Strong Revenue Growth
Total revenue of $21.7M in Q1 2026, up 22% year-over-year from $17.8M in Q1 2025; company reaffirmed full-year 2026 revenue guidance of $92M–$94M (20%–22% growth).
Record and Growing Analysis Volume
Platform analysis volume reached ~108,000 in Q1 (up 16% YoY from 93,000) with a company record of >40,000 patients analyzed in March and 2.5M cumulative genomic profiles since inception.
High Adjusted Gross Margin and Profitability Progress
Adjusted gross margin of 75.4% in Q1 2026 (75.7% in Q1 2025) and adjusted gross profit of $16.4M, up 22% YoY; company expects modest gross margin expansion for 2026 and reaffirmed full-year adjusted EBITDA loss guidance of $29M–$32M (improved versus $41.5M in 2025).
Customer Base and Retention Strength
Core genomic customers increased to 537 (from 490 year-over-year); annualized revenue churn remained under 1%; net dollar retention improved to 117% (up from 103% YoY), indicating strong same-store expansion.
Regional and Application Momentum
U.S. volumes grew 28% YoY and APAC volumes grew 31%; EMEA revenue grew ~30% YoY (outperforming company average). Hem/Onc revenue grew 24% YoY and Rare/inherited volumes rose >20% as enhanced exome ramps.
Liquid Biopsy and New Application Adoption
3,000 liquid biopsy analyses in Q1 (up >100% YoY); 100 customers signed for MSK Impact/MSK Access in <2 years, with ~50% currently implementing PBM (expected revenue within 12 months).
Biopharma Momentum and Strategic Partnerships
Increasing biopharma traction with new contracts and partnerships including AstraZeneca, Johnson & Johnson, Kartos, and collaboration progress with Myriad; biopharma contributions turned modestly positive in Q1 and are expected to accelerate into 2027.
Capital and Liquidity Actions
Ended Q1 with $65.4M cash and equivalents (includes $14.5M ATM proceeds) and expanded credit facility by $25M with Perceptive Advisors, bolstering liquidity to support growth and litigation defense.
Operational Efficiency and AI-driven Cost Actions
Targeted cost actions in Q1 modestly reduced headcount and non-labor spend (focused on G&A and support/operations) and early internal rollout of productivity AI tools produced positive early results supporting operating leverage.
Technology and Long-term Strategic Positioning
Company reports scalable, hyper-efficient analytics platform with a unique global data footprint (data from 75 countries), prioritizing expansion into large NGS applications, MRD, multimodal capabilities and durable RWE/CDx offerings.