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Sarepta Therapeutics (SRPT)
NASDAQ:SRPT
US Market

Sarepta Therapeutics (SRPT) Earnings Dates, Call Summary & Reports

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Earnings Data

Report Date
May 06, 2026
After Close (Confirmed)
Period Ending
2026 (Q1)
Consensus EPS Forecast
1.09
Last Year’s EPS
-4.6
Same Quarter Last Year
Based on 19 Analysts Ratings

Earnings Call Summary

Q4 2025
Earnings Call Date:Feb 25, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
The call balanced material near-term challenges (safety-related market uncertainty, substantial inventory/manufacturing charges and reported operating losses) with strong underlying positives: robust revenue growth in 2025, a solid cash position, compelling and durable three‑year ELEVIDYS efficacy data, a stable PMO franchise, a rapidly advancing siRNA pipeline with multiple clinical programs and clear 2026 financial guidance. Management emphasized plans to address information deficits, commercial expansion and pipeline milestones; timing risk for ELEVIDYS uptake and non-ambulatory resumption remains notable.
Company Guidance
Sarepta gave broad 2026 financial guidance and key metrics: net product revenue of $1.2–$1.4 billion (Q1 expected about flat to down ~15% vs. prior quarter), 2026 non‑GAAP R&D+SG&A of $800–$900 million, and the company expects to be cash‑flow positive and non‑GAAP profitable in 2026 under reasonable scenarios. They closed 2025 with $954 million cash & investments (up $89 million in Q4) and base business positive cash flow >$330 million ex‑Arrowhead; full‑year 2025 results were $2.2 billion total revenue (+16% YoY) including $1.86 billion net product revenue ($966M PMO franchise, $899M ELEVIDYS) and $334 million collaboration/CM/royalty revenue. Q4 detail: PMO net product revenue $259M (EXONDYS $148M, VYONDYS $34M, AMONDYS $77M) and ELEVIDYS $110M (impacted by a severe flu season and six rescheduled infusions); Q4 cost of sales $399M (including a $193M charge — $165M noncash inventory reserve + $28M purchase‑commitment fees), FY COS $840M. For 2026 they expect collaboration/CM/royalty revenue of $450–$550M (including a $40M Roche Q1 milestone and ~$325M noncash collaboration revenue tied to Roche), project unit margins in the high‑70% range for 2026 (2025 unit margins were low‑80% excluding period charges), and note balance‑sheet actions that refinanced $291M of 2027 notes into 2030 leaving a $159M remaining stub.
Strong full-year revenue growth
Total revenues for FY2025 were $2.2 billion, up 16% year-over-year, including $1.86 billion in net product revenue (PMOs $966M; ELEVIDYS $899M) showing continued commercial traction.
Solid cash position and positive core cash generation
Ended 2025 with $954 million in cash and investments (up $89M in Q4); base business (ex-Arrowhead payments) generated more than $330 million of positive cash flow in 2025 and management expects to be cash-flow positive and non-GAAP profitable in 2026 under reasonable scenarios.
ELEVIDYS durable, disease-modifying data (EMBARK 3-year)
Three-year EMBARK Part 1 results show durable, statistically significant efficacy vs external control: 73% slowing in disease progression for time-to-rise, 70% for 10m walk/run, NSAA +4.39 point difference at year 3 (p=0.0002); no new safety signals reported through three years.
PMO franchise stability and compliance
PMO net product revenue totaled $966 million in 2025; Q4 PMO revenue $259 million (EXONDYS $148M, VYONDYS $34M, AMONDYS $77M) with year-after-year compliance rates consistently over 90%.
Pipeline advancement: multiple clinical-stage siRNA programs
Five clinical-stage siRNA programs advancing (DM1 SRP-1003, FSHD, IPF, SCA2, Huntington's SRP-1005 initiated), with additional preclinical programs (SCA1, SCA3) and planned readouts (preliminary DM1/FSHD data end of quarter; further PD/splice data later in 2026).
Regulatory and commercial milestones
ELEVIDYS received traditional approval for ambulatory patients and approval to run a sirolimus pretreatment study for non-ambulatory patients; meeting with FDA scheduled to discuss transitioning AMONDYS and VYONDYS to traditional approval following ESSENCE confirmatory data.
2026 revenue and collaboration visibility
Provided net product revenue guidance for 2026 of $1.2B–$1.4B (management advises modeling toward the low end given timing uncertainty) and expects collaboration, contract manufacturing, and royalty revenues of $450M–$550M in 2026 (including a $40M Roche milestone and ~$325M noncash collaboration revenue).

Sarepta Therapeutics (SRPT) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

SRPT Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
May 06, 2026
2026 (Q1)
1.09 / -
-4.6
Feb 25, 2026
2025 (Q4)
-1.20 / -3.93
1.5-362.00% (-5.43)
Nov 03, 2025
2025 (Q3)
-0.73 / -1.80
0.34-629.41% (-2.14)
Aug 06, 2025
2025 (Q2)
0.83 / 1.89
0.072600.00% (+1.82)
May 06, 2025
2025 (Q1)
-3.21 / -4.60
0.37-1343.24% (-4.97)
Feb 26, 2025
2024 (Q4)
1.88 / 1.50
0.47219.15% (+1.03)
Nov 06, 2024
2024 (Q3)
-0.07 / 0.34
-0.46173.91% (+0.80)
Aug 07, 2024
2024 (Q2)
-0.13 / 0.07
-0.27125.93% (+0.34)
May 01, 2024
2024 (Q1)
0.01 / 0.37
-5.86106.31% (+6.23)
Feb 28, 2024
2023 (Q4)
0.07 / 0.47
-1.24137.90% (+1.71)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

SRPT Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
Feb 25, 2026
$18.97
Nov 03, 2025
$24.45$16.20-33.74%
Aug 06, 2025
$16.26$17.96+10.46%
May 06, 2025
$46.75$36.72-21.45%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Sarepta Therapeutics (SRPT) report earnings?
Sarepta Therapeutics (SRPT) is schdueled to report earning on May 06, 2026, After Close (Confirmed).
    What is Sarepta Therapeutics (SRPT) earnings time?
    Sarepta Therapeutics (SRPT) earnings time is at May 06, 2026, After Close (Confirmed).
      Where can I see when companies are reporting earnings?
      You can see which companies are reporting today on our designated earnings calendar.
        What companies are reporting earnings today?
        You can see a list of the companies which are reporting today on TipRanks earnings calendar.
          What is SRPT EPS forecast?
          SRPT EPS forecast for the fiscal quarter 2026 (Q1) is 1.09.

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