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Traws Pharma (TRAW)
NASDAQ:TRAW

Traws Pharma (TRAW) AI Stock Analysis

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TRAW

Traws Pharma

(NASDAQ:TRAW)

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Neutral 56 (OpenAI - 5.2)
Rating:56Neutral
Price Target:
$2.00
▲(3.09% Upside)
The score is held back primarily by weak financial performance (widening losses, rising cash burn, and negative equity), which elevates funding risk. Offsetting this are strong technical momentum (price above major moving averages with positive MACD) and multiple positive corporate catalysts tied to COVID and influenza pipeline progress, while valuation metrics are not supportive/meaningful given the loss-making profile.
Positive Factors
Pipeline clinical progress
Completing Phase 2 enrollment with favorable interim safety and efficacy signals materially raises the likelihood of clear next-step data readouts and regulatory discussions. Durable clinical momentum strengthens the company’s positioning versus ritonavir-based options and supports long-term commercial potential.
Regulatory pathway and strategic stockpile relevance
An IND filing that positions a compound for BARDA consideration creates a structural commercial channel beyond retail sales. Inclusion in strategic stockpiles or government programs can produce stable, large-volume demand and de-risks revenue concentration for a clinical-stage antiviral developer over multiple years.
No debt on balance sheet
A debt-free capital structure lowers fixed financial obligations and interest expense, preserving operational flexibility while advancing costly clinical programs. For a pre-commercial biotech, absence of leverage improves resilience to revenue variability and reduces bankruptcy/default tail risk.
Negative Factors
Widening losses and accelerating cash burn
Rapidly increasing net losses and operating cash outflows materially shorten runway and raise near-term external funding needs. This structural cash consumption elevates dilution and execution risk, potentially forcing financing or program prioritization that could delay or curtail planned clinical milestones.
Negative shareholders' equity
Negative equity reflects accumulated operating losses that weaken balance-sheet cushioning and limit borrowing capacity. This persistent deficit diminishes counterparty confidence and can complicate partnership, licensing, or supplier negotiations, increasing structural funding and operational fragility.
Minimal and immaterial revenue base
With negligible recurring revenue, the business remains fully dependent on R&D milestones and external capital. Lack of diversified commercial income means trial outcomes and financing cycles will determine sustainability, increasing long-term execution risk absent successful product approvals or durable partnerships.

Traws Pharma (TRAW) vs. SPDR S&P 500 ETF (SPY)

Traws Pharma Business Overview & Revenue Model

Company DescriptionTraws Pharma, Inc., a clinical stage biopharmaceutical company, focuses on developing small molecule oral product candidates for respiratory viral diseases and cancer. The company is developing investigational novel therapies for influenza and COVID19 that are designed to address treatment resistance, such as TRX01 (travatrelvir), a Mpro/3CL inhibitor in development for the treatment of COVID19; and TRX100 (viroxavir), an endonuclease inhibitor in development for the treatment of pandemic influenza. It is also developing narazaciclib, a multi-kinase CDK4/6 inhibitor, which is in Phase 1/2 clinical trials in patients with cancer, with or without co-administration of letrozole to define the recommended phase 2 dose for further development in endometrial cancer; and oral rigosertib, which is administered alone or in combination for investigation in various cancers. The company was formerly known as Onconova Therapeutics, Inc. and changed its name to Traws Pharma, Inc. in April 2024. Traws Pharma, Inc. was incorporated in 1998 and is headquartered in Newtown, Pennsylvania.
How the Company Makes MoneyTraws Pharma generates revenue primarily through the sale of its pharmaceutical products and therapies that have gained regulatory approval. The company also engages in licensing agreements, where it grants other pharmaceutical firms access to its proprietary technologies and compounds in exchange for upfront payments, milestone fees, and royalties on sales. Additionally, Traws Pharma may receive funding from research grants and collaborations with academic institutions or other industry players. Strategic partnerships with larger pharmaceutical companies also contribute to its earnings, facilitating the co-development and co-promotion of new therapies.

Traws Pharma Earnings Call Summary

Earnings Call Date:Aug 14, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Mar 12, 2026
Earnings Call Sentiment Neutral
Traws Pharma has made notable advancements in its antiviral programs, particularly with Ratutrelvir for COVID-19. Regulatory engagement and a significant increase in revenue highlight positive progress. However, challenges such as deferred influenza studies and reduced cash reserves present concerns. Overall, highlights slightly outweigh the lowlights, indicating a cautiously optimistic outlook.
Q2-2025 Updates
Positive Updates
Strong Progress in Antiviral Development
Traws Pharma has reprioritized its clinical trial plans, advancing Ratutrelvir for COVID treatment, with Phase II study results expected by year-end 2025.
Potential Market Opportunity for Ratutrelvir
Ratutrelvir is targeted to address a $1.5 billion annual market opportunity for individuals ineligible for PAXLOVID, expanding COVID-19 treatment access.
Engagement with Regulatory Authorities
Approval of Phase II bird flu/seasonal flu protocol by Australian and South Korean regulatory authorities, allowing quick study initiation if bird flu incidence rates increase.
Increase in Revenue
Revenue for Q2 2025 was $2.7 million, a significant increase from $57,000 in the same period of 2024, due to deferred revenue recognition from a terminated licensing agreement.
Reduced Net Loss
Net loss for Q2 2025 was $0.9 million compared to $123.1 million in Q2 2024, showing improved financial management.
Negative Updates
Decrease in R&D and G&A Expenses
R&D expenses fell to $2.3 million from $4 million, and G&A expenses decreased to $1.7 million from $2 million, indicating reduced investment in some areas.
Deferred Influenza Program
Initiation of bird flu Phase II study has been deferred due to low recruitment likelihood, potentially delaying progress in this area.
Cash Reserves Decline
Cash and short-term investments decreased to $13.1 million from $21.3 million as of December 31, 2024, indicating reduced liquidity.
Company Guidance
During the second quarter of 2025, Traws Pharma provided guidance on their strategic focus areas, highlighting significant developments in their antiviral and influenza programs. They are advancing ratutrelvir, a ritonavir-free treatment for COVID-19, into Phase II studies, expecting results by the end of 2025, which could tap into a $1.5 billion market opportunity. Ratutrelvir aims to address the limitations of PAXLOVID, which saw a 70% sales increase to $427 million this quarter, by offering a longer treatment duration of 10 days and avoiding drug-drug interactions caused by ritonavir. Traws is also in discussions with BARDA for tivoxavir marboxil's potential inclusion in drug stockpiles for influenza, including bird flu, with recent protocol approvals in Australia and South Korea. Financially, Traws reported a net loss of $0.9 million for the quarter, a significant improvement from the $123.1 million loss in the same period of 2024, due to recognizing $2.7 million in deferred revenue following a licensing agreement termination. The company's cash reserves stood at $13.1 million, down from $21.3 million at the end of 2024.

Traws Pharma Financial Statement Overview

Summary
Financial statements reflect a pre-commercial biotech with immaterial and largely flat revenue, materially widening losses (net loss ~$54.7M in 2024 vs. ~$18.9M in 2023), and worsening operating cash burn (~-$29.8M in 2024 vs. ~-$17.9M in 2023). No debt is a positive, but the move to negative equity in 2024 increases funding risk.
Income Statement
8
Very Negative
Revenue is very small and largely flat in recent years (~$226K annually), despite a sharp reported growth rate in 2024 that still leaves the revenue base immaterial. Gross margin is high (typical of biotech), but the cost structure is far too large for the current revenue level: operating losses widened materially in 2024 (net loss ~$54.7M vs. ~$18.9M in 2023), driving extremely negative profitability. Overall, the income statement reflects a pre-commercial business with accelerating losses and limited near-term earnings visibility.
Balance Sheet
18
Very Negative
The company reports no debt, which reduces financial risk and interest burden. However, equity turned negative in 2024 (stockholders’ equity about -$31.6M vs. +$10.7M in 2023), signaling substantial accumulated losses and weakening balance-sheet cushioning. Total assets are modest (~$25.0M in 2024) and down versus earlier years, which can constrain flexibility if cash needs persist.
Cash Flow
12
Very Negative
Cash burn remains significant and is moving in the wrong direction: operating cash flow was about -$29.8M in 2024 versus -$17.9M in 2023, with free cash flow similarly negative. Free cash flow is consistently negative across the period, indicating ongoing reliance on external funding. While cash flow tracks net losses closely (losses are being realized in cash), the key takeaway is sustained and increasing cash consumption.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue2.79M226.00K226.00K226.00K226.00K231.00K
Gross Profit2.79M214.00K226.00K226.00K226.00K231.00K
EBITDA-10.97M-166.51M-20.28M-19.61M-16.48M-24.98M
Net Income-9.10M-54.67M-18.95M-18.96M-16.16M-25.16M
Balance Sheet
Total Assets15.62M24.96M22.68M39.37M55.48M19.99M
Cash, Cash Equivalents and Short-Term Investments13.08M21.34M20.82M38.76M55.07M19.02M
Total Debt0.000.000.000.000.000.00
Total Liabilities7.36M56.59M12.01M11.06M9.36M13.81M
Stockholders Equity8.26M-31.63M10.67M28.31M46.12M6.17M
Cash Flow
Free Cash Flow-10.02M-29.79M-17.95M-16.29M-19.49M-23.09M
Operating Cash Flow-10.02M-29.79M-17.93M-16.29M-19.49M-23.07M
Investing Cash Flow0.00-3.65M-14.00K0.000.00-15.00K
Financing Cash Flow23.07M33.98M0.000.0055.56M19.36M

Traws Pharma Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.94
Price Trends
50DMA
1.94
Negative
100DMA
2.12
Negative
200DMA
1.82
Positive
Market Momentum
MACD
0.11
Positive
RSI
47.89
Neutral
STOCH
10.69
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TRAW, the sentiment is Negative. The current price of 1.94 is below the 20-day moving average (MA) of 2.04, below the 50-day MA of 1.94, and above the 200-day MA of 1.82, indicating a neutral trend. The MACD of 0.11 indicates Positive momentum. The RSI at 47.89 is Neutral, neither overbought nor oversold. The STOCH value of 10.69 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TRAW.

Traws Pharma Risk Analysis

Traws Pharma disclosed 46 risk factors in its most recent earnings report. Traws Pharma reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Traws Pharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$15.50M0.087432.32%1159.29%
52
Neutral
$41.55M-2.22-71.45%15.32%
52
Neutral
$21.49M-0.69-380.13%54.41%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TRAW
Traws Pharma
1.94
-6.35
-76.60%
LSTA
Lisata Therapeutics
4.71
2.07
78.41%
LEXX
Lexaria Bioscience
0.72
-1.17
-61.69%
HOTH
Hoth Therapeutics
0.80
-0.40
-33.17%
APLM
Apollomics
19.48
11.18
134.70%

Traws Pharma Corporate Events

Business Operations and StrategyProduct-Related Announcements
Traws Pharma Completes Phase 2 Enrollment for COVID Candidate
Positive
Jan 26, 2026

On January 26, 2026, Traws Pharma reported it had completed enrollment in a 90-patient open-label Phase 2 study of its oral COVID-19 candidate ratutrelvir, comparing it with PAXLOVID in PAXLOVID-eligible patients and in a separate cohort of patients ineligible for ritonavir-based regimens, a group often at higher risk of severe disease. Interim clinical observations highlighted fewer adverse events, absence of viral rebound to date, faster and sustained symptom resolution, and favorable tolerability for ratutrelvir, reinforcing its potential to address a sizeable market segment that cannot use ritonavir and to offer a differentiated profile that may also have implications for reducing post-acute sequelae of SARS-CoV-2 infection. The company also advanced its influenza franchise, outlining plans to pursue an additional indication for tivoxavir marboxil as a once-monthly oral prophylactic for seasonal influenza, supported by earlier Phase 1 data showing prolonged therapeutic blood levels and a new compressed tablet formulation expected to provide 28 days of protection, with a human influenza prophylaxis challenge study already scheduled for June 2026, positioning Traws for multiple upcoming clinical and value inflection points in the multi-billion-dollar antiviral market for COVID-19 and flu.

The most recent analyst rating on (TRAW) stock is a Buy with a $3.00 price target. To see the full list of analyst forecasts on Traws Pharma stock, see the TRAW Stock Forecast page.

Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Traws Pharma advances flu and COVID-19 antiviral pipeline
Positive
Jan 13, 2026

On January 13, 2026, Traws Pharma filed a U.S. Investigational New Drug application with the FDA for tivoxavir marboxil (TXM), a potential best-in-class, single-dose oral CAP-dependent endonuclease inhibitor for the treatment of seasonal and avian influenza, a move that represents the final step toward formal consideration by BARDA for inclusion in the U.S. strategic national stockpile. In a separate update from an ongoing randomized Phase 2 trial in mild-to-moderate COVID-19, the company reported interim data in 50 patients showing that ratutrelvir, its ritonavir-free oral 3CL protease inhibitor, delivered faster sustained symptom resolution than PAXLOVID, no observed viral or symptom rebound events, fewer adverse effects and favorable tolerability, including in PAXLOVID-ineligible patients at higher risk of severe disease, reinforcing Traws’ bid to position ratutrelvir as a next-generation COVID-19 therapy and to expand its role in both acute treatment and potential long-COVID prevention strategies.

The most recent analyst rating on (TRAW) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on Traws Pharma stock, see the TRAW Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Traws Pharma Reports Positive Phase 2 Trial Results
Positive
Dec 17, 2025

Traws Pharma announced positive interim results from a Phase 2 trial of ratutrelvir, a ritonavir-free oral COVID-19 treatment, on December 17, 2025. The data highlighted a favorable safety profile, no viral rebounds, and potential benefits for patients ineligible for Paxlovid due to contraindications, as well as its potential role in Long COVID prevention. With a differentiated clinical profile, this investigational treatment positions Traws Pharma as a key contender in the multi-billion-dollar COVID-19 therapeutic market.

The most recent analyst rating on (TRAW) stock is a Buy with a $8.00 price target. To see the full list of analyst forecasts on Traws Pharma stock, see the TRAW Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Traws Pharma Approves Executive Stock Options
Neutral
Dec 16, 2025

On December 12, 2025, Traws Pharma‘s Compensation Committee approved stock options and restricted stock units for its executive officers. This decision, under the 2021 Incentive Compensation Plan, aims to incentivize key leaders, potentially impacting the company’s operational focus and market positioning.

The most recent analyst rating on (TRAW) stock is a Buy with a $8.00 price target. To see the full list of analyst forecasts on Traws Pharma stock, see the TRAW Stock Forecast page.

Shareholder Meetings
Traws Pharma Holds Virtual Annual Meeting 2025
Neutral
Nov 28, 2025

On November 21, 2025, Traws Pharma held its Annual Meeting virtually, with 48% of its outstanding shares represented. During the meeting, stockholders elected seven directors, approved amendments to the 2021 Incentive Compensation Plan, and ratified KPMG LLP as the independent auditor for 2025. Additionally, it was decided that advisory votes on executive compensation will occur every two years, with the next vote scheduled for the 2027 Annual Meeting.

Business Operations and StrategyFinancial Disclosures
Traws Pharma Reports Q3 2025 Financial Results
Positive
Nov 13, 2025

On November 13, 2025, Traws Pharma announced its financial results for the quarter ending September 30, 2025, highlighting significant cost reductions and the acquisition of intellectual property assets. The company is advancing its Phase 2 studies for ratutrelvir, a potential COVID-19 therapy, and tivoxavir marboxil for bird flu and seasonal flu, both representing substantial market opportunities. The company also reported management updates and a decrease in net loss compared to the previous year, indicating a strategic shift towards antiviral programs and partnerships for legacy oncology assets.

The most recent analyst rating on (TRAW) stock is a Buy with a $6.00 price target. To see the full list of analyst forecasts on Traws Pharma stock, see the TRAW Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 27, 2026