Clinical TrialsAll five patients on once-daily 80 atumelnant for 10 days experienced biochemical evidence of adrenal insufficiency by Day 2 of treatment.
Drug Side EffectsAtumelnant is working and normalizing urinary free cortisol but also causing adrenal insufficiency that requires GC replacement.
Regulatory And Approval RiskRisks include clinical trial results might not meet expectations, regulatory and approval risk, funding risk, commercial adoption, the effects of COVID 19, and possible dilution.