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Spero Therapeutics Inc (SPRO)
NASDAQ:SPRO
SPRO Stock Chart & Stats
$2.50
-$0.03(-2.91%)
At close: 4:00 PM EST
$2.50
-$0.03(-2.91%)
Day’s Range― - ―
52-Week Range$0.51 - $3.22
Previous CloseN/A
Volume61.58K
Average Volume (3M)932.06K
Market Cap
$138.44M
Enterprise Value$134.90M
Total Cash (Recent Filing)$31.19M
Total Debt (Recent Filing)$3.62M
Price to Earnings (P/E)―
Beta1.63
Next Earnings
Nov 13, 2025EPS Estimate
-0.25Last Dividend Ex-Date
Sep 16, 2015Dividend YieldN/A
Share Statistics
EPS (TTM)-0.03
Shares Outstanding56,275,227
10 Day Avg. Volume499,157
30 Day Avg. Volume932,064
Financial Highlights & Ratios
PEG Ratio<0.01
Price to Book (P/B)1.21
Price to Sales (P/S)2.03
P/FCF Ratio-2.37
Enterprise Value/Market Cap0.97
Enterprise Value/Revenue3.33
Enterprise Value/Gross Profit3.33
Enterprise Value/Ebitda-2.39
Forecast
1Y Price Target
$4.00Price Target Upside60.00% Upside
Rating ConsensusHold
Number of Analyst Covering2
EPS Forecast (FY)-0.46
Revenue Forecast (FY)$20.10M
Bulls Say, Bears Say
Bulls Say
Clinical TrialsThe Phase 3 trial of tebipenem in cUTI met its primary endpoint and was stopped early for efficacy.
Financial MilestonesSPRO will receive up to $351 million in additional development, sales, and commercial milestones, along with royalties on net product sales.
Operational FundingCash reserves, along with milestone payments from GSK, should provide operational expense coverage into 2028.
Bears Say
Net LossSPRO reported a net loss of $1.7 million for the second quarter.
Reduced Milestone PaymentDue to the trial stopping early at ~64% of full enrollment, driving lower R&D costs, SPRO will now not receive the full $150M but a prorated amount closer to ~$96M.
Spero Therapeutics News
SPRO FAQ
What was Spero Therapeutics Inc’s price range in the past 12 months?
Spero Therapeutics Inc lowest stock price was $0.51 and its highest was $3.22 in the past 12 months.
What is Spero Therapeutics Inc’s market cap?
Spero Therapeutics Inc’s market cap is $138.44M.
When is Spero Therapeutics Inc’s upcoming earnings report date?
Spero Therapeutics Inc’s upcoming earnings report date is Nov 13, 2025 which is today.
How were Spero Therapeutics Inc’s earnings last quarter?
Spero Therapeutics Inc released its earnings results on Aug 12, 2025. The company reported -$0.03 earnings per share for the quarter, beating the consensus estimate of -$0.38 by $0.35.
Is Spero Therapeutics Inc overvalued?
According to Wall Street analysts Spero Therapeutics Inc’s price is currently Undervalued.
Does Spero Therapeutics Inc pay dividends?
Spero Therapeutics Inc pays a Quarterly dividend of $0.015 which represents an annual dividend yield of N/A. See more information on Spero Therapeutics Inc dividends here
What is Spero Therapeutics Inc’s EPS estimate?
Spero Therapeutics Inc’s EPS estimate is -0.25.
How many shares outstanding does Spero Therapeutics Inc have?
Spero Therapeutics Inc has 56,275,227 shares outstanding.
What happened to Spero Therapeutics Inc’s price movement after its last earnings report?
Spero Therapeutics Inc reported an EPS of -$0.03 in its last earnings report, beating expectations of -$0.38. Following the earnings report the stock price went down -17.797%.
Which hedge fund is a major shareholder of Spero Therapeutics Inc?
Currently, no hedge funds are holding shares in SPRO
Spero Therapeutics Stock Smart Score
Neutral
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10
Analyst Consensus
Hold
Average Price Target:
$4.00 (60.00% Upside)
$4.00 (60.00% Upside)
Blogger Sentiment
Bullish
SPRO Sentiment 100%
Sector Average ―
Sector Average ―
Hedge Fund Trend
Decreased
By 22.9K Shares
Last Quarter.
Last Quarter.
Insider Transactions
Sold Shares
Worth $16.3K over
the Last 3 Months
the Last 3 Months
Crowd Wisdom
Very Positive
Last 7 Days ▼ 1.0%
Last 30 Days ▲ 13.0%
Last 30 Days ▲ 13.0%
Technicals
SMA
Positive
20 days / 200 days
Momentum
87.78%
12-Months-Change
Fundamentals
Return on Equity
-94.59%
Trailing 12-Months
Asset Growth
-58.55%
Trailing 12-Months
Company Description
Spero Therapeutics Inc
Spero Therapeutics, Inc. (SPRO) is a clinical-stage biopharmaceutical company dedicated to developing and commercializing novel treatments for bacterial infections, including multi-drug resistant bacterial infections. The company focuses on its proprietary platform in developing a pipeline of therapeutics to address critical unmet medical needs, particularly in the area of gram-negative bacterial infections. Spero's core products include SPR994 (tebipenem HBr), an oral antibiotic candidate for treating complicated urinary tract infections, and SPR720, an oral antibiotic candidate for treating non-tuberculous mycobacterial pulmonary disease.
SPRO Earnings Call
Q2 2025
0:00 / 0:00
Earnings Call Sentiment|Positive
The earnings call reflected a positive outlook with significant achievements, particularly the successful Phase III trial for Tebipenem HBr and the improved financial metrics. However, challenges remain in the SPR720 program. Overall, the positive developments notably outweigh the negative aspects.View all SPRO earnings summariesSPRO Stock 12 Month Forecast
Average Price Target
$4.00
▲(60.00% Upside)
Technical Analysis
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Ownership Overview
8.23% Insiders
4.53% Mutual Funds
0.20% Other Institutional Investors
83.95% Public Companies and
Individual Investors