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Genflow Biosciences Plc (GB:GENF)
LSE:GENF

Genflow Biosciences Plc (GENF) AI Stock Analysis

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GB:GENF

Genflow Biosciences Plc

(LSE:GENF)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
2.00p
▼(-11.11% Downside)
The score is primarily constrained by weak financial performance (no revenue, ongoing losses, continued cash burn) and a weakened balance sheet with negative equity. Technicals are moderately supportive given the price trend above key moving averages, but valuation remains pressured due to losses and no dividend support.

Genflow Biosciences Plc (GENF) vs. iShares MSCI United Kingdom ETF (EWC)

Genflow Biosciences Plc Business Overview & Revenue Model

Company DescriptionGenflow Biosciences plc operates as a biotechnology company that focuses on developing biological interventions aimed at tackling the effects of ageing, slowing or halting the ageing process, and reducing the incidence of age-related diseases with increase in health span. Its lead compound is GF-1002, a suspension of an adeno-associated viral vector-based gene therapy for intravenous infusion. The company is also developing GF-3001, a topical delivery of SIRT6 to the skin; and GF-4001, a non-human pipeline anti-aging for veterinary use. The company was incorporated in 2021 and is headquartered in London, the United Kingdom.
How the Company Makes Money

Genflow Biosciences Plc Financial Statement Overview

Summary
Income Statement
Balance Sheet
Cash Flow
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue-150.95K0.000.000.000.000.00
Gross Profit-150.95K-1.20K-1.03K-130.000.000.00
EBITDA-1.27M-1.59M-1.80M-1.33M-988.10K-1.09K
Net Income-1.27M-1.59M-1.63M-1.34M-988.29K-651.01K
Balance Sheet
Total Assets468.38K385.91K1.07M2.62M276.55K283.78K
Cash, Cash Equivalents and Short-Term Investments279.44K278.68K683.97K2.36M224.00K254.23K
Total Debt0.000.000.000.000.000.00
Total Liabilities771.38K788.92K345.74K250.99K221.43K64.80K
Stockholders Equity-303.00K-403.01K725.91K2.37M55.12K218.98K
Cash Flow
Free Cash Flow-1.28M-1.08M-1.66M-1.37M-747.38K-439.46K
Operating Cash Flow-1.28M-1.08M-1.66M-1.37M-747.38K-439.46K
Investing Cash Flow372.000.00-2.44K-2.48K198.50K216.55K
Financing Cash Flow865.22K656.63K0.003.50M783.71K1.96M

Genflow Biosciences Plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
£9.38M-3.80-648.46%
47
Neutral
£28.99M-5.93-202.14%23.76%
45
Neutral
£4.30M-1.58-53.79%85.56%
45
Neutral
£864.14K-1.58-85.21%44.32%60.00%
43
Neutral
£6.14M-5.54-433.59%
41
Neutral
£3.08M-0.28418.49%27.86%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:GENF
Genflow Biosciences Plc
1.90
-0.02
-1.04%
GB:TCF
Evgen Pharma
0.21
-0.55
-72.67%
GB:CIZ
Cizzle Biotechnology Holdings PLC
1.55
-0.35
-18.42%
GB:PYC
Physiomics
0.29
-0.54
-65.45%
GB:SAR
Sareum Holdings
20.00
-2.50
-11.11%
GB:VAL
ValiRx plc
0.41
-0.27
-39.26%

Genflow Biosciences Plc Corporate Events

Business Operations and StrategyProduct-Related Announcements
Genflow Biosciences Completes Safe Dosing Phase in Canine Gene Therapy Trial
Positive
Dec 16, 2025

Genflow Biosciences Plc announced the successful completion of the dosing phase in their canine gene therapy trial, with no adverse events reported, indicating a strong safety profile. The trial, which began in March 2025, aims to assess the efficacy of their SIRT6-based gene therapy in extending healthspan, with initial results expected in January 2026 and further assessments in mid-2026. The company plans to explore early-stage licensing opportunities with animal health companies based on the efficacy data.

Business Operations and Strategy
Genflow Biosciences to Attend J.P. Morgan Healthcare Conference
Positive
Dec 11, 2025

Genflow Biosciences Plc announced its participation in the 44th Annual J.P. Morgan Healthcare Conference, a major global investment event in the healthcare sector. This participation is seen as a strategic move to engage with potential partners and investors as Genflow advances its gene-therapy pipeline, particularly focusing on lipid nanoparticle delivery for mRNA SIRT6 therapeutics, which could open new opportunities in the longevity space.

Regulatory Filings and Compliance
Genflow Biosciences Announces Total Voting Rights Update
Neutral
Oct 31, 2025

Genflow Biosciences Plc announced that as of 31 October 2025, the company’s total issued share capital consists of 493,547,942 Ordinary Shares, all with voting rights. This information is crucial for shareholders to determine their notification requirements under the Financial Conduct Authority’s rules, potentially impacting investment decisions and stakeholder engagement.

Business Operations and Strategy
Genflow Biosciences Strengthens IP Portfolio with New European Patent Publication
Positive
Oct 22, 2025

Genflow Biosciences Plc announced the publication of its second European patent application for a SIRT6 gene variant targeting non-alcoholic steatohepatitis (NASH), marking a significant milestone in its intellectual property portfolio. This development strengthens Genflow’s IP leadership in the longevity and metabolic disease space, establishing a robust European patent framework that supports its therapeutic platform and future clinical programs, thereby enhancing partnership potential and long-term value creation.

Business Operations and Strategy
Genflow Biosciences Secures Key Patent Milestone for Longevity Gene Therapy
Positive
Oct 20, 2025

Genflow Biosciences Plc announced that the European Patent Office has recognized the patentability of its SIRT6 variant patent, marking a significant milestone in its intellectual property strategy. This development provides provisional protection across participating EPO member states, positioning Genflow to benefit from EU grant opportunities and strengthening its leverage in partnerships with pharmaceutical and biotech companies. The formal recognition of this patent underscores Genflow’s progress in securing its intellectual property and enhances its strategic position for future collaborations and funding.

Business Operations and StrategyProduct-Related Announcements
Genflow Biosciences Advances Dog Aging Study with Successful Gene Therapy Administration
Positive
Oct 10, 2025

Genflow Biosciences Plc has successfully administered its proprietary SIRT6-centenarian gene therapy for the second time in a clinical trial involving elderly dogs, demonstrating excellent safety and tolerability. This milestone highlights the potential of Genflow’s gene therapy platform to extend beyond human health into the lucrative global animal health market, with plans to advance its animal health initiative further. The company is committed to leveraging its innovative gene therapy platform to create value for shareholders and establish partnerships in the field of genetic longevity therapeutics.

Delistings and Listing ChangesPrivate Placements and Financing
Genflow Biosciences Raises £440,000 Through Alternative Share Issuance
Positive
Oct 9, 2025

Genflow Biosciences Plc has decided to terminate a previously announced subscription and instead raised £440,000 through an alternative transaction involving the issuance of 40 million new ordinary shares to CEO Eric Leire. This decision was made as the alternative is more favorable and less dilutive for shareholders. The new shares will be admitted to trading on the London Stock Exchange, with a total of 493,547,942 shares in issue post-admission. This move reflects confidence in Genflow’s mission to advance its gene therapy programs, with the additional capital supporting near-term objectives.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 04, 2026