Want to see SPRO full AI Analyst Report?
SPRO Stock Chart & Stats
$2.59
-$0.03(-2.91%)
At close: 4:00 PM EST
$2.59
-$0.03(-2.91%)
Day’s Range― - ―
52-Week Range$1.80 - $3.08
Previous CloseN/A
Volume61.58K
Average Volume (3M)1.40M
Market Cap
$122.75M
Enterprise Value$68.52M
Total Cash (Recent Filing)$56.13M
Total Debt (Recent Filing)$2.47M
Price to Earnings (P/E)7.8
Beta1.51
Next Earnings
Aug 12, 2026EPS EstimateN/A
Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)0.27
Shares Outstanding57,901,493
10 Day Avg. Volume612,810
30 Day Avg. Volume1,400,423
Financial Highlights & Ratios
PEG Ratio-0.14
Price to Book (P/B)2.21
Price to Sales (P/S)2.19
P/FCF Ratio-10.34
Enterprise Value/Market Cap0.56
Enterprise Value/Revenue1.25
Enterprise Value/Gross Profit1.25
Enterprise Value/Ebitda4.60
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)0.67
Revenue Forecast (FY)$800.00K
Bulls Say, Bears Say
Bulls Say
Clinical Trial SuccessAnalyst points out that the Phase 3 trial for tebipenem met its primary endpoint early and was stopped for efficacy, strengthening the case for a robust regulatory submission and improved commercial prospects.
Financial Runway And Cost ControlAnalyst observes that reduced research spending after trial completion, together with cash reserves expected to support operations into 2028, lowers near-term financing risk and enhances financial stability.
Partnership MilestonesAnalyst highlights that the licensing agreement with GSK includes multiple milestone payments and tiered royalties that could deliver significant non-dilutive revenue if regulatory and commercial triggers are achieved.
Bears Say
Milestone Payment ReductionAnalyst warns that early trial termination led to a prorated milestone payment materially below initial expectations, reducing anticipated near-term cash inflows from the GSK deal.
Operating LossesAnalyst notes a reported net loss that highlights ongoing operating deficits and raises the possibility of additional financing needs if anticipated partner payments or royalties are delayed.
Spero Therapeutics News
SPRO FAQ
What was Spero Therapeutics’s price range in the past 12 months?
Spero Therapeutics lowest stock price was $1.80 and its highest was $3.08 in the past 12 months.
What is Spero Therapeutics’s market cap?
Spero Therapeutics’s market cap is $122.75M.
When is Spero Therapeutics’s upcoming earnings report date?
Spero Therapeutics’s upcoming earnings report date is Aug 12, 2026 which is in 32 days.
How were Spero Therapeutics’s earnings last quarter?
Spero Therapeutics released its earnings results on May 13, 2026. The company reported -$0.13 earnings per share for the quarter, missing the consensus estimate of N/A by -$0.13.
Is Spero Therapeutics overvalued?
According to Wall Street analysts Spero Therapeutics’s price is currently Overvalued.
Does Spero Therapeutics pay dividends?
Spero Therapeutics pays a Quarterly dividend of $0.015 which represents an annual dividend yield of N/A. See more information on Spero Therapeutics dividends here
What is Spero Therapeutics’s EPS estimate?
Spero Therapeutics’s EPS estimate for its next earnings report is not yet available.
How many shares outstanding does Spero Therapeutics have?
Spero Therapeutics has 57,901,493 shares outstanding.
What happened to Spero Therapeutics’s price movement after its last earnings report?
Spero Therapeutics reported an EPS of -$0.13 in its last earnings report, missing expectations of N/A. Following the earnings report the stock price went up 13.115%.
Which hedge fund is a major shareholder of Spero Therapeutics?
Currently, no hedge funds are holding shares in SPRO
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Spero Therapeutics Stock Smart Score
Neutral
1
2
3
4
5
6
7
8
9
10
Blogger Sentiment
Neutral
SPRO Sentiment 50%
Sector Average 69%
Sector Average 69%
Hedge Fund Trend
Decreased
By 203.1K Shares
Last Quarter.
Last Quarter.
Insider Transactions
Sold Shares
Worth $63.4K over
the Last 3 Months
the Last 3 Months
Crowd Wisdom
Positive
Last 7 Days ▼ 1.2%
Last 30 Days ▲ 4.6%
Last 30 Days ▲ 4.6%
Technicals
SMA
Negative
20 days / 200 days
Momentum
-26.05%
12-Months-Change
Fundamentals
Return on Equity
35.58%
Trailing 12-Months
Asset Growth
-24.05%
Trailing 12-Months
Company Description
Spero Therapeutics
Spero Therapeutics, Inc. is a biopharmaceutical firm in the clinical development stage, primarily focused on discovering, advancing, and commercializing innovative treatments for multi-drug resistant (MDR) bacterial infections and rare diseases within the United States. The company's pipeline includes several key therapeutic candidates: tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-class antibiotic designed to address complicated urinary tract infections (cUTIs), including pyelonephritis, in adult patients. SPR206, an intravenously administered agent specifically developed to combat MDR Gram-negative bacterial infections in hospital environments. SPR720, an oral antibiotic targeting non-tuberculous mycobacterial (NTM) pulmonary disease. Spero Therapeutics has also forged several strategic alliances: A licensing agreement with Meiji Seika Pharma Co., Ltd. supports the ongoing development of tebipenem HBr. A separate licensing deal with Everest Medicines grants rights for the development, manufacturing, and commercialization of SPR206 across Greater China, South Korea, and various Southeast Asian nations. The company collaborates with the Bill & Melinda Gates Medical Research Institute to advance SPR720 for treating lung infections caused by Mycobacterium tuberculosis. Furthermore, a licensing agreement with Vertex Pharmaceuticals Incorporated covers patents associated with SPR720 and its active metabolite, SPR719. Founded in 2013, Spero Therapeutics maintains its corporate headquarters in Cambridge, Massachusetts.
Technical Analysis
Milestone Pharmaceuticals
―
Korro Bio
―
Connect Biopharma Holdings
―
Tenaya Therapeutics
―
Contineum Therapeutics, Inc. Class A
―
Ownership Overview
5.30% Insiders
4.06% Mutual Funds
0.07% Other Institutional Investors
86.93% Public Companies and
Individual Investors