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Cibus (CBUS)
NASDAQ:CBUS
US Market

Cibus (CBUS) AI Stock Analysis

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CBUS

Cibus

(NASDAQ:CBUS)

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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$3.00
▼(-18.48% Downside)
Action:ReiteratedDate:03/19/26
The score is held back primarily by weak financial performance (ongoing losses, cash burn, and reduced equity base), which raises financing and dilution risk. This is partly offset by constructive earnings-call takeaways on regulatory/commercial milestones and cost actions extending runway, while technicals are mixed (longer-term trend intact but near-term weakness) and valuation provides limited support due to negative earnings and no dividend.
Positive Factors
Regulatory progress across major jurisdictions
Sustained regulatory clarity across the EU, UK, US and key Latin American markets materially lowers market-access barriers for gene-edited traits. Over 2–6 months this improves the probability of licensing, accelerates partner commercialization timelines and makes multi-region rollouts more feasible and durable.
Material platform efficiency improvements
An approximately 10x improvement in editing efficiency and a shorter 12–15 month edit cycle reduces R&D time and cost per trait, increasing throughput and competitiveness. This durable technical advance strengthens bargaining power with seed partners and supports faster commercialization and recurring licensing revenue over time.
Large rice partnership and royalty opportunity
A defined pipeline of partner customers and a multi-hundred-million-dollar potential royalty pool provide a clear, scalable commercialization path. Durable partner-led royalty model leverages existing seed channels, reduces capital intensity for Cibus, and can convert technology and regulatory gains into recurring cash flows if deployment milestones are met.
Negative Factors
Consistent negative free cash flow
Sustained negative operating and free cash flow forces reliance on external funding and constrains reinvestment choices. Over the medium term, persistent cash burn increases financing frequency and dilutive risk, and limits the company's ability to scale commercial activities without secured partner funding or new capital.
Sharply eroded equity base
A dramatic fall in equity over two years weakens balance-sheet resilience, narrows borrowing capacity, and makes future equity raises more dilutive. This structural deterioration increases the cost of capital and raises execution risk for multi-year commercialization investments absent material revenue conversion.
Very small, volatile revenue base and large losses
A minimal and inconsistent revenue profile coupled with large recurring losses means the business depends on successful, timely conversion of partnerships and regulatory wins into royalties. Until revenues scale predictably, margin sustainability and self-funded growth remain uncertain, sustaining financing and execution risk.

Cibus (CBUS) vs. SPDR S&P 500 ETF (SPY)

Cibus Business Overview & Revenue Model

Company DescriptionCibus, Inc., a agricultural technology company, develops and licenses plant traits to seed companies for royalties. The company primarily focus on trait productivity in two areas, including productivity traits that enable farmers to have higher yields and reduce the use of the crop protection chemicals and fertilizers; and sustainable ingredients that enable corporations to replace ingredients that are fossil fuel based or whose production results in increased greenhouse gases. The company is based in San Diego, California.
How the Company Makes Moneynull

Cibus Earnings Call Summary

Earnings Call Date:Mar 17, 2026
(Q4-2025)
|
Next Earnings Date:May 07, 2026
Earnings Call Sentiment Positive
The call conveyed substantial positive progress on technology performance, regulatory milestones, customer engagements, and near-term commercialization plans (especially for rice and sustainable ingredients). Management also executed meaningful cost reductions and secured a $22.3M financing to extend runway. Major challenges remain: the company is still loss-making with a Q4 net loss widened ~23.6%, royalty interest expense is significant, collaboration revenue timing weighed on results, and cash runway extends only into late 2026 absent further revenue or financing. Overall, the call emphasized execution and upcoming catalysts (EU plenary vote, Interox definitive agreement, Latin America field results) that support momentum but also highlighted the need to convert progress into cash flow in the near term.
Q4-2025 Updates
Positive Updates
Strong Commercial Momentum in Rice (RISE)
Seven RISE customers represent over $200 million in potential annual royalty opportunity; initial market entry targeted in Latin America in 2027, U.S. expansion in 2028, and India/Asia closer to 2030. Management is targeting 5–7 million acres in the Americas as initial scale.
Regulatory Progress and Market Access
Key regulatory wins include EU political agreement on new genomic techniques (plenary vote expected in late April 2026), UK PBO framework live (first PBO filings submitted in Jan 2026), 17 positive USDA APHIS determinations, California authorization for gene-edited rice planting, Ecuador and Peru confirmation of equivalence to conventional breeding — collectively accelerating commercial conversations globally.
Technology Performance Improvements
Rice editing efficiency improved by an 'order of magnitude' in 2025 (~10x), enabling faster, more predictable edits (12–15 month cycle to return elite germplasm). Platform progress across multiple crops (canola HT2 positive field results, sclerotinia resistance, pod-shatter trials, wheat single-cell regeneration, improved soybean editing rates) increases partnership optionality.
First Sustainable Ingredients Revenue and Commercialization Path
Received first customer payment from the sustainable ingredients (biofragrance) program and reported an initial commercial sale; company is formalizing an expanded partnership and targeting commercial-scale production as a near-term revenue stream.
Partnerships and Commercial Frameworks
Entered a non-binding LOI with Interox (framework to commercialize herbicides on rice in Ecuador and Colombia in 2027) and signed agreements with regional seed partners (e.g., Semiano, Semias del Hula). Selected by UK DEFRA-funded consortium as gene editing technology partner for light leaf spot resistance in oilseed rape.
Cash Raise and Cost Reductions Extend Runway
Raised $22.3 million in gross proceeds from a public offering in January 2026. Cash and cash equivalents were $9.9 million at 12/31/2025; management expects existing cash plus recent measures to fund operations into late 2026. Company reduced operating expenses by approximately $10 million for full year 2025.
Negative Updates
Widening Net Loss
Net loss was $31.9 million for the quarter ended 12/31/2025 versus $25.8 million year-ago, an increase of $6.1 million (≈23.6% higher), reflecting continuing operating losses despite cost reductions.
Limited Cash Runway and Near-Term Financing Needs
Despite the Jan 2026 raise, cash at 12/31/2025 was $9.9 million and management expects runway into late 2026 — indicating the company will need to execute near-term revenue milestones or secure further financing to sustain operations beyond that point.
Quarterly Revenue Timing and Collaboration Recognition
Collaboration revenue and earnings in the fourth quarter came in below expectations/consensus due to timing of revenue recognition tied to time-based activities; management characterized shortfall as timing-related but it impacted near-term results.
High Royalty Liability Interest Expense and Non-Operating Pressure
Royalty liability interest expense was $9.4 million for the quarter versus $8.2 million a year ago (↑$1.2 million, ≈14.6%). Non-operating income was nominal in the quarter versus $400k in the year-ago period, driven by fair value adjustments to liability-classified warrants.
Ongoing Need to Convert Regulatory Momentum into Sales
While regulatory progress is substantial, commercial launches remain contingent on additional steps (e.g., chemical registrations, definitive commercial agreements). Interlocutor negotiations and expected definitive agreements are targeted for late 2026; commercialization in 2027 depends on successful completion of these milestones.
Operational Restructuring and Workforce Reductions
Consolidation of facilities (Oberlin to San Diego, wind-down of Minnesota site) and workforce reductions were implemented to reduce cash burn — actions that reflect prior cost pressures and could have near-term integration and execution risks.
Company Guidance
Cibus guided that it has $9.9M cash on hand (12/31/2025) and raised $22.3M gross in Jan‑2026, providing runway into late‑2026 (Q3) while targeting to cut annual net cash usage to ≈$30M or less in 2026 after ~ $10M of 2025 R&D/SG&A savings; Q4 expenses were R&D $9.4M, SG&A $5.1M, royalty interest $9.4M, and net loss $31.9M. Key commercial milestones: initial Latin America market entry targeted for 2027 (Interox LOI, definitive agreement expected late‑2026), potential U.S. expansion in 2028 and India/Asia around 2030, seven rice customers representing >$200M potential annual royalties targeting 5–7M acres in the Americas (India ≈120M acres could add ~another $200M), and a 12–15 month edit turnaround; sustainable ingredients/biofragrance commercialization and scale are expected near term (discussed a possible $20–$40M/year ramp). Regulatory catalysts highlighted include an EU NGT plenary vote expected late April 2026, UK PBO filings (submitted Jan), 17 USDA APHIS positive determinations, and favorable rulings in Ecuador and Peru.

Cibus Financial Statement Overview

Summary
Financials reflect an early-stage biotech with very small/volatile revenue, persistent large net losses (2025 net loss ~$127.1M), and continued cash burn (2025 FCF about -$51.2M). Balance-sheet leverage is not extreme (~$33.0M debt), but equity has eroded sharply (to ~$21.8M in 2025), increasing dilution/financing risk.
Income Statement
18
Very Negative
Revenue is very small and volatile (roughly $0.2M–$25.9M historically, down to $3.6M in 2025), and the business remains deeply unprofitable with large operating losses and net losses each year (2025 net loss of about $127.1M). While gross profit improved versus earlier years (and was strong in 2023–2024), the overall earnings profile is weak due to heavy expense levels relative to revenue and a deterioration in revenue growth in 2025.
Balance Sheet
34
Negative
Leverage is moderate in absolute dollars (total debt ~$33.0M in 2025), but the equity base has fallen sharply over time (stockholders’ equity down from ~$293.5M in 2023 to ~$21.8M in 2025), which meaningfully reduces financial flexibility. With assets still sizable (~$305.0M in 2025), the main balance-sheet concern is the rapid erosion of equity from ongoing losses, increasing the risk of future dilution or tighter funding options.
Cash Flow
22
Negative
Cash generation is consistently negative, with operating cash flow and free cash flow remaining meaningfully below zero every year (2025 operating cash flow about -$50.6M and free cash flow about -$51.2M). Free cash flow also deteriorated again in 2025 versus 2024, indicating continued cash burn and ongoing reliance on external financing to fund operations.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue3.64M4.26M1.82M157.00K25.99M
Gross Profit-2.28M4.26M1.42M-1.38M-2.57M
EBITDA-61.54M-241.63M-314.58M-15.21M-25.43M
Net Income-127.08M-251.39M-267.63M-16.89M-29.20M
Balance Sheet
Total Assets305.05M350.07M544.41M22.42M37.19M
Cash, Cash Equivalents and Short-Term Investments9.92M14.43M32.70M3.43M13.82M
Total Debt267.96M36.29M24.62M13.91M17.88M
Total Liabilities283.22M252.24M206.12M15.19M23.06M
Stockholders Equity21.83M92.16M293.47M7.23M14.13M
Cash Flow
Free Cash Flow-51.17M-58.85M-50.53M-20.88M-19.31M
Operating Cash Flow-50.59M-58.04M-46.21M-19.36M-18.81M
Investing Cash Flow-578.00K-808.00K55.06M-1.52M11.20M
Financing Cash Flow46.65M40.60M20.32M9.99M3.74M

Cibus Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price3.68
Price Trends
50DMA
2.65
Negative
100DMA
2.09
Positive
200DMA
1.79
Positive
Market Momentum
MACD
0.08
Positive
RSI
38.45
Neutral
STOCH
1.82
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CBUS, the sentiment is Neutral. The current price of 3.68 is above the 20-day moving average (MA) of 3.47, above the 50-day MA of 2.65, and above the 200-day MA of 1.79, indicating a neutral trend. The MACD of 0.08 indicates Positive momentum. The RSI at 38.45 is Neutral, neither overbought nor oversold. The STOCH value of 1.82 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for CBUS.

Cibus Risk Analysis

Cibus disclosed 50 risk factors in its most recent earnings report. Cibus reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cibus Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$171.61M-6.26-236.85%-8.64%85.68%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$389.14M-2.14-115.27%2925.73%-294.29%
47
Neutral
$37.22M-2.65-76.78%-38.81%-76.96%
42
Neutral
$80.65M-7.23
41
Neutral
$31.04M-6.26-88.89%56.52%75.22%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CBUS
Cibus
2.48
0.43
20.98%
CRVO
CervoMed
4.02
-10.27
-71.87%
XFOR
X4 Pharmaceuticals
4.28
-4.94
-53.58%
ABVC
ABVC BioPharma
1.22
0.53
76.81%
OKYO
OKYO Pharma Limited Sponsored ADR
1.57
0.22
16.30%

Cibus Corporate Events

Private Placements and Financing
Cibus Announces Underwritten Public Offering of Common Stock
Neutral
Jan 30, 2026

On January 29, 2026, Cibus, Inc. entered into an underwriting agreement with BTIG, LLC for an underwritten public offering of 13,333,333 shares of its Class A common stock at $1.50 per share, with company board members participating for 1,000,000 shares at the offering price and a 30-day option granted to the underwriter to purchase up to an additional 1,999,999 shares. The deal, expected to close on or about January 30, 2026 subject to customary conditions, is projected to raise approximately $17.8 million in net proceeds, or $20.5 million if the overallotment option is fully exercised, and includes standard indemnification, a 60-day lock-up agreement for the company and its leadership, and a 6.25% underwriting discount plus reimbursement of the underwriter’s documented expenses, underscoring Cibus’s continued reliance on equity markets to secure funding while temporarily restricting insider share sales.

The most recent analyst rating on (CBUS) stock is a Sell with a $1.50 price target. To see the full list of analyst forecasts on Cibus stock, see the CBUS Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
Cibus streamlines operations to focus on rice traits
Positive
Jan 28, 2026

In 2025, Cibus undertook a significant operational streamlining to concentrate capital and resources on commercializing its weed management traits for rice, including a workforce reduction of about 34 employees approved in July 2025 and completed by year-end, consolidation of core operations in San Diego, and deferral of non-partner-funded non-rice activities. Management estimates its rice herbicide tolerance traits could ultimately generate more than $200 million in annual royalties across initial target markets in Latin America and the United States, while its sustainable ingredients initiatives—particularly a yeast fermentation biofragrance program that began generating nominal payments in 2025—could reach $20–40 million in annual revenue over the long term; combined with cost-cutting measures expected to lower annual net cash usage to about $30 million or less in 2026, these moves aim to bolster financial stability while preserving upside from a broader trait portfolio that Cibus plans to advance opportunistically through partner-funded projects.

The most recent analyst rating on (CBUS) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on Cibus stock, see the CBUS Stock Forecast page.

Stock Buyback
Cibus executes minor internal Class A share repurchase
Neutral
Jan 6, 2026

On December 31, 2025, Cibus, Inc. repurchased 60,088 shares of its Class A common stock from employee Anthony Moran at a nominal price of $0.0001 per share, under a share purchase agreement approved by the board of directors. The transaction represents a small, board-sanctioned internal equity reallocation involving an employee shareholder, with limited apparent impact on the company’s broader capital structure or external stakeholders.

The most recent analyst rating on (CBUS) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on Cibus stock, see the CBUS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 19, 2026