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Corvus Pharmaceuticals Inc. (CRVS)
NASDAQ:CRVS

Corvus Pharmaceuticals (CRVS) AI Stock Analysis

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CRVS

Corvus Pharmaceuticals

(NASDAQ:CRVS)

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Neutral 59 (OpenAI - 5.2)
Rating:59Neutral
Price Target:
$24.00
▲(14.61% Upside)
CRVS scores as a mid-range, higher-risk biotech: persistent pre-revenue losses and cash burn weigh most on the rating, but are partially offset by a low-debt balance sheet and improved loss trend. Technicals indicate strong momentum but with overbought readings. Recent updates (earnings call and corporate events) are supportive due to extended funding and positive soquelitinib data.
Positive Factors
Recent Capital Raise
A large underwritten equity raise materially extends funding runway and reduces near-term financing pressure. This strengthens the company's ability to advance late-stage clinical programs, cover manufacturing and trial costs, and execute strategic partnerships without immediate liquidity constraints.
Soquelitinib Phase 1 Efficacy
Robust, placebo-controlled cohort results demonstrating deep, durable EASI reductions and activity in patients refractory to standard biologics suggest meaningful clinical differentiation. This increases probability of successful Phase II outcomes and strengthens longer-term commercial and partnering prospects in atopic dermatitis.
Low Financial Leverage
Very low leverage reduces solvency and interest-rate risk, preserving strategic flexibility for R&D investment and business development. For a cash-burning clinical-stage biotech, minimal debt limits fixed financial obligations and lowers the chance of forced restructuring during development cycles.
Negative Factors
Pre-Revenue Operations and Cash Burn
Persistent pre-revenue status and sizable operating and free-cash-flow deficits mean the business cannot self-fund development. Continued cash burn elevates reliance on external capital, increases dilution risk, and places long-term viability on successful trial outcomes or partnership/licensing deals to achieve recurring revenue.
Dependence on Equity Financing
A business model reliant on equity issuance exposes shareholders to recurring dilution and ties program continuity to capital-market access. Even with a recent raise, sustained development requires ongoing funding; adverse market conditions or reduced investor appetite could constrain program timelines and strategic options.
Clinical Timeline and Execution Risk
Delays in reporting and elongated development milestones postpone de-risking events that drive partnerships or regulatory discussions. Slower readouts extend cash consumption and increase execution risk, making program valuations and commercialization timelines more uncertain over the medium term.

Corvus Pharmaceuticals (CRVS) vs. SPDR S&P 500 ETF (SPY)

Corvus Pharmaceuticals Business Overview & Revenue Model

Company DescriptionCorvus Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of immuno-oncology therapies. Its lead product candidate is Mupadolimab (CPI-006), an anti-CD73 monoclonal antibody, which is in Phase Ib/II clinical trial for non-small cell lung cancer and head and neck cancers. The company also develops CPI-818, a covalent inhibitor of ITK, which is in Phase I/Ib clinical trial to treat patients with various malignant T-cell lymphomas, as well as designed to inhibit the proliferation of certain malignant T-cells; and Ciforadenant (CPI-444), an oral, small molecule antagonist of the A2A receptor that is in Phase II clinical trial for patients with either advanced or refractory renal cell cancer. Its preclinical stage products include CPI-182, an antibody designed to block inflammation and myeloid suppression; and CPI-935, an adenosine A2B receptor antagonist to prevent fibrosis. Corvus Pharmaceuticals, Inc. has a strategic collaboration with Angel Pharmaceuticals for the development its pipeline of targeted investigational medicines. The company was incorporated in 2014 and is based in Burlingame, California.
How the Company Makes MoneyCorvus Pharmaceuticals generates revenue primarily through the development and potential commercialization of its immuno-oncology drug candidates. The company typically seeks to advance its drug candidates through clinical trials and may enter into licensing agreements or partnerships with larger pharmaceutical companies to co-develop or market these treatments. Additionally, Corvus may receive milestone payments and royalties from its partners based on the success and sales of the developed drugs. Grants and research funding from governmental or non-profit organizations can also contribute to its revenue streams.

Corvus Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 05, 2026
Earnings Call Sentiment Positive
The earnings call presented significant positive developments, including a notable reduction in net loss, a strong cash position, and successful clinical trial progress for soquelitinib. However, increased R&D expenses and delays in trial result reporting were challenges. Overall, the positive aspects, particularly related to clinical advancements and financial improvements, seem to outweigh the negatives.
Q3-2025 Updates
Positive Updates
Significant Reduction in Net Loss
The net loss for Q3 2025 was $10.2 million, a substantial decrease from the $40.2 million loss in Q3 2024.
Strong Cash Position
Corvus had cash, cash equivalents, and marketable securities totaling $65.7 million as of September 30, 2025, up from $52 million at the end of 2024.
Successful Enrollment in Phase I Trial for Soquelitinib
Enrollment in the extension Cohort 4 of the Phase I trial for soquelitinib was completed, with results expected in January 2026.
Upcoming Phase II Trial for Atopic Dermatitis
The initiation of the Phase II atopic dermatitis trial for soquelitinib is on track for early Q1 2026, involving approximately 200 patients globally.
Positive Efficacy Data for Soquelitinib
Cohort 3 of the Phase I trial showed a mean percent reduction of EASI score of 64.8%, with notable patient responses.
Presentation at ASH for T Cell Lymphoma
The final results from the Phase I/Ib clinical trial of soquelitinib for relapsed/refractory T cell lymphomas will be presented at the ASH meeting in December.
Negative Updates
Increased Research and Development Expenses
R&D expenses in Q3 2025 were $8.5 million, up from $5.2 million in Q3 2024, primarily due to higher clinical trial and manufacturing costs.
Noncash Loss Related to Angel Pharmaceuticals
A noncash loss of $300,000 related to Angel Pharmaceuticals was reported in Q3 2025, compared to $700,000 in the same period in 2024.
Delayed Reporting of Phase I Trial Results
Results from the extension Cohort 4 of the Phase I trial for soquelitinib will not be reported until January 2026, delaying potential insights.
Company Guidance
During the Corvus Pharmaceuticals Third Quarter 2025 Business Update and Financial Results Conference Call, CFO Leiv Lea outlined key financial metrics, noting that research and development expenses totaled $8.5 million, a $3.3 million increase from the prior year, primarily due to costs associated with soquelitinib development. The net loss for Q3 2025 was $10.2 million, significantly reduced from a $40.2 million loss in Q3 2024. Stock compensation expenses rose to $1.2 million from $700,000. Corvus reported $65.7 million in cash and equivalents as of September 30, 2025, with current funds expected to support operations into Q4 2026. CEO Richard Miller discussed clinical progress, highlighting the completion of enrollment for extension Cohort 4 in a Phase I trial and the upcoming Phase II trial for atopic dermatitis, expected to begin in early Q1 2026.

Corvus Pharmaceuticals Financial Statement Overview

Summary
Overall fundamentals are mixed for an early-stage biotech: no revenue and continued operating/free-cash-flow losses (TTM operating loss ~$38.9M; FCF ~$-32.2M) weigh heavily, partially offset by very low leverage (~$1.0M debt) and a materially narrower net loss versus 2024.
Income Statement
18
Very Negative
The business remains pre-revenue (reported revenue is $0 across annual periods and in TTM (Trailing-Twelve-Months)), so operating losses are the defining feature of the income statement. Profitability is weak with sizable losses in TTM (Trailing-Twelve-Months) (net loss of about $15.1M and operating loss of about $38.9M). A positive is that the net loss is materially narrower versus 2024 (about $62.3M), but overall earnings quality is still constrained by the lack of recurring revenue and ongoing R&D-driven burn typical for early-stage biotech.
Balance Sheet
64
Positive
The balance sheet is a relative strength: leverage is very low with total debt around $1.0M in TTM (Trailing-Twelve-Months) and debt-to-equity around 0.01–0.05 historically, which reduces financial risk. However, equity has declined meaningfully versus earlier years (e.g., ~$97.2M in 2021 to ~$71.8M TTM), reflecting cumulative losses, and returns on equity are negative (TTM return on equity around -0.26), highlighting ongoing value dilution risk if losses persist.
Cash Flow
27
Negative
Cash generation remains negative, with operating cash flow around -$32.1M and free cash flow around -$32.2M in TTM (Trailing-Twelve-Months), indicating continued reliance on external funding. Free cash flow growth is shown as positive in TTM, but the company is still burning cash and has not reached self-funding operations. A modest positive is that free cash flow broadly tracks net loss (free cash flow to net income ~1.0), suggesting the losses are largely reflected in cash outflows rather than being purely accounting-driven.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit0.000.000.000.000.000.00
EBITDA-38.34M-27.46M-23.26M-32.20M-38.17M-5.36M
Net Income-15.07M-62.29M-27.03M-41.31M-43.24M-6.00M
Balance Sheet
Total Assets80.47M68.91M45.55M68.24M109.45M85.53M
Cash, Cash Equivalents and Short-Term Investments65.69M51.96M27.15M42.30M69.45M44.26M
Total Debt1.01M1.12M1.37M2.60M3.65M2.31M
Total Liabilities8.71M36.34M6.87M12.13M12.29M13.38M
Stockholders Equity71.77M32.57M38.68M56.12M97.16M72.15M
Cash Flow
Free Cash Flow-32.22M-25.42M-23.97M-27.29M-36.72M-34.85M
Operating Cash Flow-32.07M-25.42M-23.93M-27.02M-36.72M-34.78M
Investing Cash Flow-24.76M-27.48M15.54M-23.28M21.56M44.77M
Financing Cash Flow55.02M49.03M7.86M0.0062.16M1.31M

Corvus Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price20.94
Price Trends
50DMA
10.53
Positive
100DMA
8.84
Positive
200DMA
6.53
Positive
Market Momentum
MACD
3.88
Negative
RSI
69.76
Neutral
STOCH
64.74
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CRVS, the sentiment is Positive. The current price of 20.94 is above the 20-day moving average (MA) of 13.92, above the 50-day MA of 10.53, and above the 200-day MA of 6.53, indicating a bullish trend. The MACD of 3.88 indicates Negative momentum. The RSI at 69.76 is Neutral, neither overbought nor oversold. The STOCH value of 64.74 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CRVS.

Corvus Pharmaceuticals Risk Analysis

Corvus Pharmaceuticals disclosed 73 risk factors in its most recent earnings report. Corvus Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Corvus Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
80
Outperform
$632.76M5.65220.06%79.13%2798.12%
59
Neutral
$1.73B-38.70-35.82%79.27%
52
Neutral
$701.30M-5.24-52.61%-61.54%31.25%
52
Neutral
$376.61M-1.55-74.88%18.39%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$273.55M-3.99-42.25%-100.00%1.47%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CRVS
Corvus Pharmaceuticals
20.70
15.34
286.19%
ALT
Altimmune
5.60
-1.04
-15.66%
RIGL
Rigel
34.86
13.21
61.02%
NGNE
Neurogene
17.66
1.81
11.42%
RCKT
Rocket Pharmaceuticals
3.48
-7.26
-67.60%

Corvus Pharmaceuticals Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Corvus Pharmaceuticals Announces Major Underwritten Public Stock Offering
Positive
Jan 23, 2026

On January 21, 2026, Corvus Pharmaceuticals entered into an underwriting agreement with Jefferies and Goldman Sachs for an underwritten public offering of 7,900,677 shares of common stock at $22.15 per share, with the underwriters purchasing at $20.821 per share and holding a 30-day option to buy an additional 1,185,101 shares. The option was fully exercised on January 22, 2026, and the offering, expected to close on January 23, 2026, is anticipated to generate approximately $188.3 million in net proceeds, which Corvus plans to use for working capital and general corporate purposes, including capital spending, research and development for its late-stage clinical trials, and sales, marketing and administrative expenses, bolstering its funding base for ongoing and future development programs.

The most recent analyst rating on (CRVS) stock is a Hold with a $27.00 price target. To see the full list of analyst forecasts on Corvus Pharmaceuticals stock, see the CRVS Stock Forecast page.

Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
Corvus Pharmaceuticals Suspends At-The-Market Equity Program
Neutral
Jan 20, 2026

On January 20, 2026, Corvus Pharmaceuticals, Inc. suspended, in connection with a proposed registered underwritten public offering, its previously established at-the-market equity program with Jefferies LLC under which up to $100 million of common stock could be sold pursuant to a prospectus supplement filed on August 6, 2024 and an effective shelf registration statement. No shares had been sold under this ATM facility prior to the suspension, leaving the entire $100 million capacity unused, and while the underlying sales agreement with Jefferies remains in force, the company will not conduct any sales under it unless and until it files a new prospectus supplement or registration statement with the SEC, signaling a shift in near-term capital-raising strategy that may affect the timing and structure of future equity issuance for investors and other stakeholders.

The most recent analyst rating on (CRVS) stock is a Hold with a $8.00 price target. To see the full list of analyst forecasts on Corvus Pharmaceuticals stock, see the CRVS Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Corvus Pharmaceuticals reports positive Phase 1 soquelitinib results
Positive
Jan 20, 2026

On January 20, 2026, Corvus Pharmaceuticals reported positive data from cohort 4 of its randomized, blinded, placebo-controlled Phase 1 trial of soquelitinib in patients with moderate to severe atopic dermatitis, showing that an extended 8-week regimen produced deeper clinical responses and a favorable safety profile consistent with earlier cohorts. In cohort 4, 75% of soquelitinib-treated patients achieved EASI 75 and 25% reached EASI 90, versus 20% and 0% on placebo, with a 72% mean EASI reduction at day 56 compared with 40% for placebo, sustained disease control into follow-up, and meaningful activity even in patients previously treated with or resistant to dupilumab and JAK inhibitors; biomarker data suggested immune-system rebalancing via ITK inhibition, and the company indicated that these results support advancing soquelitinib into a Phase 2 trial in atopic dermatitis in the first quarter of 2026, potentially strengthening its competitive positioning in oral therapies for difficult-to-treat eczema.

The most recent analyst rating on (CRVS) stock is a Hold with a $8.00 price target. To see the full list of analyst forecasts on Corvus Pharmaceuticals stock, see the CRVS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 27, 2026