Biomarker‑driven ExpansionA focused Cyclin E1 biomarker strategy plus planned mechanism‑based combinations offers a credible route to broaden azenosertib's use into additional tumor types and treatment settings.
Clinical DifferentiationReproducible efficacy versus standard chemotherapy positions azenosertib as a potentially differentiated therapy in Cyclin E1‑driven ovarian cancer, which could drive investor interest on positive data.
Enrollment MilestoneCompletion of enrollment in DENALI Part 2a provides a clear path to a pivotal efficacy readout for azenosertib in Cyclin E1‑positive platinum‑resistant ovarian cancer, supporting upside if results meet expectations.