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vTv Therapeutics (VTVT)
NASDAQ:VTVT

vTv Therapeutics (VTVT) AI Stock Analysis

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VTVT

vTv Therapeutics

(NASDAQ:VTVT)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$40.00
▲(12.39% Upside)
The score is held down primarily by weak financial performance (minimal revenue, large losses, and consistent cash burn) despite low leverage. Technicals provide meaningful support due to a clear uptrend and positive momentum indicators, while valuation is constrained by negative earnings and no dividend support.
Positive Factors
Low Leverage
Very low reported debt (TTM ~$0.36M) and minimal debt-to-equity materially reduce near-term financial risk and interest burden, giving management structural flexibility to prioritize clinical development and capital allocation even while operating at a loss.
Access to Capital / Equity Strength
Equity turning positive and rising to roughly $70.5M TTM indicates successful financings and provides a meaningful runway. Durable access to capital markets supports multi-quarter clinical programs and makes it easier to fund trials or attract partners without immediate commercial revenue.
Focused Clinical Pipeline
A concentrated small-molecule pipeline targeting metabolic and type 2 diabetes aligns with a large, chronic market and established development pathways. This strategic focus improves partnerability and, if trials succeed, offers durable commercial opportunity in a structurally growing therapeutic area.
Negative Factors
Minimal Revenue
With TTM revenue near $17K and negative gross profit, the company has no meaningful product-derived cash inflows. Lack of commercial revenue is a structural weakness: it prevents self-funding of development and forces continuous reliance on external financing to sustain operations.
Sustained Cash Burn
Persistent negative operating cash flow (~-$20.8M TTM) and negative free cash flow show structural cash consumption to run trials. Ongoing burn necessitates repeated capital raises, raising dilution risk and the chance of program delays if market conditions or investor appetite tighten.
Dependence on External Funding
Business model depends on equity offerings, milestone payments, and partnerships rather than recurring sales. That creates durable revenue and timing uncertainty: program progress and deal execution, not predictable cash flows, will determine sustainability and long-term execution risk.

vTv Therapeutics (VTVT) vs. SPDR S&P 500 ETF (SPY)

vTv Therapeutics Business Overview & Revenue Model

Company DescriptionvTv Therapeutics Inc., a clinical-stage biopharmaceutical company, focuses on the development of orally administered treatments for diabetes. The company is developing TTP399, an orally administered, small molecule, and liver-selective glucokinase activator for the treatment of type 1 diabetes; and HPP737, an orally administered non-CNS penetrant phosphodiesterase type 4 (PDE4) inhibitor that addresses inflammatory diseases and psoriasis. It is also involved in the clinical development of other programs, including TTP273, an oral small molecule GLP-1 receptor agonist for postprandial glucose excursion to treat cystic fibrosis related diabetes; HPP3033, a non-electrophilic therapeutic approach to activating the Nrf2 pathway for the treatment of chronic diseases associated with oxidative stress; azeliragon, a RAGE antagonist for inflammatory lung diseases, including severe COVID-19, as well as for pancreatic and breast cancers; and HPP971, an Nrf2 activator for renal diseases through partnerships with pharmaceutical partners. The company has a license agreement with Reneo Pharmaceuticals, Inc. to develop and commercialize peroxisome proliferation activated receptor delta agonist program, including the compound HPP593. vTv Therapeutics Inc. also has license and research agreements with Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.; Newsoara Biopharma Co., Ltd.; JDRF International; and Novo Nordisk A/S. The company was incorporated in 2015 and is headquartered in High Point, North Carolina. vTv Therapeutics Inc. is a subsidiary of MacAndrews & Forbes Incorporated.
How the Company Makes MoneyvTv Therapeutics primarily generates revenue through partnerships and collaborations with other pharmaceutical companies. These collaborations often involve licensing agreements, wherein vTv licenses its proprietary drug candidates or technology platforms to partners in exchange for upfront payments, milestone payments based on development progress, and potential royalties on future sales. The company may also receive funding support through research grants and government incentives aimed at fostering innovation in the biopharmaceutical field. Additionally, vTv Therapeutics may engage in strategic alliances to co-develop and commercialize certain products, thereby sharing the financial risks and rewards associated with drug development.

vTv Therapeutics Financial Statement Overview

Summary
Financial profile is weak: revenue is essentially negligible, gross profit is negative, and the company remains deeply loss-making with sizable operating losses and ongoing cash burn. Balance-sheet risk is helped by very low debt and improved reported equity, but the business still relies on external funding due to persistent negative profitability and free cash flow.
Income Statement
12
Very Negative
Results remain deeply loss-making with very weak profitability in both annual periods and TTM (Trailing-Twelve-Months). TTM revenue is essentially de minimis ($17K) and gross profit is negative, while operating losses are large (TTM EBIT about -$29.8M) and net losses remain substantial (TTM net income about -$23.5M). Revenue has not shown a sustained growth trajectory (including a year with zero revenue), and margins are highly negative, indicating limited operating leverage at the current scale. A modest positive is that losses have not consistently worsened every year, but overall earnings quality and visibility remain weak.
Balance Sheet
46
Neutral
Leverage is low, with minimal total debt across periods (TTM total debt about $0.36M) and a very low debt-to-equity level in the most recent balance sheets, reducing near-term financial risk from borrowing. However, the equity picture has been volatile—stockholders’ equity was negative in multiple years before turning positive in 2024 and rising sharply in TTM (about $70.5M), suggesting meaningful financing activity and/or accounting step-ups rather than internally generated profitability. Returns on equity are very weak given ongoing losses, and the company remains dependent on external capital while it operates at a significant deficit.
Cash Flow
18
Very Negative
Cash generation remains a key weakness. Operating cash flow is consistently negative (TTM operating cash flow about -$20.8M), and free cash flow is equally negative, indicating ongoing cash burn to fund operations. While the burn rate improved versus 2024 (less negative in TTM), the longer-run trend is uneven and includes periods of higher outflows. Free cash flow is roughly in line with net losses, which suggests losses translate into cash burn rather than being primarily non-cash—raising the importance of funding access.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue17.00K1.02M0.002.02M4.00M6.41M
Gross Profit-5.00K1.02M0.002.02M4.00M-4.60M
EBITDA-28.96M-22.52M-25.86M-24.77M-17.52M-12.02M
Net Income-23.47M-18.46M-20.25M-19.16M-12.99M-8.50M
Balance Sheet
Total Assets99.49M38.27M11.02M33.24M25.47M14.79M
Cash, Cash Equivalents and Short-Term Investments98.50M36.75M9.45M12.13M13.41M5.75M
Total Debt360.00K169.00K529.00K716.00K932.00K915.00K
Total Liabilities28.95M23.96M29.57M27.40M10.25M11.00M
Stockholders Equity70.54M12.20M-24.68M-10.74M-9.74M-80.10M
Cash Flow
Free Cash Flow-20.83M-25.31M-19.08M-15.27M-19.31M-18.00M
Operating Cash Flow-20.83M-25.31M-19.08M-15.25M-19.31M-18.00M
Investing Cash Flow0.000.004.40M-21.00K0.000.00
Financing Cash Flow77.76M52.61M12.00M13.98M26.98M19.47M

vTv Therapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price35.59
Price Trends
50DMA
33.08
Positive
100DMA
27.01
Positive
200DMA
22.13
Positive
Market Momentum
MACD
1.31
Positive
RSI
48.24
Neutral
STOCH
44.97
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For VTVT, the sentiment is Neutral. The current price of 35.59 is below the 20-day moving average (MA) of 38.22, above the 50-day MA of 33.08, and above the 200-day MA of 22.13, indicating a neutral trend. The MACD of 1.31 indicates Positive momentum. The RSI at 48.24 is Neutral, neither overbought nor oversold. The STOCH value of 44.97 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for VTVT.

vTv Therapeutics Risk Analysis

vTv Therapeutics disclosed 62 risk factors in its most recent earnings report. vTv Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

vTv Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$148.73M-10.71-54.87%-98.30%26.62%
52
Neutral
$92.38M-3.04-63.41%-87.59%11.53%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$59.48M-1.49-49.17%23.37%
43
Neutral
$67.13M-0.95
42
Neutral
$79.27M-0.45-64.27%14.19%
41
Neutral
$58.41M-4.63-42.68%63.85%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
VTVT
vTv Therapeutics
35.59
21.63
154.94%
ATHE
Alterity Therapeutics
3.45
-0.04
-1.15%
IFRX
InflaRx
1.00
-1.47
-59.51%
CLNN
Clene
5.05
0.25
5.21%
PLRX
Pliant Therapeutics
1.29
-9.78
-88.35%
ADAG
Adagene
1.96
0.19
10.73%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 15, 2026