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Proteome Sciences PLC (GB:PRM)
LSE:PRM
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Proteome Sciences (PRM) AI Stock Analysis

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GB:PRM

Proteome Sciences

(LSE:PRM)

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Underperform 40 (OpenAI - 4o)
Rating:40Underperform
Price Target:
1.50p
▼(-8.54% Downside)
Proteome Sciences' overall stock score is significantly impacted by its poor financial performance, characterized by declining revenues, negative profitability, and high debt levels. The technical analysis further indicates a bearish trend, with the stock trading below key moving averages and weak momentum indicators. The negative P/E ratio and lack of dividend yield highlight valuation concerns, contributing to the low overall score.
Positive Factors
Revenue Growth
The company's ability to achieve revenue growth indicates potential market demand and successful sales strategies, supporting long-term business sustainability.
EPS Growth
Earnings per share growth suggests improved profitability and operational efficiency, which can enhance shareholder value over time.
Industry Position
Focusing on proteomics positions the company in a niche market with high growth potential, leveraging advanced technologies for competitive advantage.
Negative Factors
Negative Profitability
Ongoing operational challenges with profitability can hinder the company's ability to reinvest in growth and maintain competitive positioning.
High Debt Levels
Excessive debt can strain financial resources, limiting strategic flexibility and increasing financial risk, which could impact long-term viability.
Negative Cash Flow
Negative cash flow indicates difficulties in generating sufficient cash to fund operations, potentially leading to liquidity issues and constraining growth.

Proteome Sciences (PRM) vs. iShares MSCI United Kingdom ETF (EWC)

Proteome Sciences Business Overview & Revenue Model

Company DescriptionProteome Sciences (PRM) is a biotechnology company specializing in proteomics and biomarker discovery. The company focuses on providing advanced analytical services and proprietary technologies aimed at understanding protein functions and their roles in diseases. Its core products include mass spectrometry-based proteomics services that aid in drug development, diagnostics, and personalized medicine across various sectors such as pharmaceuticals, biotechnology, and academic research.
How the Company Makes MoneyProteome Sciences generates revenue primarily through its contract research services, which involve offering proteomics analysis and biomarker discovery to pharmaceutical and biotechnology companies. These services are often provided on a fee-for-service basis, where clients pay for specific projects or studies tailored to their research needs. Additionally, the company may earn income from collaborations and partnerships with academic institutions and industry players, enabling shared research initiatives and technology licensing. Furthermore, Proteome Sciences could also monetize its proprietary technologies and software tools through licensing agreements, contributing to its overall revenue stream.

Proteome Sciences Financial Statement Overview

Summary
Proteome Sciences is facing substantial financial challenges across all financial statements. Declining revenues, negative profitability, and high debt levels indicate significant business risks. The negative equity and cash flow issues further exacerbate the company's financial instability.
Income Statement
20
Very Negative
The company has experienced declining revenue with a decrease from 5.03 million to 4.89 million over the last year, indicating a negative revenue growth rate. The negative EBIT and net income margins highlight ongoing operational challenges with profitability. These factors indicate financial instability in the income statement.
Balance Sheet
10
Very Negative
The company has a negative stockholders' equity, indicating that liabilities exceed assets, which is a significant concern. The debt-to-equity ratio cannot be calculated due to negative equity, but the high total debt level suggests potential solvency issues. This balance sheet position suggests high financial risk.
Cash Flow
15
Very Negative
Operating cash flow is negative, and free cash flow has worsened, indicating cash flow difficulties. The free cash flow to net income ratio is negative, reflecting challenges in generating cash relative to net income. These factors demonstrate weak cash flow management.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue4.53M4.89M5.03M23.74B22.59B16.95B
Gross Profit-32.00K670.00K1.65M4.77M2.96M2.58M
EBITDA-1.45M-1.51M-1.14M2.13M625.00K714.00K
Net Income-3.33M-3.41M-2.44M1.32M72.00K295.00K
Balance Sheet
Total Assets8.35M9.21M11.46M12.43M10.04M9.09M
Cash, Cash Equivalents and Short-Term Investments263.00K1.13M2.03M3.99M2.39M2.21M
Total Debt15.39M14.52M13.47M11.91M11.69M11.04M
Total Liabilities16.93M15.72M14.52M13.28M12.82M12.45M
Stockholders Equity-8.58M-6.52M-3.07M-843.00K-2.77M-3.36M
Cash Flow
Free Cash Flow-1.48M-1.05M-718.00K2.14B8.80B-9.07B
Operating Cash Flow-1.21M-826.00K-481.00K3.88B10.52B-7.74B
Investing Cash Flow-273.00K-224.00K-424.00K-21.67B4.27B-18.38B
Financing Cash Flow368.00K151.00K-1.06M-209.00K-400.00K-146.00K

Proteome Sciences Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.64
Price Trends
50DMA
1.88
Negative
100DMA
2.51
Negative
200DMA
3.02
Negative
Market Momentum
MACD
-0.09
Negative
RSI
40.83
Neutral
STOCH
47.34
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:PRM, the sentiment is Negative. The current price of 1.64 is below the 20-day moving average (MA) of 1.66, below the 50-day MA of 1.88, and below the 200-day MA of 3.02, indicating a bearish trend. The MACD of -0.09 indicates Negative momentum. The RSI at 40.83 is Neutral, neither overbought nor oversold. The STOCH value of 47.34 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:PRM.

Proteome Sciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
£16.95M-90.48%37.39%-126.19%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
£10.04M125.37%22.47%
48
Neutral
£10.43M-4.83-13.85%7.27%39.64%
40
Underperform
£5.92M-1.5612.19%18.12%
40
Underperform
£6.26M-0.11-333.59%45.22%55.71%
39
Underperform
£8.18M-1.23-181.41%12.12%54.24%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:PRM
Proteome Sciences
1.64
-1.03
-38.58%
GB:GDR
Genedrive
1.00
-0.83
-45.36%
GB:IXI
IXICO plc
11.00
-1.25
-10.20%
GB:OBD
Oxford BioDynamics
0.30
-1.06
-77.94%
GB:ABDX
Abingdon Health PLC
6.75
-0.60
-8.16%
GB:GENI
GENinCode UK Ltd.
2.15
-2.10
-49.41%

Proteome Sciences Corporate Events

Business Operations and StrategyFinancial Disclosures
Proteome Sciences Sees Growth in Services Amid Revenue Challenges
Neutral
Sep 25, 2025

Proteome Sciences reported a decline in total revenues for the first half of 2025, attributed to global trade upheavals and cuts in US research funding. Despite these challenges, the company’s proteomics services showed significant growth, particularly in Frankfurt and San Diego, with expectations of continued demand into 2026. The company is optimistic about future revenue growth, driven by increased orders and new product developments like DXT tags for multiplexing. However, sales of TMT reagents have been impacted by reduced R&D funding, though improvements are anticipated as the industry adapts.

The most recent analyst rating on (GB:PRM) stock is a Hold with a £3.00 price target. To see the full list of analyst forecasts on Proteome Sciences stock, see the GB:PRM Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 08, 2025