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Absci Corp. (ABSI)
NASDAQ:ABSI
US Market
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AbSci (ABSI) AI Stock Analysis

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ABSI

AbSci

(NASDAQ:ABSI)

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Neutral 56 (OpenAI - 5.2)
Rating:56Neutral
Price Target:
$5.50
▲(53.63% Upside)
Action:Reiterated
Date:05/10/26
ABSI’s score is held back primarily by weak financial performance (deep losses, shrinking revenue, and substantial cash burn), partially offset by a strong low-debt balance sheet and a generally positive earnings-call outlook with clear clinical catalysts and stated runway. Technicals are supportive but appear overbought, and valuation is constrained by ongoing losses and no dividend support.
Positive Factors
Low leverage balance sheet
Very low debt reduces refinancing and solvency risk, giving management durable financial flexibility to fund R&D or pursue partnerships over the next 2–6 months. This balance-sheet strength supports execution of clinical catalysts without immediate creditors pressuring near-term decisions.
Negative Factors
Shrinking revenue and deep losses
Declining, negligible revenue paired with large net losses signals weak near-term commercial traction for services and limited internal revenue to fund R&D. Structurally, this increases reliance on external financing or partnerships and constrains reinvestment flexibility across the next several quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Low leverage balance sheet
Very low debt reduces refinancing and solvency risk, giving management durable financial flexibility to fund R&D or pursue partnerships over the next 2–6 months. This balance-sheet strength supports execution of clinical catalysts without immediate creditors pressuring near-term decisions.
Read all positive factors

AbSci (ABSI) vs. SPDR S&P 500 ETF (SPY)

AbSci Business Overview & Revenue Model

Company Description
Absci Corporation, a drug and target discovery company, provides biologic drug candidates and production cell lines using integrated drug creation platform for partners in the United States. Its integrated drug creation platform enables the creati...
How the Company Makes Money
AbSci primarily makes money by providing drug discovery and development services to biopharmaceutical partners under collaboration agreements. Revenue is generally generated through (a) research and development service fees for conducting discover...

AbSci Earnings Call Summary

Earnings Call Date:May 07, 2026
(Q1-2026)
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% Change Since: |
Next Earnings Date:Aug 18, 2026
Earnings Call Sentiment Positive
The call conveyed clear progress on the lead program (ABS-201) with favorable early safety/PK signals, supportive PK modeling for an infrequent dosing profile, a defined clinical timeline (interim 13-week readout in H2 2026 and full 26-week POC in early 2027), and a substantial addressable market supported by consumer and KOL research. The company expanded its prolactin-focused pipeline (ABS-202), sharpened strategic focus by de‑emphasizing oncology, and reported a cash runway into H1 2028. Offsetting these positives are a very small quarter revenue base ($200k), a cash decline of ~12.9% QoQ to $125.7M, increased R&D spend (+17.7% YoY), and remaining clinical and regulatory risks (directional 13-week readout, placebo risk in endometriosis). Overall, the call emphasized promising clinical and commercial potential but also highlighted near-term execution and financing sensitivities.
Positive Updates
ABS-201 HEADLINE Trial Progressing On Track
Phase I/IIa HEADLINE trial tracking to plan: all 4 single ascending dose (SAD) cohorts dosed and first multiple ascending dose (MAD) cohort initiated. Emerging safety and tolerability data described as favorable, with blinded preliminary safety, tolerability and PK data expected next month. Interim 13-week directional hair regrowth readout planned for H2 2026 and full 26-week proof-of-concept (POC) readout expected early 2027.
Negative Updates
Minimal Near-Term Revenue
Revenue for the quarter was only $200,000, indicating limited near-term partnered revenue generation and continuing reliance on capital markets / partnerships for non-dilutive funding.
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Q1-2026 Updates
Negative
ABS-201 HEADLINE Trial Progressing On Track
Phase I/IIa HEADLINE trial tracking to plan: all 4 single ascending dose (SAD) cohorts dosed and first multiple ascending dose (MAD) cohort initiated. Emerging safety and tolerability data described as favorable, with blinded preliminary safety, tolerability and PK data expected next month. Interim 13-week directional hair regrowth readout planned for H2 2026 and full 26-week proof-of-concept (POC) readout expected early 2027.
Read all positive updates
Company Guidance
Management provided a data‑rich roadmap: blinded preliminary safety, tolerability and PK data from the completed 4 SAD cohorts (with the first MAD cohort now dosing) will be shared next month, an interim 13‑week directional proof‑of‑concept hair‑regrowth readout is expected in H2 2026 and the full 26‑week POC readout in early 2027, with planned initiation of a Phase II endometriosis trial in Q4 2026 (subject to data/regulatory review) and the potential to advance directly to registrational trials; preliminary PK modeling supports a targeted dosing interval of 2–3 injections over 6 months (at least ~every 8 weeks) and a ~90% receptor‑occupancy goal. Market research tested a target product profile of 3 injections yielding ~35 hairs/cm2 and ~2.5 years of durability, supporting a U.S. AGA TAM >$25B and potential peak endometriosis sales >$4B (endometriosis prevalence up to 10% of women worldwide, ~9M in the U.S.), while consumer intent in surveys was high (87% of men, 69% of women overall; rising to 92%/89% among those already on standard‑of‑care). Financially, Q1 revenue was $200K, R&D expense $19.3M (vs $16.4M prior year), SG&A $9.1M (vs $9.5M), and cash, cash equivalents and marketable securities were $125.7M (down from $144.3M at 12/31/25), which management expects is sufficient to fund operations into the first half of 2028; strategic moves include adding ABS‑202, deprioritizing oncology programs ABS‑301/ABS‑501, pursuing partnerships and realizing efficiency gains from agentic AI.

AbSci Financial Statement Overview

Summary
Financials show an early-stage biotech mix: a strong, low-leverage balance sheet (debt-to-equity ~0.03) but very weak operating performance. Revenue is very small and declining (TTM $1.6M, ~-42% vs prior), profitability is deeply negative (TTM net income -$118.4M), and cash burn remains heavy (TTM FCF -$98.5M), despite modest year-over-year improvement.
Income Statement
18
Very Negative
Balance Sheet
72
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue1.84M2.80M4.53M5.72M5.75M4.78M
Gross Profit-24.18M-8.94M-57.92M-41.85M-53.16M-39.80M
EBITDA-115.54M-112.98M-94.10M-79.68M-93.71M-67.68M
Net Income-118.44M-115.18M-103.11M-110.57M-104.90M-100.96M
Balance Sheet
Total Assets195.59M216.30M213.61M217.30M321.01M426.19M
Cash, Cash Equivalents and Short-Term Investments125.70M144.29M112.42M97.66M164.43M252.57M
Total Debt4.42M5.30M10.11M15.88M22.98M20.01M
Total Liabilities23.62M26.85M34.48M41.12M46.59M60.09M
Stockholders Equity171.97M189.45M179.13M176.18M274.41M366.11M
Cash Flow
Free Cash Flow-98.50M-94.03M-72.81M-65.50M-97.51M-98.64M
Operating Cash Flow-97.39M-92.92M-72.40M-64.64M-81.34M-60.60M
Investing Cash Flow-27.75M-50.16M-41.58M81.94M-126.98M-67.38M
Financing Cash Flow70.71M105.95M82.53M-4.48M5.24M336.19M

AbSci Technical Analysis

Technical Analysis Sentiment
Positive
Last Price3.58
Price Trends
50DMA
3.97
Positive
100DMA
3.45
Positive
200DMA
3.36
Positive
Market Momentum
MACD
0.30
Positive
RSI
55.90
Neutral
STOCH
29.59
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ABSI, the sentiment is Positive. The current price of 3.58 is below the 20-day moving average (MA) of 5.25, below the 50-day MA of 3.97, and above the 200-day MA of 3.36, indicating a neutral trend. The MACD of 0.30 indicates Positive momentum. The RSI at 55.90 is Neutral, neither overbought nor oversold. The STOCH value of 29.59 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ABSI.

AbSci Risk Analysis

AbSci disclosed 91 risk factors in its most recent earnings report. AbSci reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

AbSci Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
$685.15M-9.27-33.07%-20.34%
57
Neutral
$452.46M-1.28-128.53%928.46%-21.39%
56
Neutral
$795.12M-3.88-63.58%-61.87%10.39%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$449.58M-2.30-36.83%383560.87%20.87%
44
Neutral
$431.18M-4.3865.27%4.43%27.41%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ABSI
AbSci
5.10
2.38
87.50%
AUTL
Autolus Therapeutics
1.70
0.16
10.39%
ADCT
ADC Therapeutics
3.39
0.89
35.60%
FDMT
4D Molecular Therapeutics
8.60
5.18
151.46%
DSGN
Design Therapeutics
10.97
7.09
182.73%

AbSci Corporate Events

Business Operations and StrategyFinancial Disclosures
Absci Advances ABS-201 Hair Loss Trial Amid Wider Loss
Neutral
May 7, 2026
Absci reported first-quarter 2026 results on May 7, 2026, highlighting progress on its AI-designed prolactin receptor pipeline and a widening operating loss as RD spending increased. Revenue for the quarter fell to $0.2 million from $1.2 million a...
Business Operations and StrategyExecutive/Board ChangesFinancial Disclosures
Absci Reports 2025 Results and Advances ABS-201 Program
Positive
Mar 24, 2026
On March 24, 2026, Absci reported fourth quarter and full-year 2025 results, highlighting clinical progress on ABS-201, its anti-PRLR antibody for androgenetic alopecia and endometriosis, including successful dosing of the first three cohorts in t...
Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and Compliance
Absci Updates Leadership Indemnification Agreements Amid Governance Focus
Positive
Mar 6, 2026
On March 6, 2026, Absci’s board approved amended and restated indemnification agreements for its directors and officers under Delaware law, refining change-of-control definitions, extending coverage for separate counsel in such events, and a...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 10, 2026