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Exicure Inc (XCUR)
NASDAQ:XCUR
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Exicure (XCUR) AI Stock Analysis

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XCUR

Exicure

(NASDAQ:XCUR)

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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
$3.00
▼(-49.41% Downside)
Action:Reiterated
Date:05/30/26
The score is primarily held down by weak financial performance (minimal revenue, sizable ongoing losses, and significant cash burn despite zero debt). Technicals also remain unfavorable with the price below major moving averages and negative MACD. Offsetting these negatives, recent corporate events are modestly constructive (governance/legal resolution and leadership changes), but not enough to overcome the fundamental and trend weakness.
Positive Factors
Proprietary SNA platform
Exicure’s proprietary spherical nucleic acid (SNA) platform represents a durable technological moat that can enable differentiated delivery and therapeutic mechanisms across oncology and immunology. Platform ownership supports multiple programs and partnership leverage, strengthening long-term commercial optionality and IP value.
Negative Factors
Near-zero revenue profile
The company’s pre-revenue/near-zero revenue status and recurring operating losses mean no internal product cash generation. Without commercial revenue, Exicure remains dependent on external financing or partnerships to fund R&D, limiting visibility to sustainable earnings and long-term self-sufficiency.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary SNA platform
Exicure’s proprietary spherical nucleic acid (SNA) platform represents a durable technological moat that can enable differentiated delivery and therapeutic mechanisms across oncology and immunology. Platform ownership supports multiple programs and partnership leverage, strengthening long-term commercial optionality and IP value.
Read all positive factors

Exicure (XCUR) vs. SPDR S&P 500 ETF (SPY)

Exicure Business Overview & Revenue Model

Company Description
Exicure, Inc., a biotechnology company, develops therapies for neurological disorders and hair loss based on its proprietary spherical nucleic acid (SNA) technology. Its lead program candidate includes SCN9A that is in preclinical studies for neur...
How the Company Makes Money
null...

Exicure Financial Statement Overview

Summary
Income statement and cash flow are very weak, with near-zero revenue in TTM and persistent losses (TTM net loss about -$9.8M) alongside heavy cash burn (TTM operating and free cash flow about -$8.1M). The balance sheet is partially improved by eliminating debt in TTM, but equity has declined materially (TTM equity about $2.1M), leaving limited cushion while losses continue.
Income Statement
12
Very Negative
Balance Sheet
35
Negative
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.00500.00K0.0028.83M-483.00K
Gross Profit-157.00K-460.00K500.00K-1.42M26.97M-483.00K
EBITDA-8.38M-9.66M-8.85M-15.54M78.00K-60.63M
Net Income-9.78M-4.95M-9.70M-16.91M-2.58M-64.10M
Balance Sheet
Total Assets12.76M14.04M15.06M11.58M23.33M64.87M
Cash, Cash Equivalents and Short-Term Investments2.60M3.75M12.51M816.00K8.58M39.14M
Total Debt0.00176.00K5.93M6.67M7.31M14.74M
Total Liabilities10.66M10.12M8.28M8.55M8.41M53.64M
Stockholders Equity2.10M3.93M6.77M3.03M14.92M11.23M
Cash Flow
Free Cash Flow-8.10M-8.56M-2.91M-10.36M-35.67M-35.79M
Operating Cash Flow-8.10M-8.55M-2.91M-10.36M-35.66M-34.82M
Investing Cash Flow283.00K-1.81M0.00-1.08M4.70M43.09M
Financing Cash Flow0.001.60M13.40M3.67M-3.10M1.12M

Exicure Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price5.93
Price Trends
50DMA
3.63
Negative
100DMA
4.10
Negative
200DMA
4.50
Negative
Market Momentum
MACD
-0.20
Negative
RSI
49.55
Neutral
STOCH
56.33
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For XCUR, the sentiment is Neutral. The current price of 5.93 is above the 20-day moving average (MA) of 3.10, above the 50-day MA of 3.63, and above the 200-day MA of 4.50, indicating a neutral trend. The MACD of -0.20 indicates Negative momentum. The RSI at 49.55 is Neutral, neither overbought nor oversold. The STOCH value of 56.33 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for XCUR.

Exicure Risk Analysis

Exicure disclosed 22 risk factors in its most recent earnings report. Exicure reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Exicure Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$229.11M-1.70-100.13%12.96%12.51%
43
Neutral
$18.93M-2.08-108.76%-100.00%70.40%
42
Neutral
$187.43M-44.17-131.18%-36.64%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
XCUR
Exicure
3.19
-7.27
-69.50%
UNCY
Unicycive Therapeutics
7.38
0.76
11.48%
CRBU
Caribou Biosciences
2.36
1.39
143.30%

Exicure Corporate Events

Business Operations and StrategyExecutive/Board Changes
Exicure Strengthens Leadership With New COO and Director
Positive
Apr 10, 2026
On April 8, 2026, Exicure, Inc. appointed Yoontae Han to its board of directors and named him to the audit committee, while elevating existing member Dongho Lee to chair of that committee, reinforcing its governance and audit oversight structure. ...
Business Operations and StrategyLegal Proceedings
Exicure Reaches Preliminary Settlement in Derivative Lawsuits
Positive
Apr 2, 2026
On March 19, 2026, the U.S. District Court for the Northern District of Illinois preliminarily approved a settlement of stockholder derivative claims brought on behalf of Exicure, Inc. The settlement is designed to fully and finally resolve deriva...
Executive/Board Changes
Exicure Announces Routine Board and Audit Committee Change
Neutral
Mar 27, 2026
On March 25, 2026, Exicure director Sangjin Yeo submitted his resignation from the company’s Board of Directors and its Audit Committee, effective March 27, 2026. The company stated that Yeo’s departure was not due to any disagreement ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 30, 2026