Efficacy And Market PotentialZentalis remains committed to developing azenosertib for cyclin E1-positive platinum-resistant ovarian cancer (PROC), where it has demonstrated promising clinical efficacy, with an ORR of approximately 35% in DENALI Part 1b, alongside a favorable safety profile.
Leadership And Strategic DirectionMultiple management changes add regulatory and commercial experience as company transitions to later stage development and potential commercialization.
Regulatory Pathway And Market PositionWith a clear regulatory pathway, a biomarker-driven strategy, and a significant market opportunity, Zentalis is well-positioned to deliver a transformative therapy for PROC patients.