Competitive LandscapeSeveral other competitors are further ahead in clinical development with their B7-H3-targeted ADCs.
Discontinued DevelopmentThe company has decided to discontinue further development based on the interim data, which failed to show an improvement in rPFS over the control arm for the target population.
Pending Clinical Trial ResultsThe fate of lorigerlimab hinges on the Phase II LORIKEET update, where a path forward may be feasible if an 8+ month rPFS is achieved.