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ANGLE plc (GB:CLBX)
:CLBX
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ANGLE plc (CLBX) AI Stock Analysis

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ANGLE plc (CLBX) vs. iShares MSCI United Kingdom ETF (EWC)

ANGLE plc Business Overview & Revenue Model

Company DescriptionANGLE plc (CLBX) is a biotechnology company specializing in the development of innovative liquid biopsy technologies for early cancer detection and monitoring. The company's flagship product is the Parsortix system, which enables the isolation and harvesting of circulating tumor cells (CTCs) from blood samples. ANGLE operates in the healthcare sector, focusing on oncology diagnostics and research applications, aiming to improve patient outcomes through non-invasive testing methods.
How the Company Makes MoneyANGLE generates revenue primarily through the sale of its Parsortix systems and related consumables. The company also earns income from service contracts and collaborations with research institutions and pharmaceutical companies that utilize its technology for clinical trials and research purposes. Additionally, ANGLE may receive funding through grants and partnerships aimed at advancing its technologies and expanding its market reach. The growth of its revenue is supported by increasing demand for non-invasive cancer diagnostics, strategic partnerships, and the ongoing development and commercialization of new applications for its liquid biopsy technologies.

ANGLE plc Financial Statement Overview

Summary
ANGLE plc faces significant financial challenges with declining revenues and persistent losses. The income statement shows negative revenue growth and profitability metrics, while the balance sheet indicates moderate stability but a negative return on equity. Cash flow issues further exacerbate the financial strain, highlighting liquidity problems and insufficient cash generation.
Income Statement
ANGLE plc's income statement reveals significant challenges. The company has experienced negative revenue growth in the TTM period, with a decline of 4.34%. Profitability metrics are concerning, with a negative net profit margin of -4.97% and a negative EBIT margin of -5.27%. These figures indicate ongoing operational inefficiencies and a struggle to achieve profitability.
Balance Sheet
The balance sheet shows moderate financial stability. The debt-to-equity ratio is relatively low at 0.23, suggesting manageable leverage. However, the return on equity is negative at -104.73%, indicating that the company is not generating returns for its shareholders. The equity ratio stands at 64.67%, reflecting a reasonable proportion of equity financing.
Cash Flow
Cash flow analysis highlights liquidity issues. The operating cash flow to net income ratio is negative, indicating cash outflows exceed net income. Free cash flow growth is negative at -8.73% in the TTM period, and the free cash flow to net income ratio is slightly above 1, suggesting limited cash generation relative to net losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue2.62M2.86M2.19M1.04M1.01M762.00K
Gross Profit1.63M1.78M-408.00K613.00K711.00K597.00K
EBITDA-15.60M-13.02M-19.48M-22.06M-15.74M-12.29M
Net Income-15.78M-14.22M-20.13M-21.69M-15.01M-11.61M
Balance Sheet
Total Assets18.08M25.46M31.18M49.87M47.31M39.05M
Cash, Cash Equivalents and Short-Term Investments5.27M10.43M16.22M31.90M31.84M28.62M
Total Debt3.67M4.21M4.55M5.00M2.34M1.36M
Total Liabilities6.39M7.02M8.24M9.80M6.99M4.71M
Stockholders Equity11.69M18.44M22.94M40.06M40.33M34.34M
Cash Flow
Free Cash Flow-11.62M-13.89M-15.12M-17.94M-15.80M-8.35M
Operating Cash Flow-11.25M-13.45M-14.46M-16.05M-14.01M-7.85M
Investing Cash Flow-491.50K-48.00K-203.00K-1.75M14.77M-1.97M
Financing Cash Flow-2.05M7.67M-1.13M18.10M18.99M18.14M

ANGLE plc Technical Analysis

Technical Analysis Sentiment
Last Price
Price Trends
50DMA
100DMA
200DMA
Market Momentum
MACD
RSI
STOCH
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:CLBX, the sentiment is undefined. The current price of undefined is equal to the 20-day moving average (MA) of ―, equal to the 50-day MA of ―, and equal to the 200-day MA of ―, indicating a neutral trend. The MACD of ― indicates undefined momentum. The RSI at ― is undefined, neither overbought nor oversold. The STOCH value of ― is undefined, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a undefined sentiment for GB:CLBX.

ANGLE plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison

ANGLE plc Corporate Events

Delistings and Listing ChangesPrivate Placements and Financing
CelLBxHealth Announces Update on Fundraising Shares Admission
Positive
Nov 25, 2025

CelLBxHealth plc announced an update regarding the admission of fundraising shares following an oversubscribed placing. The first tranche of 9,090,000 shares is expected to be admitted on December 16, 2025, with a second tranche of up to 770,910,000 shares expected by December 18, 2025. This development is significant for the company’s operations as it reflects strong investor interest and could enhance its market positioning by increasing capital for further advancements in its CTC solutions.

The most recent analyst rating on (GB:CLBX) stock is a Hold with a £1.50 price target. To see the full list of analyst forecasts on ANGLE plc stock, see the GB:CLBX Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
CelLBxHealth plc Completes Oversubscribed Fundraising to Enhance Market Position
Positive
Nov 25, 2025

CelLBxHealth plc has successfully concluded an oversubscribed placing and subscription, raising approximately £6.8 million through the issuance of new shares at a discounted price. This fundraising effort is aimed at expanding the company’s operations, subject to shareholder approval at an upcoming General Meeting. The company plans to launch a Retail Offer to raise an additional £1.0 million, providing existing retail investors an opportunity to participate. The successful fundraising is expected to bolster CelLBxHealth’s market position and support its strategic initiatives in the precision CTC intelligence industry.

The most recent analyst rating on (GB:CLBX) stock is a Hold with a £1.50 price target. To see the full list of analyst forecasts on ANGLE plc stock, see the GB:CLBX Stock Forecast page.

Business Operations and StrategyPrivate Placements and FinancingShareholder Meetings
CelLBxHealth Launches Retail Share Offer to Boost Funding
Neutral
Nov 25, 2025

CelLBxHealth plc, a company focusing on healthcare solutions, has announced a retail offer of new ordinary shares at a discounted issue price of 1.0 pence per share. This offer is part of a larger fundraising initiative that includes a conditional placing and subscriptions, aimed at raising funds for research, sales, restructuring, IT systems, and operating costs. The retail offer is open to existing shareholders in the UK and is conditional on shareholder approval at a general meeting. The initiative reflects the company’s strategy to involve retail shareholders and optimize its financial structure.

The most recent analyst rating on (GB:CLBX) stock is a Hold with a £1.50 price target. To see the full list of analyst forecasts on ANGLE plc stock, see the GB:CLBX Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
CelLBxHealth Announces £6.8 Million Fundraising to Drive Commercial Strategy
Positive
Nov 24, 2025

CelLBxHealth plc has announced a proposed fundraising of £6.8 million through a placing, subscription, and retail offer to support its revised business strategy. The company aims to transition from a research-focused organization to a commercially-driven model, leveraging strategic partnerships with multinational diagnostic companies to expand the adoption of its Parsortix® platform. The fundraising will facilitate the pursuit of commercial milestones, restructuring efforts, and the development of new CTC-based assays, positioning the company for future profitability and integration of CTCs into routine clinical practice.

The most recent analyst rating on (GB:CLBX) stock is a Hold with a £1.50 price target. To see the full list of analyst forecasts on ANGLE plc stock, see the GB:CLBX Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
CelLBxHealth Partners with QIAGEN to Enhance CTC-Based Research
Positive
Nov 18, 2025

CelLBxHealth plc has announced a collaboration and co-marketing agreement with QIAGEN Manchester Ltd. to advance CTC-based research. This partnership will combine CelLBxHealth’s Parsortix platform with QIAGEN’s molecular technologies to enhance drug development programs, biomarker discovery, and companion diagnostic feasibility studies. The agreement allows QIAGEN to offer the Parsortix platform to its pharmaceutical partners, potentially accelerating the adoption of liquid biopsy-based approaches in oncology drug development. This collaboration aligns with CelLBxHealth’s strategy to broaden access to its CTC technology and expand its role in precision medicine.

The most recent analyst rating on (GB:CLBX) stock is a Hold with a £1.50 price target. To see the full list of analyst forecasts on ANGLE plc stock, see the GB:CLBX Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
CelLBxHealth plc Announces £6 Million Fundraising Initiative
Neutral
Nov 5, 2025

CelLBxHealth plc has announced its intention to raise approximately £6 million to extend its cash runway into early 2026. The company is in discussions with shareholders and plans to make an offer to retail investors alongside an institutional placing, with an announcement expected by early December. This fundraising effort is crucial for maintaining its operations and continuing its strategic initiatives in the CTC intelligence industry.

The most recent analyst rating on (GB:CLBX) stock is a Hold with a £2.00 price target. To see the full list of analyst forecasts on ANGLE plc stock, see the GB:CLBX Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
CelLBxHealth Unveils Promising Study on CTC Integration with Roche’s Diagnostic Platform
Positive
Nov 5, 2025

CelLBxHealth plc has announced a successful proof-of-concept study demonstrating the compatibility of its Parsortix platform with Roche Tissue Diagnostics’ BenchMark ULTRA automated staining system. This study, presented at the World ADC Conference, highlights the potential of combining CelLBxHealth’s technology with Roche’s platform for improved cancer biomarker analysis. The integration of CTC-based biomarker assessment into antibody-drug conjugate (ADC) development could optimize patient selection and improve treatment outcomes, addressing the growing demand for targeted cancer therapies. The findings underscore the importance of CTCs as dynamic biomarkers in oncology, offering a safer and more efficient alternative to traditional tissue biopsies.

The most recent analyst rating on (GB:CLBX) stock is a Sell with a £2.00 price target. To see the full list of analyst forecasts on ANGLE plc stock, see the GB:CLBX Stock Forecast page.

Business Operations and StrategyPrivate Placements and FinancingProduct-Related Announcements
CelLBxHealth’s Parsortix® Platform Recognized as Leading Technology in CTC Analysis
Positive
Nov 4, 2025

CelLBxHealth plc announced a major international expert consensus highlighting the clinical relevance of circulating tumor cell (CTC) analysis in cancer management, with the Parsortix® platform identified as a leading next-generation technology. The consensus, published in the European Journal of Cancer, suggests that CTCs provide unique insights not captured by circulating tumor DNA and are expected to become routine in clinical practice within five years, supporting their use in metastatic cancer. This strengthens the foundation for clinical adoption of CTC-based technologies, aligning with CelLBxHealth’s mission to advance precision oncology. Additionally, the company is seeking to raise approximately £6 million to support its operations and engage with shareholders and potential investors.

The most recent analyst rating on (GB:CLBX) stock is a Sell with a £2.00 price target. To see the full list of analyst forecasts on ANGLE plc stock, see the GB:CLBX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―