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Harvard Bioscience (HBIO)
NASDAQ:HBIO

Harvard Bioscience (HBIO) AI Stock Analysis

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HBIO

Harvard Bioscience

(NASDAQ:HBIO)

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Neutral 50 (OpenAI - 5.2)
Rating:50Neutral
Price Target:
$4.50
â–²(1025.00% Upside)
Action:ReiteratedDate:03/20/26
HBIO’s score is held back primarily by weak financial performance (sharp TTM revenue decline and large losses), with only partial offset from positive near-term cash generation. The latest earnings call provides a constructive but modest recovery outlook (limited growth and EBITDA improvement guidance), while technical indicators remain soft and valuation is difficult to support due to ongoing losses and no dividend yield.
Positive Factors
Cash generation
Despite large reported GAAP losses, the business still produced positive operating and free cash flow on a TTM basis. Consistent positive cash flow underpins short-to-mid-term liquidity, funds operations and prioritizes deleveraging or targeted reinvestment in higher-margin NPIs over the next 2–6 months.
Negative Factors
Weak profitability & revenue decline
Material margin deterioration and continuing revenue contraction indicate the core business has struggled to scale costs with lower volume. Sustained negative margins and declining top line increase execution risk and constrain reinvestment capacity over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Cash generation
Despite large reported GAAP losses, the business still produced positive operating and free cash flow on a TTM basis. Consistent positive cash flow underpins short-to-mid-term liquidity, funds operations and prioritizes deleveraging or targeted reinvestment in higher-margin NPIs over the next 2–6 months.
Read all positive factors

Harvard Bioscience (HBIO) vs. SPDR S&P 500 ETF (SPY)

Harvard Bioscience Business Overview & Revenue Model

Company Description
Harvard Bioscience, Inc. develops, manufactures, and sells technologies, products, and services that enables fundamental research, discovery, and pre-clinical testing for drug development in the United States and internationally. The company offer...
How the Company Makes Money
HBIO primarily makes money by selling life science research tools and instrumentation to laboratories and research organizations. Key revenue streams include: (1) instrument and equipment sales—revenue from the sale of lab devices and systems used...

Harvard Bioscience Earnings Call Summary

Earnings Call Date:Mar 17, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:Apr 30, 2026
Earnings Call Sentiment Neutral
The call conveyed a cautiously optimistic tone: management highlighted meaningful operational and financial improvements (margin expansion, adjusted EBITDA growth, refinancing, manufacturing consolidation, stronger cash flow, remediation of controls, and clear strategic priorities toward translational science and higher-margin NPIs). However, notable headwinds remain — full-year revenue declined 8% YoY, a large goodwill impairment drove a substantial GAAP loss, regional softness (Europe, Americas), dependence on NIH timing and tariff risk, and near-term EBITDA pressure from reinstated compensation. Guidance for modest revenue growth (2%–4%) and mid-single to high-single-digit adjusted EBITDA growth (6%–10%) indicates management expects recovery to continue but not a dramatic turnaround in 2026.
Positive Updates
Fourth Quarter Revenue Above Midpoint of Guidance
Q4 revenue of $23.7M was just above the midpoint of guidance ($22.5M–$24.5M) and represented sequential revenue growth of 15%.
Negative Updates
Full-Year Revenue Decline
Full-year 2025 revenue was $86.6M, down 8% from $94.1M in 2024, primarily due to tariffs and delayed NIH funding impacting order timing (notably preclinical telemetry).
Read all updates
Q4-2025 Updates
Negative
Fourth Quarter Revenue Above Midpoint of Guidance
Q4 revenue of $23.7M was just above the midpoint of guidance ($22.5M–$24.5M) and represented sequential revenue growth of 15%.
Read all positive updates
Company Guidance
Management's guidance for 2026 calls for Q1 revenue of $20.0–$22.0 million, adjusted gross margin of 57%–59% and adjusted EBITDA of $1.0–$2.2 million; for the full year they expect revenue growth of 2%–4% (implying roughly $88.3–$90.1 million on 2025's $86.6M), adjusted gross margin of 58%–60%, and adjusted EBITDA growth of 6%–10% (roughly $8.6–$8.9 million on 2025's $8.1M), with revenue expected to ramp through the year driven by stronger NPI (BTX and Mesh MEA are each expected to grow in double digits), adjusted EBITDA guidance tied to a debt covenant, and management noting that reinstated bonuses and merit increases will depress year‑over‑year adjusted EBITDA comparisons.

Harvard Bioscience Financial Statement Overview

Summary
Financial profile is weak: TTM revenue declined to about $86.6M and profitability deteriorated sharply (operating margin ~-57%, net margin ~-62%). Positives include positive TTM operating cash flow (~$6.5M) and free cash flow (~$5.1M), but cash generation has been volatile historically and the most recent balance-sheet inputs show inconsistencies, reducing confidence in the latest leverage snapshot.
Income Statement
18
Very Negative
Balance Sheet
42
Neutral
Cash Flow
55
Neutral
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue86.55M94.14M112.25M113.33M118.90M
Gross Profit45.88M54.77M66.07M60.82M67.65M
EBITDA5.32M-1.47M8.03M944.00K9.02M
Net Income-56.70M-12.40M-3.42M-9.52M-288.00K
Balance Sheet
Total Assets80.07M126.64M137.37M145.36M162.34M
Cash, Cash Equivalents and Short-Term Investments8.61M4.11M4.28M4.51M7.82M
Total Debt44.28M44.49M42.77M54.24M56.96M
Total Liabilities66.34M63.30M64.29M73.14M78.94M
Stockholders Equity13.73M63.34M73.07M72.22M83.40M
Cash Flow
Free Cash Flow5.62M-1.82M11.72M-438.00K-83.00K
Operating Cash Flow6.73M1.44M14.03M1.15M1.26M
Investing Cash Flow-1.86M-1.34M-1.80M-1.59M-1.34M
Financing Cash Flow-1.29M-131.00K-12.13M-2.84M-252.00K

Harvard Bioscience Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.40
Price Trends
50DMA
5.38
Positive
100DMA
6.07
Negative
200DMA
5.40
Negative
Market Momentum
MACD
-0.07
Negative
RSI
52.71
Neutral
STOCH
72.90
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HBIO, the sentiment is Positive. The current price of 0.4 is below the 20-day moving average (MA) of 5.10, below the 50-day MA of 5.38, and below the 200-day MA of 5.40, indicating a neutral trend. The MACD of -0.07 indicates Negative momentum. The RSI at 52.71 is Neutral, neither overbought nor oversold. The STOCH value of 72.90 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for HBIO.

Harvard Bioscience Risk Analysis

Harvard Bioscience disclosed 27 risk factors in its most recent earnings report. Harvard Bioscience reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Harvard Bioscience Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$32.28M-1.12-85.01%―-16.59%43.20%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$24.15M-0.52-388.56%―-10.60%-271.93%
46
Neutral
$22.69M-3.92-164.78%―0.59%-39.76%
45
Neutral
$6.76M-4.22-55.33%―73.38%34.87%
43
Neutral
$20.69M-1.84-8.13%―-0.95%58.17%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HBIO
Harvard Bioscience
5.40
0.81
17.65%
RVP
Retractable Technologies
0.69
>-0.01
-1.29%
EKSO
EKSO BIONICS
9.06
3.10
52.01%
MLSS
Milestone Scientific
0.28
-0.67
-70.38%
NXGL
NexGel Inc
0.61
-2.05
-77.03%

Harvard Bioscience Corporate Events

Business Operations and StrategyExecutive/Board ChangesPrivate Placements and Financing
Harvard Bioscience Highlights CFO Appointment and Strategic Repositioning
Positive
Mar 17, 2026
In its latest investor presentation dated March 2026, Harvard Bioscience outlines recent strategic and financial actions, including the appointment of John Duke as CEO effective July 2025 and Mark Frost as permanent CFO in March 2026, as well as a...
Business Operations and StrategyExecutive/Board ChangesStock Split
Harvard Bioscience Updates Executive Contracts and Finance Leadership
Positive
Mar 10, 2026
On March 6, 2026, Harvard Bioscience, Inc. amended and restated the employment agreement for Chief Executive Officer John Duke, extending his term to July 16, 2027 with automatic two‑year renewals, raising his annual base salary to $515,000 ...
Delistings and Listing ChangesRegulatory Filings and ComplianceShareholder MeetingsStock Split
Harvard Bioscience Approves Reverse Stock Split to Regain Compliance
Neutral
Mar 6, 2026
Harvard Bioscience held a special shareholder meeting on March 6, 2026, at which investors approved a reverse stock split and a potential meeting adjournment to secure that vote. Following the approval, the board set a 1-for-10 split ratio and fil...
Business Operations and Strategy
Harvard Bioscience Announces Major Global Manufacturing Consolidation
Positive
Jan 29, 2026
On January 23, 2026, Harvard Bioscience’s board approved “Project Viking,” a strategic consolidation of manufacturing aimed at improving efficiency and supporting long-term growth, centered on closing the Holliston, Massachusetts...
Business Operations and StrategyShareholder Meetings
Harvard Bioscience Lowers Quorum Requirement for Shareholders
Neutral
Jan 20, 2026
On January 19, 2026, Harvard Bioscience’s Board of Directors approved an amendment to the company’s Amended and Restated By-laws that lowers the quorum requirement for stockholder meetings from a majority to one-third of the shares ent...
Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
Harvard Bioscience Issues Strategic Investor Update Presentation
Positive
Jan 12, 2026
In January 2026, Harvard Bioscience released an investor update presentation outlining its business strategy, operational progress and financial outlook, emphasizing its leading positions in high-demand preclinical telemetry tools, organoid resear...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 20, 2026