Clinical Trial SuccessATH434 demonstrated a beneficial effect on orthostatic hypotension, with stabilization from baseline in both the 50mg and 75mg groups compared to a 6-point decline over 52 weeks for placebo.
Financial StrengthAlterity Therapeutics raised substantial funding through a two-tranche financing, potentially providing up to A$40M in additional funding.
Therapeutic AdvancementsNeuroimaging data in 61 patients also confirmed target engagement by ATH434 via reducing iron accumulation at both doses in the globus pallidus, and in the putamen and substantia nigra at the 50 mg dose level.