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Abbisko Cayman Limited (HK:2256)
:2256
Hong Kong Market

Abbisko Cayman Limited (2256) AI Stock Analysis

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HK

Abbisko Cayman Limited

(2256)

Rating:66Neutral
Price Target:
HK$11.00
▲(7.42%Upside)
The strong momentum in the stock price is the most significant factor driving the score, supported by notable improvements in financial performance. However, the high P/E ratio suggests overvaluation, which poses a risk to potential investors. The absence of earnings call data and corporate events maintains focus on the current financials and technical indicators.
Positive Factors
Clinical Trial Results
The MANEUVER trial demonstrated a 54% ORR in patients treated with pimicotinib compared to 3.2% for patients treated with placebo.
Financial Performance
The analyst's price target for Abbisko Therapeutics stock has been raised from HK$16.00 to HK$18.00.
Regulatory Submission
The company expects to submit an NDA for pimicotinib in Tenosynovial Giant Cell Tumor to the Chinese NMPDA and to the US FDA, demonstrating best-in-class efficacy in TGCT.
Negative Factors
Market Competition
Merck KGaA exclusively licensed commercialization rights for pimicotinib in several regions, with substantial potential payments and royalties.
Regulatory Approval Process
The company plans to start the registrational irpagratinib trial that will evaluate monotherapy in FGFR19+ hepatocellular carcinoma in China.

Abbisko Cayman Limited (2256) vs. iShares MSCI Hong Kong ETF (EWH)

Abbisko Cayman Limited Business Overview & Revenue Model

Company DescriptionAbbisko Cayman Limited, a clinical-stage biopharmaceutical company, discovers and develops small molecule oncology therapies in the People's Republic of China. Its product candidates are primarily small molecules that focus on small molecule precision oncology and small molecule immuno-oncology therapeutic areas. The company's primary product candidates are ABSK011, a small molecule inhibitor of fibroblast growth factor receptor 4 for the treatment of advanced hepatocellular carcinoma with hyper-activation of FGF19/FGFR4 signaling; and ABSK091, a molecularly targeted product candidate for the treatment of multiple solid tumors, including urothelial cancer, gastric cancer, cholangiocarcinoma, and lung cancer. It also has other pipeline product candidates. The company was founded in 2016 and is headquartered in Shanghai, the People's Republic of China.
How the Company Makes MoneyAbbisko Cayman Limited makes money through the development and commercialization of its proprietary drug candidates. The company's revenue model is primarily based on licensing agreements, collaborations, and partnerships with other pharmaceutical companies. These partnerships often involve milestone payments, royalties, and co-development opportunities that provide financial support for ongoing research and development. Additionally, Abbisko may generate revenue from potential future product sales upon successful commercialization of its drug candidates. The company's strategic collaborations with industry leaders enhance its capabilities in drug development and expand its market reach, contributing to its revenue potential.

Abbisko Cayman Limited Financial Statement Overview

Summary
Abbisko Cayman Limited has shown significant revenue growth and improved net income in the latest year, indicating potential for future profitability. The balance sheet is strong with low debt and high equity, but the company must continue to manage its cash flows effectively to ensure long-term sustainability. Despite improvements, sustained effort is needed for continuous progress.
Income Statement
65
Positive
Abbisko Cayman Limited has shown a substantial increase in revenue in 2024 compared to 2023. The gross profit margin is 100% for both years, indicating all revenue contributes directly to profit before expenses. However, despite revenue growth, the company has struggled with profitability, as reflected by negative EBIT and EBITDA margins in recent years, although net income turned positive in 2024, indicating some improvement.
Balance Sheet
72
Positive
The company maintains a strong equity position with a very low debt-to-equity ratio, indicating limited reliance on debt financing. The equity ratio is high, suggesting strong financial stability. However, the return on equity is low due to prior years of negative net income, although there was a positive turn in 2024 which indicates some improvement in leveraging equity for profits.
Cash Flow
58
Neutral
Operating cash flow remains negative, indicating that the business is not generating sufficient cash from operations. However, free cash flow has improved in 2024 compared to 2023, suggesting better cash management. The company has also reduced its capital expenditures, which might have helped in improving free cash flow.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
503.99M19.06M0.0022.68M0.00
Gross Profit
503.99M19.06M0.0022.68M0.00
EBIT
-21.59M-511.08M-492.92M-1.81B-706.47M
EBITDA
-15.28M-410.99M-492.62M-1.80B-696.98M
Net Income Common Stockholders
28.30M-431.58M-498.29M-1.81B-706.81M
Balance SheetCash, Cash Equivalents and Short-Term Investments
1.96B2.01B2.35B2.55B617.77M
Total Assets
2.11B2.12B2.49B2.65B665.97M
Total Debt
24.29M35.72M45.58M53.80M4.31M
Net Debt
-265.25M-1.94B-2.21B-2.49B-613.47M
Total Liabilities
148.71M134.28M143.16M118.48M1.77B
Stockholders Equity
1.96B1.98B2.35B2.54B-1.10B
Cash FlowFree Cash Flow
-20.32M-456.98M-366.64M-182.08M-121.60M
Operating Cash Flow
-12.92M-444.73M-343.90M-169.74M-117.56M
Investing Cash Flow
-196.50M378.52M-216.57M-1.46B-11.25M
Financing Cash Flow
-80.86M-16.11M-20.81M2.10B505.89M

Abbisko Cayman Limited Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.24
Price Trends
50DMA
8.21
Positive
100DMA
7.23
Positive
200DMA
5.60
Positive
Market Momentum
MACD
0.61
Negative
RSI
67.72
Neutral
STOCH
79.48
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:2256, the sentiment is Positive. The current price of 10.24 is above the 20-day moving average (MA) of 9.30, above the 50-day MA of 8.21, and above the 200-day MA of 5.60, indicating a bullish trend. The MACD of 0.61 indicates Negative momentum. The RSI at 67.72 is Neutral, neither overbought nor oversold. The STOCH value of 79.48 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for HK:2256.

Abbisko Cayman Limited Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
HK$6.96B174.451.43%2433.62%
54
Neutral
$5.38B3.27-45.10%3.30%16.81%0.02%
€4.19B-32.29%
DE4WO
€476.99M-10.43%
62
Neutral
HK$3.78B21.214.47%-9.75%
55
Neutral
HK$85.68B-8.98%-54.66%-123.11%
49
Neutral
HK$2.46B-2.19%5.32%89.43%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:2256
Abbisko Cayman Limited
10.24
7.20
236.84%
DE:1ZLB
Zai Lab Ltd
3.56
1.88
111.90%
DE:4WO
Peijia Medical Ltd.
0.70
0.24
52.17%
HK:9926
Akeso, Inc.
95.85
55.05
134.93%
HK:1873
Viva Biotech Holdings
1.79
1.23
219.64%
HK:2160
MicroPort CardioFlow Medtech Corp.
1.02
0.10
10.87%

Abbisko Cayman Limited Corporate Events

Abbisko Cayman Limited’s CEO Increases Stake Amid Share Buyback Plan
Jun 12, 2025

Abbisko Cayman Limited announced an increase in shareholding by its founder and CEO, Dr. Xu Yao-Chang, who purchased 17,000 ordinary shares, bringing his total shareholding to approximately 11.77% of the company. This move reflects Dr. Xu’s confidence in the company’s growth prospects. Additionally, the company has been executing a share repurchase plan, buying back 8,695,000 shares to date, which the board believes will enhance shareholder value as the current trading price undervalues the company’s intrinsic worth.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko Cayman Limited Addresses Criticism of Director
Jun 12, 2025

Abbisko Cayman Limited announced that Mr. Sun Hongbin, an independent non-executive director of the company, has been publicly criticized by the Hong Kong Stock Exchange for his conduct during his tenure at New Century Healthcare. The criticism pertains to his failure to ensure adequate steps were taken to collect receivables and safeguard interests at New Century Healthcare. Despite this, Abbisko’s board has assessed the situation and believes it will not adversely impact the company’s operations or business.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko Therapeutics’ Pimicotinib NDA Accepted by China NMPA for TGCT Treatment
Jun 10, 2025

Abbisko Cayman Limited announced that its subsidiary, Abbisko Therapeutics, has received acceptance from the China National Medical Products Administration (NMPA) for the New Drug Application (NDA) of pimicotinib, a CSF-1R inhibitor, for treating Tenosynovial Giant Cell Tumor (TGCT). This marks a significant milestone as pimicotinib is the first internally discovered drug by Abbisko to enter the NDA process, showing promising clinical efficacy and safety. The drug has received Priority Review and Breakthrough Therapy Designation in China, and similar recognitions in the US and EU, indicating its potential impact on the market and stakeholders. Abbisko has partnered with Merck for the global commercialization of pimicotinib, which demonstrated significant improvements in clinical trials presented at the 2025 ASCO Annual Meeting.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko Secures $85 Million from Merck for Pimicotinib Global Rights
May 29, 2025

Abbisko Therapeutics has received an $85 million global commercialization option fee from Merck for pimicotinib (ABSK021), a CSF-1R inhibitor, under a licensing agreement. This fee will be recognized as revenue in 2025. The agreement allows Merck to commercialize pimicotinib worldwide, with Abbisko eligible for up to $605.5 million in milestone payments and royalties. Pimicotinib has shown promising results in treating tenosynovial giant cell tumor (TGCT) and has received multiple regulatory designations, highlighting its potential impact in the oncology market.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko Therapeutics’ Irpagratinib Receives Breakthrough Therapy Designation for HCC Treatment
May 26, 2025

Abbisko Therapeutics has announced that its small molecule FGFR4 inhibitor, irpagratinib (ABSK011), has received Breakthrough Therapy Designation from the China National Medical Products Administration for treating Hepatocellular Carcinoma (HCC). This designation is based on promising Phase I clinical trial data and aims to expedite the drug’s approval process, offering new hope for patients with advanced HCC, particularly those with FGF19 overexpression. The company is also conducting a pivotal registrational clinical study and exploring combination therapies to enhance treatment efficacy.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko Therapeutics to Present Phase 3 Pimicotinib Results at 2025 ASCO Meeting
May 23, 2025

Abbisko Cayman Limited announced that its subsidiary, Abbisko Therapeutics, will present the results of its phase 3 study on pimicotinib at the 2025 ASCO Annual Meeting. This presentation will cover the efficacy, safety, and clinical outcomes of pimicotinib in treating TGCT, potentially impacting Abbisko’s market positioning and stakeholder interests, especially given the drug’s breakthrough therapy designations.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko’s Pimicotinib Gains Priority Review in China for TGCT
May 20, 2025

Abbisko Therapeutics announced that its CSF-1R inhibitor, pimicotinib (ABSK021), has been granted Priority Review status by the China National Medical Products Administration for treating Tenosynovial Giant Cell Tumor (TGCT). This designation is expected to expedite the review process, potentially allowing quicker access for patients. Pimicotinib has previously received Breakthrough Therapy Designation from both the China NMPA and the US FDA, and Priority Medicine designation from the European Medicines Agency. The drug has shown promising results in clinical trials, meeting all primary and secondary endpoints with a significant objective response rate.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko Cayman Limited Announces 2025 AGM Agenda
May 16, 2025

Abbisko Cayman Limited has announced its upcoming Annual General Meeting (AGM) scheduled for June 18, 2025, in Shanghai. Key agenda items include the approval of the company’s audited financial statements for 2024, re-election of directors, and authorization for the board to fix directors’ remuneration. Additionally, the company seeks approval to re-appoint Ernst & Young as auditors and to authorize the board to manage share allotments, potentially impacting the company’s capital structure and shareholder value.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko Therapeutics to Present Promising Phase 2 Study Results at 2025 ESMO GI Congress
May 13, 2025

Abbisko Cayman Limited announced that its subsidiary, Abbisko Therapeutics, will present updated results from a Phase 2 study of irpagratinib in combination with atezolizumab for advanced hepatocellular carcinoma at the 2025 ESMO GI Congress. The study highlights the combination’s favorable safety and promising anti-tumor activity, particularly in FGF19+ HCC patients, indicating potential advancements in treatment options for this cancer type.

The most recent analyst rating on (HK:2256) stock is a Buy with a HK$18.00 price target. To see the full list of analyst forecasts on Abbisko Cayman Limited stock, see the HK:2256 Stock Forecast page.

Abbisko’s CEO Increases Stake Amid Share Repurchase Plan
May 6, 2025

Abbisko Cayman Limited announced an increase in shareholding by its founder and CEO, Dr. Xu Yao-Chang, who purchased 30,000 shares, reflecting his confidence in the company’s growth prospects. Additionally, the company has repurchased 4,798,000 shares under its Share Repurchase Plan, indicating that the current trading price undervalues its business potential.

Abbisko Therapeutics Unveils Promising Pre-Clinical Cancer Research at AACR 2025
Apr 28, 2025

Abbisko Therapeutics announced the presentation of four late-breaking pre-clinical research results at the 2025 American Association for Cancer Research conference. The studies focused on ABSK112, ABSK131, and ABK-KRAS-1 inhibitors, highlighting their potential in treating cancer and addressing resistance mechanisms. These findings could significantly impact Abbisko’s market positioning by advancing their therapeutic pipeline and offering new treatment strategies for cancer patients.

Abbisko Cayman Limited Updates Post-IPO Schemes with Treasury Shares
Apr 17, 2025

Abbisko Cayman Limited announced amendments to its Post-IPO RSU and Share Option Schemes, allowing the use of treasury shares to satisfy grants and exercises. This aligns with recent changes in the Listing Rules, providing the company with greater flexibility in managing these schemes and potentially enhancing its operational efficiency.

Merck Exercises Global Option for Abbisko’s Pimicotinib
Apr 1, 2025

Abbisko Therapeutics announced that Merck has exercised its global commercialization option for pimicotinib, a CSF-1R inhibitor, under their licensing agreement. This move, involving an option exercise fee of USD85 million, signifies a deepening collaboration and confidence in pimicotinib’s potential, especially after its successful Phase III trial results for treating tenosynovial giant cell tumor. The agreement could lead to Abbisko receiving up to USD605.5 million in payments, highlighting a significant impact on the company’s financial and industry positioning.

Abbisko Therapeutics Receives IND Clearance for Innovative Achondroplasia Treatment
Mar 26, 2025

Abbisko Therapeutics announced that the Center for Drug Evaluation of the China National Medical Products Administration has cleared the IND application for ABSK061, a highly selective FGFR2/3 inhibitor, for treating children with achondroplasia. This development marks a significant step for Abbisko as ABSK061 is the first FGFR2/3 inhibitor to enter clinical trials globally, aiming to provide a wider therapeutic window and improved clinical efficacy compared to first-generation inhibitors, potentially impacting the treatment landscape for achondroplasia, a rare disorder with no specific treatments in China.

Abbisko and Allist Collaborate on NSCLC Treatment
Mar 24, 2025

Abbisko Cayman Limited announced a cooperation agreement between its subsidiary, Abbisko Therapeutics, and Shanghai Allist Pharmaceuticals to explore the combination of Abbisko’s ABSK043 and Allist’s glecirasib for treating non-small cell lung cancer (NSCLC) patients with KRAS-G12C mutation. This collaboration aims to leverage the promising results of ABSK043, which has shown favorable safety and anti-tumor activity in early trials, potentially enhancing Abbisko’s position in the oncology market and offering new hope for NSCLC treatment.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.