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Harvard Bioscience (HBIO)
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Harvard Bioscience (HBIO) AI Stock Analysis

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HBIO

Harvard Bioscience

(NASDAQ:HBIO)

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Neutral 50 (OpenAI - 4o)
Rating:50Neutral
Price Target:
$0.50
▲(25.00% Upside)
Harvard Bioscience's stock score reflects significant financial challenges and a weak valuation, partially offset by moderate technical indicators and positive operational improvements highlighted in the earnings call. The company's ability to manage cash flow and reduce debt provides some optimism, but ongoing profitability issues and external risks remain concerns.
Positive Factors
Strong Cash Flow Growth
The substantial increase in cash flow from operations indicates improved cash generation, enhancing financial flexibility and supporting long-term investments and debt reduction.
Successful New Product Launches
The introduction of innovative products like the SoHo Telemetry platform positions the company to capture new market opportunities and drive future revenue growth.
Debt Reduction
Reducing net debt enhances the company's balance sheet strength, lowers interest expenses, and increases financial stability, supporting long-term strategic initiatives.
Negative Factors
Decline in Revenue
The year-over-year revenue decline reflects challenges in maintaining market share and could hinder the company's ability to invest in growth and innovation.
Revenue Decline in Key Markets
Significant revenue declines in key markets like the Americas and APAC could impact overall financial performance and limit growth potential in these regions.
Challenges with NIH Funding
Delays in NIH funding can lead to prolonged sales cycles and reduced demand from academic institutions, affecting revenue stability and growth prospects.

Harvard Bioscience (HBIO) vs. SPDR S&P 500 ETF (SPY)

Harvard Bioscience Business Overview & Revenue Model

Company DescriptionHarvard Bioscience (HBIO) is a global provider of innovative tools, instruments, and consumables for life science research. The company operates primarily in the biotechnology and pharmaceutical sectors, offering a wide range of products that facilitate research in areas such as drug discovery, neuroscience, and regenerative medicine. Core products include laboratory instruments, precision measurement devices, and advanced technologies for cellular and molecular biology applications.
How the Company Makes MoneyHarvard Bioscience generates revenue through the sale of its scientific instruments, equipment, and consumables used in life science research. The company has multiple key revenue streams, including direct sales of laboratory instruments, recurring revenue from consumables, and revenue from software and service contracts. Additionally, HBIO benefits from partnerships with academic institutions, research organizations, and pharmaceutical companies, which can lead to increased sales opportunities and collaborations that enhance its market presence. The company's strategic focus on innovation and new product development also contributes significantly to its earnings, as it aims to meet the evolving needs of researchers in various scientific fields.

Harvard Bioscience Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 05, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong operational improvements, a significant increase in backlog and order growth, successful product launches, and positive cash flow management. However, these positives were somewhat offset by year-over-year revenue decline, challenges in the China market, and uncertainty due to the U.S. government shutdown affecting NIH funding. Overall, the company's efforts to enhance operational efficiency and increase product demand reflect a positive outlook despite some ongoing challenges.
Q3-2025 Updates
Positive Updates
Revenue and Margin Performance
Revenue for Q3 2025 was $20.6 million, at the high end of the guidance range of $19-21 million, with a slight sequential increase in a typically weak quarter. Gross margin improved to 58.4%, exceeding the guidance range of 56-58%.
Operational Improvements
Adjusted EBITDA increased to $2 million from $1.3 million in Q3 2024. Operating expenses declined by $1.4 million due to efficiency measures, leading to improved adjusted operating income.
Product and Market Advancements
Successful launch of the Incub8 Multiwell System and expanded distribution agreement with Fisher Scientific. Increased demand for the SoHo Telemetry and Biochrom amino acid analyzer.
Strong Backlog and Order Growth
The backlog reached its highest level in nearly two years, with quarterly order growth for the first time in over 12 months and a strong uptick in Europe.
Positive Cash Flow and Debt Reduction
Generated $6.8 million in operating cash flow year-to-date, with net debt reduced by over $6 million from year-end 2024 to $27.5 million.
Negative Updates
Revenue Decline Year-Over-Year
Revenue decreased from $22 million in Q3 2024 to $20.6 million in Q3 2025, reflecting a year-over-year decline.
Challenges in China
Revenue in China was down 6.3% sequentially and 19.6% year-over-year, despite recent positive developments in trade talks.
Potential Impact of U.S. Government Shutdown
Guidance reflects potential risks from a prolonged U.S. government shutdown, which could delay NIH funding and impact academic customer orders.
Company Guidance
During the third quarter of 2025, Harvard Bioscience reported revenue of $20.6 million, reaching the high end of their guidance range of $19 million to $21 million. The company achieved a gross margin of 58.4%, surpassing their guidance of 56% to 58%, and marked an improvement from 58.1% in the same quarter of the prior year. They recorded an adjusted EBITDA of $2 million, an increase from $1.3 million in the third quarter of 2024. Operating expenses were reduced by $1.4 million year-over-year, contributing to an improved adjusted operating income of $1.5 million compared to $0.8 million in the previous year. The company also maintained positive operating cash flow, generating $1.1 million in the third quarter, contributing to a year-to-date cash flow from operations of $6.8 million, a significant improvement from a negative $0.3 million in the prior year. Harvard Bioscience ended the quarter with a net debt of $27.5 million, reflecting a reduction of over $6 million from year-end 2024. The company anticipates fourth-quarter revenue to range between $22.5 million and $24.5 million, factoring in potential impacts from a prolonged U.S. government shutdown, with expected gross margins between 58% and 60%.

Harvard Bioscience Financial Statement Overview

Summary
Harvard Bioscience faces significant financial challenges with declining revenues, negative profitability, and high leverage. Despite some positive signs in cash flow generation, the overall financial health remains weak, requiring strategic improvements.
Income Statement
35
Negative
Harvard Bioscience's income statement reveals significant challenges. The company has experienced declining revenues, with a negative revenue growth rate in the TTM period. Profitability metrics are concerning, with negative net profit and EBIT margins indicating operational inefficiencies. The gross profit margin has decreased slightly over time, suggesting pressure on cost management. Overall, the income statement reflects a struggling financial performance with limited profitability.
Balance Sheet
40
Negative
The balance sheet shows a high debt-to-equity ratio in the TTM period, indicating increased leverage and potential financial risk. Return on equity is negative, reflecting ongoing losses and inefficiencies in generating shareholder value. The equity ratio has decreased, suggesting a weakening financial position. While the company has managed to reduce debt over time, the current leverage level remains a concern.
Cash Flow
50
Neutral
Cash flow analysis presents a mixed picture. The company has achieved positive free cash flow growth in the TTM period, a positive sign of cash generation. However, the operating cash flow to net income ratio is low, indicating challenges in converting earnings into cash. The free cash flow to net income ratio is positive, suggesting some ability to generate cash despite net losses. Overall, cash flow management shows some improvement but remains constrained by operational challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue87.37M94.14M112.25M113.33M118.90M102.10M
Gross Profit48.59M54.77M66.07M60.82M67.65M58.04M
EBITDA-44.78M-1.47M8.03M944.00K9.02M5.17M
Net Income-53.84M-12.40M-3.42M-9.52M-288.00K-7.81M
Balance Sheet
Total Assets77.99M126.64M137.37M145.36M162.34M156.25M
Cash, Cash Equivalents and Short-Term Investments6.82M4.11M4.28M4.51M7.82M8.32M
Total Debt7.33M44.49M42.77M54.24M56.96M57.60M
Total Liabilities63.92M63.30M64.29M73.14M78.94M79.57M
Stockholders Equity14.07M63.34M73.07M72.22M83.40M76.68M
Cash Flow
Free Cash Flow7.44M-1.20M11.72M-438.00K-83.00K8.18M
Operating Cash Flow8.55M1.44M14.03M1.15M1.26M9.33M
Investing Cash Flow-1.73M-1.34M-1.80M-1.59M-1.34M-1.40M
Financing Cash Flow-5.10M-131.00K-12.13M-2.84M-252.00K-7.97M

Harvard Bioscience Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.40
Price Trends
50DMA
0.46
Positive
100DMA
0.47
Positive
200DMA
0.59
Negative
Market Momentum
MACD
0.03
Negative
RSI
56.80
Neutral
STOCH
29.62
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HBIO, the sentiment is Positive. The current price of 0.4 is below the 20-day moving average (MA) of 0.47, below the 50-day MA of 0.46, and below the 200-day MA of 0.59, indicating a neutral trend. The MACD of 0.03 indicates Negative momentum. The RSI at 56.80 is Neutral, neither overbought nor oversold. The STOCH value of 29.62 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for HBIO.

Harvard Bioscience Risk Analysis

Harvard Bioscience disclosed 31 risk factors in its most recent earnings report. Harvard Bioscience reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Harvard Bioscience Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
$7.20M0.735.90%-4.99%-19.11%
52
Neutral
$17.40M-0.92-85.01%-16.59%43.20%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$24.21M-135.62%-10.60%-271.93%
48
Neutral
$25.18M-2.81-10.80%-0.24%50.45%
47
Neutral
$23.44M-5.47-66.08%133.00%29.69%
38
Underperform
$29.73M-4.35-123.50%7.84%-43.00%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HBIO
Harvard Bioscience
0.54
-1.91
-77.96%
RVP
Retractable Technologies
0.82
0.11
15.49%
EKSO
EKSO BIONICS
4.67
-6.94
-59.78%
MLSS
Milestone Scientific
0.40
-0.30
-42.86%
NXGL
NexGel Inc
2.48
-1.02
-29.14%
MHUA
Meihua International Medical Technologies Co., Ltd.
0.22
-0.27
-55.10%

Harvard Bioscience Corporate Events

Harvard Bioscience Reports Q3 2025 Financial Results
Nov 7, 2025

Harvard Bioscience, Inc. is a prominent developer and manufacturer in the life sciences sector, providing technologies and services for research, drug discovery, and preclinical testing, with a global presence in the United States, Europe, and China.

Delistings and Listing ChangesRegulatory Filings and Compliance
Harvard Bioscience Granted Nasdaq Compliance Extension
Neutral
Oct 3, 2025

On October 2, 2025, Harvard Bioscience received a notification from Nasdaq granting an additional 180 days, until March 30, 2026, to comply with the minimum bid price requirement of $1.00 per share for continued listing on the Nasdaq Capital Market. The company’s stock will be transferred from the Nasdaq Global Market to the Nasdaq Capital Market, effective October 3, 2025, as part of this compliance effort. Failure to meet the requirement by the deadline could result in delisting, but the company plans to monitor its stock price and consider options like a reverse stock split to regain compliance.

The most recent analyst rating on (HBIO) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Harvard Bioscience stock, see the HBIO Stock Forecast page.

Executive/Board Changes
Harvard Bioscience Appoints Stephen DeNelsky to Board
Positive
Sep 9, 2025

On September 5, 2025, Harvard Bioscience appointed Stephen DeNelsky to its Board of Directors, effective immediately, and he will also serve on the Nominating & Governance Committee. DeNelsky, a veteran in the life sciences industry with 30 years of experience, is expected to bring valuable expertise in financial strategy to the company, enhancing its governance and long-term value creation.

The most recent analyst rating on (HBIO) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Harvard Bioscience stock, see the HBIO Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesPrivate Placements and Financing
Harvard Bioscience Offers CFO $100K Retention Bonus
Positive
Aug 13, 2025

On August 12, 2025, Harvard Bioscience, Inc. announced a retention letter agreement with Mark Frost, its Interim Chief Financial Officer, offering him a $100,000 cash bonus upon successful refinancing of the company’s existing term loan and senior revolving credit facility by March 15, 2026. This agreement replaces a previous $50,000 bonus offer and includes provisions for salary and benefits continuation if Mr. Frost’s employment is terminated without cause before the refinancing date, highlighting the company’s strategic focus on financial stability and leadership retention.

The most recent analyst rating on (HBIO) stock is a Buy with a $4.50 price target. To see the full list of analyst forecasts on Harvard Bioscience stock, see the HBIO Stock Forecast page.

Harvard Bioscience at Risk of Nasdaq Delisting: Implications for Investors and Business Stability
Aug 13, 2025

Harvard Bioscience faces a significant business risk as it has received a notification from Nasdaq indicating non-compliance with the minimum bid price requirement, which could lead to delisting. This situation poses a threat to the company’s ability to raise capital, affects the liquidity and market price of its common stock, and could result in a loss of investor confidence. The company has until October 1, 2025, to regain compliance, potentially through a reverse stock split, but there is no guarantee of success. Delisting could also impact employee morale, customer trust, and business development opportunities.

Harvard Bioscience Reports Q2 2025 Financial Results
Aug 12, 2025

Harvard Bioscience, Inc. is a prominent developer and manufacturer in the life sciences sector, providing essential technologies for research, drug discovery, and preclinical testing, with a global presence across the United States, Europe, and China.

Harvard Bioscience Surpasses Revenue Guidance Amid Challenges
Aug 12, 2025

The recent earnings call for Harvard Bioscience painted a picture of cautious optimism, with the company demonstrating strong financial discipline. Despite challenges such as regional revenue declines in the Americas and APAC regions, the company exceeded its revenue guidance and made significant strides in product pipeline development. The sentiment was one of stabilizing the business while positioning for long-term growth.

Business Operations and StrategyPrivate Placements and Financing
Harvard Bioscience Amends Credit Agreement with Lenders
Negative
Aug 11, 2025

On August 8, 2025, Harvard Bioscience, Inc. entered into a Sixth Amendment to its Credit Agreement with Citizens Bank and other lenders. The amendment waives certain defaults and adjusts financial covenants, but raises concerns about the company’s ability to continue operations past December 2025 without securing additional capital or refinancing its debt.

The most recent analyst rating on (HBIO) stock is a Buy with a $4.50 price target. To see the full list of analyst forecasts on Harvard Bioscience stock, see the HBIO Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 07, 2025