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Editas Medicine Inc (EDIT)
NASDAQ:EDIT
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Editas Medicine (EDIT) AI Stock Analysis

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EDIT

Editas Medicine

(NASDAQ:EDIT)

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Neutral 55 (OpenAI - 4o)
Rating:55Neutral
Price Target:
$4.00
▲(9.59% Upside)
Editas Medicine's overall stock score is primarily influenced by its financial performance challenges, including lack of revenue growth and persistent losses. Despite strong cash reserves, the company faces high risks due to negative cash flow and reliance on external funding. Technical analysis provides a more positive outlook with bullish momentum, but valuation remains a concern due to ongoing losses and lack of dividends.
Positive Factors
Innovative Product Development
The nomination of EDIT-401 as the lead candidate highlights Editas's commitment to advancing its CRISPR technology. This strategic move positions the company to potentially lead in the gene-editing space, offering a novel therapeutic approach that could significantly impact patient outcomes.
Strong Cash Reserves
Editas Medicine's substantial cash reserves provide a financial cushion, enabling continued investment in R&D and strategic initiatives. This financial strength supports long-term sustainability and the ability to weather periods of negative cash flow typical in biotech R&D phases.
Partnerships and Collaborations
Collaborations with industry leaders enhance Editas's research capabilities and provide funding opportunities. These partnerships are crucial for advancing clinical trials and potentially accelerating the commercialization of its therapies, strengthening its market position.
Negative Factors
Negative Cash Flow
Persistent negative cash flow indicates operational struggles and high cash burn. This reliance on external funding poses a risk to Editas's long-term financial stability, potentially limiting its ability to independently sustain R&D activities and commercial operations.
Revenue Decline
The sharp decline in revenue underscores challenges in achieving a commercially viable model. This lack of revenue growth highlights the difficulty in transitioning from R&D to a revenue-generating stage, impacting the company's financial health and investor confidence.
Leadership Changes
Leadership changes, such as the departure of key executives, can disrupt strategic continuity and operational efficiency. This may affect Editas's ability to execute its long-term vision and maintain momentum in its R&D and commercialization efforts.

Editas Medicine (EDIT) vs. SPDR S&P 500 ETF (SPY)

Editas Medicine Business Overview & Revenue Model

Company DescriptionEditas Medicine, Inc., a clinical stage genome editing company, focuses on developing transformative genomic medicines to treat a range of serious diseases. It develops a proprietary gene editing platform based on CRISPR technology. The company develops EDIT-101, which is in Phase 1/2 clinical trial for Leber Congenital Amaurosis 10 that leads to inherited childhood blindness. It also develops EDIT-102 for the treatment of Usher Syndrome 2A, which is a form of retinitis pigmentosa that also includes hearing loss; autosomal dominant retinitis pigmentosa, a progressive form of retinal degeneration; and EDIT-301 to treat sickle cell disease and transfusion-dependent beta-thalassemia. In addition, the company is developing gene-edited Natural Killer cell medicines to treat solid tumor cancers; alpha-beta T cells for multiple cancers; and gamma delta T cell therapies to treat cancer, as well as has an early discovery program to develop a therapy to treat a neurological disease. It has a research collaboration with Juno Therapeutics, Inc. to develop engineered T cells for cancer; strategic alliance and option agreement with Allergan Pharmaceuticals International Limited to discover, develop, and commercialize new gene editing medicines for a range of ocular disorders; and research collaboration with Asklepios BioPharmaceutical, Inc. to develop a therapy to treat a neurological disease, as well as research collaboration with AskBio. The company was formerly known as Gengine, Inc. and changed its name to Editas Medicine, Inc. in November 2013. Editas Medicine, Inc. was incorporated in 2013 and is based in Cambridge, Massachusetts.
How the Company Makes MoneyEditas Medicine generates revenue through a combination of product development agreements, collaborations, and potential future sales of therapies that successfully pass through clinical trials. The company has established partnerships with various pharmaceutical companies and research institutions, which often provide funding in exchange for rights to co-develop or commercialize specific therapies. Additionally, Editas may receive milestone payments and royalties based on the commercial success of its products. The company's financial performance is also influenced by grants and investments aimed at supporting its research and development initiatives.

Editas Medicine Key Performance Indicators (KPIs)

Any
Any
Operating Expense Breakdown
Operating Expense Breakdown
Details core costs like R&D, marketing, and admin, offering insight into how efficiently the company runs and where it’s prioritizing investment, crucial for understanding Editas Medicine's focus on innovation and operational strategy.
Chart InsightsEditas Medicine's R&D expenses have shown volatility, with a significant drop in early 2025, possibly reflecting strategic cost management or project completion. General and Administrative expenses have gradually decreased since late 2023, indicating a focus on operational efficiency. These trends suggest a strategic shift towards optimizing resources, which could enhance financial stability and support future innovation efforts.
Data provided by:Main Street Data

Editas Medicine Earnings Call Summary

Earnings Call Date:Aug 12, 2025
(Q2-2024)
|
% Change Since: |
Next Earnings Date:Nov 10, 2025
Earnings Call Sentiment Positive
The call highlighted significant progress in both clinical trials and in vivo pipeline development. Financial stability was assured despite a higher burn rate. However, challenges such as increased expenses and regulatory issues around fertility support present hurdles. Overall, the company's advancements in gene editing and robust clinical trial outcomes provide a positive outlook.
Q2-2024 Updates
Positive Updates
Reni-cel Clinical Trials Progress
Completed adolescent cohort enrollment for the RUBY trial, and adult cohort enrollment in the EdiTHAL trial. Clinical data from RUBY and EdiTHAL trials show promising results with all patients free from vaso-occlusive events and a high level of fetal hemoglobin.
In Vivo Pipeline Advancements
On track to establish in vivo preclinical proof of concept for an undisclosed indication by the end of the year. Strengthening in vivo discovery capabilities and pursuing a differentiated strategy for gene editing.
Financial Position
Cash, cash equivalents, and marketable securities as of June 30 were $318 million, expected to fund operations into 2026.
Manufacturing Improvements
Robust manufacturing process for reni-cel with a low failure rate, potentially reducing patient burden and cost.
Negative Updates
Increased Burn Rate
Higher burn rate this quarter due to increased external R&D expenses, primarily related to clinical and manufacturing costs.
Regulatory and Market Challenges
Concerns regarding HHS decision on fertility preservation coverage for sickle cell therapies, which may affect market dynamics.
Company Guidance
During the Editas Medicine Q2 2024 earnings call, CEO Gilmore O'Neill outlined the company's strategic progress, emphasizing three main pillars: advancing reni-cel towards BLA and commercialization, building a differentiated in vivo editing pipeline, and enhancing business development with a focus on intellectual property. The RUBY trial data for sickle cell disease showed promising results, with 18 patients having follow-up periods ranging from 2.4 to 22.8 months and demonstrating robust anemia correction. The EdiTHAL trial for beta-thalassemia included data from 7 patients with 4.1 to 12.8 months follow-up. Financially, Editas reported cash, cash equivalents, and marketable securities totaling $318 million as of June 30, 2024, with a burn rate increase due to R&D expenses. They expect to fund operations into 2026. The company is also on track to establish in vivo preclinical proof of concept by year-end, with a focus on leveraging indel technology for gene upregulation, targeting rare and orphan diseases initially.

Editas Medicine Financial Statement Overview

Summary
Editas Medicine faces significant financial challenges typical of biotech firms in the R&D phase. The lack of revenue growth and persistent losses indicate difficulties in transitioning to a commercially viable model. The balance sheet is bolstered by strong cash reserves, yet the continuous negative cash flow suggests an ongoing reliance on external funding. Investors should be cautious of the high risks associated with the company's current financial position.
Income Statement
20
Very Negative
Editas Medicine has shown a volatile revenue trajectory with a significant drop to zero revenue in 2024 from previous levels. The company has consistently reported negative net income, leading to negative profit margins. This indicates challenges in achieving profitability, common in the biotech industry, which often requires substantial R&D investments without immediate revenue.
Balance Sheet
40
Negative
The company's balance sheet exhibits moderate financial health with a significant cash reserve relative to its total assets. The debt-to-equity ratio is low, suggesting conservative use of debt. However, the continuous decline in stockholders' equity indicates erosion of shareholder value, which is a concern.
Cash Flow
30
Negative
Editas Medicine has consistently faced negative operating and free cash flows, reflecting operational struggles and high cash burn. Although there are instances of positive financing cash flows, this is likely due to capital raises rather than operational efficiency, posing a risk to long-term sustainability.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue38.90M32.31M78.12M19.71M25.54M90.73M
Gross Profit35.92M26.50M72.06M13.38M20.49M-67.26M
EBITDA-225.89M-233.11M-163.12M-219.61M-188.09M-130.88M
Net Income-236.86M-237.09M-153.22M-220.43M-192.50M-115.98M
Balance Sheet
Total Assets210.58M341.59M499.15M514.32M677.48M572.60M
Cash, Cash Equivalents and Short-Term Investments178.50M269.91M323.11M344.27M499.85M402.11M
Total Debt77.81M35.03M36.54M43.95M26.38M26.14M
Total Liabilities191.39M207.31M150.06M153.64M123.84M179.02M
Stockholders Equity19.19M134.27M349.10M360.68M553.64M393.59M
Cash Flow
Free Cash Flow-204.94M-219.11M-136.90M-181.47M-171.78M-187.00M
Operating Cash Flow-201.36M-210.28M-132.18M-177.35M-163.80M-179.84M
Investing Cash Flow213.97M162.15M-3.73M114.07M-54.47M-140.52M
Financing Cash Flow61.49M56.03M118.04M1.28M282.11M224.12M

Editas Medicine Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price3.65
Price Trends
50DMA
3.18
Positive
100DMA
2.83
Positive
200DMA
2.15
Positive
Market Momentum
MACD
0.18
Positive
RSI
51.54
Neutral
STOCH
37.62
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For EDIT, the sentiment is Neutral. The current price of 3.65 is below the 20-day moving average (MA) of 3.77, above the 50-day MA of 3.18, and above the 200-day MA of 2.15, indicating a neutral trend. The MACD of 0.18 indicates Positive momentum. The RSI at 51.54 is Neutral, neither overbought nor oversold. The STOCH value of 37.62 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for EDIT.

Editas Medicine Risk Analysis

Editas Medicine disclosed 71 risk factors in its most recent earnings report. Editas Medicine reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Editas Medicine Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$259.88M-48.36%334.02%
55
Neutral
$321.01M-188.58%-41.97%-20.86%
54
Neutral
$262.61M-68.93%-72.45%-28.60%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
41
Neutral
$228.38M-31.30%36.26%
33
Underperform
$181.29M-686.12%
30
Underperform
$152.76M-9999.00%-4.60%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
EDIT
Editas Medicine
3.65
0.47
14.78%
CLLS
Cellectis SA
3.47
1.61
86.56%
FHTX
Foghorn Therapeutics
3.90
-3.82
-49.48%
ELTX
Elicio Therapeutics
9.50
4.85
104.30%
VOR
Vor Biopharma
27.76
13.22
90.92%
CRBU
Caribou Biosciences
2.50
0.73
41.24%

Editas Medicine Corporate Events

Product-Related Announcements
Editas Medicine Unveils Promising Preclinical Data on EDIT-401
Positive
Oct 9, 2025

On October 9, 2025, Editas Medicine presented in vivo preclinical proof-of-concept data for their experimental therapy, EDIT-401, at the European Society of Gene and Cell Therapy Congress. The therapy aims to significantly reduce LDL-cholesterol by upregulating the LDL receptor, showing promising results in non-human primates and mice with reductions exceeding 90% within 48 hours of a single dose, potentially impacting the company’s position in the gene therapy market.

The most recent analyst rating on (EDIT) stock is a Buy with a $5.00 price target. To see the full list of analyst forecasts on Editas Medicine stock, see the EDIT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Editas Medicine Advances EDIT-401 for LDL Reduction
Positive
Sep 2, 2025

On September 2, 2025, Editas Medicine announced the nomination of EDIT-401 as its lead in vivo development candidate. EDIT-401 is designed to reduce LDL cholesterol levels by editing the LDLR gene, showing promising preclinical results with a significant reduction in LDL-C levels and increased LDLR protein expression. The company plans to focus on advancing EDIT-401 to human proof-of-concept and aims to submit an IND or CTA by mid-2026. Additionally, Editas confirmed its financial stability, projecting its cash runway to extend into the second quarter of 2027.

The most recent analyst rating on (EDIT) stock is a Buy with a $4.00 price target. To see the full list of analyst forecasts on Editas Medicine stock, see the EDIT Stock Forecast page.

Editas Medicine Inc. Faces Significant Business Risks: Key Factors for Investors to Watch
Aug 14, 2025

Editas Medicine Inc. faces significant business risks as outlined in their Quarterly Report on Form 10-Q. The report highlights potential challenges, including those mentioned in the ‘Summary of Risk Factors’ and Part I, ‘Item 1’. These risks could impact the company’s operational and financial performance, necessitating careful consideration by stakeholders. Investors and analysts should closely monitor these factors to assess their potential impact on the company’s future prospects.

Editas Medicine Reports Q2 2025 Progress and Financials
Aug 14, 2025

Editas Medicine, Inc. is a pioneering gene editing company focused on developing transformative medicines for serious diseases using CRISPR technology. In its second quarter 2025 earnings report, Editas Medicine highlighted significant progress in its strategic initiatives, including the selection of a lead development candidate and advancements in its collaboration with Bristol Myers Squibb.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 23, 2025