Metagenomi, Inc. (MGX) AI Stock Analysis

• Market Cap: $85.95M
• Dividend Yield: N/A
• Average Volume (3M): 883.52K
• Price to Earnings (P/E): ―
• Beta (1Y): 0.98
• Revenue Growth: -39.62%
• EPS Growth: 6.83%
• Country: US
• Employees: 202
• Sector: Healthcare
• Sector Strength: 45
• Industry: Biotechnology
• EPS (TTM): -0.54
• Shares Outstanding: 37,533,134
• 10 Day Avg. Volume: 1,405,864
• 30 Day Avg. Volume: 883,524
• PEG Ratio: -0.12
• Price to Book (P/B): 0.58
• Price to Sales (P/S): 2.58
• P/FCF Ratio: -1.20
• Enterprise Value/Market Cap: -1.25
• Enterprise Value/Revenue: -3.17
• Enterprise Value/Gross Profit: -3.17
• Enterprise Value/Ebitda: 1.24
• 1Y Price Target: $9.00
• Price Target Upside: 316.67% Upside
• Rating Consensus: Strong Buy
• Number of Analyst Covering: 3
• EPS Forecast (FY): N/A
• Revenue Forecast (FY): N/A

• Rating: 43 Neutral
• Price Target: $2.00 ▼(-7.41% Downside)

Metagenomi, Inc. faces significant challenges with profitability and cash flow, which are the most impactful factors on its stock score. The technical analysis further indicates bearish momentum, and the valuation metrics suggest limited attractiveness. These factors combined result in a low overall stock score.

Positive Factors

Strong Revenue Growth

The substantial revenue growth reflects successful product adoption and expanding market presence, enhancing long-term business prospects.

Strategic Partnerships

Strategic collaborations provide stable revenue streams and access to broader markets, strengthening competitive positioning and innovation capacity.

Improving Equity Position

A strong equity position indicates financial resilience and improved capital structure, supporting future growth and investment opportunities.

Negative Factors

Profitability Challenges

Continued profitability issues suggest high operational costs, potentially limiting reinvestment and affecting long-term financial health.

Negative Cash Flow

Negative cash flow highlights liquidity challenges, which may constrain operational flexibility and require external financing to sustain operations.

Volatility in Asset Management

Asset management volatility may lead to financial instability, affecting the company's ability to efficiently allocate resources and manage growth.

Metagenomi, Inc. Business Overview & Revenue Model

Company Description

Metagenomi, Inc., a gene editing biotechnology company, develops therapeutics for patients using metagenomics-derived genome editing toolbox in the United States. The company's genome editing toolbox includes programmable nucleases, base editors, and RNA and DNA-mediated integration systems, such as prime editing systems and clustered regularly interspaced short palindromic repeat-associated transposases. It has a strategic collaboration and license agreement with ModernaTX, Inc. focusing on new genome editing system for in vivo human therapeutic applications; a development, option, and license agreement with Affini-T Therapeutics, Inc. to develop and commercialize gene edited T-cell receptor-based therapeutic products in the field of treatment, prevention, or diagnosis of human cancer; and a collaboration and license agreement with Ionis Pharmaceuticals, Inc. to research, develop, and commercialize investigational medicines using genome editing technologies. The company was incorporated in 2016 and is based in Emeryville, California.

How the Company Makes Money

Metagenomi generates revenue through multiple streams, primarily by partnering with pharmaceutical and biotechnology companies to develop and commercialize gene therapies. The company engages in strategic collaborations, licensing agreements, and research partnerships, which provide upfront payments, milestone payments, and royalties on sales of therapeutic products developed using its technology. Additionally, Metagenomi may receive funding from government grants and private investments aimed at advancing its research and development initiatives. Significant partnerships with established firms in the biotech space enhance its revenue potential by expanding its access to markets and resources.

Metagenomi, Inc. Financial Statement Overview

Summary

Metagenomi, Inc. exhibits strong revenue growth but struggles with profitability and cash flow management. The balance sheet shows improving equity but requires careful monitoring of debt levels and liquidity. Overall, the company needs to address its operational and cash flow challenges to sustain its growth trajectory and ensure long-term financial health.

Income Statement

Metagenomi, Inc. has shown substantial revenue growth over the past years, with a remarkable increase from $243K in 2021 to $52.3M in 2024. However, the company is facing significant profitability challenges, as indicated by negative EBIT and net income margins, suggesting high operational costs or investments outpacing revenue growth. The gross profit margin improved significantly, but the net profit margin remains negative, indicating ongoing losses.

Balance Sheet

The company's balance sheet shows a strong equity position with positive stockholders' equity in 2024, recovering from negative equity in previous years. The debt-to-equity ratio is relatively low, reflecting manageable leverage levels. However, the consistent negative equity in earlier years and the volatility in asset management could pose risks to financial stability.

Cash Flow

Metagenomi's cash flow statement highlights significant cash outflows, particularly in operating cash flow, which has been negative and worsening. The free cash flow is also negative, indicating potential liquidity challenges. Despite these concerns, the company has maintained substantial cash balances, possibly from financing activities, but sustainability may be an issue if cash burn continues.

Breakdown	TTM	Dec 2024	Dec 2023	Dec 2022	Dec 2021
Income Statement
Total Revenue	33.77M	52.30M	44.76M	17.20M	243.00K
Gross Profit	33.77M	52.30M	40.55M	15.47M	-144.00K
EBITDA	-86.30M	-83.49M	-74.28M	-39.19M	-20.75M
Net Income	-87.12M	-78.06M	-68.25M	-43.59M	-21.44M
Balance Sheet
Total Assets	272.28M	324.60M	364.84M	414.49M	141.99M
Cash, Cash Equivalents and Short-Term Investments	204.99M	248.31M	271.18M	362.13M	108.15M
Total Debt	42.99M	45.78M	48.23M	18.57M	48.93M
Total Liabilities	76.45M	89.74M	500.43M	488.91M	174.54M
Stockholders Equity	195.83M	234.86M	-135.58M	271.68M	43.95M
Cash Flow
Free Cash Flow	-98.96M	-112.19M	-101.22M	15.75M	21.35M
Operating Cash Flow	-97.01M	-109.07M	-91.41M	29.72M	24.26M
Investing Cash Flow	63.41M	-88.16M	45.73M	-122.20M	-74.32M
Financing Cash Flow	-735.00K	84.01M	1.01M	239.59M	39.92M

Metagenomi, Inc. Technical Analysis

• Technical Analysis Sentiment: Negative
• Last Price: 2.16
• 50DMA: Negative
• 100DMA: Negative
• 200DMA: Positive
• MACD: Positive
• RSI: Neutral
• STOCH: Positive

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MGX, the sentiment is Negative. The current price of 2.16 is below the 20-day moving average (MA) of 2.72, below the 50-day MA of 2.41, and above the 200-day MA of 2.02, indicating a neutral trend. The MACD of -0.09 indicates Positive momentum. The RSI at 38.18 is Neutral, neither overbought nor oversold. The STOCH value of 9.67 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for MGX.

Metagenomi, Inc. Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
Sector *	51 Neutral	$7.86B	-0.30	-43.30%	2.27%	22.53%	-2.21%
ORMP	47 Neutral	$89.80M	―	-14.57%	―	―	-217.26%
MGX	43 Neutral	$85.95M	-0.98	-37.45%	―	-39.62%	6.83%
ATRA	41 Neutral	$82.94M	―	―	―	202.41%	98.99%
HOWL	41 Neutral	$55.33M	-0.74	-122.43%	―	-100.00%	-8.30%
IMUX	37 Underperform	$70.89M	―	-208.93%	―	―	35.46%
CNTX	37 Underperform	$102.90M	―	-33.68%	―	―	69.30%

Metagenomi, Inc. Corporate Events

Metagenomi Regains Control After Affini-T Agreement Termination

On September 29, 2025, Metagenomi, Inc. entered into a Non-Exclusive License Agreement with Acuitas Therapeutics, Inc. to utilize Acuitas’s lipid nanoparticle technology for developing and commercializing genome editing constructs. This agreement involves financial commitments, including maintenance fees, milestone payments, and royalties. The agreement can be terminated under specific conditions. On September 30, 2025, Metagenomi terminated its agreement with Affini-T Therapeutics, regaining full control over its intellectual property and manufacturing rights related to TCR-based therapeutic products, as Affini-T assigned its benefits to creditors. This termination allows Metagenomi to freely operate in previously restricted areas without future payments from Affini-T.

The most recent analyst rating on (MGX) stock is a Hold with a $2.50 price target. To see the full list of analyst forecasts on Metagenomi, Inc. stock, see the MGX Stock Forecast page.

Metagenomi, Inc. Reports Q2 2025 Financial Results

Metagenomi, Inc. is a precision genetic medicines company based in Emeryville, California, specializing in developing curative therapeutics using a proprietary genome editing toolbox derived from metagenomics, primarily operating in the biotechnology sector.

Metagenomi Reports Strong Q2 2025 Financial Results

Metagenomi, Inc. reported its second quarter 2025 financial results and business updates, highlighting significant advancements in its gene editing technologies. The company presented three abstracts at the American Society of Gene & Cell Therapy, showcasing early proof-of-concept data for its gene editing technologies, and announced a strong cash position of $205 million, expected to support operations into 2027. Metagenomi continues to advance its MGX-001 program for Hemophilia A and its collaboration with Ionis in cardiometabolic indications, while also enhancing its board with the appointment of Laurence Reid, Ph.D. The company is focused on operational efficiency and investment in its pipeline and AI-driven metagenomics platform.

The most recent analyst rating on (MGX) stock is a Buy with a $21.00 price target. To see the full list of analyst forecasts on Metagenomi, Inc. stock, see the MGX Stock Forecast page.