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Alterity Therapeutics Ltd (ATHE)
NASDAQ:ATHE
US Market

Alterity Therapeutics (ATHE) AI Stock Analysis

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ATHE

Alterity Therapeutics

(NASDAQ:ATHE)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
$3.50
▼(-1.41% Downside)
Action:ReiteratedDate:02/07/26
The score is primarily held back by persistent unprofitability and negative operating/free cash flow despite strong gross margins and solid recent revenue growth. Technicals are mixed—some near-term strength above shorter moving averages, but weaker longer-term trend signals—and valuation is constrained by negative earnings and no dividend support.
Positive Factors
Innovative Drug Development
Alterity's unique approach to treating neurodegenerative diseases positions it as a leader in innovation, potentially leading to breakthrough therapies and a competitive edge in the biotechnology sector.
Positive Clinical Trial Results
Successful Phase 2 results for ATH434 enhance Alterity's credibility and market potential in treating Multiple System Atrophy, supporting long-term growth and market leadership.
Strong Revenue Growth
High gross profit margins indicate effective cost management and strong revenue growth, which are critical for sustaining operations and funding future R&D activities.
Negative Factors
Profitability Challenges
Persistent unprofitability raises concerns about Alterity's ability to sustain operations and invest in future growth, posing a risk to long-term viability.
Negative Cash Flows
Negative cash flows indicate liquidity issues, potentially limiting Alterity's ability to fund ongoing research and development, impacting its growth trajectory.
High Operational Risk
Ongoing operational losses and cash flow issues increase financial risk, potentially affecting Alterity's ability to achieve long-term strategic goals and maintain competitive positioning.

Alterity Therapeutics (ATHE) vs. SPDR S&P 500 ETF (SPY)

Alterity Therapeutics Business Overview & Revenue Model

Company DescriptionAlterity Therapeutics (ATHE) is a biotechnology company focused on developing innovative therapies for neurodegenerative diseases, particularly in the realm of protein misfolding disorders. The company operates primarily in the healthcare sector, leveraging its proprietary drug development platform to create novel treatments aimed at addressing unmet medical needs in conditions such as Alzheimer's disease and Parkinson's disease. Alterity's core pipeline includes drug candidates that target specific molecular mechanisms involved in these disorders, with the goal of improving patient outcomes and quality of life.
How the Company Makes MoneyAlterity Therapeutics generates revenue primarily through the development and commercialization of its pharmaceutical products. The company may receive funding through various channels, including government grants, partnerships with larger pharmaceutical firms, and licensing agreements for its drug candidates. Additionally, Alterity could potentially earn revenue through milestone payments and royalties from any successful drug sales once they are commercialized. Collaborations with biotech or pharmaceutical companies can also provide financial support and resources, which help sustain its research and development efforts.

Alterity Therapeutics Financial Statement Overview

Summary
Very strong gross margins and notable recent revenue growth, but profitability remains weak with negative net profit/EBIT margins and continued losses. Low leverage helps, yet negative operating and free cash flow raise sustainability and funding-risk concerns.
Income Statement
45
Neutral
Alterity Therapeutics shows a strong gross profit margin, consistently above 90%, indicating effective cost management relative to revenue. However, the company struggles with profitability, as evidenced by negative net profit and EBIT margins. Despite a notable revenue growth rate of 46% in the latest year, the company remains unprofitable, which is a concern for long-term sustainability.
Balance Sheet
50
Neutral
The balance sheet reflects a low debt-to-equity ratio, suggesting minimal leverage and a conservative capital structure. However, the return on equity is negative, indicating that the company is not generating sufficient returns on its equity base. The equity ratio is relatively stable, but the negative ROE highlights profitability challenges.
Cash Flow
40
Negative
Cash flow analysis reveals negative operating and free cash flows, which are concerning for liquidity and operational sustainability. The free cash flow to net income ratio is consistently around 1, indicating that cash flow is closely aligned with net income, albeit both are negative. The company needs to improve cash generation to support its operations and growth.
BreakdownJun 2025Jun 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue5.44M4.02M3.92M5.12M4.34M
Gross Profit5.31M3.80M3.63M4.76M3.98M
EBITDA-14.63M-19.57M-14.60M-17.39M-15.16M
Net Income-12.15M-19.12M-13.81M-12.85M-15.31M
Balance Sheet
Total Assets46.03M19.22M27.32M41.36M33.59M
Cash, Cash Equivalents and Short-Term Investments40.66M12.64M15.77M34.81M28.12M
Total Debt155.46K159.04K210.38K117.49K65.65K
Total Liabilities3.62M5.43M4.50M5.89M3.12M
Stockholders Equity42.40M13.80M22.81M35.47M30.47M
Cash Flow
Free Cash Flow-11.45M-12.61M-20.04M-12.43M-17.34M
Operating Cash Flow-11.45M-12.61M-20.04M-12.34M-17.33M
Investing Cash Flow-7.50M-5.72K-36.46K-89.15K-10.47K
Financing Cash Flow39.67M9.22M124.34K16.30M36.69M

Alterity Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.55
Price Trends
50DMA
3.28
Positive
100DMA
3.66
Negative
200DMA
4.16
Negative
Market Momentum
MACD
0.01
Positive
RSI
46.51
Neutral
STOCH
19.67
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ATHE, the sentiment is Negative. The current price of 3.55 is above the 20-day moving average (MA) of 3.36, above the 50-day MA of 3.28, and below the 200-day MA of 4.16, indicating a neutral trend. The MACD of 0.01 indicates Positive momentum. The RSI at 46.51 is Neutral, neither overbought nor oversold. The STOCH value of 19.67 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ATHE.

Alterity Therapeutics Risk Analysis

Alterity Therapeutics disclosed 44 risk factors in its most recent earnings report. Alterity Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Alterity Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
$171.39M-1.48-63.45%63.31%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$61.16M-4.52-42.68%63.85%
44
Neutral
$136.90M-102.47%66.05%
43
Neutral
$43.81M-0.94-176.32%48.68%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ATHE
Alterity Therapeutics
3.30
-0.81
-19.71%
CVM
Cel-Sci
4.45
-6.31
-58.62%
XBIT
XBiotech
2.34
-0.68
-22.52%
KLRS
Kalaris Therapeutics
10.77
0.99
10.12%
UNCY
Unicycive Therapeutics
6.57
1.15
21.22%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 07, 2026