Proteome Sciences PLC (GB:PRM)
LSE:PRM
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Proteome Sciences
(LSE:PRM)
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Rating:42Neutral
Price Target:
1.50 p
▼(-47.37% Downside)
Action:Reiterated
Date:05/12/26
The score is primarily constrained by weak financial performance, driven by declining revenue, negative gross profit, sustained losses, and a stressed balance sheet with rising debt and deeply negative equity. Technicals are only mildly supportive (short-term rebound but still below the 200-day average with negative MACD), while valuation is hindered by ongoing losses (negative P/E) and no dividend data.
Positive Factors
Specialized proteomics services
Proteome Sciences operates in a high-specialization niche offering proteomics and mass-spectrometry services. This technical expertise creates a durable competitive position versus general labs, supporting longer-term contract demand from drug developers and research institutions.
Negative Factors
Declining revenue and negative gross profit
Sustained revenue decline and negative gross margins show the business lacks sufficient scale or pricing power to cover direct costs. Persistent operating losses suggest structural issues in cost absorption and limit the firm's ability to reinvest in growth or R&D without external funding.
Read all positive and negative factors
Positive Factors
Negative Factors
Specialized proteomics services
Proteome Sciences operates in a high-specialization niche offering proteomics and mass-spectrometry services. This technical expertise creates a durable competitive position versus general labs, supporting longer-term contract demand from drug developers and research institutions.
Read all positive factors
Proteome Sciences (PRM) vs. iShares MSCI United Kingdom ETF (EWC)
Market Cap
£5.26M
Dividend YieldN/A
Average Volume (3M)476.64K
Price to Earnings (P/E)―
Beta (1Y)0.51
Revenue Growth-23.14%
EPS Growth9.57%
CountryUK
Employees36
SectorHealthcare
Sector Strength45
IndustryMedical - Diagnostics & Research
Share Statistics
EPS (TTM)-0.01
Shares Outstanding350,724,900
10 Day Avg. Volume209,671
30 Day Avg. Volume476,642
Financial Highlights & Ratios
PEG Ratio0.25
Price to Book (P/B)-0.77
Price to Sales (P/S)1.96
P/FCF Ratio-51.61
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)N/A
Revenue Forecast (FY)N/A
Proteome Sciences Business Overview & Revenue Model
Company Description
Proteome Sciences plc provides contract research services for the identification, validation, and application of protein biomarkers in the United States, the United Kingdom, and European Union. The company offers SysQuant provides comprehensive an...
How the Company Makes Money
Proteome Sciences makes money primarily by selling proteomics and mass spectrometry–based contract research and analytical services. Revenue is generated when customers (typically pharma/biotech companies and research institutions) pay for project...
Proteome Sciences Financial Statement Overview
Summary
Income Statement
18
Very Negative
Balance Sheet
12
Very Negative
Cash Flow
26
Negative
| Breakdown | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|
Income Statement | |||||
| Total Revenue | 3.76M | 4.89M | 5.03M | 7.78M | 5.12M |
| Gross Profit | -1.01M | -167.00K | 1.16M | 4.77M | 2.96M |
| EBITDA | -1.74M | -1.44M | -986.00K | 1.89M | 725.00K |
| Net Income | -3.06M | -3.41M | -2.44M | 1.32M | 72.00K |
Balance Sheet | |||||
| Total Assets | 8.26M | 9.21M | 11.46M | 12.43M | 10.04M |
| Cash, Cash Equivalents and Short-Term Investments | 781.00K | 1.13M | 2.03M | 3.99M | 2.39M |
| Total Debt | 15.77M | 14.52M | 13.47M | 11.91M | 11.69M |
| Total Liabilities | 17.79M | 15.72M | 14.52M | 13.28M | 12.82M |
| Stockholders Equity | -9.53M | -6.52M | -3.07M | -843.00K | -2.77M |
Cash Flow | |||||
| Free Cash Flow | -143.00K | -1.05M | -718.00K | 2.14B | 8.80B |
| Operating Cash Flow | -46.00K | -826.00K | -481.00K | 3.88B | 10.52B |
| Investing Cash Flow | -97.00K | -224.00K | -424.00K | -21.67B | 4.27B |
| Financing Cash Flow | -204.00K | 151.00K | -1.06M | -209.00K | -400.00K |
Proteome Sciences Technical Analysis
Negative
2.85
Price Trends
1.58
Negative
1.96
Negative
2.17
Negative
Market Momentum
0.01
Positive
46.83
Neutral
7.58
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:PRM, the sentiment is Negative. The current price of 2.85 is above the 20-day moving average (MA) of 1.57, above the 50-day MA of 1.58, and above the 200-day MA of 2.17, indicating a bearish trend. The MACD of 0.01 indicates Positive momentum. The RSI at 46.83 is Neutral, neither overbought nor oversold. The STOCH value of 7.58 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:PRM.
Proteome Sciences Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
58 Neutral | £6.43M | -0.39 | -122.54% | ― | -57.03% | -15.71% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
49 Neutral | £17.66M | -0.76 | -153.92% | ― | 65.60% | 74.84% | |
48 Neutral | £14.21M | -1.31 | -104.73% | ― | 29.64% | 28.51% | |
43 Neutral | £5.94M | -2.61 | -2.42% | ― | 102.28% | 95.58% | |
42 Neutral | £5.26M | -2.00 | 44.15% | ― | -23.14% | 9.57% | |
40 Underperform | £7.91M | -0.47 | -181.41% | ― | 12.12% | 54.24% |
* Healthcare Sector Average
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Proteome Sciences Corporate Events
Business Operations and StrategyFinancial DisclosuresShareholder Meetings
Proteome Sciences Wins Full Shareholder Backing at AGM
Positive
May 14, 2026
Proteome Sciences plc reported that all resolutions put to shareholders at its annual general meeting on 14 May 2026 were duly passed, including approval of the 2025 financial statements and the remuneration report. Investors also backed the reapp...
Business Operations and StrategyFinancial Disclosures
Proteome Sciences Sees Recovery in Reagent Sales and Strong Proteomics Outlook
Positive
May 14, 2026
Proteome Sciences reported progress in its services business, noting improved order levels and a continuing recovery in sales of its TMT and other reagents in the first half of the year. The company said recent investments over the past two years ...
Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresPrivate Placements and FinancingProduct-Related AnnouncementsShareholder Meetings
Proteome Sciences Bets on Services Growth and New Tags After TMT Slump
Neutral
Apr 15, 2026
Proteome Sciences reported a sharp decline in 2025 group revenue to £3.76m from £4.89m, as TMT reagent sales and royalties nearly halved due to deep U.S. National Institutes of Health funding cuts, though proteomic services revenue more ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.