Inozyme Pharma (INZY) AI Stock Analysis

• Market Cap: $258.25M
• Dividend Yield: N/A
• Average Volume (3M): 1.16M
• Price to Earnings (P/E): ―
• Beta (1Y): 4.45
• Revenue Growth: N/A
• EPS Growth: -17.06%
• Country: US
• Employees: 67
• Sector: Healthcare
• Sector Strength: 40
• Industry: Biotechnology
• EPS (TTM): -0.44
• Shares Outstanding: 64,562,000
• 10 Day Avg. Volume: 979,495
• 30 Day Avg. Volume: 1,157,976
• PEG Ratio: 0.02
• Price to Book (P/B): 0.33
• Price to Sales (P/S): 0.00
• P/FCF Ratio: -0.68
• Enterprise Value/Market Cap: 0.05
• Enterprise Value/Revenue: N/A
• Enterprise Value/Gross Profit: -69.30
• Enterprise Value/Ebitda: -0.04
• 1Y Price Target: $7.50
• Price Target Upside: 87.50% Upside
• Rating Consensus: Hold
• Number of Analyst Covering: 8

• Rating: 37 Underperform
• Price Target: ―

Inozyme Pharma's stock score reflects its early-stage biotechnology status with significant operational losses, zero revenue, and ongoing cash burn. Technical indicators show short-term momentum but highlight potential overbought conditions. The negative P/E ratio underscores the lack of profitability, and with no earnings data or corporate events provided, the score is primarily driven by weak financial performance.

Positive Factors

Acquisition Strategy

The acquisition of Inozyme Pharma by BMRN is expected to strengthen BMRN's enzyme replacement therapy portfolio with the addition of INZ-701.

Clinical Development

Recent interim data from INZY showed a significant increase in a key phosphate biomarker, which is seen as derisking future clinical endpoints and enhancing the potential for regulatory approval.

Market Valuation

The deal for Inozyme Pharma, Inc. reflects a 182% premium to the previous closing price, indicating the perceived value and potential of INZY's assets.

Negative Factors

Financial Risks

The acquisition price is considered discounted likely due to risks associated with adult opportunities and cash overhang.

Financing Challenges

Inozyme required capital ahead of pivotal data and faced a difficult financing environment.

Inozyme Pharma Business Overview & Revenue Model

Company Description

Inozyme Pharma (INZY) is a biopharmaceutical company focused on developing novel therapeutics for the treatment of rare diseases characterized by abnormal mineralization. The company aims to address conditions that lead to significant morbidities and mortality due to a lack of effective treatments. Inozyme Pharma's core product candidates target enzyme deficiencies that cause abnormal mineralization in the body, impacting bones, blood vessels, and soft tissues.

How the Company Makes Money

Inozyme Pharma makes money primarily through the development and commercialization of its proprietary therapies aimed at treating rare mineralization disorders. The company's revenue model includes potential income from product sales, should its therapies receive regulatory approval and reach the market. Additionally, Inozyme may engage in partnerships or collaborations with larger pharmaceutical companies to co-develop products or out-license their technologies, which could provide upfront payments, milestone payments, and royalties. As a company focused on clinical-stage development, Inozyme may also receive funding through research grants and investments to support ongoing clinical trials and further drug development.

Inozyme Pharma Financial Statement Overview

Summary

Inozyme Pharma is in a typical early-stage biotechnology phase, characterized by zero revenue and significant operational losses. While its cash reserves and manageable debt levels provide some financial resilience, the ongoing negative cash flows and lack of revenue generation highlight the need for successful product development and commercialization to ensure long-term viability.

Income Statement

Inozyme Pharma has consistently reported zero revenue over the years, indicating its early-stage status typical in biotechnology. The company has faced increasing EBIT and net income losses over the years, highlighting challenges in managing operational efficiency and profitability.

Balance Sheet

The company has a relatively low debt-to-equity ratio, suggesting prudent leverage management. However, declining stockholders' equity and increasing liabilities could pose risks to financial stability. Despite this, the company maintains a healthy cash position.

Cash Flow

Operating cash flow has become increasingly negative over the years, reflecting operational cash burn, which is common in biotech firms without revenue. Despite negative free cash flow, the company has managed to raise significant financing cash flows, mitigating liquidity concerns temporarily.

Breakdown	TTM	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020
Income Statement
Total Revenue	0.00	0.00	0.00	0.00	0.00	0.00
Gross Profit	-195.00K	0.00	-1.29M	-1.18M	-1.05M	-217.00K
EBITDA	-100.34M	-104.03M	-74.81M	-65.88M	-55.97M	-56.82M
Net Income	-106.72M	-102.02M	-71.17M	-65.45M	-56.41M	-55.84M
Balance Sheet
Total Assets	95.16M	123.18M	200.85M	139.19M	123.54M	169.36M
Cash, Cash Equivalents and Short-Term Investments	84.78M	113.09M	188.59M	127.87M	111.80M	159.90M
Total Debt	26.37M	46.87M	46.59M	6.78M	3.37M	1.29M
Total Liabilities	63.37M	65.36M	60.37M	20.80M	14.27M	11.26M
Stockholders Equity	31.80M	57.83M	140.48M	118.59M	109.27M	158.10M
Cash Flow
Free Cash Flow	-96.55M	-91.97M	-70.97M	-58.17M	-48.55M	-36.54M
Operating Cash Flow	-96.52M	-91.91M	-70.67M	-57.76M	-48.15M	-35.97M
Investing Cash Flow	90.29M	67.00M	-53.65M	-5.40M	42.80M	-117.18M
Financing Cash Flow	11.47M	11.40M	125.97M	72.79M	609.00K	149.81M

Inozyme Pharma Technical Analysis

• Technical Analysis Sentiment: Positive
• Last Price: 4.00
• 50DMA: Positive
• 100DMA: Positive
• 200DMA: Positive
• MACD: Positive
• RSI: Negative
• STOCH: Negative

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For INZY, the sentiment is Positive. The current price of 4 is above the 20-day moving average (MA) of 3.99, above the 50-day MA of 3.03, and above the 200-day MA of 2.76, indicating a bullish trend. The MACD of 0.22 indicates Positive momentum. The RSI at 82.70 is Negative, neither overbought nor oversold. The STOCH value of 100.00 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for INZY.

Inozyme Pharma Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
PYXS	47 Neutral	$70.00M	―	-66.30%	―	―	30.51%
ADAP	47 Neutral	$74.78M	―	-273.36%	―	883.05%	62.93%
Sector *	46 Neutral	C$200.02M	-3.36	-23.14%	1.86%	20.75%	-0.36%
IOBT	43 Neutral	$128.47M	―	-138.78%	―	―	32.77%
INO	43 Neutral	$73.89M	―	-132.44%	―	-60.52%	42.41%
VTVT	38 Underperform	$51.58M	―	-130.16%	―	―	65.54%
INZY	37 Underperform	$258.25M	―	-141.69%	―	―	-17.06%

Inozyme Pharma Corporate Events

Inozyme Pharma Advances with Promising Trial Results

Inozyme Pharma announced positive interim results for its INZ-701 treatment from the ENERGY 1 trial and Expanded Access Program, demonstrating improved survival rates, reduced arterial calcifications, and improved heart function in infants and young children with ENPP1 Deficiency. The company completed enrollment in the ENERGY 3 pivotal trial and received regulatory guidance for the upcoming ASPIRE pivotal trial focused on ABCC6 Deficiency in children, highlighting significant advancements in their therapeutic programs and underscoring the potential impact on addressing unmet medical needs in these patient populations.