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Harvard Bioscience (HBIO)
NASDAQ:HBIO
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Harvard Bioscience (HBIO) AI Stock Analysis

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HBIO

Harvard Bioscience

(NASDAQ:HBIO)

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Neutral 49 (OpenAI - 4o)
Rating:49Neutral
Price Target:
$0.50
▲(13.64% Upside)
Harvard Bioscience's overall stock score reflects significant financial and valuation challenges, with profitability and leverage being major concerns. Technical analysis indicates bearish momentum, further weighing on the score. However, the earnings call highlights some positive aspects, such as exceeding revenue guidance and strong cash flow, offering potential for recovery if operational efficiencies are improved.
Positive Factors
Strong Cash Flow and Debt Reduction
The significant increase in cash flow and reduction in net debt enhances financial flexibility, allowing Harvard Bioscience to invest in growth opportunities and manage obligations more effectively, supporting long-term stability.
Successful New Product Launches
New product launches, like the SoHo Telemetry platform, expand the company's product offerings and market reach, driving future revenue growth and strengthening its competitive position in the life sciences research market.
Revenue Guidance Exceeded
Exceeding revenue guidance indicates effective execution and demand for products, suggesting potential for continued growth and improved financial performance, enhancing investor confidence in the company's strategic direction.
Negative Factors
Decline in Revenue Compared to Previous Year
The year-over-year revenue decline highlights challenges in maintaining sales momentum, which could impact long-term growth prospects and necessitates strategic adjustments to regain market share.
Challenges with NIH Funding
Delays in NIH funding can lead to prolonged sales cycles and reduced revenue from academic institutions, affecting the company's ability to capitalize on opportunities in the preclinical research market.
Revenue Decline in Americas and China
Revenue declines in key markets like the Americas and China suggest competitive pressures and external challenges, potentially hindering the company's ability to achieve consistent growth across its geographic footprint.

Harvard Bioscience (HBIO) vs. SPDR S&P 500 ETF (SPY)

Harvard Bioscience Business Overview & Revenue Model

Company DescriptionHarvard Bioscience, Inc. develops, manufactures, and sells technologies, products, and services that enables fundamental research, discovery, and pre-clinical testing for drug development in the United States and internationally. The company offers cellular and molecular technology instruments, such as syringe and peristaltic pump products, as well as a range of instruments and accessories for tissue and organ-based lab research, including surgical products, infusion systems, and behavior research systems; and spectrophotometers, microplate readers, amino acid analyzers, gel electrophoresis equipment, and electroporation and electrofusion instruments. It also engages in the development and manufacture of precision scientific measuring instrumentation and equipment, which cover data acquisition systems with custom amplifier configurations for cellular analysis, micro electrode array solutions for in vivo recordings, and vitro-systems for extracellular recordings; and offers preclinical products. The company markets its products through sales organizations, websites, catalogs, and distributors to research scientists in pharmaceutical and biotechnology companies, universities, hospitals, and government laboratories, as well as to contract research organizations, academic labs, and government researchers. It primarily sells its products under Harvard Apparatus, DSI, Ponemah, Buxco, Biochrom, BTX, and MCS brand names. The company was founded in 1901 and is headquartered in Holliston, Massachusetts.
How the Company Makes MoneyHarvard Bioscience generates revenue through the sale of its scientific instruments, equipment, and consumables used in life science research. The company has multiple key revenue streams, including direct sales of laboratory instruments, recurring revenue from consumables, and revenue from software and service contracts. Additionally, HBIO benefits from partnerships with academic institutions, research organizations, and pharmaceutical companies, which can lead to increased sales opportunities and collaborations that enhance its market presence. The company's strategic focus on innovation and new product development also contributes significantly to its earnings, as it aims to meet the evolving needs of researchers in various scientific fields.

Harvard Bioscience Earnings Call Summary

Earnings Call Date:Aug 11, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 06, 2025
Earnings Call Sentiment Neutral
The earnings call revealed a mixed performance with some positive developments such as exceeding revenue guidance, strong cash flow, and new product launches, while facing challenges like year-over-year revenue decline and impacts from NIH funding delays and tariffs. However, the company has shown resilience by implementing cost efficiencies and addressing debt obligations.
Q2-2025 Updates
Positive Updates
Positive Financial Metrics
Revenue for Q2 2025 was $20.5 million, exceeding guidance of $18 million to $20 million, primarily due to higher Chinese shipments. Adjusted operating income improved to $1 million compared to $0.8 million in Q2 2024. Adjusted EBITDA increased to $1.5 million from $1.3 million in the previous year.
Strong Cash Flow and Debt Reduction
Year-to-date cash flow from operations was $5.7 million, significantly higher than $0.6 million in the same period last year. Net debt decreased over $4 million from year-end to $27.9 million from $32 million.
Successful New Product Launches
New product pipeline includes the launch of the SoHo Telemetry platform with cardiac and neuromonitoring capabilities, and the VivaMARS automation pilot with Labcorp. Achieved $1 million in consumable revenue from BTX bioproduction.
Stability in Tariff Situation
Tariffs with China have stabilized at a 10% level, allowing orders and shipments to return to normal behavior after initial halts.
Negative Updates
Decline in Revenue Compared to Previous Year
Q2 2025 revenue of $20.5 million was below the $23.1 million from the prior year. Gross margin decreased to 56.4% from 57.2% in Q2 2024.
Revenue Decline in Americas and China
Americas revenue declined sequentially by 5.4% and 11.7% year-over-year, primarily due to budget clarity issues with academics and NIH. APAC revenue was down over 25% sequentially and year-over-year due to tariffs.
Challenges with NIH Funding
NIH funding delays have extended academic purchasing cycles, impacting preclinical sales in the Americas.
Company Guidance
During the second quarter of 2025, Harvard Bioscience reported revenue of $20.5 million, surpassing their guidance range of $18 million to $20 million, primarily due to higher shipments in China. The gross margin stood at 56.4%, within their guidance of 55% to 57%, although it showed a slight decline from 57.2% in the previous year. Operating expenses decreased by $2 million, leading to an improvement in adjusted operating income to $1 million from $0.8 million in Q2 2024. Adjusted EBITDA increased to $1.5 million compared to $1.3 million in the same quarter of the previous year, driven by reduced operating expenses. Cash flow from operations was strong at $5.7 million year-to-date, with a $2.8 million contribution in Q2. The company also reduced net debt to $27.9 million from $32 million at year-end, reflecting a quarterly principal payment of $1 million. Looking ahead, they provided guidance for Q3 2025 with expected revenue between $19 million and $21 million and a gross margin range of 56% to 58%.

Harvard Bioscience Financial Statement Overview

Summary
Harvard Bioscience faces significant financial challenges, particularly in profitability and leverage. The income statement reflects substantial losses and declining revenues, while the balance sheet shows high debt levels and negative returns on equity. However, the cash flow statement provides a glimmer of hope with strong free cash flow growth, suggesting potential for recovery if operational efficiencies can be improved.
Income Statement
45
Neutral
Harvard Bioscience's income statement shows significant challenges with profitability. The TTM data reveals a negative net profit margin of -64.68% and a declining revenue growth rate of -2.90%. The EBIT and EBITDA margins are also negative, indicating operational inefficiencies. Despite a reasonable gross profit margin of 56.89%, the company struggles with high operational costs leading to substantial net losses.
Balance Sheet
50
Neutral
The balance sheet reflects a mixed financial position. The debt-to-equity ratio has improved in the TTM period, indicating reduced leverage, but remains a concern with a high total debt level. The return on equity is significantly negative at -160.02%, highlighting poor returns for shareholders. The equity ratio is not provided, but the overall asset base has decreased, suggesting potential liquidity issues.
Cash Flow
60
Neutral
Cash flow analysis shows some positive trends. The TTM free cash flow growth rate is exceptionally high at 739.59%, indicating improved cash generation. The operating cash flow to net income ratio is 0.12, suggesting some ability to cover net losses with operating cash. However, the free cash flow to net income ratio of 0.76 indicates that while cash flow is improving, it is not yet sufficient to cover net losses fully.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue88.75M94.14M112.25M113.33M118.90M102.10M
Gross Profit49.33M54.77M66.07M60.82M67.65M58.04M
EBITDA-46.80M-1.47M8.03M944.00K11.31M5.49M
Net Income-57.41M-12.40M-3.42M-9.52M-288.00K-7.81M
Balance Sheet
Total Assets80.09M126.64M137.37M145.36M162.34M156.25M
Cash, Cash Equivalents and Short-Term Investments7.44M4.11M4.28M4.51M7.82M8.32M
Total Debt43.31M44.49M42.77M54.24M56.96M57.60M
Total Liabilities64.36M63.30M64.29M73.14M78.94M79.57M
Stockholders Equity15.73M63.34M73.07M72.22M83.40M76.68M
Cash Flow
Free Cash Flow4.92M-1.20M11.72M-438.00K-83.00K8.18M
Operating Cash Flow6.62M1.44M14.03M1.15M1.26M9.33M
Investing Cash Flow-2.49M-1.34M-1.80M-1.59M-1.34M-1.40M
Financing Cash Flow-1.72M-131.00K-12.13M-2.84M-252.00K-7.97M

Harvard Bioscience Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.44
Price Trends
50DMA
0.48
Negative
100DMA
0.46
Negative
200DMA
0.82
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
42.03
Neutral
STOCH
12.70
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HBIO, the sentiment is Negative. The current price of 0.44 is below the 20-day moving average (MA) of 0.46, below the 50-day MA of 0.48, and below the 200-day MA of 0.82, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 42.03 is Neutral, neither overbought nor oversold. The STOCH value of 12.70 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HBIO.

Harvard Bioscience Risk Analysis

Harvard Bioscience disclosed 31 risk factors in its most recent earnings report. Harvard Bioscience reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Harvard Bioscience Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
$211.20M43.599.30%8.13%1293.06%
49
Neutral
$19.58M-138.36%-12.24%-427.45%
46
Neutral
$35.83M-5.25-208.80%7.84%-43.00%
44
Neutral
$15.47M-0.42-816.54%98.61%-1.98%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HBIO
Harvard Bioscience
0.44
-2.10
-82.68%
INFU
InfuSystem Holdings
10.36
3.87
59.63%
MLSS
Milestone Scientific
0.46
-0.42
-47.73%
MBOT
Microbot Medical
3.05
2.17
246.59%
FEMY
Femasys
0.35
-0.77
-68.75%

Harvard Bioscience Corporate Events

Executive/Board Changes
Harvard Bioscience Appoints Stephen DeNelsky to Board
Positive
Sep 9, 2025

On September 5, 2025, Harvard Bioscience appointed Stephen DeNelsky to its Board of Directors, effective immediately, and he will also serve on the Nominating & Governance Committee. DeNelsky, a veteran in the life sciences industry with 30 years of experience, is expected to bring valuable expertise in financial strategy to the company, enhancing its governance and long-term value creation.

The most recent analyst rating on (HBIO) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Harvard Bioscience stock, see the HBIO Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesPrivate Placements and Financing
Harvard Bioscience Offers CFO $100K Retention Bonus
Positive
Aug 13, 2025

On August 12, 2025, Harvard Bioscience, Inc. announced a retention letter agreement with Mark Frost, its Interim Chief Financial Officer, offering him a $100,000 cash bonus upon successful refinancing of the company’s existing term loan and senior revolving credit facility by March 15, 2026. This agreement replaces a previous $50,000 bonus offer and includes provisions for salary and benefits continuation if Mr. Frost’s employment is terminated without cause before the refinancing date, highlighting the company’s strategic focus on financial stability and leadership retention.

The most recent analyst rating on (HBIO) stock is a Buy with a $4.50 price target. To see the full list of analyst forecasts on Harvard Bioscience stock, see the HBIO Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Harvard Bioscience Amends Credit Agreement with Lenders
Negative
Aug 11, 2025

On August 8, 2025, Harvard Bioscience, Inc. entered into a Sixth Amendment to its Credit Agreement with Citizens Bank and other lenders. The amendment waives certain defaults and adjusts financial covenants, but raises concerns about the company’s ability to continue operations past December 2025 without securing additional capital or refinancing its debt.

The most recent analyst rating on (HBIO) stock is a Buy with a $4.50 price target. To see the full list of analyst forecasts on Harvard Bioscience stock, see the HBIO Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 24, 2025