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Corvus Pharmaceuticals Inc (CRVS)
NASDAQ:CRVS

Corvus Pharmaceuticals (CRVS) AI Stock Analysis

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CRVS

Corvus Pharmaceuticals

(NASDAQ:CRVS)

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Neutral 50 (OpenAI - 5.2)
Rating:50Neutral
Price Target:
$7.50
▲(8.38% Upside)
The score is held back primarily by weak financial performance (pre-revenue with ongoing losses and material cash burn). The latest earnings call provides support via improved quarterly loss trends, a cash runway into Q4 2026, and meaningful clinical trial progress, but near-term technical momentum is soft and valuation is constrained by negative earnings.
Positive Factors
Clinical Advancements
The 39% objective response rate in Phase 1 trials for T-cell lymphoma shows strong potential for socalitinib, enhancing Corvus's drug pipeline and market prospects.
Cash Position
A strong cash position provides operational runway until Q1 2026, supporting ongoing R&D and strategic initiatives without immediate financial strain.
Strategic Leadership
The appointment of a new director enhances governance and oversight, potentially improving operational effectiveness and stakeholder confidence.
Negative Factors
Increasing Net Loss
Rising net losses indicate financial strain and highlight the need for successful commercialization of drug candidates to achieve profitability.
R&D Expenses
Higher R&D expenses reflect increased investment in drug development but also contribute to financial losses, stressing the importance of successful trial outcomes.
Cash Flow Challenges
Negative cash flows indicate reliance on external financing, posing risks to sustainability if clinical advancements do not lead to revenue generation.

Corvus Pharmaceuticals (CRVS) vs. SPDR S&P 500 ETF (SPY)

Corvus Pharmaceuticals Business Overview & Revenue Model

Company DescriptionCorvus Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of immuno-oncology therapies. Its lead product candidate is Mupadolimab (CPI-006), an anti-CD73 monoclonal antibody, which is in Phase Ib/II clinical trial for non-small cell lung cancer and head and neck cancers. The company also develops CPI-818, a covalent inhibitor of ITK, which is in Phase I/Ib clinical trial to treat patients with various malignant T-cell lymphomas, as well as designed to inhibit the proliferation of certain malignant T-cells; and Ciforadenant (CPI-444), an oral, small molecule antagonist of the A2A receptor that is in Phase II clinical trial for patients with either advanced or refractory renal cell cancer. Its preclinical stage products include CPI-182, an antibody designed to block inflammation and myeloid suppression; and CPI-935, an adenosine A2B receptor antagonist to prevent fibrosis. Corvus Pharmaceuticals, Inc. has a strategic collaboration with Angel Pharmaceuticals for the development its pipeline of targeted investigational medicines. The company was incorporated in 2014 and is based in Burlingame, California.
How the Company Makes MoneyCorvus Pharmaceuticals generates revenue primarily through the development and potential commercialization of its immuno-oncology drug candidates. The company typically seeks to advance its drug candidates through clinical trials and may enter into licensing agreements or partnerships with larger pharmaceutical companies to co-develop or market these treatments. Additionally, Corvus may receive milestone payments and royalties from its partners based on the success and sales of the developed drugs. Grants and research funding from governmental or non-profit organizations can also contribute to its revenue streams.

Corvus Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 05, 2026
Earnings Call Sentiment Positive
The earnings call presented significant positive developments, including a notable reduction in net loss, a strong cash position, and successful clinical trial progress for soquelitinib. However, increased R&D expenses and delays in trial result reporting were challenges. Overall, the positive aspects, particularly related to clinical advancements and financial improvements, seem to outweigh the negatives.
Q3-2025 Updates
Positive Updates
Significant Reduction in Net Loss
The net loss for Q3 2025 was $10.2 million, a substantial decrease from the $40.2 million loss in Q3 2024.
Strong Cash Position
Corvus had cash, cash equivalents, and marketable securities totaling $65.7 million as of September 30, 2025, up from $52 million at the end of 2024.
Successful Enrollment in Phase I Trial for Soquelitinib
Enrollment in the extension Cohort 4 of the Phase I trial for soquelitinib was completed, with results expected in January 2026.
Upcoming Phase II Trial for Atopic Dermatitis
The initiation of the Phase II atopic dermatitis trial for soquelitinib is on track for early Q1 2026, involving approximately 200 patients globally.
Positive Efficacy Data for Soquelitinib
Cohort 3 of the Phase I trial showed a mean percent reduction of EASI score of 64.8%, with notable patient responses.
Presentation at ASH for T Cell Lymphoma
The final results from the Phase I/Ib clinical trial of soquelitinib for relapsed/refractory T cell lymphomas will be presented at the ASH meeting in December.
Negative Updates
Increased Research and Development Expenses
R&D expenses in Q3 2025 were $8.5 million, up from $5.2 million in Q3 2024, primarily due to higher clinical trial and manufacturing costs.
Noncash Loss Related to Angel Pharmaceuticals
A noncash loss of $300,000 related to Angel Pharmaceuticals was reported in Q3 2025, compared to $700,000 in the same period in 2024.
Delayed Reporting of Phase I Trial Results
Results from the extension Cohort 4 of the Phase I trial for soquelitinib will not be reported until January 2026, delaying potential insights.
Company Guidance
During the Corvus Pharmaceuticals Third Quarter 2025 Business Update and Financial Results Conference Call, CFO Leiv Lea outlined key financial metrics, noting that research and development expenses totaled $8.5 million, a $3.3 million increase from the prior year, primarily due to costs associated with soquelitinib development. The net loss for Q3 2025 was $10.2 million, significantly reduced from a $40.2 million loss in Q3 2024. Stock compensation expenses rose to $1.2 million from $700,000. Corvus reported $65.7 million in cash and equivalents as of September 30, 2025, with current funds expected to support operations into Q4 2026. CEO Richard Miller discussed clinical progress, highlighting the completion of enrollment for extension Cohort 4 in a Phase I trial and the upcoming Phase II trial for atopic dermatitis, expected to begin in early Q1 2026.

Corvus Pharmaceuticals Financial Statement Overview

Summary
Corvus Pharmaceuticals is facing significant financial challenges with no revenue and ongoing losses. The balance sheet is stable with low leverage, but declining equity poses risks. Cash flow issues persist, driven by negative operational results and reliance on financing activities for liquidity.
Income Statement
Corvus Pharmaceuticals has consistently reported zero revenue over the years, indicating a lack of commercial success or product launches. The company also reports significant net losses, with no visible improvement in net profit margin. The EBIT and EBITDA margins are non-existent due to the absence of revenue, highlighting ongoing operational challenges.
Balance Sheet
The balance sheet shows a relatively low debt-to-equity ratio, suggesting limited leverage with a Total Debt of $1.12 million against a Stockholders' Equity of $32.57 million. Despite this, the equity ratio has declined, pointing to potential risks as liabilities increase. The company has a declining stockholders' equity over the years, indicating potential financial vulnerability.
Cash Flow
The cash flow statement reveals negative operating and free cash flows, demonstrating cash burn with no revenue inflows. Despite a recent increase in financing cash flow, the reliance on external financing is a concern. Free cash flow remains negative, reflecting continuous operational cash challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit0.000.000.000.000.00-632.00K
EBITDA-38.34M-27.46M-23.26M-32.20M-38.17M-5.36M
Net Income-15.07M-62.29M-27.03M-41.31M-43.24M-6.00M
Balance Sheet
Total Assets80.47M68.91M45.55M68.24M109.45M85.53M
Cash, Cash Equivalents and Short-Term Investments65.69M51.96M27.15M42.30M69.45M44.26M
Total Debt1.01M1.12M1.37M2.60M3.65M2.31M
Total Liabilities8.71M36.34M6.87M12.13M12.29M13.38M
Stockholders Equity71.77M32.57M38.68M56.12M97.16M72.15M
Cash Flow
Free Cash Flow-32.22M-25.42M-23.97M-27.29M-36.72M-34.85M
Operating Cash Flow-32.07M-25.42M-23.93M-27.02M-36.72M-34.78M
Investing Cash Flow-24.76M-27.48M15.54M-23.28M21.56M44.77M
Financing Cash Flow55.02M49.03M7.86M0.0062.16M1.31M

Corvus Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price6.92
Price Trends
50DMA
8.04
Negative
100DMA
7.23
Negative
200DMA
5.55
Positive
Market Momentum
MACD
-0.34
Positive
RSI
38.57
Neutral
STOCH
32.98
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CRVS, the sentiment is Negative. The current price of 6.92 is below the 20-day moving average (MA) of 7.62, below the 50-day MA of 8.04, and above the 200-day MA of 5.55, indicating a neutral trend. The MACD of -0.34 indicates Positive momentum. The RSI at 38.57 is Neutral, neither overbought nor oversold. The STOCH value of 32.98 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CRVS.

Corvus Pharmaceuticals Risk Analysis

Corvus Pharmaceuticals disclosed 73 risk factors in its most recent earnings report. Corvus Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Corvus Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$807.73M7.22220.06%79.13%2798.12%
54
Neutral
$740.96M-6.04-43.15%-2.74%
52
Neutral
$419.90M-1.73-74.88%18.39%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$425.72M-3.82-52.61%-61.54%31.25%
50
Neutral
$516.80M-12.94-35.82%79.27%
50
Neutral
$289.35M-4.22-42.25%-100.00%1.47%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CRVS
Corvus Pharmaceuticals
6.92
1.72
33.08%
ALT
Altimmune
4.08
-2.70
-39.82%
RIGL
Rigel
44.50
27.39
160.08%
NGNE
Neurogene
18.68
-0.13
-0.69%
RCKT
Rocket Pharmaceuticals
3.88
-6.85
-63.84%
ATXS
Astria Therapeutics
12.98
5.52
73.99%

Corvus Pharmaceuticals Corporate Events

Executive/Board Changes
Corvus Pharmaceuticals Appoints David Moore as Director
Neutral
Oct 2, 2025

On October 2, 2025, Corvus Pharmaceuticals appointed David Moore as a Class III director to its Board, with his term set to expire in 2028. Mr. Moore will also serve on the Compensation and Nominating Committees, receiving compensation through an annual retainer, stock options, and additional cash for his committee roles, aligning with the company’s non-employee director compensation program.

The most recent analyst rating on (CRVS) stock is a Buy with a $11.00 price target. To see the full list of analyst forecasts on Corvus Pharmaceuticals stock, see the CRVS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025