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TYK Medicines, Inc. Class H (HK:2410)
:2410
Hong Kong Market

TYK Medicines, Inc. Class H (2410) AI Stock Analysis

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HK:2410

TYK Medicines, Inc. Class H

(2410)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
HK$13.50
▲(4.41% Upside)
Action:ReiteratedDate:01/08/26
The score is primarily held down by very weak financial performance: persistent large losses and sustained, worsening cash burn with minimal/volatile revenue. Technical indicators are mixed but slightly improved in the near term (above 20D/50D with neutral-to-positive RSI), providing only limited support. Valuation impact is neutral due to missing P/E and dividend yield data.
Positive Factors
Improved 2024 Capitalization
Positive shareholders' equity and moderate leverage in 2024 materially improve solvency versus prior years, giving the company more flexibility to fund development programs and survive funding gaps. This stronger capitalization reduces near-term default risk and supports longer-term strategic options.
Substantive Asset Base
A nearly ¥916m asset base provides tangible resources—cash, IP or working assets—that can be deployed for R&D, partnerships, or manufacturing scale. A larger asset cushion supports strategic investments and gives management optionality to pursue long-term growth initiatives or secure financing on better terms.
Positive Gross Profit in 2024
Recording positive gross profit indicates the core product or manufacturing economics can cover direct costs. That suggests potential for margin expansion if operating expenses and R&D are controlled and revenue scales, making sustainable profitability achievable at higher volumes.
Negative Factors
Persistent Negative Operating Cash Flow
Consistent, worsening operating cash burn means the business consumes substantial cash to operate, forcing reliance on external funding. Over months this pressures liquidity, risks dilutive capital raises, and limits the firm's ability to fund R&D or commercialization organically without altering strategy.
Minimal and Volatile Revenue
Highly inconsistent, minimal revenues indicate weak product commercialization and uncertain market traction. Without predictable revenue streams, scaling operations and achieving operating leverage is difficult, increasing dependence on financing and making long-term margin improvement uncertain.
Large and Persistent Net Losses
Sustained substantial net losses erode retained capital and create ongoing pressure to raise funds, diluting shareholders and constraining strategic choices. Long-term recovery requires structural shifts to revenues or cost base; absent that, profitability and returns to investors remain highly uncertain.

TYK Medicines, Inc. Class H (2410) vs. iShares MSCI Hong Kong ETF (EWH)

TYK Medicines, Inc. Class H Business Overview & Revenue Model

Company DescriptionTYK Medicines, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, acquisition, development, and commercialization of therapies to address unmet medical needs in cancer treatment. Its lead product candidate is TY-9591, a third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor for the treatment of brain metastases from non-small cell lung cancer (NSCLC) with EGFR mutations, and in locally advanced or metastatic NSCLC with EGFR L858R mutation. The company also develops TY-302, an oral cyclin-dependent kinase (CDK) 4/6 inhibitor to treat solid tumors, including breast cancer and prostate cancer; TY-2136b, an oral ROS proto-oncogene 1/neurotrophic tyrosine receptor kinase inhibitor for the treatment of solid tumors; TY-2699a, a selective CDK7 inhibitor for the treatment of advanced/metastatic solid tumors; and TY-0540, a selective CDK2/4/6 inhibitor to treat advanced/metastatic solid tumors. In addition, it develops TY-4028, an oral exon 20 insertion-TKI targeting locally advanced or metastatic NSCLC with EGFR exon 20 or HER2 exon 20 insertions; TY-1091, a potent and selective rearranged during transfection proto-oncogene (RET) inhibitor for the treatment of advanced NSCLC with RET gene fusion, advanced medullary thyroid cancer with RET gene mutation, and other advanced solid tumors with RET gene alterations; TY-1054, an oral yes associated protein-transcriptional enhanced associate domain inhibitor for cancer treatment; TY-1210, a selective CDK2 inhibitor to treat solid tumors; TY-0609, a selective CDK4 inhibitor for the treatment of cancer; and TY-3200, an EGFR degrader. The company was incorporated in 2017 and is headquartered in Huzhou, China.

TYK Medicines, Inc. Class H Financial Statement Overview

Summary
Overall fundamentals are very weak: minimal/volatile revenue, large and persistent net losses, and consistently negative operating and free cash flow (2024 operating cash flow ~-308.3m; free cash flow ~-381.9m). The main offset is an improved 2024 balance sheet with positive equity (~469.1m) and moderate leverage (debt-to-equity ~0.38), but ongoing cash burn indicates continued reliance on external funding.
Income Statement
14
Very Negative
The income statement shows a business still in a heavy loss-making phase. Revenue is very small and inconsistent (2024: 107k vs. 2022: 44.2m; 2023 shows 0), and profitability is deeply negative with large operating losses and a sizable net loss in each period (2024 net loss: ~387.0m; 2022: ~311.0m). While 2024 reports a positive gross profit, the operating cost base overwhelms it, resulting in extremely weak margins and limited evidence of improving earnings trajectory.
Balance Sheet
45
Neutral
Balance sheet quality is mixed. On the positive side, 2024 shows positive shareholders’ equity (~469.1m) and moderate leverage (debt-to-equity ~0.38) with total assets of ~915.7m, suggesting improved capitalization versus prior years. Offsetting this, earlier periods show negative equity (2022–2023), and returns to shareholders are poor given persistent net losses (2024 return on equity is strongly negative). Overall, the balance sheet looks improved in 2024 but the history of weak equity and ongoing losses remains a key risk.
Cash Flow
18
Very Negative
Cash generation is weak, with operating cash flow negative in all periods (2024: ~-308.3m; 2023: ~-200.9m; 2022: ~-220.1m) and free cash flow also consistently negative (2024: ~-381.9m). 2024 cash burn worsened versus 2023, indicating rising funding needs. Free cash flow is negative but roughly tracks the scale of net losses, suggesting losses are translating into real cash outflows rather than being primarily non-cash accounting items.
BreakdownTTMDec 2024Dec 2023Dec 2022
Income Statement
Total Revenue0.00107.00K0.0044.24M
Gross Profit0.0014.00K0.0020.04M
EBITDA-199.38M-346.03M-346.80M-292.22M
Net Income-219.05M-386.95M-382.43M-310.99M
Balance Sheet
Total Assets529.30M915.69M573.14M558.36M
Cash, Cash Equivalents and Short-Term Investments158.31M435.46M192.83M243.49M
Total Debt120.72M176.85M1.33B82.33M
Total Liabilities1.57B443.13M1.45B1.06B
Stockholders Equity-1.05B469.09M-973.82M-505.94M
Cash Flow
Free Cash Flow-154.55M-381.87M-278.20M-308.23M
Operating Cash Flow-136.28M-308.25M-200.94M-220.05M
Investing Cash Flow-120.14M-135.86M73.01M-158.16M
Financing Cash Flow114.65M632.08M224.00M351.14M

TYK Medicines, Inc. Class H Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
73
Outperform
HK$6.86B2.2110.84%5.80%-20.64%-25.39%
57
Neutral
HK$8.38B135.646.73%23.37%
55
Neutral
HK$6.34B-1.79-9.73%2.38%-8.56%-403.12%
54
Neutral
HK$15.79B-22.61-12.74%-76.58%-4.90%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
HK$10.80B5.8918.28%59.70%239.97%
46
Neutral
HK$4.07B153.33%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:2410
TYK Medicines, Inc. Class H
10.84
-15.76
-59.25%
HK:1672
Ascletis Pharma, Inc.
14.88
7.06
90.28%
HK:1951
Jinxin Fertility Group Ltd.
2.31
-1.02
-30.63%
HK:2142
HBM Holdings Ltd.
12.21
3.89
46.75%
HK:2256
Abbisko Cayman Limited
12.32
4.37
54.97%
HK:2877
China Shineway Pharmaceutical Group Limited
9.08
0.77
9.27%

TYK Medicines, Inc. Class H Corporate Events

TYK Medicines Completes Full H-Share Conversion to Boost Market Liquidity
Mar 4, 2026

TYK Medicines, Inc. has completed the conversion of 4,608,000 unlisted shares into H shares, with trading of these converted H shares on the Hong Kong Stock Exchange set to begin on March 5, 2026. Following the conversion, all 380,065,818 issued shares of the company are now H shares, simplifying the capital structure and potentially improving liquidity for existing and prospective investors.

The company’s H shares now represent 100% of its share capital, compared with 98.79% before the transaction, eliminating the previous portion of unlisted shares. The board has cautioned shareholders and potential investors to exercise care when dealing in the company’s H shares, underscoring that the change may influence trading dynamics and market perceptions of the stock.

The most recent analyst rating on (HK:2410) stock is a Hold with a HK$13.50 price target. To see the full list of analyst forecasts on TYK Medicines, Inc. Class H stock, see the HK:2410 Stock Forecast page.

TYK Medicines Dilutes Stake in TYK Bio via RMB83.5 Million Capital Injection
Feb 27, 2026

TYK Medicines, Inc. has agreed to a capital increase in its subsidiary TYK Bio, under which new and existing investors will inject about RMB83.5 million, raising TYK Bio’s registered capital from RMB14.0 million to roughly RMB20.49 million and diluting the parent’s stake from 57.14% to 39.03%. As a result, TYK Bio will cease to be a subsidiary of TYK Medicines, although the funds will be ring‑fenced for operating purposes and restricted from debt repayment to shareholders, non-core expenditures, financial investments, or equity repurchases without subscriber consent.

Because a fund partly owned by chairman and CEO Dr. Wu Yusheng is among the new investors, the deal is treated as a connected transaction under Hong Kong listing rules, but the size of the transaction means it only triggers reporting and announcement obligations, without requiring a shareholder circular or independent shareholder approval. The move provides fresh operating capital for TYK Bio while reducing TYK Medicines’ direct control, potentially shifting the unit’s governance structure and risk profile for minority investors within the framework of the exchange’s related-party transaction safeguards.

The most recent analyst rating on (HK:2410) stock is a Hold with a HK$13.50 price target. To see the full list of analyst forecasts on TYK Medicines, Inc. Class H stock, see the HK:2410 Stock Forecast page.

TYK Medicines Wins Approval for Full H-Share Circulation in Hong Kong
Feb 12, 2026

TYK Medicines, Inc., a PRC-incorporated joint stock company listed in Hong Kong, operates through H shares on the Stock Exchange of Hong Kong. Its share capital has comprised both H shares and unlisted shares, enabling participation from both public investors and private venture capital stakeholders.

The company has received approval from the Hong Kong Stock Exchange to list 4,608,000 converted H shares, representing previously unlisted shares held by a single shareholder. Following this conversion, all 380,065,818 shares of the company will be H shares, simplifying the capital structure and completing full circulation of H shares, which may enhance liquidity and accessibility for investors.

The most recent analyst rating on (HK:2410) stock is a Hold with a HK$13.50 price target. To see the full list of analyst forecasts on TYK Medicines, Inc. Class H stock, see the HK:2410 Stock Forecast page.

TYK Medicines’ Lung Cancer Drug Asandeutertinib NDA Accepted by China’s NMPA
Feb 6, 2026

TYK Medicines has announced that China’s National Medical Products Administration has accepted its New Drug Application for Asandeutertinib (TY-9591), a deuterated analog of osimertinib intended as a first-line treatment for adults with locally advanced or metastatic EGFR-mutated non-small cell lung cancer with central nervous system metastases. Backed by Phase I and II clinical data indicating superior intracranial and systemic response rates and clinical benefit compared with existing therapy osimertinib, the filing underscores TYK Medicines’ ambition to strengthen its position in targeted lung cancer treatments, although the company cautions that acceptance of the application is only an administrative step and approval is not guaranteed, highlighting the inherent risks and uncertainties in pharmaceutical development for investors and other stakeholders.

The most recent analyst rating on (HK:2410) stock is a Hold with a HK$13.50 price target. To see the full list of analyst forecasts on TYK Medicines, Inc. Class H stock, see the HK:2410 Stock Forecast page.

TYK Medicines’ Lung Cancer Drug Asandeutertinib Granted Priority Review in China
Jan 29, 2026

TYK Medicines announced that its investigational Class 1 new drug Asandeutertinib (TY-9591), a deuterated analog of osimertinib, has been accepted by China’s Center for Drug Evaluation for priority review for use as a first-line treatment for adult patients with locally advanced or metastatic EGFR-mutated non-small cell lung cancer (NSCLC) with central nervous system metastases. The decision reflects the drug’s potential to address a significant unmet clinical need in brain metastases from NSCLC, an area where no third-generation EGFR-TKIs have yet been formally approved worldwide for this specific indication and where existing therapies rely on limited retrospective data, with TY-9591’s Phase I and II studies showing promising intracranial and systemic efficacy that could strengthen TYK Medicines’ position in the oncology drug market if ultimately approved.

The most recent analyst rating on (HK:2410) stock is a Hold with a HK$13.50 price target. To see the full list of analyst forecasts on TYK Medicines, Inc. Class H stock, see the HK:2410 Stock Forecast page.

TYK Medicines Wins CSRC Nod for Conversion of 4.6 Million Unlisted Shares into H Shares
Jan 23, 2026

TYK Medicines, Inc. has received a filing notice from the China Securities Regulatory Commission approving its H share full circulation application, enabling the conversion of 4,608,000 unlisted domestic shares held by one shareholder into the same number of H shares. Once the conversion is implemented and listing approval is granted by the Hong Kong Stock Exchange, these newly converted H shares will be tradable on the Main Board, potentially enhancing the company’s share liquidity and broadening its investor base, though the detailed implementation plan is still being finalized and remains subject to additional regulatory procedures.

The most recent analyst rating on (HK:2410) stock is a Hold with a HK$13.50 price target. To see the full list of analyst forecasts on TYK Medicines, Inc. Class H stock, see the HK:2410 Stock Forecast page.

TYK Medicines Secures Zhejiang Drug Manufacturing License to Support Cancer Drug Commercialisation
Jan 23, 2026

TYK Medicines, Inc. announced it has been granted a Drug Manufacturing License by the Drug Administration of Zhejiang Province, authorising production via trustee manufacturer Asymchem Life Science (Tianjin) Co., Ltd. through January 2031. The company expects the license to underpin long-term capacity and market expansion and to lay a foundation for subsequent commercial production of its cancer therapies, potentially accelerating the delivery of new treatment options to patients, though it cautions there is no assurance its products will ultimately reach the market.

The most recent analyst rating on (HK:2410) stock is a Hold with a HK$13.50 price target. To see the full list of analyst forecasts on TYK Medicines, Inc. Class H stock, see the HK:2410 Stock Forecast page.

TYK Medicines’ Lung Cancer Drug Candidate Proposed for Priority Review Amid Share Volatility
Jan 7, 2026

TYK Medicines said its investigational Class 1 new drug Asandeutertinib (TY-9591) has been proposed by China’s Center for Drug Evaluation to be included in the national priority review list for first-line treatment of adults with locally advanced or metastatic non-small cell lung cancer, including central nervous system metastases, carrying specific EGFR mutations, underscoring the potential strategic importance of this candidate in the competitive lung cancer therapy market. The board also addressed recent unusual share price and trading volume movements, stating it is unaware of any undisclosed information behind the volatility, and confirmed that the group’s business operations remain normal and stable with core projects progressing as planned, while cautioning investors that there is no assurance the drug will ultimately be successfully developed and marketed.

The most recent analyst rating on (HK:2410) stock is a Hold with a HK$12.50 price target. To see the full list of analyst forecasts on TYK Medicines, Inc. Class H stock, see the HK:2410 Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 08, 2026