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Oxford BioDynamics PLC (GB:OBD)
LSE:OBD

Oxford BioDynamics (OBD) AI Stock Analysis

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GB:OBD

Oxford BioDynamics

(LSE:OBD)

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Underperform 38 (OpenAI - 5.2)
Rating:38Underperform
Price Target:
0.26p
▲(7.92% Upside)
Oxford BioDynamics faces significant financial and technical challenges, with persistent losses, high leverage, and bearish market momentum. The negative P/E ratio and lack of dividend yield further impact the stock's valuation. The overall score reflects these substantial risks, with financial performance being the most critical factor.
Positive Factors
Strong reported revenue growth
Very high reported revenue growth indicates the company is gaining commercial traction with its services and platform. Sustained top-line expansion supports longer-term investment in R&D and partnerships, improving the chance to convert scale into durable recurring revenues.
Proprietary EpiSwitch platform
Owning a proprietary epigenetic biomarker platform creates an enduring competitive advantage: IP protection, differentiated data, and a technological moat. This supports licensing, service revenues, and embedded clinical workflows that can produce sticky, repeatable revenue streams over time.
Partnerships with pharma and academia
Ongoing collaborations provide durable access to validation cohorts, co-development funding, and commercial pathways. Partnerships reduce translational risk, help validate clinical utility, and can produce non-dilutive revenue or licensing deals that materially de-risk commercialization timelines.
Negative Factors
High financial leverage
Very high leverage materially reduces financial flexibility, raising interest burden and refinancing risk. In a capital-intensive biotech model this constrains the firm’s ability to fund R&D or scale commercial activities without stressing liquidity or resorting to dilutive financing.
Persistent negative profitability
Ongoing negative gross and EBIT margins indicate structural cost or pricing issues preventing profitable scaling. Continued losses reduce retained capital for growth, increase reliance on external funding, and may impede long-term partner or payer adoption absent a clear path to margin improvement.
Weak and declining cash flow
Declining free cash flow and negative operating cash flow versus income signal persistent cash burn and limited internal financing capacity. This elevates refinancing risk and can force short-term funding decisions that compromise long-term R&D timelines or commercialization investments.

Oxford BioDynamics (OBD) vs. iShares MSCI United Kingdom ETF (EWC)

Oxford BioDynamics Business Overview & Revenue Model

Company DescriptionOxford BioDynamics Plc, a biotechnology company, discovers and develops biomarkers for use in the pharmaceutical and biotechnology industry primarily in the United States and internationally. The company provides EpiSwitch, a proprietary technology platform for the discovery, evaluation, validation, and monitoring of epigenetic biomarkers known as chromosome conformation signatures for use in medical testing kits, disease prediction, diagnosis, and treatment. Its products include EpiSwitch CiRT (Checkpoint Inhibitor Response Test), a validated prognostic test for predicting response to checkpoint inhibitor immunotherapy; EpiSwitch CST (Covid Severity Test), an advanced blood test for the prediction of COVID-19 severity in adults; and EpiSwitch Explorer Array Kit for high-resolution 3D genome profiling and biomarker discovery. Oxford BioDynamics Plc was incorporated in 2007 and is headquartered in Oxford, the United Kingdom.
How the Company Makes MoneyOxford BioDynamics generates revenue through a combination of biomarker discovery services, partnerships with pharmaceutical and biotechnology companies, and the commercialization of its proprietary EpiSwitch technology. Key revenue streams include contract research services, which provide clients with tailored biomarker analysis and support for drug development; licensing agreements for its EpiSwitch platform, enabling partners to utilize its technology in their own research and diagnostic products; and potential royalties from any commercialized tests developed in collaboration with strategic partners. The company has established collaborations with various academic institutions and industry players, which not only enhance its research capabilities but also create additional revenue opportunities through joint ventures and shared intellectual property.

Oxford BioDynamics Financial Statement Overview

Summary
Oxford BioDynamics is facing significant financial challenges, with persistent losses and high leverage. Despite a revenue growth rate of 22.21%, profitability and cash flow remain critical concerns. The company needs to improve operational efficiency and manage debt levels to enhance financial stability.
Income Statement
30
Negative
Oxford BioDynamics shows a consistent pattern of negative profitability with a net profit margin of -10.19% in the latest year. Despite a revenue growth rate of 22.21%, the company struggles with negative gross and EBIT margins, indicating challenges in managing costs and achieving operational efficiency.
Balance Sheet
25
Negative
The company's balance sheet reveals high leverage with a debt-to-equity ratio of 4.58, indicating significant reliance on debt financing. The return on equity is negative, reflecting ongoing losses and potential risks to equity holders. The equity ratio is low, suggesting limited asset backing by equity.
Cash Flow
35
Negative
Cash flow analysis shows a negative free cash flow growth rate of -33.93% and a high free cash flow to net income ratio of 1.00, indicating that cash flow is closely aligned with net losses. The operating cash flow to net income ratio is negative, highlighting cash flow challenges.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue1.09M1.09M636.00K510.00K154.00K341.00K
Gross Profit-6.15M-6.15M289.00K266.00K116.00K-557.00K
EBITDA-9.80M-9.80M-10.27M-9.84M-6.16M-6.43M
Net Income-11.15M-11.15M-11.57M-10.83M-6.71M-6.68M
Balance Sheet
Total Assets8.09M8.09M12.11M16.13M11.34M15.38M
Cash, Cash Equivalents and Short-Term Investments1.39M1.39M2.83M5.25M999.00K4.34M
Total Debt5.11M5.11M5.74M6.44M6.14M6.59M
Total Liabilities6.97M6.97M7.75M10.07M8.76M8.69M
Stockholders Equity1.12M1.12M4.36M6.05M2.59M6.68M
Cash Flow
Free Cash Flow-7.73M-7.73M-10.77M-9.01M-6.08M-9.01M
Operating Cash Flow-7.71M-7.71M-10.17M-8.29M-5.18M-5.92M
Investing Cash Flow756.00K756.00K-1.49M-691.00K1.25M2.83M
Financing Cash Flow6.52M6.52M8.25M13.42M2.56M-804.00K

Oxford BioDynamics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.24
Price Trends
50DMA
0.26
Positive
100DMA
0.34
Negative
200DMA
0.38
Negative
Market Momentum
MACD
<0.01
Negative
RSI
53.86
Neutral
STOCH
44.12
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:OBD, the sentiment is Positive. The current price of 0.24 is below the 20-day moving average (MA) of 0.27, below the 50-day MA of 0.26, and below the 200-day MA of 0.38, indicating a neutral trend. The MACD of <0.01 indicates Negative momentum. The RSI at 53.86 is Neutral, neither overbought nor oversold. The STOCH value of 44.12 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GB:OBD.

Oxford BioDynamics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
£10.43M-6.05-15.57%13.32%55.07%
52
Neutral
£23.60M-6.25-213.66%39.88%81.33%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
£53.08M-62.12-11.24%283.74%78.57%
47
Neutral
£9.60M-3.89-648.46%
44
Neutral
£16.88M-9.38-164.37%-11.43%23.40%
38
Underperform
£11.80M-0.29-407.49%72.17%79.03%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:OBD
Oxford BioDynamics
0.28
-0.28
-50.00%
GB:IXI
IXICO plc
11.25
-1.25
-10.00%
GB:SBTX
SkinBioTherapeutics
20.50
2.88
16.31%
GB:FAB
Fusion Antibodies Plc
13.50
5.90
77.63%
GB:GENF
Genflow Biosciences Plc
1.95
-0.14
-6.49%
GB:APTA
Aptamer Group Plc
0.88
0.46
108.33%

Oxford BioDynamics Corporate Events

Executive/Board ChangesStock BuybackFinancial DisclosuresShareholder Meetings
Oxford BioDynamics AGM Resolutions Passed Amid Shareholder Dissent on Pay and Governance
Neutral
Jan 26, 2026

Oxford BioDynamics announced that all resolutions at its Annual General Meeting were passed, including the approval of financial statements, director elections and re-elections, auditor reappointment, share allotment authorities and the power to buy back its own shares, as well as the disapplication of pre-emption rights for certain capital raisings. However, a significant minority of shareholders opposed the remuneration report and the re-election of non-executive director Dr David Holbrook, prompting the board to commit to further consultation with investors, a move that underscores ongoing shareholder scrutiny of governance and pay at the AIM-listed diagnostics group.

The most recent analyst rating on (GB:OBD) stock is a Hold with a £0.26 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Oxford BioDynamics Board Veteran Steps Down as Major Shareholder Retains Influence
Neutral
Jan 26, 2026

Oxford BioDynamics has announced that long-serving non-executive director Stephen Diggle has stepped down from the board with immediate effect, in line with previously signalled plans and corporate governance practice after nine years in the role. While Diggle departs the board, his firm Vulpes Investment Management remains the company’s largest shareholder and will nominate a new non-executive director in due course, ensuring continued influence over governance and strategic direction at a time when the diagnostics specialist is commercialising its EpiSwitch-based tests and seeking to strengthen its market position.

The most recent analyst rating on (GB:OBD) stock is a Hold with a £0.26 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Financial DisclosuresShareholder Meetings
Oxford BioDynamics Publishes 2025 Annual Report and Sets Date for AGM
Neutral
Dec 22, 2025

Oxford BioDynamics has published its annual report and accounts for the year ended 30 September 2025, making the document available electronically on its website and dispatching hard copies, including the notice of its upcoming annual general meeting, to shareholders. The AGM is scheduled to take place in Oxford on 26 January 2026, providing investors with a formal opportunity to review the company’s performance and strategy as it continues to commercialise and expand its portfolio of precision genomic diagnostic tests.

The most recent analyst rating on (GB:OBD) stock is a Sell with a £0.23 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
Oxford BioDynamics Reports Strong Growth and Strategic Partnerships in 2025
Positive
Dec 16, 2025

Oxford BioDynamics Plc announced its preliminary results for the year ending September 2025, highlighting significant growth in its EpiSwitch® Prostate Screening Test orders and a successful £7 million fundraising effort. The company has made strategic advancements, including a partnership with Google Cloud and ongoing discussions for third-party collaborations, positioning itself for further growth and increased shareholder value.

The most recent analyst rating on (GB:OBD) stock is a Sell with a £0.50 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Financial Disclosures
Oxford BioDynamics to Announce Year-End Financial Results
Neutral
Dec 9, 2025

Oxford BioDynamics Plc announced that it will release its financial results for the year ending 30 September 2025 on 16 December 2025. This announcement highlights the company’s ongoing commitment to transparency and may impact its market positioning by providing stakeholders with insights into its financial health and operational progress.

The most recent analyst rating on (GB:OBD) stock is a Sell with a £0.50 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresProduct-Related Announcements
Oxford BioDynamics Reports Record Sales Amidst Screening Recommendations
Positive
Dec 3, 2025

Oxford BioDynamics Plc announced that the recent UK National Screening Committee’s draft recommendation on prostate cancer screening does not directly affect its EpiSwitch PSE test. Despite this, the company has reported six consecutive months of record sales for the PSE test in the US and private healthcare in the UK, indicating strong market performance and growth potential.

The most recent analyst rating on (GB:OBD) stock is a Sell with a £0.50 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Oxford BioDynamics Grants Significant Share Options to Employees and Directors
Neutral
Nov 10, 2025

Oxford BioDynamics Plc has announced the grant of 170,000,000 options over its ordinary shares to its employees and advisers, including directors and PDMRs. This grant, which is part of the company’s 2016 Employee and Non-Employee Share Option Plans, is set at an exercise price of 0.61p per share, a 100% premium over the previous closing price. The vesting of these options is staggered over a period of up to two years, with some options becoming exercisable immediately and others over the next two years, potentially impacting the company’s stock value and stakeholder interests.

The most recent analyst rating on (GB:OBD) stock is a Sell with a £0.50 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Private Placements and FinancingShareholder Meetings
Oxford BioDynamics Advances with Major Fundraising Initiative
Positive
Nov 7, 2025

Oxford BioDynamics PLC announced the successful passing of resolutions at its General Meeting, which facilitates the issuance of over 2.3 billion new ordinary shares as part of a significant fundraising effort. This move is expected to enhance the company’s trading position on AIM and increase its total voting rights, impacting stakeholders’ interests and potentially strengthening its market presence.

The most recent analyst rating on (GB:OBD) stock is a Sell with a £0.50 price target. To see the full list of analyst forecasts on Oxford BioDynamics stock, see the GB:OBD Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 19, 2025