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Trevi Therapeutics Inc (TRVI)
NASDAQ:TRVI
Nintedanib, Pirfenidone, Nal Er
Healthy Participants
Phase I
Recruiting
A Study of the Pharmacokinetic Interaction Between Pirfenidone, Nintedanib, and Nalbuphine Extended Release (NAL ER) in Healthy Participants
Jun 03, 2025
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Nal Er
Idiopathic Pulmonary Fibrosis
Phase I
Recruiting
NAL ER IPF Respiratory Function and Safety Study
May 29, 2025
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Nal Er
Refractory Chronic Cough
Phase II
Completed
Refractory Chronic Cough Improvement Via NAL ER (RIVER)
Jul 07, 2023
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Nal Er
Idiopathic Pulmonary Fibrosis
Phase II
Completed
Cough Reduction in IPF With Nalbuphine ER
Jul 07, 2023
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Nal Er
Idiopathic Pulmonary Fibrosis
Phase II
Completed
A Study of Nalbuphine (Extended Release) ER in Idiopathic Pulmonary Fibrosis (IPF) for Treatment of Cough
Jul 11, 2019
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Nalbuphine Er, Nalbuphine Er -
Hepatic Impairment, Nalbuphine
Phase I
Unknown
Nalbuphine ER Effects of Liver Disease on Pharmacokinetics and Itch
May 30, 2019
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Nalbuphine Hcl Solution
Nalbuphine, Opioid Abuse
Phase I
Completed
Oral Abuse Potential Study of Nalbuphine
May 30, 2019
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Nalbuphine Er Tablets
Prurigo Nodularis
Phase II/III
Completed
PRISM Study-Pruritus Relief Through Itch Scratch Modulation
Mar 22, 2018
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Nalbuphine Hcl Er
Uremic Pruritus
Phase I
Completed
Phase 1 Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus
Feb 13, 2015
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Nalbuphine Hcl Er Tablets 90 Mg Bid, Nalbuphine Hcl Er Tablets 180 Mg Bid
Pruritus, Prurigo Nodularis, Nodularis Prurigo, Prurigo
Phase II/III
Completed
Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis
Jun 24, 2014
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Trevi Therapeutics Inc (TRVI) have in its pipeline
TRVI is currently developing the following drugs: Nintedanib, Pirfenidone, Nal Er, Nal Er, Nal Er. These drug candidates are in various stages of clinical development as the company works toward FDA approval.