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Aptamer Group Plc (GB:APTA)
LSE:APTA

Aptamer Group Plc (APTA) AI Stock Analysis

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GB:APTA

Aptamer Group Plc

(LSE:APTA)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
1.00p
▲(25.00% Upside)
The score is held back primarily by very weak financial performance (sharp revenue decline, ongoing losses, and negative cash flows). Technicals are the main offset, showing a clear uptrend with supportive momentum. Valuation remains constrained by unprofitability and the absence of dividend information.
Positive Factors
Improved Leverage Management
Improved leverage management enhances financial stability, reducing risk and potentially lowering borrowing costs, which supports long-term growth.
Strategic Collaborations
Strategic collaborations provide revenue stability and growth opportunities, leveraging Aptamer's technology in diverse applications, strengthening market position.
Innovative Technology
Aptamer's innovative aptamer-based technologies provide a competitive edge, driving demand in diagnostics and therapeutics, supporting long-term revenue growth.
Negative Factors
Severe Revenue Decline
A significant revenue decline indicates challenges in market demand or execution, impacting financial health and limiting resources for growth initiatives.
Negative Cash Flow
Negative cash flows strain financial resources, limiting the company's ability to invest in growth and innovation, potentially impacting long-term sustainability.
Ongoing Losses
Ongoing losses reflect operational inefficiencies and market challenges, hindering profitability and potentially affecting investor confidence over time.

Aptamer Group Plc (APTA) vs. iShares MSCI United Kingdom ETF (EWC)

Aptamer Group Plc Business Overview & Revenue Model

Company DescriptionAptamer Group Plc (APTA) is a biotechnology company that specializes in the development of novel aptamer-based technologies for various applications in diagnostics, therapeutics, and research. The company operates primarily in the life sciences sector, focusing on providing high-quality, synthetic aptamers—short, single-stranded oligonucleotides that can bind to specific target molecules. Aptamer Group's core products and services include the design and production of aptamers for use in pharmaceutical development, as well as tools for biomarker discovery and diagnostics.
How the Company Makes MoneyAptamer Group Plc generates revenue through several key streams. Primarily, the company earns income by providing custom aptamer discovery services to pharmaceutical and biotech companies, which are looking for specific binding agents for their drug development processes. Additionally, the company may generate revenue from partnerships and collaborations with industry players that leverage its aptamer technology for research and development purposes. These partnerships often involve upfront payments and milestone payments tied to the progress of joint projects. Furthermore, Aptamer Group may also sell its proprietary aptamer products directly to customers in the diagnostics and life sciences sectors, contributing to its revenue. Overall, the company's financial success is supported by its innovative technology, strategic collaborations, and a growing demand for aptamer-based solutions in the biotechnology industry.

Aptamer Group Plc Financial Statement Overview

Summary
Aptamer Group Plc is facing significant financial challenges, with declining revenues, negative profit margins, and negative cash flows. The company is heavily reliant on debt financing and shows inefficiencies in generating returns from equity.
Income Statement
Aptamer Group Plc's income statement shows significant challenges in maintaining revenue and profitability. The company has experienced declining revenues and negative profit margins, with a net profit margin of -343.02% and negative EBIT and EBITDA margins. Revenue has decreased by 50.91% compared to the previous year, reflecting a need to improve its revenue-generating strategies.
Balance Sheet
The balance sheet indicates a moderate level of risk with a debt-to-equity ratio of 0.92, showing reliance on debt financing. The equity ratio stands at 32.02%, which signals some stability. However, the return on equity is negative at -333.71%, highlighting inefficiencies in generating returns from equity.
Cash Flow
Cash flow analysis reveals substantial negative free cash flow, demonstrating cash management challenges. The operating cash flow to net income ratio is 0.77, indicating some alignment between operating cash flow and net income, though both are negative. The company needs to focus on improving cash flow generation.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.20M1.20M860.00K1.75M4.04M1.28M
Gross Profit465.00K350.00K250.00K359.00K2.69M538.40K
EBITDA-2.33M-2.28M-2.81M-7.36M-2.19M-2.24M
Net Income-2.42M-2.42M-2.96M-7.84M-2.09M-1.85M
Balance Sheet
Total Assets2.83M2.83M2.77M2.75M11.52M2.06M
Cash, Cash Equivalents and Short-Term Investments1.06M1.06M870.00K234.00K6.69M369.00K
Total Debt491.00K491.00K817.00K1.08M1.31M78.00K
Total Liabilities1.45M1.45M1.88M2.45M3.47M1.96M
Stockholders Equity1.38M1.38M887.00K304.00K8.05M105.00K
Cash Flow
Free Cash Flow-1.98M-2.01M-2.41M-6.09M-2.79M-1.26M
Operating Cash Flow-1.97M-2.00M-2.28M-4.06M-2.38M-1.10M
Investing Cash Flow-92.00K-92.00K-122.00K-2.03M-418.00K-339.20K
Financing Cash Flow2.28M2.28M3.04M-365.00K9.12M1.50M

Aptamer Group Plc Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.80
Price Trends
50DMA
0.88
Positive
100DMA
0.91
Positive
200DMA
0.63
Positive
Market Momentum
MACD
0.05
Negative
RSI
56.34
Neutral
STOCH
47.94
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:APTA, the sentiment is Positive. The current price of 0.8 is below the 20-day moving average (MA) of 0.92, below the 50-day MA of 0.88, and above the 200-day MA of 0.63, indicating a bullish trend. The MACD of 0.05 indicates Negative momentum. The RSI at 56.34 is Neutral, neither overbought nor oversold. The STOCH value of 47.94 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GB:APTA.

Aptamer Group Plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
£26.30M-6.96-213.66%39.88%81.33%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
£17.05M-10.42-164.37%-11.43%23.40%
43
Neutral
£6.14M-5.54-433.59%
43
Neutral
£37.52M-2.80-609.30%
41
Neutral
£2.90M-0.27418.49%27.86%
38
Underperform
£10.43M-0.26-407.49%72.17%79.03%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:APTA
Aptamer Group Plc
0.98
0.65
195.45%
GB:OBD
Oxford BioDynamics
0.24
-0.67
-73.30%
GB:CIZ
Cizzle Biotechnology Holdings PLC
1.55
-0.35
-18.42%
GB:HEMO
HemoGenyx Pharmaceuticals Plc
621.00
228.50
58.22%
GB:VAL
ValiRx plc
0.39
-0.29
-42.22%
GB:FAB
Fusion Antibodies Plc
15.00
5.90
64.84%

Aptamer Group Plc Corporate Events

Business Operations and StrategyProduct-Related Announcements
Aptamer Group Secures Second Enzyme-Modulation Licence with Alphazyme for Hot-Start PCR Optimer
Positive
Dec 23, 2025

Aptamer Group has signed a non-exclusive worldwide OEM licensing agreement with Alphazyme, a Maravai LifeSciences company, for an enzyme‑modulating Optimer® used in hot‑start PCR and next-generation sequencing applications. The deal, which follows a successful development programme completed in late 2024, includes royalties on Alphazyme’s product sales, milestone payments, and a supply agreement under which Aptamer will manufacture the Optimer®, creating additional revenue streams and supply-chain leverage. The Optimer® binder enables temperature‑sensitive control of key enzyme activities and can replace two traditional antibodies with a single molecule, offering performance and cost advantages; this second enzyme‑modulation licence with Alphazyme is presented by Aptamer as a commercial and technical validation of its Optimer® platform and is expected to support further licensing opportunities and expansion of both companies’ product portfolios.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.77 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Business Operations and Strategy
Aptamer Group Partners with Twist Bioscience for NGS Market Expansion
Positive
Dec 16, 2025

Aptamer Group plc has entered into a non-exclusive licensing agreement with Twist Bioscience, a leader in synthetic biology and genomics, to commercialize its Optimer® binder technology in the next-generation sequencing (NGS) market. This partnership allows Aptamer to supply its proprietary binders to Twist Bioscience, maximizing the value of its intellectual property and enabling participation in the growing NGS market, projected to reach $23.6 billion by 2029. The agreement supports Aptamer’s strategy of building a licensing-led revenue model, providing sustainable income through upfront payments and royalties, while enhancing its market position alongside a proven industry leader.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Aptamer Group PLC Reports Strong Commercial Momentum and Strategic Progress
Positive
Nov 27, 2025

Aptamer Group PLC has reported significant commercial momentum and strategic progress, highlighted by contract wins with major pharmaceutical companies, resulting in a robust order book for FY26. The company has launched a Biomarker Discovery Service to enhance revenue streams and has raised £1.8 million to support operational expansion. With a focus on licensing deals and intellectual property retention, Aptamer is well-positioned for future growth and shareholder value enhancement.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Business Operations and Strategy
Aptamer Group Secures Key Contracts, Strengthening Commercial Momentum
Positive
Nov 14, 2025

Aptamer Group plc has announced significant contract wins totaling £192,000, contributing to a robust FY26 order book of £1.95 million. These contracts, including a repeat engagement with a top 5 global pharmaceutical company, highlight the company’s growing commercial momentum and the validation of its Optimer® technology. The company’s strategy of securing fee-for-service contracts while building a valuable intellectual property portfolio is proving successful, positioning Aptamer for long-term value through licensing and royalties. With strong demand from top-tier pharmaceutical companies and a replenished sales pipeline, Aptamer is confident in exceeding last year’s revenue and advancing towards therapeutic partnerships.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Business Operations and Strategy
Aptamer Group Secures Major Contract with Top Pharmaceutical Partner
Positive
Nov 4, 2025

Aptamer Group has secured a significant new contract with a top five pharmaceutical company, valued at up to £617,000, marking the third project with this partner. This contract highlights the commercial validation and increasing traction of Aptamer’s Optimer® technology platform, as it will develop binders against three key drug targets. The company retains full intellectual property rights, opening future licensing revenue opportunities. With a 46% increase in contract value visibility compared to last year, Aptamer is well-positioned for sustained revenue growth, reinforcing its foundation of repeat business with leading pharmaceutical partners.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Financial DisclosuresShareholder Meetings
Aptamer Group Announces 2025 AGM and Annual Report Release
Neutral
Nov 3, 2025

Aptamer Group plc has announced the posting of its Annual Report and Accounts for the year ending 30 June 2025, along with the Notice of its 2025 Annual General Meeting (AGM) to shareholders. The AGM is scheduled for 27 November 2025 and will be held in person, with results of voting to be announced to the London Stock Exchange and published on the company’s website.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
Aptamer Group Achieves Significant Growth and Expands Licensing Portfolio
Positive
Oct 14, 2025

Aptamer Group plc reported significant commercial progress for the year ended June 30, 2025, with a 40% revenue increase driven by repeat business from major pharmaceutical companies. The company expanded its Optimer® licensing portfolio from four to eleven assets and secured royalty agreements with Neuro-Bio and the University of Glasgow. Post-period developments include successful fundraising, securing new contracts, and launching a biomarker discovery service, positioning Aptamer for growth and long-term shareholder value.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Aptamer Group Secures New Contract with Top 10 Pharma, Boosting Optimer® Platform Momentum
Positive
Oct 13, 2025

Aptamer Group plc has secured a £112,000 contract with a top 10 global pharmaceutical company to develop Optimer® binders for biomarker research. This contract, part of a series of recent successes, enhances revenue visibility and underscores the growing adoption of the Optimer® platform, positioning the company for continued commercial advancement with a robust pipeline of opportunities.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Financial Disclosures
Aptamer Group to Announce Full Year Results and Host Investor Presentation
Neutral
Oct 10, 2025

Aptamer Group plc announced it will release its full year results for the year ending 30 June 2025 on 14 October 2025. The company will host an online briefing for analysts and an investor presentation on the same day, providing a platform for stakeholders to engage with the company’s leadership and gain insights into its financial performance and strategic direction.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
Aptamer Group Secures Major Contract in Targeted Radiopharmaceuticals
Positive
Oct 8, 2025

Aptamer Group has secured a significant £360,000 contract with a top 3 global pharmaceutical company to develop Optimer® binders for targeted radiopharmaceuticals, with potential applications in therapeutics. This contract marks a strategic expansion into the $7.5 billion targeted radiopharmaceuticals market and positions the company for future licensing and royalty revenue streams. Additionally, Aptamer has secured £665,000 in new contracts and project extensions, including work with a top 5 pharmaceutical company and a therapeutic agreement with Invizius. These developments contribute to a robust sales pipeline of £3.4 million and provide Aptamer with a strong platform for revenue growth in the current financial year.

The most recent analyst rating on (GB:APTA) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on Aptamer Group Plc stock, see the GB:APTA Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 25, 2025