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Circassia Pharmaceuticals PLC (GB:NIOX)
LSE:NIOX
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Circassia Pharmaceuticals (NIOX) AI Stock Analysis

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GB:NIOX

Circassia Pharmaceuticals

(LSE:NIOX)

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Neutral 67 (OpenAI - 4o)
Rating:67Neutral
Price Target:
76.00p
▲(6.44% Upside)
Circassia Pharmaceuticals' overall stock score is driven primarily by its strong financial performance, characterized by robust revenue growth and cash flow management. The technical analysis indicates a positive trend, though momentum is limited. The high P/E ratio suggests potential overvaluation, partially offset by a decent dividend yield.
Positive Factors
Revenue Growth
Consistent revenue growth indicates a successful market strategy and increased demand for Circassia's products, strengthening its market position.
Cash Flow Management
Strong cash flow management ensures liquidity and financial flexibility, allowing for strategic investments and operational stability.
Financial Stability
A high equity ratio and low debt levels provide a solid financial foundation, reducing risk and supporting long-term growth initiatives.
Negative Factors
Profitability Concerns
Declining net profit margins may indicate challenges in cost management or pricing power, potentially impacting future profitability.
Return on Equity Decline
A declining ROE suggests reduced efficiency in generating profits from shareholders' equity, which could affect investor confidence.
Earnings Volatility
Earnings volatility can create uncertainty and challenge long-term planning, potentially impacting strategic decisions and investor sentiment.

Circassia Pharmaceuticals (NIOX) vs. iShares MSCI United Kingdom ETF (EWC)

Circassia Pharmaceuticals Business Overview & Revenue Model

Company DescriptionCircassia Pharmaceuticals (NIOX) is a specialty pharmaceutical company focused on the development and commercialization of innovative products for respiratory diseases. The company operates primarily in the respiratory sector, with a strong emphasis on asthma and chronic obstructive pulmonary disease (COPD). Circassia's core product offerings include NIOX, a device used for measuring fractional exhaled nitric oxide (FeNO), which aids in the management of asthma by providing insights into airway inflammation and helping healthcare professionals tailor treatment plans.
How the Company Makes MoneyCircassia Pharmaceuticals generates revenue primarily through the sale of its NIOX device and related services to healthcare providers and institutions. The company’s business model is centered on selling its diagnostic products to hospitals, clinics, and physicians, who use the technology to improve asthma management for their patients. In addition to product sales, Circassia may also earn money through partnerships with other pharmaceutical companies for joint marketing or development of new respiratory treatments. Other potential revenue streams may include licensing agreements and collaborations for research and development of new diagnostic tools and treatments in the respiratory field, although specific partnership details and their contributions to overall revenue may vary.

Circassia Pharmaceuticals Financial Statement Overview

Summary
Circassia Pharmaceuticals demonstrates solid financial health with strong revenue growth and robust cash flow management. The company has improved its profitability metrics over the years, although recent fluctuations in net profit margins and ROE warrant attention. The low leverage and high equity position provide a stable financial foundation.
Income Statement
78
Positive
Circassia Pharmaceuticals has demonstrated strong revenue growth over the past years, with a notable increase from $23.9M in 2020 to $41.8M in 2024. The Gross Profit Margin has been consistently high, reaching 72.25% in 2024. However, the Net Profit Margin shows some volatility, having decreased from 29.08% in 2023 to 8.85% in 2024. The company has improved its EBIT Margin from negative values in earlier years to 18.42% in 2024, indicating better operational efficiency.
Balance Sheet
72
Positive
The company maintains a strong equity position with an Equity Ratio of 86.99% in 2024, suggesting financial stability and low reliance on debt. The Debt-to-Equity Ratio is low at 0.03, reflecting prudent financial management. However, the Return on Equity has decreased from 12.76% in 2023 to 6.22% in 2024, signaling a need for improved profitability relative to shareholder equity.
Cash Flow
85
Very Positive
Circassia exhibits robust cash flow management, with Free Cash Flow increasing significantly from $6.6M in 2022 to $16.2M in 2024. The company's Operating Cash Flow to Net Income Ratio is strong at 4.65, indicating efficient conversion of earnings into cash. The Free Cash Flow to Net Income Ratio is favorable at 4.38, highlighting effective cash generation relative to net income.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue46.00M41.80M36.80M31.30M27.90M23.90M
Gross Profit28.50M30.20M26.50M22.20M19.00M16.30M
EBITDA13.70M12.20M8.60M15.20M3.10M-9.10M
Net Income5.20M3.70M10.70M16.10M3.60M-33.50M
Balance Sheet
Total Assets71.00M68.40M91.50M98.50M86.40M103.10M
Cash, Cash Equivalents and Short-Term Investments11.80M10.90M19.90M19.40M12.60M7.40M
Total Debt1.20M1.50M1.10M1.00M1.30M1.60M
Total Liabilities6.60M8.90M7.70M16.60M19.60M37.00M
Stockholders Equity64.40M59.50M83.80M81.90M66.80M66.10M
Cash Flow
Free Cash Flow18.80M16.20M11.30M6.60M1.20M-24.40M
Operating Cash Flow18.70M17.20M11.60M6.70M1.40M-23.90M
Investing Cash Flow-1.40M-1.00M-300.00K-100.00K-200.00K-500.00K
Financing Cash Flow-26.80M-25.10M-10.50M-500.00K4.10M4.30M

Circassia Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price71.40
Price Trends
50DMA
71.49
Positive
100DMA
71.02
Positive
200DMA
68.22
Positive
Market Momentum
MACD
0.31
Negative
RSI
56.33
Neutral
STOCH
55.61
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:NIOX, the sentiment is Positive. The current price of 71.4 is above the 20-day moving average (MA) of 69.74, below the 50-day MA of 71.49, and above the 200-day MA of 68.22, indicating a bullish trend. The MACD of 0.31 indicates Negative momentum. The RSI at 56.33 is Neutral, neither overbought nor oversold. The STOCH value of 55.61 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GB:NIOX.

Circassia Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
67
Neutral
£279.98M53.176.70%3.15%17.95%-54.68%
58
Neutral
£348.05M
56
Neutral
£552.73M4.50%74.32%
54
Neutral
£303.56M8.8215.04%1231.50%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
£769.98M-74.64%55.44%75.77%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:NIOX
Circassia Pharmaceuticals
71.40
11.29
18.78%
GB:AGY
Allergy Therapeutics
9.90
4.70
90.38%
GB:AVCT
Avacta Group plc
81.40
34.40
73.19%
GB:PRTC
PureTech Health
126.00
-41.40
-24.73%
GB:OXB
Oxford BioMedica
630.00
204.50
48.06%

Circassia Pharmaceuticals Corporate Events

Delistings and Listing ChangesRegulatory Filings and Compliance
NIOX Group Updates Total Voting Rights Following Share Option Exercises
Neutral
Oct 31, 2025

NIOX Group plc announced an update on its total voting rights, revealing that the company’s issued share capital consists of 417,879,117 Ordinary Shares, each with one voting right. This follows the exercise of options by employees over 7,500 Ordinary Shares under the company’s share option schemes. The new shares have been admitted via block listing and rank equally with existing shares. This update is crucial for shareholders as it affects their calculations for notifying interest changes under FCA rules.

The most recent analyst rating on (GB:NIOX) stock is a Hold with a £76.00 price target. To see the full list of analyst forecasts on Circassia Pharmaceuticals stock, see the GB:NIOX Stock Forecast page.

Regulatory Filings and Compliance
NIOX Group Announces Total Voting Rights and Share Option Exercise
Neutral
Oct 1, 2025

NIOX Group plc, a company listed on the AIM market, has announced its total voting rights as of September 30, 2025. The company’s issued share capital consists of 417,871,617 ordinary shares, each carrying one voting right, with no shares held in treasury. Recently, employees exercised options over 45,432 ordinary shares under the company’s share option schemes. The admission of these new shares has been satisfied via block listing and will rank equally with existing shares. This information is crucial for shareholders to determine their notification requirements under the FCA’s Disclosure and Transparency Rules.

The most recent analyst rating on (GB:NIOX) stock is a Hold with a £76.00 price target. To see the full list of analyst forecasts on Circassia Pharmaceuticals stock, see the GB:NIOX Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
NIOX Group Reports Strong H1 2025 Financial Results Amid Global Expansion
Positive
Sep 30, 2025

NIOX Group PLC reported a strong financial performance for the first half of 2025, with a 20% increase in revenue to £25.2 million and a 30% rise in adjusted EBITDA to £9.2 million. This growth was driven by increased adoption of FeNO testing globally, supported by new guidelines and market expansion, as well as a significant rise in research sales due to unexpected clinical trial activity. The company remains debt-free and well-positioned for sustained growth, focusing on expanding its presence in the US market through a revised sales strategy.

The most recent analyst rating on (GB:NIOX) stock is a Hold with a £76.00 price target. To see the full list of analyst forecasts on Circassia Pharmaceuticals stock, see the GB:NIOX Stock Forecast page.

Regulatory Filings and Compliance
NIOX Group Updates Total Voting Rights After Share Option Exercise
Neutral
Sep 1, 2025

NIOX Group plc, a company listed on the AIM market, has announced an update on its total voting rights following the exercise of share options by employees. The company’s issued share capital now stands at 417,826,185 Ordinary Shares, with no shares held in treasury. This update is significant for shareholders as it affects the calculations needed to determine their interest in the company under the FCA’s Disclosure and Transparency Rules.

The most recent analyst rating on (GB:NIOX) stock is a Hold with a £76.00 price target. To see the full list of analyst forecasts on Circassia Pharmaceuticals stock, see the GB:NIOX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 20, 2025