Clinical ProgressCompleted enrollment in Part 2a of the DENALI Phase 2 trial confirms the primary dose for azenosertib and advances the program toward a pivotal efficacy readout.
Pipeline ExpansionInitiation of mechanism‑driven combination studies, including pairing azenosertib with antibody‑drug conjugates, could broaden clinical applications and commercial potential across tumor types.
Regulatory PositioningAlignment with the FDA and a planned confirmatory Phase 3 trial positions azenosertib to pursue accelerated approval in Cyclin E1 positive platinum‑resistant ovarian cancer.