% year-over-year from $18.8 million to $8.8 million, reflecting cost efficiency measures.
Strong Software and Consumables Growth
Revenue from consumables and software grew 16% year-over-year in Q2 2025 and 8% for the first half of 2025, indicating increased utilization and customer retention.
New CPT Code for Optical Genome Mapping
A second Category I CPT code from the American Medical Association was established for OGM in evaluating constitutional genetic disorders, which could facilitate reimbursement.
Negative Updates
Decline in Total Revenue
Total revenue for Q2 2025 was $6.7 million, a decrease of 13% year-over-year, primarily due to the discontinuation of certain clinical services.
Net Decrease in Installed Base
There was a net decrease of 1 in the installed base of optical genome mapping systems, with 7 new installations and 8 systems being returned.
Limited VIA Software Adoption
VIA software is installed in only about one-third of OGM systems, indicating a significant opportunity for increased adoption and utilization.
Company Guidance
During the Bionano Second Quarter 2025 Earnings Conference Call, the company reported a total revenue of $6.7 million, reflecting a 13% decrease compared to the same period in 2024, primarily due to the discontinuation of certain services. However, upon adjusting for these discontinued services, the revenue decrease was 5% year-over-year. The company sold 7,233 flowcells, marking a 17% increase from the previous year, and achieved a non-GAAP gross margin of 52%, up from 35% a year ago. Non-GAAP operating expenses dropped by 53% year-over-year to $8.8 million, and the installed base of optical genome mapping systems experienced a net decrease to 378 systems. The company ended the quarter with $27.4 million in cash, cash equivalents, and available-for-sale securities. Bionano reiterated its full-year revenue guidance of $26 million to $30 million and increased its 2025 OGM installation expectations to a range of 20 to 25 new systems. The company is focusing on driving utilization among routine users, with consumables and software revenue rising to 73% of the total product mix in Q2 2025.

BioNano Genomics Financial Statement Overview

Summary
BioNano Genomics faces significant financial challenges, with declining revenues, negative profitability, and cash flow inefficiencies. While there is some improvement in leverage, the company struggles to generate positive returns and cash flows, posing risks to financial stability.
Income Statement
35
Negative
BioNano Genomics has experienced declining revenue growth, with a negative growth rate in the TTM period. The company shows weak profitability, with consistently negative net profit margins and EBIT margins. Gross profit margins are low, indicating challenges in cost management.
Balance Sheet
40
Negative
The company's debt-to-equity ratio has improved in the TTM period, suggesting better leverage management. However, the return on equity remains negative, indicating continued losses. The equity ratio is relatively stable, but the company faces challenges in generating returns for shareholders.
Cash Flow
30
Negative
BioNano Genomics shows negative free cash flow growth in the TTM period, reflecting cash flow challenges. The operating cash flow to net income ratio is negative, indicating inefficiencies in converting income to cash. The free cash flow to net income ratio is slightly above 1, showing some consistency in cash flow relative to net income.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue27.43M30.78M36.12M27.80M17.98M8.50M
Gross Profit1.39M380.00K9.57M5.95M3.87M2.77M
EBITDA-68.93M-97.47M-213.60M-120.31M-73.86M-37.08M
Net Income-74.33M-112.02M-232.49M-132.60M-72.44M-41.14M
Balance Sheet
Total Assets76.01M76.67M214.40M307.50M377.10M60.45M
Cash, Cash Equivalents and Short-Term Investments16.44M9.47M66.77M113.19M250.61M38.45M
Total Debt19.58M27.30M79.41M11.67M10.70M16.33M
Total Liabilities30.64M41.30M118.25M58.10M39.98M25.37M
Stockholders Equity45.37M35.38M96.16M249.40M337.12M35.08M
Cash Flow
Free Cash Flow-26.06M-69.03M-126.87M-128.12M-73.39M-38.31M
Operating Cash Flow-26.06M-68.92M-125.18M-124.82M-71.93M-38.31M
Investing Cash Flow-14.46M73.84M24.16M82.77M-278.06M-2.45M
Financing Cash Flow22.27M-13.69M113.81M23.01M336.11M61.90M

BioNano Genomics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price3.99
Price Trends
50DMA
3.40
Positive
100DMA
3.60
Positive
200DMA
6.08
Negative
Market Momentum
MACD
0.18
Negative
RSI
59.47
Neutral
STOCH
36.30
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BNGO, the sentiment is Positive. The current price of 3.99 is above the 20-day moving average (MA) of 3.58, above the 50-day MA of 3.40, and below the 200-day MA of 6.08, indicating a neutral trend. The MACD of 0.18 indicates Negative momentum. The RSI at 59.47 is Neutral, neither overbought nor oversold. The STOCH value of 36.30 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for BNGO.

BioNano Genomics Risk Analysis

BioNano Genomics disclosed 82 risk factors in its most recent earnings report. BioNano Genomics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioNano Genomics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$36.59M-13.95%
51
Neutral
$7.92B-0.43-41.67%2.21%22.29%-1.85%
51
Neutral
$90.93M-37.15%-0.26%60.09%
50
Neutral
$17.04M-118.26%-25.02%85.08%
48
Neutral
$13.65M-186.64%-1.90%87.72%
44
Neutral
$7.69M-809.29%
44
Neutral
$6.81M-1802.45%4.99%22.58%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BNGO
BioNano Genomics
3.99
-22.71
-85.06%
ENZB
Enzo Biochem
0.70
-0.34
-32.69%
BNR
Burning Rock Biotech
8.30
3.50
72.92%
INBS
Intelligent Bio Solutions
1.55
-0.24
-13.41%
MYNZ
Mainz Biomed B.V.
1.63
-13.17
-88.99%
BIAF
bioAffinity Technologies, Inc.
0.24
-1.15
-82.73%

BioNano Genomics Corporate Events

Executive/Board ChangesShareholder Meetings
BioNano Genomics Enhances Governance with New Appointment
Neutral
Jun 13, 2025

On June 10, 2025, BioNano Genomics appointed Kristiina Vuori, M.D., Ph.D., to its Audit Committee, enhancing its governance structure. During the company’s 2025 Annual Meeting of Stockholders on June 11, 2025, key decisions included the election of Class I Directors, approval of executive compensation, ratification of BDO USA, P.C. as the independent accounting firm, and approval of the issuance of shares upon exercise of purchase warrants, reflecting active shareholder engagement and strategic alignment with Nasdaq requirements.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 03, 2025