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Alpha Cognition Inc (ACOG)
NASDAQ:ACOG
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Alpha Cognition Inc (ACOG) AI Stock Analysis

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ACOG

Alpha Cognition Inc

(NASDAQ:ACOG)

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Underperform 38 (OpenAI - 4o)
Rating:38Underperform
Price Target:
Alpha Cognition Inc. faces significant financial challenges with no revenue and increasing losses, heavily relying on external funding. While technical indicators are mixed, the recent earnings call provided a positive outlook with strategic initiatives in place. However, the negative valuation metrics and high operational risks weigh heavily on the stock's overall assessment.
Positive Factors
Strong Cash Position
A strong cash position provides Alpha Cognition with the financial flexibility to support ongoing R&D and commercialization efforts, crucial for a biotech firm in the development stage.
Intellectual Property Expansion
Extending patent protection enhances Alpha Cognition's competitive advantage, ensuring market exclusivity and potentially higher future revenue streams.
Strategic Partnerships
Partnerships with established firms like CMS Pharmaceuticals can accelerate market entry and expand geographical reach, crucial for long-term growth and revenue diversification.
Negative Factors
No Revenue Generation
The absence of revenue highlights the company's reliance on external funding and underscores the risk associated with its unproven commercial strategy.
Increasing Operating Losses
Rising operating losses indicate growing financial pressure, which could strain resources and delay reaching profitability, impacting long-term viability.
High Cash Burn Rate
A high cash burn rate necessitates continuous external funding, posing a risk to sustainability if capital markets become less favorable.

Alpha Cognition Inc (ACOG) vs. SPDR S&P 500 ETF (SPY)

Alpha Cognition Inc Business Overview & Revenue Model

Company DescriptionAlpha Cognition Inc., a clinical stage biopharmaceutical company, engages in the development of treatments for Alzheimer's disease and amyotrophic lateral sclerosis (ALS). The company offers ZUNVEYL (benzgalantamine) for the treatment of mild-to-moderate Alzheimer's disease and mild traumatic brain injury. It also develops ALPHA-0602, a gene therapy for the treatment of ALS; and ALPHA-0702 and ALPHA-0802, a granulin epithelin motifs for the treatment of neurodegenerative diseases. The company was formerly known as Crystal Bridge Enterprises Inc. and changed its name to Alpha Cognition Inc. in March 2021. Alpha Cognition Inc. was founded in 2000 and is headquartered in Vancouver, Canada.
How the Company Makes MoneyAlpha Cognition Inc generates revenue through the development and commercialization of its therapeutic products. The company primarily makes money by advancing its drug candidates through clinical trials and eventually bringing them to market, either independently or through strategic partnerships and collaborations with larger pharmaceutical companies. These partnerships may involve licensing agreements, where Alpha Cognition receives upfront payments, milestone payments based on the achievement of certain development and regulatory goals, and royalties on future sales of the approved products. Additionally, the company may also receive funding from grants or research collaborations aimed at fostering innovation in the neurodegenerative disease space. The successful commercialization of its drug candidates is crucial to the company's revenue generation and growth.

Alpha Cognition Inc Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Apr 07, 2026
Earnings Call Sentiment Positive
The earnings call reflected a strong positive momentum with significant growth in ZUNVEYL sales and market engagement, supported by a solid financial position. However, challenges such as operating losses and limited payer coverage remain.
Q3-2025 Updates
Positive Updates
Sales Growth of ZUNVEYL
The third quarter of 2025 saw a significant increase in sales for ZUNVEYL, with ex-factory purchases rising 44% quarter-over-quarter and demand sales bottles dispensed growing by 102% from Q2.
Successful Engagement in Long-Term Care Market
Alpha Cognition engaged 2,038 homes in Q3, bringing the total reach to 2,942 unique homes, with 70% of those homes placing repeat orders.
Positive Clinical Feedback
ZUNVEYL has shown good clinical performance with reports of cognition improvement and limited adverse events, maintaining a low single-digit rate of GI adverse events.
Strong Financial Position
The company raised $38 million in net proceeds through an equity offering, extending their operational runway into 2027.
Progress in Research and Development
Alpha Cognition plans to initiate two studies, CONVERGE and BEACON, to assess ZUNVEYL's cognitive benefits and tolerability, with completion expected in late 2026.
Negative Updates
Operating Loss
The company reported an operating loss of $5.3 million for the quarter, an increase from the $2.5 million loss in the same period last year, due to higher SG&A costs.
Challenges with Payer Coverage
Only 15% of business lines have covered ZUNVEYL without restriction, and there are ongoing challenges in navigating payer obstacles and securing broader coverage.
High Operating Expenses
Total operating expenses increased to $8.2 million, reflecting higher costs associated with commercial launch activities.
Company Guidance
During the third quarter of 2025, Alpha Cognition reported significant progress with their Alzheimer's treatment, ZUNVEYL. Sales of ZUNVEYL experienced robust growth, with ex-factory purchases increasing by 44% from 2,640 to 3,808 bottles compared to the previous quarter, and demand sales bottles dispensed growing by 102%. The company engaged with over 1,850 prescribers, leading to prescriptions being written in over 500 nursing homes, with 70% of these homes seeing repeat prescriptions. Total revenue for the quarter was $2.8 million, comprised of $2.3 million from net product sales and $507,000 from licensing revenue. Despite an operating loss of $5.3 million, improvements in fair value of derivative liabilities and interest income helped reduce the net loss to $1.3 million. The company also managed to raise $38 million in October, strengthening their balance sheet and extending their operational runway into 2027. Looking ahead, Alpha Cognition expects continued growth in ZUNVEYL sales as they expand market access, and they anticipate full-year operating expenses for 2025 to be between $28 million and $30 million, a decrease from prior guidance due to cost discipline and operational efficiency.

Alpha Cognition Inc Financial Statement Overview

Summary
Alpha Cognition Inc.'s financials depict a company in a typical biotechnology development stage, with no revenue and significant cash consumption for operations. The financial health relies heavily on external financing, raising concerns about sustainability and the need for successful product commercialization. While the cash position is strong due to recent financing, the lack of revenue and increasing losses highlight significant risks.
Income Statement
10
Very Negative
Alpha Cognition Inc. has consistently reported no revenue over the past five years, indicating a lack of commercialized products or services. The net losses have widened over time, with a significant negative EBIT and EBITDA, reflecting high operating expenses relative to non-existent revenue. This suggests substantial financial pressure and highlights the company's reliance on external funding to support its operations.
Balance Sheet
20
Very Negative
The company shows a strong cash position with cash and short-term investments significantly exceeding total debt, leading to a negative net debt. However, the equity position has fluctuated, with negative stockholders' equity in some years, indicating potential liquidity concerns and financial instability. The low debt-to-equity ratio in recent years is positive but primarily due to negative equity, which is not favorable for long-term financial health.
Cash Flow
25
Negative
Operating cash flows are negative, reflecting ongoing losses and cash burn typical of biotechnology firms in early stages. However, the company has managed to raise substantial financing, improving its cash position. The absence of positive free cash flow growth underscores the challenges in achieving operational sustainability without continued external funding.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue7.43M0.000.000.000.000.00
Gross Profit5.43M0.000.000.000.000.00
EBITDA-18.62M-14.37M-13.62M-11.85M-18.93M-4.93M
Net Income-19.47M-14.64M-13.77M-12.11M-19.55M-5.78M
Balance Sheet
Total Assets46.30M50.74M2.45M2.95M12.88M8.44M
Cash, Cash Equivalents and Short-Term Investments35.40M48.55M1.49M2.08M11.30M5.93M
Total Debt0.00911.46K1.22M1.21M1.08M3.22M
Total Liabilities12.39M9.27M7.16M4.27M3.85M8.42M
Stockholders Equity33.91M41.46M-4.71M-1.32M9.03M16.01K
Cash Flow
Free Cash Flow-15.98M-7.78M-8.73M-9.25M-9.94M-5.45M
Operating Cash Flow-15.83M-7.76M-8.73M-9.24M-9.88M-5.44M
Investing Cash Flow-173.58K-26.70K0.00-4.88K459.38K-9.24K
Financing Cash Flow47.66M54.85M8.16M24.79K14.88M5.88M

Alpha Cognition Inc Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5.81
Price Trends
50DMA
6.60
Negative
100DMA
7.84
Negative
200DMA
7.47
Negative
Market Momentum
MACD
-0.23
Negative
RSI
39.32
Neutral
STOCH
24.26
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ACOG, the sentiment is Negative. The current price of 5.81 is below the 20-day moving average (MA) of 5.94, below the 50-day MA of 6.60, and below the 200-day MA of 7.47, indicating a bearish trend. The MACD of -0.23 indicates Negative momentum. The RSI at 39.32 is Neutral, neither overbought nor oversold. The STOCH value of 24.26 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ACOG.

Alpha Cognition Inc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$153.95M-158.88%-16.26%
45
Neutral
$148.12M-480.02%-37.13%40.47%
44
Neutral
$139.06M-331.24%5.01%20.76%
41
Neutral
$138.51M-2.39-109.73%50.39%
38
Underperform
$124.36M-125.65%52.52%
30
Underperform
$149.50M-2.1917.36%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ACOG
Alpha Cognition Inc
5.81
0.07
1.22%
SGMO
Sangamo Biosciences
0.50
-1.44
-74.28%
ELTX
Elicio Therapeutics
8.05
2.99
59.09%
CGTX
Cognition Therapeutics
1.80
1.42
373.68%
LUCD
Lucid Diagnostics
1.04
0.16
18.18%
NVCT
Nuvectis Pharma
6.38
1.56
32.37%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 30, 2025