Record Quarterly Revenue and Strong YoY Growth
Total revenue of $68.4M in Q1 2026, up 30% year-over-year and significantly above company guidance.
MACI Outstanding Performance
MACI revenue of $56.4M (+22% YoY); trailing four-quarter MACI revenue growth increased to 23% (from 19% prior period); fourth consecutive quarter with MACI growth ≥20%; Q2 MACI guidance implying ~$62.5M–$63.5M.
Burn Care Momentum and BARDA Award
Burn Care revenue >$12M in Q1, up over 90% YoY; Epicel $10.9M and NexoBrid $1.1M (NexoBrid +~60% vs. Q4); announced BARDA award up to $197M with $35M base contract (including ~$10M in next 12 months) and expected NexoBrid procurement revenue of ~$5M–$6M in H2 2026.
Margin Expansion and Profitability Improvement
Gross margin increased by >300 basis points to 72% in Q1; adjusted EBITDA margin improved nearly 800 basis points to 14%; adjusted EBITDA was ~$9.6M (nearly tripled / +195% YoY per CFO commentary).
Strong Cash Generation and Balance Sheet
Operating cash flow of $16.4M and free cash flow of $15.1M in Q1 (third consecutive quarter with free cash flow ≥$12M); cash and investments ~ $211M, up nearly $50M vs. prior-year period.
Commercial Execution — Sales Force Expansion
First quarter operating with expanded MACI sales force produced record biopsies, implants and biopsy/implanting surgeons; implants and biopsies per surgeon accelerated, with improved biopsy-to-implant pull-through especially in new territories.
MACI Arthro Early Clinical Signals
Investigator case series shows early MACI Arthro benefits (reduced post-op pain, improved range of motion, faster time to full weight bearing); initial data accepted for publication and registry data collection underway.
Operational Milestone — Manufacturing Approval and International Pathway
FDA approval for MACI commercial manufacturing at new Burlington facility increases capacity and enables planned UK marketing application later in 2026 with potential UK launch in 2027.
Raised Full-Year Guidance
Total 2026 revenue guidance increased by $10M to $326M–$336M; MACI guidance raised to $282M–$288M; Burn Care guidance raised to $44M–$48M; company midpoint implies ~20% total revenue growth for 2026.