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Spyre Therapeutics (SYRE)
NASDAQ:SYRE
SYRE Analyst Ratings
Strong Buy
7 Buy
0 Hold
0 Sell
TipRanks enables you to focus on the analyst rating consensus of all analysts or only the top performers in the past 3 months
SYRE Stock 12 Month Forecast
Average Price Target
$57.17
▲(70.81% Upside)
| Highest Price Target$70.00 | Average Price Target$57.17 | Lowest Price Target$43.00 |
The highest, average, and lowest price target of all analysts. Click on ‘Top Analysts’ to focus on the best performers.
Detailed List of Analyst Forecasts
Detailed List of Analyst Forecasts
Mizuho Securities
$53
Buy
58.35%
Upside
Initiated
12/18/25
Citi
$64
Buy
91.22%
Upside
Initiated
12/17/25
LifeSci Capital
$49
Buy
46.40%
Upside
Reiterated
12/04/25
JonesTrading
$64
Buy
91.22%
Upside
Upgraded
12/01/25
BTIG
$70
Buy
109.14%
Upside
Reiterated
11/04/25
TD Cowen
Buy
―
Reiterated
11/04/25
Deutsche Bank
$43
Buy
28.47%
Upside
Initiated
09/26/25
Leerink Partners
Buy
―
Reiterated
09/11/25
Stifel Nicolaus
$17.18→$71
Buy
112.13%
Upside
Reiterated
06/23/25
Wells Fargo
$40
Buy
19.51%
Upside
Reiterated
06/18/25
Evercore ISI
Buy
―
Reiterated
06/18/25
Wedbush
$65
Buy
94.20%
Upside
Reiterated
06/17/25
Wolfe Research
$27
Buy
-19.33%
Downside
Initiated
03/17/25
Analyst Type
Any
Ranks
Any
Analyst Rating
Any
Upside/ Downside
Any
Action
Any
Mizuho Securities
$53
Buy
58.35%
Upside
Initiated
12/18/25
Citi
$64
Buy
91.22%
Upside
Initiated
12/17/25
LifeSci Capital
$49
Buy
46.40%
Upside
Reiterated
12/04/25
JonesTrading
$64
Buy
91.22%
Upside
Upgraded
12/01/25
BTIG
$70
Buy
109.14%
Upside
Reiterated
11/04/25
TD Cowen
Buy
―
Reiterated
11/04/25
Deutsche Bank
$43
Buy
28.47%
Upside
Initiated
09/26/25
Leerink Partners
Buy
―
Reiterated
09/11/25
Stifel Nicolaus
$17.18→$71
Buy
112.13%
Upside
Reiterated
06/23/25
Wells Fargo
$40
Buy
19.51%
Upside
Reiterated
06/18/25
Evercore ISI
Buy
―
Reiterated
06/18/25
Wedbush
$65
Buy
94.20%
Upside
Reiterated
06/17/25
Wolfe Research
$27
Buy
-19.33%
Downside
Initiated
03/17/25
Best Analysts Covering Spyre Therapeutics
1 Month
xxx
Success Rate
8/11 ratings generated profit
Average Return
+15.44%
reiterated a xxx
rating 2 months ago
Copying xxxxxxxxxxxxxxxxxx
trades and holding each position for 1 Month would result in 72.73% of your transactions generating a profit, with an average return of +15.44% per trade.
3 Months
xxx
Success Rate
7/11 ratings generated profit
Average Return
+24.48%
reiterated a xxx
rating 6 months ago
Copying xxxxxxxxxxxxxxxxxx
trades and holding each position for 3 Months would result in 63.64% of your transactions generating a profit, with an average return of +24.48% per trade.
1 Year
Success Rate
9/11 ratings generated profit
Average Return
+64.23%
reiterated a buy rating 6 months ago
Copying Alex Thompson CFA's trades and holding each position for 1 Year would result in 81.82% of your transactions generating a profit, with an average return of +64.23% per trade.
2 Years
xxx
Success Rate
11/11 ratings generated profit
Average Return
+57.45%
reiterated a xxx
rating 6 months ago
Copying xxxxxxxxxxxxxxxxxx
trades and holding each position for 2 Years would result in 100.00% of your transactions generating a profit, with an average return of +57.45% per trade.
The Best Analyst Covering tool allows you to follow the analysts who have the best success rates and average returns on a specific stock. Only analysts that gave a Buy or Sell rating on the stock in the past 12 months are eligible for inclusion in this tool. Follow the analysts of your choice to receive real-time updates when they publish a new rating.
SYRE Analyst Recommendation Trends
Rating
Jul 25
Aug 25
Sep 25
Nov 25
Dec 25
Strong Buy
14
11
7
8
8
Buy
4
6
5
5
3
Hold
2
2
2
2
1
Sell
0
0
0
0
0
Strong Sell
0
0
0
0
0
total
20
19
14
15
12
Each month's total comprises the sum of three months' worth of ratings.
SYRE Financial Forecast
SYRE Stock Forecast FAQ
What is SYRE’s average 12-month price target, according to analysts?
Based on analyst ratings, Spyre Therapeutics’s 12-month average price target is 57.17.
What is SYRE’s upside potential, based on the analysts’ average price target?
Spyre Therapeutics has 70.81% upside potential, based on the analysts’ average price target.
Can I see which stocks the top-ranking analysts are rating?
Yes, go to the Analysts’ Top Stocks tool to see stocks with a Strong Buy or Strong Sell analyst rating consensus, according to the top performers.
How can I follow the stock ratings of top Wall Street analysts?
Head over to our Expert Center to see a list of the top 100 Wall Street analysts and follow the analysts of your choice. Visit their profiles for more details about their stock ratings and see how they perform on a stock-by-stock basis.
Is SYRE a Buy, Sell or Hold?
Spyre Therapeutics has a consensus rating of Strong Buy which is based on 7 buy ratings, 0 hold ratings and 0 sell ratings.
What is Spyre Therapeutics’s price target?
The average price target for Spyre Therapeutics is 57.17. This is based on 7 Wall Streets Analysts 12-month price targets, issued in the past 3 months.
The highest analyst price target is $70.00 ,the lowest forecast is $43.00. The average price target represents 70.81% Increase from the current price of $33.47.
The highest analyst price target is $70.00 ,the lowest forecast is $43.00. The average price target represents 70.81% Increase from the current price of $33.47.
What do analysts say about Spyre Therapeutics?
Spyre Therapeutics’s analyst rating consensus is a Strong Buy. This is based on the ratings of 7 Wall Streets Analysts.
How can I buy shares of SYRE?
Open a brokerage account, see exclusive account opening deals on our Best Online Brokers page.