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Aptamer Group Plc (GB:APTA)
LSE:APTA

Aptamer Group Plc (APTA) AI Stock Analysis

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Aptamer Group Plc

(LSE:APTA)

Rating:54Neutral
Price Target:
0.50p
▲(31.58%Upside)
Aptamer Group Plc's overall stock score is primarily influenced by its challenging financial performance and valuation metrics. However, the positive technical indicators and numerous strategic corporate events provide a counterbalance, suggesting potential growth opportunities in a high-risk environment.

Aptamer Group Plc (APTA) vs. iShares MSCI United Kingdom ETF (EWC)

Aptamer Group Plc Business Overview & Revenue Model

Company DescriptionAptamer Group Plc (APTA) is a biotechnology company specializing in the development and application of aptamer technology. The company operates within the life sciences sector, focusing on the discovery and development of aptamers, which are synthetic molecules that can bind to specific targets such as proteins, cells, and small molecules with high affinity and specificity. Aptamer Group provides custom aptamer discovery and development services for research, diagnostics, and therapeutic applications across various industries including pharmaceuticals, diagnostics, and bio-manufacturing.
How the Company Makes MoneyAptamer Group Plc generates revenue primarily through its custom aptamer discovery and development services. The company collaborates with pharmaceutical and biotechnology companies, offering tailored solutions for the identification and development of aptamers that meet specific client needs. These services are provided under contract research agreements, where clients pay for the discovery and development process. Additionally, Aptamer Group may license its aptamer technology to other companies, receiving licensing fees and potential milestone payments. The company's strategic partnerships and collaborations with industry leaders also contribute to its revenue streams, enabling joint development projects and expanding the commercial reach of its aptamer technologies.

Aptamer Group Plc Financial Statement Overview

Summary
Aptamer Group Plc faces significant financial challenges, with declining revenues and negative profit margins. The company relies on debt, with a debt-to-equity ratio of 0.92, and struggles with negative cash flows, indicating a need for improved cash management and operational efficiency.
Income Statement
35
Negative
Aptamer Group Plc's income statement shows significant challenges in maintaining revenue and profitability. The company has experienced declining revenues and negative profit margins, with a net profit margin of -343.02% and negative EBIT and EBITDA margins. Revenue has decreased by 50.91% compared to the previous year, reflecting a need to improve its revenue-generating strategies.
Balance Sheet
50
Neutral
The balance sheet indicates a moderate level of risk with a debt-to-equity ratio of 0.92, showing reliance on debt financing. The equity ratio stands at 32.02%, which signals some stability. However, the return on equity is negative at -333.71%, highlighting inefficiencies in generating returns from equity.
Cash Flow
40
Negative
Cash flow analysis reveals substantial negative free cash flow, demonstrating cash management challenges. The operating cash flow to net income ratio is 0.77, indicating some alignment between operating cash flow and net income, though both are negative. The company needs to focus on improving cash flow generation.
BreakdownTTMJun 2024Jun 2023Jun 2022Jun 2021Mar 2020
Income Statement
Total Revenue1.22M860.00K1.75M4.04M1.28M854.57K
Gross Profit510.00K250.00K359.00K2.69M538.40K455.97K
EBITDA-2.17M-2.81M-7.36M-2.19M-2.24M-733.59K
Net Income-2.26M-2.96M-7.84M-2.09M-1.85M-674.73K
Balance Sheet
Total Assets4.35M2.77M2.75M11.52M2.06M1.39M
Cash, Cash Equivalents and Short-Term Investments1.97M870.00K234.00K6.69M369.00K293.15K
Total Debt643.00K817.00K69.00K1.31M78.00K160.98K
Total Liabilities1.78M1.88M2.45M3.47M1.96M1.14M
Stockholders Equity2.56M887.00K304.00K8.05M105.00K245.81K
Cash Flow
Free Cash Flow-1.87M-2.41M-6.09M-2.79M-1.26M-243.54K
Operating Cash Flow-1.85M-2.28M-4.06M-2.38M-1.10M-82.71K
Investing Cash Flow-116.00K-122.00K-2.03M-418.00K-339.20K-160.79K
Financing Cash Flow2.18M3.04M-365.00K9.12M1.50M-190.51K

Aptamer Group Plc Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.38
Price Trends
50DMA
0.35
Positive
100DMA
0.33
Positive
200DMA
0.32
Positive
Market Momentum
MACD
0.01
Negative
RSI
60.67
Neutral
STOCH
48.89
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:APTA, the sentiment is Positive. The current price of 0.38 is above the 20-day moving average (MA) of 0.34, above the 50-day MA of 0.35, and above the 200-day MA of 0.32, indicating a bullish trend. The MACD of 0.01 indicates Negative momentum. The RSI at 60.67 is Neutral, neither overbought nor oversold. The STOCH value of 48.89 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GB:APTA.

Aptamer Group Plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
£7.47M-99.43%17.39%96.02%
52
Neutral
$7.53B0.32-61.76%2.28%16.60%1.56%
GBOBD
44
Neutral
£5.09M-333.59%45.22%
GBFAB
44
Neutral
£7.33M-129.49%14.12%78.16%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:APTA
Aptamer Group Plc
0.38
-0.32
-45.71%
GB:OBD
Oxford BioDynamics
0.26
-7.31
-96.57%
GB:FAB
Fusion Antibodies Plc
6.45
3.40
111.48%

Aptamer Group Plc Corporate Events

Private Placements and FinancingBusiness Operations and Strategy
Aptamer Group Raises £2 Million to Boost Optimer® Technology Commercialization
Positive
Jul 4, 2025

Aptamer Group plc has raised £2.0 million through a placing of ordinary shares to accelerate the commercialization of its Optimer® technology and strengthen its market position. The funds will support manufacturing investments, enhance licensing negotiations, and launch new services, including biomarker discovery and AI-driven aptamer development. This capital raise is expected to boost the company’s credibility, improve supply chain reliability, and open new opportunities in the life sciences sector, positioning Aptamer as a global leader in aptamer technology.

Product-Related AnnouncementsBusiness Operations and Strategy
Aptamer Group Advances Liver Fibrosis Treatment with Optimer® Breakthrough
Positive
Jun 30, 2025

Aptamer Group plc has announced a significant breakthrough in its liver fibrosis treatment program using its Optimer® platform. The company has identified a novel molecular target that enhances the platform’s potential to deliver targeted gene therapy to liver cells responsible for scarring. This advancement positions Aptamer for strategic licensing discussions with pharmaceutical partners, addressing a critical unmet need in the $20 billion fibrosis market. The Optimer® platform, acting like a ‘magic bullet’, targets scarred liver cells to deliver siRNA, potentially reducing or reversing fibrosis. Laboratory tests have shown promising results, and Aptamer is planning in vivo studies to further evaluate the platform’s efficacy and safety, paving the way for human trials and strategic collaborations.

Product-Related AnnouncementsBusiness Operations and Strategy
Aptamer Group Enters Strategic Partnership to Develop Optimer®-Fc Reagent
Positive
Jun 25, 2025

Aptamer Group plc has entered into a development and licensing agreement with a major global life sciences company to create a custom Optimer®-Fc reagent for immunohistochemistry assays and diagnostic kits. This partnership, which includes a royalty structure, is expected to enhance Aptamer’s recurring revenue potential and expand the application of its Optimer platform in high-value life sciences markets, highlighting the commercial potential and technical capabilities of its technology.

Product-Related AnnouncementsBusiness Operations and Strategy
Aptamer Group Expands Collaboration with Unilever for New Odour Control Solutions
Positive
May 30, 2025

Aptamer Group plc has signed a second development agreement with Unilever to create a new panel of Optimer binders targeting body odour pathways. This collaboration, which follows a successful initial programme, positions Aptamer to expand its presence in the personal care sector, leveraging Unilever’s significant market share and the projected growth of the deodorant market.

Product-Related AnnouncementsBusiness Operations and Strategy
Aptamer Group Unveils Promising Data on Optimer Platform for Fibrotic Diseases
Positive
May 15, 2025

Aptamer Group plc has announced new data on its Optimer therapeutic delivery vehicle, which shows promise for treating liver fibrosis and other fibrotic conditions. Presented at the ASGCT Annual Meeting, the data highlights the platform’s adaptability and potential for broad therapeutic application, positioning it as a significant player in the multi-billion-dollar market for fibrotic disease treatments. The collaboration with AstraZeneca and interest from multiple pharmaceutical companies suggest strong future commercial opportunities.

Business Operations and Strategy
Aptamer Group Secures New Contracts and Licensing Agreements, Boosting Growth
Positive
May 15, 2025

Aptamer Group plc has announced two new development contracts with existing customers, valued at up to £231,000, highlighting the growing commercial traction of its Optimer platform. The company has also entered into licensing agreements with a global enzyme provider, which include milestone payments and royalties, further expanding its revenue streams and reinforcing its strategic focus on sustainable growth. These agreements reflect Aptamer’s increasing influence in the life sciences sector and its commitment to long-term value creation.

Product-Related AnnouncementsBusiness Operations and Strategy
Aptamer Group Advances Alzheimer’s Test with New ELISA Format and Royalty Agreement
Positive
May 6, 2025

Aptamer Group plc has successfully adapted its Optimer-based Alzheimer’s disease test into an ELISA format, enhancing its potential for commercialization in hospital laboratories. The company has also secured a royalty agreement with Neuro-Bio Ltd, allowing it to receive royalties on sales of the diagnostic test. This development is part of a strategic effort to capitalize on the $8.3 billion Alzheimer’s diagnostic market, which is expected to grow significantly. The new test format, which uses non-invasive saliva sampling, promises to improve accessibility and speed up diagnosis, potentially transforming the market by addressing a major unmet clinical need.

Product-Related AnnouncementsBusiness Operations and Strategy
Aptamer Group Enters Licensing Deal for Swine Vaccine Adjuvants
Positive
Apr 30, 2025

Aptamer Group plc has entered a global licensing agreement with the University of Glasgow to commercialize Optimer binders as vaccine adjuvants in the swine health sector. This partnership allows Aptamer to tap into the $1.75 billion global swine vaccine market, with the University leading product development and commercialization expected within 12 months. Aptamer will earn a 10% royalty on sales, creating a scalable revenue stream and reinforcing its strategy to leverage its proprietary platform across multiple verticals.

Product-Related AnnouncementsBusiness Operations and Strategy
Aptamer Group Unveils Breakthrough in Targeted Gene Therapy for Liver Fibrosis
Positive
Apr 29, 2025

Aptamer Group plc announced its presentation of new data on the Optimer® delivery vehicle at the 2025 ASGCT Annual Meeting. The data highlights the vehicle’s precision-targeting capabilities for fibrotic liver disease, addressing critical barriers in RNAi drug development by enabling targeted delivery of RNAi therapies to activated hepatic stellate cells. This advancement could enhance therapeutic efficacy, reduce off-target effects, and expand the clinical utility of gene therapies, marking a significant step forward in the treatment of chronic diseases.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 04, 2025