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Genscript Biotech (HK:1548)
:1548

Genscript Biotech (1548) AI Stock Analysis

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HK:1548

Genscript Biotech

(1548)

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Neutral 60 (OpenAI - 4o)
Rating:60Neutral
Price Target:
HK$14.00
▲(3.70% Upside)
Genscript Biotech's overall score reflects strong revenue growth and positive earnings call highlights, but is tempered by challenges in profitability, bearish technical indicators, and valuation concerns. The company's future success hinges on improving operational efficiency and achieving sustainable profitability.
Positive Factors
Revenue Growth
Strong revenue growth across all segments indicates robust demand and successful execution of business strategies, supporting long-term expansion.
Strong Cash Position
A strong cash position enhances financial flexibility, enabling strategic investments in R&D and expansion, crucial for sustaining growth.
ESG Achievements
Strong ESG ratings reflect commitment to sustainability and governance, enhancing reputation and potentially attracting more investors.
Negative Factors
Net Loss Due to Legend Biotech
Ongoing losses from Legend Biotech strain overall profitability, potentially impacting financial stability and investor confidence.
Temporary Gross Margin Impact
Temporary margin impacts could signal challenges in cost management, affecting short-term profitability and requiring strategic adjustments.
ProBio's Capacity Challenges
Capacity challenges in ProBio may hinder service delivery and margin recovery, affecting growth prospects if not addressed promptly.

Genscript Biotech (1548) vs. iShares MSCI Hong Kong ETF (EWH)

Genscript Biotech Business Overview & Revenue Model

Company DescriptionGenscript Biotech Corporation, an investment holding company, engages in the manufacture and sale of life science research products and services in North America, Europe, the People's Republic of China, Japan, the other Asia Pacific regions, and internationally. It operates through four segments: Life Science Services and Products, Biologics Development Services, Industrial Synthetic Biology Products, and Cell Therapy. The Life Science Services and Products segment provides research services in various categories, including gene synthesis and molecular cloning, oligonucleotide synthesis, protein engineering, peptide synthesis, antibody development, molecular diagnostics tools, and genome editing materials for use in basic biology studies, pharmaceutical and drug discovery, disease diagnostics and vaccine, agriculture, environmental studies, and food industry. The Biologics Development Services segment offers various services, such as antibody drug discovery, antibody drug pre-clinical and clinical development, plasmid and virus pre-clinical development, and plasmid and virus clinical development for therapeutic antibodies, as well as gene and cell therapy development and biologics discovery and development services for pharmaceutical, biotech, government, and academic customers. The Industrial Synthetic Biology Products segment constructs non-pathogenic microbial strains; and develops and produces industrial enzymes for food processing, feed, pharmaceutical, and chemical industries. The Cell Therapy segment discovers and develops chimeric antigen receptor T-cell therapies for the treatment of liquid and solid tumors. Genscript Biotech Corporation was founded in 2002 and is headquartered in Nanjing, the People's Republic of China.
How the Company Makes MoneyGenscript Biotech generates revenue primarily through its diverse offerings in gene synthesis, protein production, and antibody services. The company operates on a B2B model, where it serves a wide array of clients including academic institutions, pharmaceutical companies, and biotechnology firms. Key revenue streams include custom gene synthesis, which involves creating specific DNA sequences for clients; peptide synthesis, where customized peptides are produced for research and therapeutic applications; and contract research services, which include various laboratory services for drug discovery and development. Additionally, Genscript benefits from strategic partnerships with other biotech firms and research institutions, enhancing its market reach and service offerings. The company's continuous investment in R&D and technological advancements also supports its revenue growth by enabling the introduction of new products and services to meet evolving market demands.

Genscript Biotech Earnings Call Summary

Earnings Call Date:Aug 17, 2025
(Q2-2025)
|
Next Earnings Date:Mar 27, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant revenue growth across all segments, strong performance of Legend Biotech's CAR-T product, and a robust cash position. However, the Group faced challenges with net losses due to Legend Biotech, temporary impacts on gross margins, and capacity issues in ProBio. Despite these challenges, the positive achievements and growth outweigh the difficulties.
Q2-2025 Updates
Positive Updates
Record Revenue Growth
The Group's revenue increased by 81.9% year-over-year to approximately USD 519 million. All three segments achieved growth, with GenScript Life Science growing by 11.3%, ProBio by 511%, and Bestzyme by 8.4%.
Successful CAR-T Product Performance
Legend Biotech's CARVYKTI, a best-in-class CAR-T product, treated over 7,500 patients, with net trade sales growing 136% to USD 439 million in the second quarter.
Strong Cash Position
The Group's cash position stood at USD 970 million, supporting global expansion, R&D progress, and capacity ramp-up.
ESG Achievements
Significant breakthroughs in global ESG ratings, including a silver medal from EcoVadis, an MSCI ESG rating upgrade to AA, and inclusion in the FTSE4Good Index series.
ProBio's Return to Growth
ProBio achieved a return to revenue growth after two challenging years, driven by platform innovation and quality system enhancement.
Innovation in Life Science
The Life Science segment reported a 52% growth in services revenue, with advancements in TurboCHO high-throughput platform and CRISPR solutions.
Negative Updates
Net Loss Due to Legend Biotech
The Group's net loss was approximately USD 24.5 million, significantly impacted by Legend Biotech's current period loss and the amortization impact of a USD 3.2 billion variation increase when it was deconsolidated in 2024.
Temporary Gross Margin Impact
The gross profit margin was temporarily impacted by a change in product mix and global capacity expansion.
ProBio's Capacity Challenges
ProBio faced challenges with capacity ramp-up, which impacted the fee-for-service margin.
Bestzyme's Slow First Half
Bestzyme's growth was slower in the first half due to the holiday season in China, but a strong recovery is expected in the second half.
Company Guidance
During the 2025 interim results conference call, GenScript provided detailed guidance on their financial and operational performance for the first half of the year and projections for the second half. The company reported an impressive 82% year-over-year revenue growth, with the adjusted profit from continuing operations significantly increasing to approximately USD 180 million. Key highlights included the GenScript Life Science business achieving an 11.3% revenue increase to USD 248 million, and ProBio exhibiting a robust 511% growth to USD 247 million. Bestzyme also experienced a revenue rise of 8.4% to USD 28.3 million. Legend Biotech's CAR-T product, CARVYKTI, treated over 7,500 patients and saw a 136% increase in net trade sales to USD 439 million. GenScript forecasts continued growth, with GenScript Life Science's full-year revenue expected to increase by 13% to 15% and anticipates ProBio to recognize additional milestone payments in the second half. The company maintains a strong cash position of USD 970 million, supporting global expansion and R&D initiatives. Additionally, GenScript remains committed to advancing ESG initiatives, earning a silver medal from EcoVadis and an AA rating from MSCI ESG, reflecting their dedication to sustainability and governance.

Genscript Biotech Financial Statement Overview

Summary
Genscript Biotech shows strong revenue growth and a solid balance sheet, but struggles with profitability and consistent cash flow. The company needs to improve operational efficiency and manage capital expenditures for sustainable success.
Income Statement
65
Positive
Genscript Biotech has shown significant revenue growth over the years, with a compound annual growth rate in revenue from 2019 to 2024. The gross profit margin remains strong, indicating efficient cost management. However, the company has struggled with profitability, as reflected in negative EBIT and net profit margins in several years, despite a positive net income in 2024 due to exceptional items. The trajectory indicates improving top-line growth but persistent challenges in achieving sustainable profitability.
Balance Sheet
75
Positive
The balance sheet reflects a strong equity position with the equity ratio consistently above 50%, indicating financial stability and low leverage. The debt-to-equity ratio is manageable, supporting a stable financial structure. Improvements in asset base and shareholder equity over the years suggest healthy growth, although fluctuations in cash reserves may indicate liquidity management challenges.
Cash Flow
60
Neutral
Cash flow from operations has improved in 2024, turning positive after several years of negative figures, demonstrating progress in cash generation. Nonetheless, the free cash flow remains negative, impacted by significant capital expenditures and investments, which could pose liquidity risks. The operating cash flow to net income ratio improved, but long-term sustainability of positive cash flow remains uncertain without consistent profitability.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue551.89M594.49M839.53M625.70M490.10M390.85M
Gross Profit285.77M272.13M270.63M304.08M282.52M255.89M
EBITDA397.29M70.43M-249.42M-389.04M-477.27M-174.71M
Net Income3.11B2.96B-95.48M-226.85M-358.71M-204.94M
Balance Sheet
Total Assets5.43B5.28B3.39B2.55B2.23B1.45B
Cash, Cash Equivalents and Short-Term Investments938.36M621.18M1.93B1.46B1.41B772.38M
Total Debt548.52M723.74M416.99M349.80M156.45M55.00M
Total Liabilities1.01B954.91M1.34B1.18B846.17M631.82M
Stockholders Equity4.42B4.32B1.39B1.01B1.05B901.71M
Cash Flow
Free Cash Flow200.49M-72.27M-444.62M-336.40M-269.83M-272.97M
Operating Cash Flow232.62M75.65M-286.91M-120.29M-136.79M-151.09M
Investing Cash Flow-98.64M-1.46B-357.73M-443.30M-212.55M-100.17M
Financing Cash Flow26.40M66.52M1.07B419.32M902.14M624.20M

Genscript Biotech Technical Analysis

Technical Analysis Sentiment
Negative
Last Price13.50
Price Trends
50DMA
15.87
Negative
100DMA
16.61
Negative
200DMA
14.81
Negative
Market Momentum
MACD
-0.68
Positive
RSI
34.21
Neutral
STOCH
24.52
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:1548, the sentiment is Negative. The current price of 13.5 is below the 20-day moving average (MA) of 14.98, below the 50-day MA of 15.87, and below the 200-day MA of 14.81, indicating a bearish trend. The MACD of -0.68 indicates Positive momentum. The RSI at 34.21 is Neutral, neither overbought nor oversold. The STOCH value of 24.52 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:1548.

Genscript Biotech Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
69
Neutral
HK$36.55B24.616.00%1.56%12.35%34.32%
66
Neutral
HK$35.22B39.5727.37%2.57%18.79%
60
Neutral
$29.36B-20.65
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
43
Neutral
HK$37.15B-23.40-15.06%39.02%48.26%
42
Neutral
HK$15.98B-9.41-30.41%23.87%30.08%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:1548
Genscript Biotech
13.50
3.86
40.04%
HK:9688
Zai Lab Ltd
14.30
-6.30
-30.58%
HK:1877
Shanghai Junshi Biosciences Co., Ltd. Class H
24.00
11.32
89.27%
HK:2096
Simcere Pharmaceutical Group Limited
13.09
6.28
92.22%
HK:2696
Shanghai Henlius Biotech, Inc. Class H
64.80
42.55
191.24%
HK:6821
Asymchem Laboratories (Tianjin) Co., Ltd. Class H
77.25
25.79
50.12%

Genscript Biotech Corporate Events

Legend Biotech Unveils Promising Data at 2025 ASH Meeting
Dec 7, 2025

Legend Biotech Corporation, an associate of Genscript Biotech, announced new long-term clinical and translational data for its CARVYKTI® therapy from the CARTITUDE studies at the 2025 ASH Annual Meeting. This announcement highlights Legend’s ongoing advancements in treating relapsed/refractory multiple myeloma and introduces first-in-human data for a new dual-targeted CAR-T candidate, potentially strengthening its position in the cell therapy market.

Genscript Biotech Announces Q3 2025 Results for Legend Biotech
Nov 12, 2025

Genscript Biotech Corporation announced the financial results for the third quarter of 2025 for its associate, Legend Biotech Corporation, which is listed on the Nasdaq Global Select Market. The announcement highlights that these results pertain solely to Legend Biotech, and investors are advised to exercise caution when dealing with Genscript’s securities, indicating a focus on transparency and risk management.

Genscript Biotech’s Associate to Present New Data at Hematology Meeting
Nov 3, 2025

Genscript Biotech Corporation announced that its associate, Legend Biotech Corporation, will present new data on CARVYKTI® and other pipeline products at the upcoming American Society of Hematology Annual Meeting. This announcement highlights Legend’s ongoing efforts in the field of hematology and could potentially enhance its industry positioning by showcasing advancements in their product offerings.

Genscript Biotech Reports Strong CARVYKTI® Sales in Q3 2025
Oct 14, 2025

Genscript Biotech Corporation announced that its associate, Legend Biotech, reported approximately $524 million in net trade sales for CARVYKTI® in the quarter ending September 2025. This figure highlights the product’s strong market performance under the collaboration with Janssen Biotech, Inc., indicating a positive impact on the company’s operations and industry positioning.

Genscript Biotech’s ProBio Receives Significant Sublicense Revenue Boost
Oct 14, 2025

Genscript Biotech Corporation announced that its subsidiary, ProBio, received approximately RMB479.7 million (US$67.5 million) as the second installment of sublicense revenue under an agreement with LaNova Medicines Ltd. This payment is related to the sublicense of anti-PD-1 single domain antibodies, which are part of LaNova’s investigational PD-1/VEGF bispecific antibody, LM-299. The cumulative payments received under this agreement now total approximately RMB2.0 billion (US$283.6 million). These funds will enhance ProBio’s cash reserves and support further molecular discovery and development, reinforcing its position in the biotechnology market.

Genscript Biotech Grants Share Awards to Boost Employee Engagement
Sep 21, 2025

Genscript Biotech Corporation announced the grant of 774,960 Share Awards under its 2019 RSU Scheme to an executive director and employee grantees. This move is part of the company’s strategy to align employee incentives with performance, featuring a vesting period of approximately three years and a clawback mechanism to ensure compliance with performance targets. The initiative reflects Genscript’s commitment to fostering employee engagement and maintaining robust corporate governance.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 10, 2025