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Atara Biotherapeutics Inc (ATRA)
NASDAQ:ATRA

Atara Biotherapeutics (ATRA) AI Stock Analysis

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ATRA

Atara Biotherapeutics

(NASDAQ:ATRA)

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Neutral 42 (OpenAI - 5.2)
,
Neutral 42 (OpenAI - 5.2)
,
Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
$5.50
▼(-65.17% Downside)
Action:ReiteratedDate:03/17/26
The score is weighed down primarily by weak financial quality (negative free cash flow and negative equity) and significant regulatory uncertainty around EBVALLO. Technicals are only modestly supportive in the very near term, while valuation support is limited due to a negative P/E and no dividend.
Positive Factors
Strategic partnership with Pierre Fabre
A commercial partner actively managing the U.S. regulatory engagement (Type A meeting, briefing book submission) meaningfully reduces Atara’s standalone commercialization burden. This durable partnership leverages Pierre Fabre’s regulatory and commercial capabilities and preserves Atara’s optionality while development and resubmission proceed.
Improved 2025 profitability and strong gross margins
A reported swing to net income in 2025 combined with persistently high gross margins supports the structural potential for profitable product economics if approvals and commercial scale are achieved. Reduced debt in 2025 also lowers fixed financing burden, improving long-term financial flexibility versus prior years.
Near-term cash relief via milestone extension and warrant
Extending a $9M milestone payment eases immediate cash outflows and lengthens runway without an immediate equity raise. The warrant issuance aligns counterparty incentives and offers contingent value, providing a durable source of optional liquidity or equity-linked support while regulatory work continues.
Negative Factors
Negative shareholder equity
Negative shareholders’ equity over multiple years is a structural capital-quality issue that erodes financial flexibility. It constrains access to traditional credit, may trigger covenant or supplier concerns, and signals the company has relied on losses and balance-sheet erosion, limiting resilience during protracted development or regulatory delays.
Continued negative operating and free cash flow
Sustained cash burn (material negative operating and free cash flow) necessitates repeated financing or milestone-dependent receipts. This structural cash gap pressures dilution risk, constrains investment in broader pipeline programs, and makes long-term planning contingent on successful partnership milestones or capital markets access.
Regulatory uncertainty from FDA CRL for EBVALLO
A CRL that challenges the adequacy of the pivotal trial is a fundamental barrier to U.S. commercialization. It creates a multi-quarter or multi-year pathway risk that can eliminate expected regulatory milestones and U.S. revenues, forcing reliance on partner resubmission, additional data or alternate regulatory strategies—structural constraints to near-term value realization.

Atara Biotherapeutics (ATRA) vs. SPDR S&P 500 ETF (SPY)

Atara Biotherapeutics Business Overview & Revenue Model

Company DescriptionAtara Biotherapeutics, Inc., an off-the-shelf T-cell immunotherapy company, develops treatments for patients with cancer, autoimmune, and viral diseases in the United States. It is developing tabelecleucel, a T-cell immunotherapy that is Phase 3 clinical trials for the treatment of epstein-barr virus (EBV) driven post-transplant lymphoproliferative disease, as well as hematologic and solid tumors, including nasopharyngeal carcinoma. The company is also developing next-generation CAR T immunotherapies for patients with hematologic malignancies and solid tumors, including ATA2271 and ATA3271 for mesothelin; and ATA2431 and ATA3219 for B-cell malignancies, as well as ATA188 for the treatment of multiple sclerosis. In addition, it develops ATA368 program for patients with human papillomavirus associated cancers. Atara Biotherapeutics, Inc. has a license agreement with Memorial Sloan Kettering Cancer Center; license, and research and development collaboration agreement with QIMR Berghofer Medical Research Institute; and strategic collaboration with H. Lee Moffitt Cancer Center, as well as Bayer AG for mesothelin-targeted CAR T-cell therapies for solid tumors. The company was incorporated in 2012 and is headquartered in South San Francisco, California.
How the Company Makes MoneyAtara Biotherapeutics has historically generated revenue primarily from collaboration and licensing arrangements rather than from large-scale product sales, reflecting its clinical-stage profile. Key revenue streams typically include (1) collaboration/partner revenue such as upfront payments, development and regulatory milestones, and potential commercial milestones tied to progress and commercialization by a partner; and (2) reimbursement of research and development services performed under collaboration agreements (often recognized as collaboration revenue depending on contract structure and accounting treatment). Royalty income can be a potential future stream if partnered products reach commercialization and Atara retains royalty rights, but specific royalty rates and timing depend on the terms of each agreement. If Atara commercializes any therapy itself, future revenues could also include product sales (and potentially manufacturing-related revenue), but commercial-scale product revenue is not consistently available while products remain in development or pending approval. Significant factors influencing earnings include the pace and outcomes of clinical trials, regulatory decisions, the structure and performance of partnerships (including whether milestones are achieved), and the company’s ability to fund development—often through equity financings and other capital-raising activities, which provide cash but are not operating revenue. Specific current partnership terms and the exact composition of recent-period revenue are null.

Atara Biotherapeutics Financial Statement Overview

Summary
Despite a 2025 swing to reported profitability and reduced debt, the overall financial profile remains high risk due to persistently negative free cash flow (continued cash burn) and negative shareholder equity, alongside a volatile and declining revenue base.
Income Statement
34
Negative
Results show a sharp turnaround in profitability in 2025 (annual): net income improved to about $32.7M versus a large loss in 2024, with strong gross margin (low-80% range). However, revenue declined ~21% in 2025 after growing in 2024, indicating an unstable top line. Longer-term history (2021–2023) reflects very large losses and highly volatile margins, underscoring that profitability may not be durable.
Balance Sheet
18
Very Negative
The balance sheet is strained by persistently negative shareholder equity in 2023–2025, which is a major red flag for financial flexibility and capitalization quality. Debt is relatively low in 2025 (~$9.3M) and has come down meaningfully from prior years, but negative equity makes leverage ratios less informative and highlights that the company has been funding itself through losses and balance-sheet erosion. Total assets also declined sharply from earlier periods, suggesting a shrinking capital base.
Cash Flow
12
Very Negative
Cash generation remains weak: operating cash flow and free cash flow were materially negative in each year shown, including about -$50.9M in 2025. Cash burn improved versus 2024 and dramatically versus 2022–2023, but the business is still not self-funding. The gap between reported profitability (2025 net income positive) and continued cash outflow raises concerns about earnings quality and near-term funding needs.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue120.77M128.94M8.57M63.57M20.34M
Gross Profit99.56M107.93M-313.00K63.57M-261.66M
EBITDA35.86M-75.75M-266.00M-222.26M-331.12M
Net Income32.69M-85.40M-276.13M-228.30M-340.14M
Balance Sheet
Total Assets20.23M109.10M165.50M376.42M468.13M
Cash, Cash Equivalents and Short-Term Investments8.48M42.50M51.73M242.82M371.07M
Total Debt9.35M43.83M57.87M71.70M28.27M
Total Liabilities58.74M206.38M264.74M249.78M188.51M
Stockholders Equity-38.50M-97.28M-99.23M126.64M279.61M
Cash Flow
Free Cash Flow-50.94M-68.96M-194.20M-274.62M-231.10M
Operating Cash Flow-50.94M-68.72M-192.98M-270.43M-220.52M
Investing Cash Flow18.15M8.62M123.87M202.96M22.26M
Financing Cash Flow16.10M59.28M2.01M53.08M103.94M

Atara Biotherapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price15.79
Price Trends
50DMA
6.38
Negative
100DMA
10.64
Negative
200DMA
10.97
Negative
Market Momentum
MACD
0.04
Negative
RSI
50.01
Neutral
STOCH
66.31
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ATRA, the sentiment is Negative. The current price of 15.79 is above the 20-day moving average (MA) of 5.29, above the 50-day MA of 6.38, and above the 200-day MA of 10.97, indicating a neutral trend. The MACD of 0.04 indicates Negative momentum. The RSI at 50.01 is Neutral, neither overbought nor oversold. The STOCH value of 66.31 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ATRA.

Atara Biotherapeutics Risk Analysis

Atara Biotherapeutics disclosed 68 risk factors in its most recent earnings report. Atara Biotherapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Atara Biotherapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$195.80M-1.02-49.18%-33.76%17.54%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$218.57M-0.39-63.96%-28.50%
49
Neutral
$60.32M-1.41-71.28%-10.03%11.06%
43
Neutral
$197.02M-1.36-81.13%-9.70%23.23%
42
Neutral
$42.32M-11.29-41.78%51.27%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ATRA
Atara Biotherapeutics
5.87
-1.30
-18.13%
MGNX
MacroGenics
3.10
0.92
42.20%
ZNTL
Zentalis Pharmaceuticals
2.71
0.82
43.39%
SRZN
Surrozen
25.50
13.90
119.83%
TCRX
TScan Therapeutics
1.06
-0.49
-31.61%

Atara Biotherapeutics Corporate Events

Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Atara Plans FDA Type A Meeting on EBVALLO
Neutral
Mar 12, 2026

On March 12, 2026, Atara Biotherapeutics announced that it has scheduled a Type A meeting with the U.S. Food and Drug Administration to discuss the Complete Response Letter issued on January 9, 2026, for the Biologics License Application of its product EBVALLO. The scheduled meeting marks a key regulatory step for Atara as it works to address the FDA’s concerns and determine a potential path forward for tabelecleucel’s approval in the U.S. market.

The most recent analyst rating on (ATRA) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on Atara Biotherapeutics stock, see the ATRA Stock Forecast page.

Product-Related AnnouncementsRegulatory Filings and Compliance
Atara, Pierre Fabre seek FDA meeting on EBVALLO
Negative
Mar 3, 2026

On March 3, 2026, Atara Biotherapeutics reported that its partner Pierre Fabre Pharmaceuticals has requested a Type A meeting with the U.S. Food and Drug Administration to address issues raised in the Complete Response Letter issued on January 9, 2026, for the Biologics License Application for EBVALLO (tabelecleucel). The partners have submitted a briefing package arguing that the ALLELE study was adequate and well-controlled, supplemented by updated longer-term efficacy data, additional development data, and European post-marketing experience, underscoring the urgent need for tabelecleucel in patients with ultra-rare EBV-positive post-transplant lymphoproliferative disease and the potential path to revive U.S. approval prospects.

The most recent analyst rating on (ATRA) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on Atara Biotherapeutics stock, see the ATRA Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Atara Biotherapeutics Extends Royalty Milestone, Issues Warrant
Positive
Feb 23, 2026

On February 20, 2026, Atara Biotherapeutics amended its existing Purchase and Sale Agreement with a fund managed by HealthCare Royalty, pushing back a one-time $9.0 million milestone payment tied to its Pierre Fabre commercialization deal from June 30, 2026 to January 1, 2028. The revised timing eases near-term cash obligations as Atara and its partner work through U.S. regulatory issues for tabelecleucel while continuing to serve patients in Europe.

In exchange for the extension, Atara issued HCRx a warrant to purchase up to 400,000 shares of its common stock at a nominal exercise price of $0.0001 per share, exercisable immediately with no expiration but subject to a 4.99% beneficial ownership cap and cashless exercise provisions. The warrant, issued under a private placement exemption, underscores HCRx’s ongoing support and gives the royalty fund equity-linked upside as Atara pursues a potential U.S. approval path for tabelecleucel and seeks to strengthen its financial flexibility.

The most recent analyst rating on (ATRA) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on Atara Biotherapeutics stock, see the ATRA Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresProduct-Related AnnouncementsRegulatory Filings and Compliance
FDA Rejects Atara’s EBVALLO BLA, Commercial Path Uncertain
Negative
Jan 12, 2026

On January 12, 2026, Atara Biotherapeutics reported that the U.S. Food and Drug Administration issued a Complete Response Letter for EBVALLO (tabelecleucel), rejecting its Biologics License Application as a monotherapy for EBV-positive post-transplant lymphoproliferative disease in adults and children, despite previously resolving manufacturing compliance issues and raising no new safety concerns. The FDA, reversing its earlier stance, now deems the single-arm ALLELE trial inadequate to demonstrate effectiveness for accelerated approval, prompting Atara’s U.S. commercialization partner Pierre Fabre to seek a Type A meeting as the companies work to salvage a path forward for the therapy, while Atara continues a deep restructuring marked by a roughly 90% headcount reduction in 2025, amended commercialization milestones, a significant lease downsizing, and year-end 2025 cash, cash equivalents and short-term investments of about $8.5 million, subject to audit.

The most recent analyst rating on (ATRA) stock is a Hold with a $18.00 price target. To see the full list of analyst forecasts on Atara Biotherapeutics stock, see the ATRA Stock Forecast page.

Business Operations and Strategy
Atara revises tab-cel commercialization milestones with Pierre Fabre
Neutral
Jan 2, 2026

On December 30, 2025, Atara Biotherapeutics amended its commercialization agreement with Pierre Fabre Medicament, reducing potential regulatory milestone payments tied to FDA approval of a BLA for tab-cel from $40 million to $31 million in exchange for the opportunity to earn an additional $15 million milestone based on achieving a specified commercial milestone. The revised structure adjusts the balance between regulatory and commercial incentives, potentially aligning Pierre Fabre’s financial commitments more closely with tab-cel’s market performance and affecting the timing and composition of future milestone revenues for Atara.

The most recent analyst rating on (ATRA) stock is a Buy with a $25.00 price target. To see the full list of analyst forecasts on Atara Biotherapeutics stock, see the ATRA Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 17, 2026