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Proteome Sciences PLC (GB:PRM)
LSE:PRM
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Proteome Sciences (PRM) AI Stock Analysis

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GB:PRM

Proteome Sciences

(LSE:PRM)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
1.50 p
▼(-47.37% Downside)
Action:ReiteratedDate:05/02/26
The score is primarily pressured by weak financial performance, especially the strained balance sheet (high debt and deeply negative equity) and ongoing losses. Technicals are mixed with only a modest near-term rebound and negative MACD, while valuation is constrained by negative earnings and no provided dividend yield.
Positive Factors
Specialized proteomics capability
Proteome Sciences' core technical capabilities in proteomics and mass spectrometry are highly specialized, creating durable scientific barriers to entry. These capabilities align with drug discovery needs, supporting repeat engagements, technical differentiation, and long-term client reliance on expert analytical services.
Negative Factors
Strained balance sheet
Debt materially exceeds assets and equity is deeply negative, indicating a capital structure under severe strain. This raises refinancing and solvency risk, limits financial flexibility for investment or working capital, and increases the probability of shareholder dilution or covenant constraints.
Read all positive and negative factors
Positive Factors
Negative Factors
Specialized proteomics capability
Proteome Sciences' core technical capabilities in proteomics and mass spectrometry are highly specialized, creating durable scientific barriers to entry. These capabilities align with drug discovery needs, supporting repeat engagements, technical differentiation, and long-term client reliance on expert analytical services.
Read all positive factors

Proteome Sciences (PRM) vs. iShares MSCI United Kingdom ETF (EWC)

Proteome Sciences Business Overview & Revenue Model

Company Description
Proteome Sciences plc provides contract research services for the identification, validation, and application of protein biomarkers in the United States, the United Kingdom, and European Union. The company offers SysQuant provides comprehensive an...
How the Company Makes Money
Proteome Sciences makes money primarily by selling proteomics and mass spectrometry–based contract research and analytical services. Revenue is generated when customers (typically pharma/biotech companies and research institutions) pay for project...

Proteome Sciences Financial Statement Overview

Summary
Financial strength is weak: revenue declined (~17% YoY to ~3.76M) with negative gross profit, operating losses remained large (EBIT ~-2.67M) and net losses widened (~-3.06M). The balance sheet is the biggest risk with rising debt (~15.77M) and deeply negative equity (~-9.53M), implying high refinancing/dilution risk. Cash burn improved in 2025 (FCF ~-0.14M vs ~-1.05M in 2024) but remains negative and volatile historically.
Income Statement
18
Very Negative
Balance Sheet
12
Very Negative
Cash Flow
26
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue3.76M4.89M5.03M7.78M5.12M
Gross Profit-1.01M-167.00K1.16M4.77M2.96M
EBITDA-1.74M-1.44M-986.00K1.89M725.00K
Net Income-3.06M-3.41M-2.44M1.32M72.00K
Balance Sheet
Total Assets8.26M9.21M11.46M12.43M10.04M
Cash, Cash Equivalents and Short-Term Investments781.00K1.13M2.03M3.99M2.39M
Total Debt15.77M14.52M13.47M11.91M11.69M
Total Liabilities17.79M15.72M14.52M13.28M12.82M
Stockholders Equity-9.53M-6.52M-3.07M-843.00K-2.77M
Cash Flow
Free Cash Flow-143.00K-1.05M-718.00K2.14B8.80B
Operating Cash Flow-46.00K-826.00K-481.00K3.88B10.52B
Investing Cash Flow-97.00K-224.00K-424.00K-21.67B4.27B
Financing Cash Flow-204.00K151.00K-1.06M-209.00K-400.00K

Proteome Sciences Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.85
Price Trends
50DMA
1.71
Negative
100DMA
2.09
Negative
200DMA
2.33
Negative
Market Momentum
MACD
-0.08
Positive
RSI
19.34
Positive
STOCH
57.25
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:PRM, the sentiment is Negative. The current price of 2.85 is above the 20-day moving average (MA) of 1.57, above the 50-day MA of 1.71, and above the 200-day MA of 2.33, indicating a bearish trend. The MACD of -0.08 indicates Positive momentum. The RSI at 19.34 is Positive, neither overbought nor oversold. The STOCH value of 57.25 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:PRM.

Proteome Sciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
£7.19M-0.39-122.54%-57.03%-15.71%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
£10.23M-1.31-104.73%29.64%28.51%
47
Neutral
£14.85M-0.76-153.92%65.60%74.84%
43
Neutral
£5.06M-2.61-2.42%102.28%95.58%
42
Neutral
£5.26M-2.4144.15%-23.14%9.57%
40
Underperform
£9.04M-0.47-181.41%12.12%54.24%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:PRM
Proteome Sciences
1.68
-1.06
-38.69%
GB:CLBX
ANGLE plc
0.90
-7.50
-89.29%
GB:GDR
Genedrive
0.95
-0.53
-35.90%
GB:OPTI
OptiBiotix Health
5.10
-14.90
-74.50%
GB:VRCI
Verici Dx Plc
0.48
-1.15
-70.46%
GB:GENI
GENinCode UK Ltd.
1.23
-0.29
-19.41%

Proteome Sciences Corporate Events

Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresPrivate Placements and FinancingProduct-Related AnnouncementsShareholder Meetings
Proteome Sciences Bets on Services Growth and New Tags After TMT Slump
Neutral
Apr 15, 2026
Proteome Sciences reported a sharp decline in 2025 group revenue to £3.76m from £4.89m, as TMT reagent sales and royalties nearly halved due to deep U.S. National Institutes of Health funding cuts, though proteomic services revenue more ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 02, 2026