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Grifols, SA (ES:GRF)
BME:GRF

Grifols (GRF) AI Stock Analysis

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ES:GRF

Grifols

(BME:GRF)

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Neutral 53 (OpenAI - 5.2)
Rating:53Neutral
Price Target:
€9.00
▲(2.74% Upside)
Action:ReiteratedDate:03/06/26
The score is primarily constrained by balance-sheet risk (high leverage and limited debt coverage) despite improving revenue, margins, and cash generation. Weak technical signals (below major moving averages with negative MACD) further weigh on the outlook, while a reasonable P/E and modest dividend provide only partial support.
Positive Factors
Integrated plasma-to-product model
Vertical integration from plasma collection through fractionation and distribution creates a durable competitive advantage: secures raw supply, captures value across the chain, and supports recurring revenues for immunoglobulins and albumin, reducing supply risk and improving long-term margin control.
Improved cash generation and positive FCF
Material positive free cash flow and improved operating cash flow underpin financial resilience: allows funding of capex, working capital and gradual deleveraging without relying solely on external financing, supporting sustainable operations and strategic investments over the medium term.
Steady revenue growth and margin recovery
Consistent mid-to-high single-digit top-line growth combined with a rebound in EBIT and net margins reflects durable demand for plasma-derived therapies and diagnostics recurring consumables, indicating improved operating leverage and stronger earnings quality versus the 2022–2023 trough.
Negative Factors
High absolute leverage
A very large debt stock and elevated debt-to-equity materially constrain financial flexibility: increases interest expense sensitivity, limits strategic optionality (M&A, buybacks), and raises default/refinancing risk in adverse conditions, leaving less room for cyclical stress.
Limited debt coverage and slow deleveraging
Operating cash flow covers only a small fraction of total debt and FCF growth weakened, implying deleveraging will be gradual. This raises refinancing risk and limits rapid capital-structure repair, constraining investment flexibility and increasing sensitivity to cash-flow shocks.
Margins still below pre-cycle peak; earnings volatile
Though margins recovered, they remain materially below prior peaks and earnings have been volatile. This reduces predictability of profits, leaving a smaller buffer against pricing, regulatory, or supply disruptions and complicates long-term planning and return consistency.

Grifols (GRF) vs. iShares MSCI Spain ETF (EWP)

Grifols Business Overview & Revenue Model

Company DescriptionGrifols, S.A. engages in the procurement, manufacture, preparation, and sale of therapeutic products, primarily hemoderivatives. The company operates through Bioscience, Hospital, Diagnostic, Bio Supplies, and Others divisions. The Bioscience division researches, develops, produces, and markets plasma-derived medicines and other innovative solutions to treat patients with chronic, rare, prevalent, and life-threatening diseases. It offers immunoglobulins, alpha-1 antitrypsin, albumin, clotting factors, and hyperimmune globulins. The Hospital division offers non-biological pharmaceutical products and medical supplies clinical nutrition, intravenous therapy, and medical devices. The Diagnostic division researches, develops, produces, and commercializes diagnostic products that span the healthcare continuum from prevention, screening, diagnosis, and prognosis to disease and treatment monitoring to serve professionals. The Bio Supplies division provides biological materials for life-science research, clinical trials, and for manufacturing pharmaceutical and diagnostic products. Its products and services are used by healthcare providers to diagnose and treat patients with hemophilia, immune deficiencies, infectious diseases, and other medical conditions. The company serves public and private customers; and wholesalers, distributors, group purchasing organizations, blood banks, hospitals and care institutions, and national health systems. Grifols, S.A. has a technology collaboration agreement with Mondragon. The company was founded in 1940 and is headquartered in Barcelona, Spain.
How the Company Makes MoneyGrifols primarily makes money by collecting human plasma through its network of plasma donation centers and converting that plasma into plasma-derived medicines that are sold to hospitals, pharmacies, and healthcare systems. A key revenue stream comes from the sale of immunoglobulins and other plasma proteins (e.g., albumin and other therapies), where Grifols captures value across the chain: plasma sourcing/collection, fractionation/manufacturing, and commercial distribution. In addition, Grifols generates revenue from its Diagnostic business by selling analyzers/instruments along with recurring consumables (reagents, test kits, and related supplies) used for blood screening and clinical testing; this model typically includes ongoing reagent/consumable demand tied to installed instrument bases. The company’s earnings are influenced by factors such as plasma supply availability, manufacturing yields and capacity utilization, regulatory approvals and pricing/reimbursement conditions in end markets, and long-term supply agreements with healthcare providers and distributors. Specific partnership details not publicly specified here: null.

Grifols Financial Statement Overview

Summary
Operational recovery is evident with steady revenue growth and improved profitability and cash flow versus the 2022–2023 trough. However, the balance sheet is a major constraint: leverage is elevated (debt-heavy structure), equity has declined, and cash flow coverage of total debt remains limited, increasing financial risk and reducing flexibility.
Income Statement
63
Positive
Revenue has expanded steadily from 2022–2025 (mid-to-high single-digit growth recently), showing resilient demand. Profitability has improved meaningfully versus 2023, with EBIT margin rebounding to ~16.6% in 2025 and net margin recovering to ~5.3% (from ~0.9% in 2023). However, margins remain well below the 2020 peak (net margin ~11.6%), and earnings have shown notable volatility over the period, which reduces confidence in consistency.
Balance Sheet
44
Neutral
Leverage is elevated: total debt remains very high (~€9.6B in 2025) and debt-to-equity is ~1.83x, indicating meaningful balance-sheet risk and reduced flexibility. Equity has declined versus 2022–2024, and returns on equity are modest (~7.6% in 2025) after very weak levels in 2023–2024. The main positive is that the company has maintained a sizable equity base relative to assets, but overall the capital structure is still debt-heavy.
Cash Flow
58
Neutral
Cash generation has improved versus the 2022–2023 period: operating cash flow rose to ~€1.05B in 2025 and free cash flow is solidly positive (~€0.78B). Free cash flow covers a meaningful portion of earnings (about 0.75x in 2025), supporting earnings quality. Offsetting this, free cash flow growth turned negative in 2025, and operating cash flow remains low relative to total debt (coverage ~0.52x), highlighting that deleveraging capacity may be gradual.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue7.52B7.21B6.59B6.06B4.93B
Gross Profit2.86B2.85B2.49B2.23B1.96B
EBITDA1.25B1.61B1.18B1.21B944.03M
Net Income401.89M156.92M59.31M208.28M265.33M
Balance Sheet
Total Assets19.71B21.41B21.44B21.53B19.23B
Cash, Cash Equivalents and Short-Term Investments825.49M1.00B645.72M591.24M2.68B
Total Debt8.74B10.09B10.12B9.75B9.32B
Total Liabilities12.11B12.80B13.47B13.08B11.09B
Stockholders Equity5.27B5.88B5.83B6.13B6.10B
Cash Flow
Free Cash Flow782.00M669.63M-87.14M-386.43M281.89M
Operating Cash Flow1.05B902.17M208.28M-10.87M596.98M
Investing Cash Flow-579.00M886.67M-397.64M-1.98B-29.39M
Financing Cash Flow-529.00M-1.36B186.04M-173.49M1.47B

Grifols Technical Analysis

Technical Analysis Sentiment
Negative
Last Price8.76
Price Trends
50DMA
10.56
Negative
100DMA
10.67
Negative
200DMA
11.22
Negative
Market Momentum
MACD
-0.51
Positive
RSI
22.91
Positive
STOCH
3.00
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ES:GRF, the sentiment is Negative. The current price of 8.76 is below the 20-day moving average (MA) of 9.94, below the 50-day MA of 10.56, and below the 200-day MA of 11.22, indicating a bearish trend. The MACD of -0.51 indicates Positive momentum. The RSI at 22.91 is Positive, neither overbought nor oversold. The STOCH value of 3.00 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ES:GRF.

Grifols Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
€3.94B23.1323.03%1.50%-9.39%-25.92%
71
Outperform
€1.55B17.1935.36%1.04%7.35%5375.64%
59
Neutral
€2.44B35.123.96%1.22%13.32%
53
Neutral
€5.42B18.757.56%1.37%7.31%158.58%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
€1.39B20.1718.13%3.51%11.04%8.29%
46
Neutral
€202.54M41.662.03%1.91%-1.19%-54.66%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ES:GRF
Grifols
8.81
-0.29
-3.20%
ES:ALM
Almirall
11.38
1.40
14.05%
ES:FAE
Faes Farma
4.47
1.05
30.85%
ES:RJF
LABORATORIO REIG JOFRE
2.48
-0.13
-4.80%
ES:ROVI
Laboratorios Farmaceuticos Rovi
78.00
26.12
50.34%
ES:PHM
Pharma Mar SA
87.55
-1.32
-1.48%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 06, 2026