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Proteome Sciences PLC (GB:PRM)
LSE:PRM
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Proteome Sciences (PRM) AI Stock Analysis

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GB:PRM

Proteome Sciences

(LSE:PRM)

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Neutral 50 (OpenAI - 5.2)
Rating:50Neutral
Price Target:
2.00 p
▲(11.11% Upside)
Action:Reiterated
Date:07/09/26
The score is held back primarily by weak financial performance—declining revenue, negative gross profit, sustained losses, and a strained balance sheet with high debt and negative equity. Technicals are comparatively supportive (price above major moving averages with positive momentum), but valuation remains challenged due to negative earnings and no dividend data.
Positive Factors
Specialized proteomics services
The company’s core fee-for-service proteomics business is a durable, project-based model serving pharma, biotech and academic research. Specialized mass‑spectrometry capabilities create repeatable project revenue streams tied to drug discovery and biomarker workflows, supporting stable demand over 2–6 months.
Negative Factors
Declining revenue and negative gross profit
A multi-year swing from earlier profitability to persistent revenue decline and negative gross profit indicates weak demand coverage and poor fixed cost absorption. Continued operating losses erode reserves and limit ability to reinvest in sales, R&D or scale proprietary products without external funding.
Read all positive and negative factors
Positive Factors
Negative Factors
Specialized proteomics services
The company’s core fee-for-service proteomics business is a durable, project-based model serving pharma, biotech and academic research. Specialized mass‑spectrometry capabilities create repeatable project revenue streams tied to drug discovery and biomarker workflows, supporting stable demand over 2–6 months.
Read all positive factors

Proteome Sciences (PRM) vs. iShares MSCI United Kingdom ETF (EWC)

Proteome Sciences Business Overview & Revenue Model

Company Description
Proteome Sciences plc provides contract research services for the identification, validation, and application of protein biomarkers in the United States, the United Kingdom, European Union, and internationally. The company offers TMT LC-MS2, a sta...
How the Company Makes Money
Proteome Sciences primarily makes money by providing fee-for-service proteomics and analytical R&D services to external customers. The core revenue stream is contract revenue from studies where clients pay for experimental design support and execu...

Proteome Sciences Financial Statement Overview

Summary
Overall financial health is weak. Revenue declined (~17% YoY in 2025), gross profit turned negative, and operating/net losses remain large and widening. The balance sheet is the biggest risk with rising debt (~15.77M) and deeply negative equity (~-9.53M), implying elevated refinancing/dilution risk; cash flow improved in 2025 but remains slightly negative and historically volatile.
Income Statement
18
Very Negative
Balance Sheet
12
Very Negative
Cash Flow
26
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue3.76M4.89M5.03M7.78M5.12M
Gross Profit-1.01M-167.00K1.16M4.77M2.96M
EBITDA-1.74M-1.52M-1.14M2.13M625.00K
Net Income-3.06M-3.41M-2.44M1.32M72.00K
Balance Sheet
Total Assets8.26M9.21M11.46M12.43M10.04M
Cash, Cash Equivalents and Short-Term Investments781.00K1.13M2.03M3.99M2.39M
Total Debt15.77M14.52M13.47M11.91M11.69M
Total Liabilities17.79M15.72M14.52M13.28M12.82M
Stockholders Equity-9.53M-6.52M-3.07M-843.00K-2.77M
Cash Flow
Free Cash Flow-143.00K-1.05M-718.00K2.14B8.80B
Operating Cash Flow-46.00K-826.00K-481.00K3.88B10.52B
Investing Cash Flow-97.00K-224.00K-424.00K-21.67B4.27B
Financing Cash Flow-204.00K151.00K-1.06M-209.00K-400.00K

Proteome Sciences Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.80
Price Trends
50DMA
1.73
Positive
100DMA
1.64
Positive
200DMA
1.88
Negative
Market Momentum
MACD
0.01
Positive
RSI
49.02
Neutral
STOCH
48.89
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:PRM, the sentiment is Negative. The current price of 1.8 is below the 20-day moving average (MA) of 1.84, above the 50-day MA of 1.73, and below the 200-day MA of 1.88, indicating a neutral trend. The MACD of 0.01 indicates Positive momentum. The RSI at 49.02 is Neutral, neither overbought nor oversold. The STOCH value of 48.89 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:PRM.

Proteome Sciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
£6.33M-1.7133.80%-23.14%9.57%
49
Neutral
£18.46M-1.10-1044.57%65.60%74.84%
48
Neutral
£15.34M-0.49-104.73%-56.10%41.10%
46
Neutral
£5.78M-1.52-52.92%34.02%-93.85%
43
Neutral
£6.40M-0.44-409.40%13.88%15.35%
41
Neutral
£5.15M-0.27-138.93%5.41%39.06%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:PRM
Proteome Sciences
1.78
-1.23
-40.83%
GB:CLBX
ANGLE plc
1.38
-4.17
-75.18%
GB:GDR
Genedrive
1.20
0.47
65.29%
GB:OPTI
OptiBiotix Health
5.75
-4.50
-43.90%
GB:VRCI
Verici Dx Plc
0.25
-0.28
-52.38%
GB:GENI
GENinCode UK Ltd.
0.95
-0.55
-36.67%

Proteome Sciences Corporate Events

Business Operations and Strategy
Proteome Sciences Wins New Chemoproteomics Contract Ahead of 2026 Trial Programme
Positive
Jun 22, 2026
Proteome Sciences plc announced that it has secured a significant new clinical contract linked to its target engagement and chemoproteomics platform, which it expects will precede the launch of a new clinical trial programme later in 2026. Managem...
Business Operations and StrategyExecutive/Board Changes
Proteome Sciences Reshapes Scientific Leadership as CSO Moves to Non-Executive Role
Neutral
Jun 1, 2026
Proteome Sciences plc is a specialist provider of contract proteomics services that support drug discovery, development and biomarker identification for pharmaceutical and biotech partners. Using proprietary platforms such as SysQuant®, TMT&#...
Business Operations and StrategyFinancial DisclosuresShareholder Meetings
Proteome Sciences Wins Full Shareholder Backing at AGM
Positive
May 14, 2026
Proteome Sciences plc reported that all resolutions put to shareholders at its annual general meeting on 14 May 2026 were duly passed, including approval of the 2025 financial statements and the remuneration report. Investors also backed the reapp...
Business Operations and StrategyFinancial Disclosures
Proteome Sciences Sees Recovery in Reagent Sales and Strong Proteomics Outlook
Positive
May 14, 2026
Proteome Sciences reported progress in its services business, noting improved order levels and a continuing recovery in sales of its TMT and other reagents in the first half of the year. The company said recent investments over the past two years ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 09, 2026