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Lexeo Therapeutics, Inc.
(NASDAQ:LXEO)
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Rating:46Neutral
Price Target:
$4.00
▼(-14.16% Downside)
Action:Reiterated
Date:06/30/26
LXEO scores low-to-mid primarily due to weak financial performance driven by minimal revenue, large ongoing losses, and deep negative operating/free cash flow, which outweigh the benefit of low leverage. Technicals also lean bearish with the price below key longer-term moving averages and negative MACD. Offsetting factors include generally positive recent corporate developments around advancing pivotal trial preparations and pipeline progress, but these do not fully mitigate the current cash-burn and trend risks.
Positive Factors
Regulatory pathway clarity / pivotal trial finalization
Finalizing the SUNRISE‑FA 2 protocol and FDA confirmation that no extra nonclinical bridging studies are required materially reduces regulatory and timeline uncertainty. Combined with commercial‑scale drug product on hand and an accelerated approval path, this structurally shortens time to potential approval and planning.
Negative Factors
Heavy cash burn
Sustained, deep negative operating and free cash flow indicate ongoing cash consumption from development activities. This structural burn rate pressures financing needs and limits flexibility to expand programs without external capital, raising dilution or funding‑risk over the next 12–24 months.
Read all positive and negative factors
Positive Factors
Negative Factors
Regulatory pathway clarity / pivotal trial finalization
Finalizing the SUNRISE‑FA 2 protocol and FDA confirmation that no extra nonclinical bridging studies are required materially reduces regulatory and timeline uncertainty. Combined with commercial‑scale drug product on hand and an accelerated approval path, this structurally shortens time to potential approval and planning.
Read all positive factors
Lexeo Therapeutics, Inc. (LXEO) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$324.29M
Dividend YieldN/A
Average Volume (3M)1.06M
Price to Earnings (P/E)―
Beta (1Y)2.07
Revenue GrowthN/A
EPS Growth56.00%
CountryUS
Employees59
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-1.45
Shares Outstanding78,521,640
10 Day Avg. Volume1,047,902
30 Day Avg. Volume1,060,633
Financial Highlights & Ratios
PEG Ratio0.13
Price to Book (P/B)2.16
Price to Sales (P/S)0.00
P/FCF Ratio-5.38
Enterprise Value/Market Cap1.01
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-598.23
Enterprise Value/Ebitda-3.83
Forecast
1Y Price Target
$15.75Price Target Upside237.98% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering4
EPS Forecast (FY)-1.16
Revenue Forecast (FY)N/A
Lexeo Therapeutics, Inc. Business Overview & Revenue Model
Company Description
Lexeo Therapeutics, Inc. is a genetic medicine firm currently in the clinical development phase, dedicated to addressing both inherited and acquired medical conditions. Its robust pipeline features several gene therapy candidates. These include LX...
How the Company Makes Money
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Lexeo Therapeutics, Inc. Financial Statement Overview
Summary
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 654.00K | 1.66M |
| Gross Profit | -546.00K | 0.00 | 0.00 | 0.00 | 654.00K | 1.66M |
| EBITDA | -85.19M | -97.68M | -96.19M | -64.35M | -58.04M | -50.61M |
| Net Income | -87.50M | -99.96M | -98.33M | -66.39M | -59.28M | -50.62M |
Balance Sheet | ||||||
| Total Assets | 250.36M | 268.69M | 146.94M | 139.81M | 97.08M | 136.86M |
| Cash, Cash Equivalents and Short-Term Investments | 71.77M | 181.77M | 121.52M | 121.47M | 77.33M | 135.86M |
| Total Debt | 7.37M | 7.89M | 9.92M | 11.64M | 13.48M | 0.00 |
| Total Liabilities | 18.86M | 22.02M | 30.10M | 26.27M | 210.03M | 192.46M |
| Stockholders Equity | 231.50M | 246.67M | 116.84M | 113.53M | -112.95M | -55.60M |
Cash Flow | ||||||
| Free Cash Flow | -98.42M | -98.96M | -81.63M | -59.66M | -55.46M | -44.37M |
| Operating Cash Flow | -97.99M | -98.56M | -81.15M | -59.50M | -54.56M | -44.18M |
| Investing Cash Flow | -78.39M | -90.25M | -94.08M | -165.00K | -901.00K | -188.00K |
| Financing Cash Flow | 219.24M | 216.79M | 88.78M | 103.79M | 189.00K | 150.86M |
Lexeo Therapeutics, Inc. Technical Analysis
Neutral
4.66
Price Trends
4.64
Negative
5.24
Negative
6.84
Negative
Market Momentum
-0.11
Negative
49.48
Neutral
54.07
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LXEO, the sentiment is Neutral. The current price of 4.66 is above the 20-day moving average (MA) of 4.54, above the 50-day MA of 4.64, and below the 200-day MA of 6.84, indicating a neutral trend. The MACD of -0.11 indicates Negative momentum. The RSI at 49.48 is Neutral, neither overbought nor oversold. The STOCH value of 54.07 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for LXEO.
Lexeo Therapeutics, Inc. Risk Analysis
Lexeo Therapeutics, Inc. disclosed 75 risk factors in its most recent earnings report. Lexeo Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Lexeo Therapeutics, Inc. Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
55 Neutral | $396.83M | -1.82 | -137.39% | ― | ― | -39.31% | |
55 Neutral | $341.62M | -8.93 | -77.09% | ― | ― | -9.22% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
46 Neutral | $324.29M | -2.85 | -47.48% | ― | ― | 56.00% | |
46 Neutral | $222.96M | -1.66 | -59.27% | ― | -100.00% | -62.96% | |
45 Neutral | $19.70M | -1.32 | -64.17% | ― | -100.00% | 94.65% | |
44 Neutral | $402.29M | -10.55 | -34.82% | ― | ― | 41.21% |
* Healthcare Sector Average
LXEO
Lexeo Therapeutics, Inc.
4.55
0.10
2.25%
TVRD
Tvardi Therapeutics
1.85
-21.27
-92.00%
LRMR
Larimar Therapeutics
4.20
0.54
14.75%
CAPR
Capricor Therapeutics
4.18
-3.89
-48.20%
BNTC
Benitec Biopharma
13.13
1.38
11.74%
DMAC
Diamedica Therapeutics
6.77
1.95
40.46%
Lexeo Therapeutics, Inc. Corporate Events
Executive/Board ChangesShareholder Meetings
Lexeo Shareholders Reelect Directors, Ratify KPMG Auditor
Positive
Jun 29, 2026
Lexeo Therapeutics, Inc. held its 2026 Annual Meeting of Stockholders virtually on June 25, 2026, where shareholders voted on key corporate governance matters, signaling continued engagement with the company’s strategic direction. Stockholde...
Business Operations and StrategyProduct-Related Announcements
Lexeo Advances Pivotal LX2006 Trial for FA Cardiomyopathy
Positive
Jun 15, 2026
On June 15, 2026, Lexeo Therapeutics announced it has finalized the pivotal SUNRISE-FA 2 trial protocol and statistical analysis plan for LX2006, its gene therapy candidate for Friedreich ataxia cardiomyopathy, aiming to support a future Biologics...
Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresProduct-Related AnnouncementsRegulatory Filings and Compliance
Lexeo Highlights Q1 Progress Advancing Cardiac Gene Therapies
Positive
May 11, 2026
On May 11, 2026, Lexeo Therapeutics reported first-quarter 2026 results and operational progress, highlighting advancement of its LX2006 and LX2020 gene therapy programs and strengthening of its leadership. The company submitted the SUNRISE-FA2 pi...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.