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Inozyme Pharma (INZY)
NASDAQ:INZY
US Market

Inozyme Pharma (INZY) AI Stock Analysis

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Inozyme Pharma

(NASDAQ:INZY)

44Neutral
Inozyme Pharma's overall stock score reflects its early-stage biotechnology status, with no revenue and significant operational losses. Despite having manageable debt and reasonable cash reserves, the company's financial performance is weak. The technical analysis indicates some short-term buying interest, but the stock remains below key long-term averages, signaling caution. Valuation metrics are less meaningful due to the negative earnings, highlighting the speculative nature of this investment.
Positive Factors
Clinical Trial Progress
INZ-701 is in Phase 3 development, indicating progress in clinical trials for ENPP1 Deficiency treatment.
Interim Data
Inozyme announced positive interim data from its global, open-label Phase 1b ENERGY-1 trial and Expanded Access Program evaluating INZ-701 in infants and young children with ENPP1 Deficiency.
Regulatory Designation
INZ-701 has orphan drug designation from the EMA and the FDA for the treatment of ENPP1 Deficiency.
Negative Factors
Financial Performance
Inozyme reported Q4 results including a $27MM net loss and net cash of $113MM.
Price Target Adjustment
Lowering the price target to $15 from $23.
Workforce Reduction
De-prioritization of the ABCC6 and Calciphylaxis programs and a ~25% workforce reduction to conserve cash.

Inozyme Pharma (INZY) vs. S&P 500 (SPY)

Inozyme Pharma Business Overview & Revenue Model

Company DescriptionInozyme Pharma, Inc., a rare disease biopharmaceutical company, engages in developing therapeutics for treating abnormal mineralization impacting the vasculature, soft tissue, and skeleton diseases. The company's lead product candidate is INZ-701, a soluble, recombinant protein to treat the rare genetic diseases of ENPP1 and ABCC6 deficiencies, as well as for the treatment of calciphylaxis. It has a license agreement with Yale University for specified therapeutic and prophylactic products. Inozyme Pharma, Inc. was incorporated in 2015 and is headquartered in Boston, Massachusetts.
How the Company Makes MoneyInozyme Pharma makes money primarily through the development and commercialization of its proprietary therapies aimed at treating rare mineralization disorders. The company's revenue model includes potential income from product sales, should its therapies receive regulatory approval and reach the market. Additionally, Inozyme may engage in partnerships or collaborations with larger pharmaceutical companies to co-develop products or out-license their technologies, which could provide upfront payments, milestone payments, and royalties. As a company focused on clinical-stage development, Inozyme may also receive funding through research grants and investments to support ongoing clinical trials and further drug development.

Inozyme Pharma Financial Statement Overview

Summary
Inozyme Pharma is in a typical early-stage biotechnology phase, characterized by zero revenue and significant operational losses. While its cash reserves and manageable debt levels provide some financial resilience, the ongoing negative cash flows and lack of revenue generation highlight the need for successful product development and commercialization to ensure long-term viability.
Income Statement
20
Very Negative
Inozyme Pharma has consistently reported zero revenue over the years, indicating its early-stage status typical in biotechnology. The company has faced increasing EBIT and net income losses over the years, highlighting challenges in managing operational efficiency and profitability.
Balance Sheet
40
Negative
The company has a relatively low debt-to-equity ratio, suggesting prudent leverage management. However, declining stockholders' equity and increasing liabilities could pose risks to financial stability. Despite this, the company maintains a healthy cash position.
Cash Flow
35
Negative
Operating cash flow has become increasingly negative over the years, reflecting operational cash burn, which is common in biotech firms without revenue. Despite negative free cash flow, the company has managed to raise significant financing cash flows, mitigating liquidity concerns temporarily.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
0.000.000.000.000.00
Gross Profit
0.00-1.29M-1.18M-1.05M-217.00K
EBIT
-104.03M-75.64M-68.67M-56.65M-57.04M
EBITDA
-104.03M-74.81M-65.88M-55.97M-56.82M
Net Income Common Stockholders
-102.02M-71.17M-65.45M-56.41M-55.84M
Balance SheetCash, Cash Equivalents and Short-Term Investments
113.09M188.59M127.87M111.80M159.90M
Total Assets
123.18M200.85M139.19M123.54M169.36M
Total Debt
15.41M46.59M6.78M3.37M1.29M
Net Debt
-5.67M12.00M-26.14M-19.95M-158.61M
Total Liabilities
65.36M60.37M20.80M14.27M11.26M
Stockholders Equity
57.83M140.48M118.59M109.27M158.10M
Cash FlowFree Cash Flow
-91.97M-70.97M-58.17M-48.55M-36.54M
Operating Cash Flow
-91.91M-70.67M-57.76M-48.15M-35.97M
Investing Cash Flow
67.00M-53.65M-5.40M42.80M-117.18M
Financing Cash Flow
11.40M125.97M72.79M609.00K149.81M

Inozyme Pharma Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1.15
Price Trends
50DMA
1.03
Positive
100DMA
1.57
Negative
200DMA
3.18
Negative
Market Momentum
MACD
<0.01
Negative
RSI
62.25
Neutral
STOCH
67.79
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For INZY, the sentiment is Positive. The current price of 1.15 is above the 20-day moving average (MA) of 0.95, above the 50-day MA of 1.03, and below the 200-day MA of 3.18, indicating a neutral trend. The MACD of <0.01 indicates Negative momentum. The RSI at 62.25 is Neutral, neither overbought nor oversold. The STOCH value of 67.79 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for INZY.

Inozyme Pharma Risk Analysis

Inozyme Pharma disclosed 81 risk factors in its most recent earnings report. Inozyme Pharma reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Inozyme Pharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$5.38B3.59-41.63%2.87%17.72%1.87%
45
Neutral
$70.82M-273.36%194.23%45.50%
44
Neutral
$61.96M-102.90%-17.06%
43
Neutral
$62.59M-106.00%32.77%
42
Neutral
$67.75M-62.75%30.51%
38
Underperform
$73.90M-121.97%65.54%
ININO
33
Underperform
$69.31M-115.42%-73.83%34.81%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
INZY
Inozyme Pharma
1.15
-3.50
-75.27%
INO
Inovio Pharmaceuticals
1.94
-10.07
-83.85%
ADAP
Adaptimmune Therapeutics
0.28
-0.91
-76.47%
VTVT
vTv Therapeutics
19.95
-3.75
-15.82%
PYXS
Pyxis Oncology
1.10
-3.31
-75.06%
IOBT
IO Biotech
0.97
-0.56
-36.60%

Inozyme Pharma Corporate Events

Product-Related AnnouncementsBusiness Operations and Strategy
Inozyme Pharma Advances with Promising Trial Results
Positive
Jan 10, 2025

Inozyme Pharma announced positive interim results for its INZ-701 treatment from the ENERGY 1 trial and Expanded Access Program, demonstrating improved survival rates, reduced arterial calcifications, and improved heart function in infants and young children with ENPP1 Deficiency. The company completed enrollment in the ENERGY 3 pivotal trial and received regulatory guidance for the upcoming ASPIRE pivotal trial focused on ABCC6 Deficiency in children, highlighting significant advancements in their therapeutic programs and underscoring the potential impact on addressing unmet medical needs in these patient populations.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.