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Oxford BioDynamics PLC (GB:OBD)
LSE:OBD
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Oxford BioDynamics (OBD) AI Stock Analysis

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GB:OBD

Oxford BioDynamics

(LSE:OBD)

Rating:44Neutral
Price Target:
0.50p
▲(19.05% Upside)
Oxford BioDynamics' overall stock score is primarily impacted by its challenging financial performance, with continuous net losses and negative cash flows posing significant risks. While technical analysis shows some short-term bullish momentum, the negative P/E ratio and lack of dividend yield further weigh down the stock's attractiveness. The absence of earnings call and corporate events data limits additional insights.
Positive Factors
Revenue Growth
A strong revenue growth rate indicates increasing demand for OBD's biomarker tests, suggesting successful market penetration and potential for continued expansion in the biotechnology sector.
Proprietary Technology
The EpiSwitch® platform provides a competitive edge in biomarker identification, enhancing OBD's ability to offer unique, clinically relevant solutions, fostering long-term partnerships and revenue opportunities.
Strategic Collaborations
Strategic partnerships with industry leaders enhance market presence and facilitate revenue growth, providing a stable foundation for long-term business development and innovation in the biotechnology field.
Negative Factors
Financial Challenges
Persistent financial losses and cash flow issues indicate operational inefficiencies and may hinder the company's ability to invest in growth opportunities, posing a risk to long-term sustainability.
Rising Debt Levels
Increasing leverage and a rising debt-to-equity ratio suggest heightened financial risk, potentially limiting OBD's flexibility to navigate market challenges and invest in strategic initiatives.
Low Profit Margins
Low profit margins reflect operational inefficiencies and high costs relative to revenue, which may impede the company's ability to achieve profitability and sustain long-term growth in a competitive market.

Oxford BioDynamics (OBD) vs. iShares MSCI United Kingdom ETF (EWC)

Oxford BioDynamics Business Overview & Revenue Model

Company DescriptionOxford BioDynamics Plc, a biotechnology company, discovers and develops biomarkers for use in the pharmaceutical and biotechnology industry primarily in the United States and internationally. The company provides EpiSwitch, a proprietary technology platform for the discovery, evaluation, validation, and monitoring of epigenetic biomarkers known as chromosome conformation signatures for use in medical testing kits, disease prediction, diagnosis, and treatment. Its products include EpiSwitch CiRT (Checkpoint Inhibitor Response Test), a validated prognostic test for predicting response to checkpoint inhibitor immunotherapy; EpiSwitch CST (Covid Severity Test), an advanced blood test for the prediction of COVID-19 severity in adults; and EpiSwitch Explorer Array Kit for high-resolution 3D genome profiling and biomarker discovery. Oxford BioDynamics Plc was incorporated in 2007 and is headquartered in Oxford, the United Kingdom.
How the Company Makes MoneyOxford BioDynamics generates revenue primarily through the sale of its biomarker tests and services, which are utilized by pharmaceutical companies, research institutions, and healthcare providers. The company's key revenue streams include fees for conducting epigenetic testing and analysis, licensing agreements for its proprietary technology, and collaborations with pharmaceutical companies for the development of companion diagnostics. Additionally, OBD may receive funding through research grants and partnerships aimed at advancing epigenetic research, which further contributes to its earnings. Strategic collaborations with industry leaders enhance its market presence and facilitate revenue growth.

Oxford BioDynamics Financial Statement Overview

Summary
Oxford BioDynamics faces substantial financial challenges with consistent net losses, rising leverage, and negative cash flows. Although there are some assets and equity, these are diminishing, indicating potential liquidity and solvency concerns.
Income Statement
30
Negative
Oxford BioDynamics shows a challenging financial trajectory with consistent net losses over the past years. The gross profit margin is low, and net income has been negative, indicating unprofitability. Revenue growth has been erratic, with no clear upward trend. EBIT and EBITDA margins are negative, reflecting operational inefficiencies and high costs relative to revenue.
Balance Sheet
35
Negative
The balance sheet presents concerns, particularly in rising debt levels relative to equity, which has led to a rising debt-to-equity ratio. Return on equity is negative due to consistent net losses, and the equity ratio has decreased, indicating increased leverage and financial risk. However, there is still some equity cushion available, albeit shrinking.
Cash Flow
40
Negative
Cash flow analysis indicates significant strains with negative free cash flow and operating cash flow over the years. There was a notable decline in free cash flow growth rate, highlighting cash generation issues. Operating cash flow to net income ratio is negative, reinforcing operational cash challenges. Financing activities have been critical in supporting cash needs.
BreakdownTTMSep 2024Sep 2023Sep 2022Sep 2021Sep 2020
Income Statement
Total Revenue617.00K636.00K510.00K154.00K341.00K456.00K
Gross Profit-7.49M289.00K266.00K116.00K-557.00K-166.00K
EBITDA-9.32M-10.27M-9.84M-6.16M-6.43M-4.42M
Net Income-11.11M-11.57M-10.83M-6.71M-6.68M-4.31M
Balance Sheet
Total Assets11.07M12.11M16.13M11.34M15.38M15.35M
Cash, Cash Equivalents and Short-Term Investments1.19M2.83M5.25M999.00K4.34M11.51M
Total Debt6.00M5.74M6.44M6.14M6.59M541.00K
Total Liabilities9.44M7.75M10.07M8.76M8.69M1.77M
Stockholders Equity1.62M4.36M6.05M2.59M6.68M13.56M
Cash Flow
Free Cash Flow-7.46M-10.77M-9.01M-6.08M-9.01M-3.86M
Operating Cash Flow-6.71M-10.17M-8.29M-5.18M-5.92M-3.40M
Investing Cash Flow1.68M-1.49M-691.00K1.25M2.83M4.58M
Financing Cash Flow5.03M8.25M13.42M2.56M-804.00K-181.00K

Oxford BioDynamics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.42
Price Trends
50DMA
0.46
Negative
100DMA
0.42
Negative
200DMA
0.59
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
42.03
Neutral
STOCH
11.11
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:OBD, the sentiment is Negative. The current price of 0.42 is below the 20-day moving average (MA) of 0.47, below the 50-day MA of 0.46, and below the 200-day MA of 0.59, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 42.03 is Neutral, neither overbought nor oversold. The STOCH value of 11.11 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:OBD.

Oxford BioDynamics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
£11.12M-13.85%7.27%39.64%
63
Neutral
£27.37M-137.62%10.50%-9.60%
51
Neutral
$8.02B-0.39-43.38%2.20%22.34%-2.13%
46
Neutral
£29.67M-99.43%17.39%96.02%
44
Neutral
£8.32M-333.59%45.22%55.71%
£43.75M-302.41%
44
Neutral
£18.18M-139.16%72.98%55.36%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:OBD
Oxford BioDynamics
0.42
-4.17
-90.85%
GB:IXI
IXICO plc
12.00
2.50
26.32%
GB:HEMO
HemoGenyx Pharmaceuticals Plc
921.00
250.60
37.38%
GB:FAB
Fusion Antibodies Plc
16.00
12.50
357.14%
GB:AREC
Arecor Therapeutics PLC
72.50
-7.50
-9.38%
GB:APTA
Aptamer Group Plc
1.10
0.86
358.33%

Oxford BioDynamics Corporate Events

Business Operations and StrategyProduct-Related Announcements
Oxford BioDynamics’ EpiSwitch CiRT Test Shows Promise in Clinical Treatment Decisions
Positive
Sep 4, 2025

Oxford BioDynamics has announced interim results from its PROWES trial, showcasing the clinical utility of its EpiSwitch CiRT test in guiding treatment decisions for patients undergoing immune checkpoint inhibitor therapy. The study, published in the journal Cancers, demonstrated that the CiRT test influenced treatment choices in 61% of cases, helping oncologists make more informed decisions. The test’s ability to predict patient responses with high sensitivity and specificity could lead to significant cost savings by avoiding ineffective treatments. The company plans to apply for inclusion in the US National Comprehensive Cancer Network clinical guidelines, aiming for broader adoption and commercial success.

The most recent analyst rating on (GB:OBD) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Oxford BioDynamics Partners with Google Cloud to Advance Genomic Analytics
Positive
Aug 13, 2025

Oxford BioDynamics has announced a collaboration with Google Cloud to enhance its cloud-based analytical frameworks for precision medicine. This partnership will allow OBD to scale its EpiSwitch® platform using Google Cloud’s infrastructure, facilitating high-throughput, AI-powered 3D genomic analytics. The collaboration is expected to improve OBD’s digital transformation, enabling faster insights and broader access for its pharmaceutical and biotech partners, while also creating opportunities for future commercialization of its platform.

Business Operations and Strategy
Oxford BioDynamics Sees Shift in Shareholder Structure
Neutral
Jul 18, 2025

Oxford BioDynamics PLC has announced a significant change in its shareholder structure following the acquisition of financial instruments by Trafalgar Capital Management (HK) Limited. This acquisition has resulted in Trafalgar Capital holding 3.3% of the voting rights in Oxford BioDynamics, marking a notable shift in the company’s ownership landscape. This development could potentially impact the company’s strategic decisions and influence its market position, as it reflects increased interest and investment from international stakeholders.

Business Operations and StrategyProduct-Related Announcements
Oxford BioDynamics and Agilent Technologies to Showcase EpiSwitch 3D Genomic Platform
Positive
Jul 17, 2025

Oxford BioDynamics announced a joint webinar with Agilent Technologies to showcase their EpiSwitch 3D Genomic Platform, which utilizes Agilent’s SureScan microarray to explore 3D genome architecture for disease insights. This collaboration has been crucial in developing accurate and scalable clinical tests, such as the EpiSwitch PSE for prostate cancer detection and the EpiSwitch SCB for diagnosing canine cancers, enhancing the company’s position in precision medicine.

Business Operations and StrategyRegulatory Filings and Compliance
Oxford BioDynamics Announces Change in Major Holdings
Neutral
Jul 17, 2025

Oxford BioDynamics PLC announced a change in major holdings as Spreadex LTD adjusted its financial instruments, resulting in a slight decrease in its overall voting rights in the company. This adjustment reflects a minor shift in stakeholder positions, potentially impacting the company’s governance dynamics and signaling strategic financial maneuvers within the biotechnology sector.

Business Operations and StrategyRegulatory Filings and Compliance
Oxford BioDynamics Announces Change in Major Holdings
Neutral
Jul 15, 2025

Oxford BioDynamics PLC has announced a change in its major holdings, with Spreadex LTD acquiring a significant portion of financial instruments, resulting in a total voting rights percentage of 3.0815%. This acquisition reflects Spreadex’s strategic interest in the company, potentially impacting Oxford BioDynamics’ market positioning and shareholder dynamics.

Business Operations and StrategyProduct-Related Announcements
Oxford BioDynamics’ EpiSwitch Biomarkers Show Promise in Cancer Diagnostics
Positive
Jul 15, 2025

Oxford BioDynamics announced the successful use of its EpiSwitch blood-based biomarkers in a study conducted by Pfizer, which evaluated tumor status and treatment outcomes in cancer patients from the JAVELIN Bladder 100 Trial. The study demonstrated that EpiSwitch biomarkers can effectively determine immune activity levels in tumors, aiding in cancer treatment decisions and potentially revolutionizing cancer detection and monitoring. This advancement underscores the company’s potential for growth in the cancer diagnostics market and highlights the efficacy of its EpiSwitch technology, already proven in prostate cancer testing.

Business Operations and StrategyRegulatory Filings and Compliance
Oxford BioDynamics Announces Changes in Major Holdings
Neutral
Jul 1, 2025

Oxford BioDynamics PLC has announced a change in its major holdings, with Spreadex LTD acquiring or disposing of financial instruments, resulting in a shift in voting rights. This notification reflects a slight decrease in the total percentage of voting rights held by Spreadex, which may influence the company’s shareholder dynamics and strategic decisions moving forward.

Business Operations and StrategyFinancial Disclosures
Oxford BioDynamics Reports Strong Interim Results and Strategic Progress
Positive
Jun 30, 2025

Oxford BioDynamics Plc announced its interim results for the six-month period ending March 31, 2025, highlighting significant corporate and operational achievements. The company reported a substantial increase in revenue and cash reserves, driven by the growth in sales of its EpiSwitch PSE test and strategic agreements, such as the one with Bupa UK. Despite ongoing commercial discussions, no definitive deals have been secured, prompting the company to focus on preserving business integrity and optimizing shareholder value. The company also achieved ISO15189 accreditation for its UK lab and recorded its highest PSE sales in June 2025, indicating strong market acceptance and potential for future growth.

Regulatory Filings and Compliance
Oxford BioDynamics Sees Change in Financial Instrument Holdings
Neutral
Jun 27, 2025

Oxford BioDynamics PLC has announced a change in its financial instrument holdings, as Spreadex LTD has adjusted its position in the company. The notification indicates that Spreadex now holds a total of 3.0049% of the voting rights in Oxford BioDynamics, reflecting a slight increase from its previous position. This adjustment may influence the company’s market dynamics and stakeholder interests as it continues to navigate the competitive landscape of the biotechnology sector.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 10, 2025