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Semler Scientific (SMLR)
NASDAQ:SMLR

Semler Scientific (SMLR) AI Stock Analysis

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SMLR

Semler Scientific

(NASDAQ:SMLR)

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Neutral 54 (OpenAI - 4o)
Rating:54Neutral
Price Target:
$19.50
▼(-5.66% Downside)
Semler Scientific's overall stock score reflects significant operational and cash flow challenges, despite a strong balance sheet and undervaluation. The bearish technical indicators and recent legal and revenue challenges further weigh on the score. However, strategic initiatives like the merger with Strive, Inc. could provide future growth opportunities if successfully executed.
Positive Factors
Strategic Realignment
The strategic realignment plan aims to improve operating leverage and reduce expenses, potentially enhancing long-term operational efficiency and profitability.
Merger with Strive, Inc.
The merger with Strive, Inc. could expand market reach and create synergies, enhancing competitive positioning and growth prospects in the healthcare sector.
Strong Balance Sheet
A strong balance sheet with low leverage provides financial stability and flexibility, supporting long-term strategic initiatives and resilience against economic fluctuations.
Negative Factors
Declining Revenue
Declining revenue indicates challenges in maintaining market share and product demand, which could impact long-term growth and profitability if not addressed.
Operational Challenges
Operational inefficiencies reflected in negative margins could hinder profitability and require strategic adjustments to improve cost management and operational effectiveness.
Cash Flow Issues
Cash flow challenges can limit the company's ability to invest in growth opportunities and meet financial obligations, impacting long-term financial health.

Semler Scientific (SMLR) vs. SPDR S&P 500 ETF (SPY)

Semler Scientific Business Overview & Revenue Model

Company DescriptionSemler Scientific, Inc. provides technology solutions to improve the clinical effectiveness and efficiency of healthcare providers in the United States. The company's products include QuantaFlo, a four-minute in-office blood flow test that enables healthcare providers to use blood flow measurements as part of their examinations of a patient's vascular condition. Its products serve cardiologists, internists, nephrologists, endocrinologists, podiatrists, and family practitioners, as well as healthcare insurance plans, integrated delivery networks, independent physician groups, and companies contracting with the healthcare industry, such as risk assessment groups. The company offers its products through salespersons and distributors. Semler Scientific, Inc. was incorporated in 2007 and is headquartered in Santa Clara, California.
How the Company Makes MoneySemler Scientific generates revenue primarily through the sale of its medical devices and related software solutions. The company's revenue model is based on direct sales to healthcare providers, including hospitals and clinics, as well as partnerships with pharmaceutical companies for integrated health solutions. Additionally, Semler may benefit from recurring revenue streams through service contracts, maintenance agreements, and software subscriptions. Key partnerships with healthcare organizations and participation in clinical studies also contribute to its earnings by expanding market reach and enhancing product credibility.

Semler Scientific Earnings Call Summary

Earnings Call Date:Aug 04, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Mar 10, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted significant achievements in Bitcoin accumulation and financial performance, although the decline in healthcare revenues and operating losses presented challenges. The company's strategic initiatives in Bitcoin and healthcare expansion suggest optimism for future growth.
Q2-2025 Updates
Positive Updates
Record Bitcoin Holdings
During the second quarter of 2025, Semler Scientific acquired approximately $195 million of Bitcoin, holding a total of approximately $586 million worth of Bitcoin. This resulted in an unrealized gain of $110 million.
Strong Financial Performance
Semler Scientific reported a GAAP net income of $66.9 million or $5.04 per fully diluted share for the second quarter of 2025.
Expansion of Health Care Business
Plans to launch new products in larger markets through a subsidiary called CardioVanta, with focus areas in early detection of heart failure and cardiac arrhythmia.
Accretive Bitcoin Strategy
Since adopting the Bitcoin standard in May 2024, Semler has achieved a 300% positive Bitcoin yield, resulting in a BTC dollar gain of $195 million through July 31, 2025.
Negative Updates
Decline in Revenue
Total revenues in Q2 2025 were $8.2 million, down compared to the second quarter of 2024 due to decreased usage of Semler's device following the 2024 CMS rate announcement.
Operating Loss
Operating expenses for Q2 2025 were $10.3 million, leading to a loss from operations of $1.2 million.
Legal Expenses and DOJ Settlement
In Q2 2025, Semler incurred $0.5 million of legal expenses related to a DOJ settlement agreement.
Company Guidance
During the Semler Scientific Second Quarter 2025 Financial Results Conference Call, significant guidance was provided regarding the company's dual-engine strategy focusing on Bitcoin and healthcare. Key metrics highlighted include the acquisition of approximately $2,723 Bitcoin in 2025, totaling a holding of 5,021 Bitcoin valued at $586 million, with unrealized gains of $110 million. The company aims to reach 10,000 Bitcoin by year-end 2025 and 105,000 by year-end 2027. Financially, Semler reported a GAAP net income of $66.9 million or $5.04 per fully diluted share, with a notable Bitcoin yield of 31%. The company also issued 4.1 million shares in Q2 under its ATM offering, generating $156.6 million in proceeds. In healthcare, despite headwinds affecting revenues, a record cash generation of $24 million was achieved in 2024. The company launched a subsidiary, CardioVanta, to focus on new healthcare products, aiming to unlock substantial value in larger markets.

Semler Scientific Financial Statement Overview

Summary
Semler Scientific faces operational and cash flow challenges despite a strong balance sheet. The income statement reflects declining revenue and negative operational margins, while the cash flow statement highlights liquidity issues. The balance sheet remains robust with low leverage and good equity utilization, but the company needs to address its operational inefficiencies and cash flow management to improve its financial health.
Income Statement
The income statement shows a significant decline in revenue with a negative growth rate of -14.01% in the TTM period. Despite a high gross profit margin of 90.85%, the company is experiencing negative EBIT and EBITDA margins, indicating operational challenges. The net profit margin remains strong at 86.20%, primarily due to non-operational factors. Overall, the income statement reflects declining revenue and operational inefficiencies.
Balance Sheet
The balance sheet is relatively strong with a low debt-to-equity ratio of 0.25, indicating low leverage. The return on equity is healthy at 17.21%, showing efficient use of equity. The equity ratio is solid, suggesting a stable financial structure. However, the increase in total debt in the TTM period could be a potential risk if not managed properly.
Cash Flow
The cash flow statement reveals challenges with negative operating and free cash flows in the TTM period. The free cash flow growth rate is positive at 26.33%, but this is from a negative base. The operating cash flow to net income ratio is low at 0.34, indicating cash flow issues relative to reported earnings. Overall, cash flow management appears to be a significant concern.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue36.96M56.29M68.18M56.69M53.03M38.60M
Gross Profit33.54M51.53M61.20M52.43M46.91M35.25M
EBITDA-46.64M21.51M23.59M17.79M20.08M17.06M
Net Income48.34M40.90M20.58M14.32M17.22M14.01M
Balance Sheet
Total Assets596.68M239.83M78.06M62.69M50.67M34.64M
Cash, Cash Equivalents and Short-Term Investments10.18M14.92M57.20M43.09M37.32M22.08M
Total Debt116.42M70.00K160.00K245.00K325.00K0.00
Total Liabilities136.93M9.08M6.27M7.02M5.13M4.85M
Stockholders Equity459.75M230.75M71.80M55.68M45.55M29.79M
Cash Flow
Free Cash Flow-388.75M-165.34M16.99M15.30M15.23M14.36M
Operating Cash Flow-26.91M24.41M17.82M17.46M16.06M15.11M
Investing Cash Flow-405.76M-189.98M18.40M-26.84M-825.00K-1.01M
Financing Cash Flow436.28M117.19M-1.90M-4.94M13.00K230.00K

Semler Scientific Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price20.67
Price Trends
50DMA
20.90
Negative
100DMA
24.78
Negative
200DMA
30.78
Negative
Market Momentum
MACD
-0.17
Negative
RSI
56.19
Neutral
STOCH
76.40
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SMLR, the sentiment is Neutral. The current price of 20.67 is above the 20-day moving average (MA) of 17.93, below the 50-day MA of 20.90, and below the 200-day MA of 30.78, indicating a neutral trend. The MACD of -0.17 indicates Negative momentum. The RSI at 56.19 is Neutral, neither overbought nor oversold. The STOCH value of 76.40 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for SMLR.

Semler Scientific Risk Analysis

Semler Scientific disclosed 50 risk factors in its most recent earnings report. Semler Scientific reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Semler Scientific Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$846.89M-15.93-59.78%
58
Neutral
$703.26M-53.71-3.36%-2.18%-30.96%
54
Neutral
$316.10M7.4317.74%-37.29%62.60%
52
Neutral
$461.17M-9.58-12.67%19.90%-57.90%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$528.18M-7.66-13.95%4.14%-45.29%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SMLR
Semler Scientific
20.67
-30.69
-59.75%
VREX
Varex Imaging
13.24
-0.13
-0.97%
KIDS
OrthoPediatrics
18.73
-5.71
-23.36%
CTKB
Cytek Biosciences
5.43
-1.39
-20.38%
CBLL
Ceribell, Inc.
23.07
2.14
10.22%

Semler Scientific Corporate Events

Business Operations and StrategyM&A Transactions
Semler Scientific Announces Strategic Realignment Plan
Negative
Dec 12, 2025

On December 12, 2025, Semler Scientific announced a strategic realignment plan approved by its board, which includes a 37% reduction in headcount and other expense curtailments to improve operating leverage. This move is expected to reduce quarterly operating expenses by $0.7 million to $1.1 million starting January 2026, with severance costs estimated at $1.2 million. Additionally, Semler Scientific is implementing a cash retention program for non-executive employees to ensure continuity during its pending merger with Strive, Inc., which was initially agreed upon on September 22, 2025. The merger is an all-stock transaction aimed at strategic and financial benefits for the combined company.

The most recent analyst rating on (SMLR) stock is a Hold with a $20.50 price target. To see the full list of analyst forecasts on Semler Scientific stock, see the SMLR Stock Forecast page.

Business Operations and StrategyM&A Transactions
Semler Scientific Announces Merger with Strive, Inc.
Neutral
Nov 14, 2025

On September 22, 2025, Semler Scientific entered into a Merger Agreement with Strive, Inc., which will acquire Semler in an all-stock transaction. This merger positions Strive as the accounting acquirer, with Semler becoming a wholly-owned subsidiary, and is expected to bring strategic and financial benefits to the combined entity. The transaction, however, is subject to various risks and uncertainties, including potential volatility in Bitcoin, which is part of Semler’s treasury strategy, and the challenges of integrating the two companies.

The most recent analyst rating on (SMLR) stock is a Hold with a $27.00 price target. To see the full list of analyst forecasts on Semler Scientific stock, see the SMLR Stock Forecast page.

Product-Related AnnouncementsRegulatory Filings and Compliance
Semler Scientific Launches Bitcoin Holdings Dashboard
Neutral
Nov 12, 2025

Semler Scientific has launched a website dashboard to disclose information about its Bitcoin holdings, including key performance indicators and market data. This initiative aims to ensure compliance with disclosure obligations and provide investors with regular updates on Bitcoin-related information.

The most recent analyst rating on (SMLR) stock is a Hold with a $31.00 price target. To see the full list of analyst forecasts on Semler Scientific stock, see the SMLR Stock Forecast page.

M&A TransactionsPrivate Placements and Financing
Semler Scientific Announces Merger with Strive, Inc.
Neutral
Nov 10, 2025

On September 22, 2025, Semler Scientific, Inc. entered into a merger agreement with Strive, Inc., whereby Strive will acquire Semler in an all-stock transaction. This merger is subject to various terms and conditions, and the companies have disclosed potential risks and uncertainties associated with the transaction, such as integration challenges and market conditions. Strive, Inc. also announced the closing of its initial public offering of Variable Rate Series A Perpetual Preferred Stock, raising approximately $149.3 million. The proceeds were used to purchase bitcoin and for general corporate purposes, increasing Strive’s bitcoin holdings significantly.

The most recent analyst rating on (SMLR) stock is a Hold with a $31.00 price target. To see the full list of analyst forecasts on Semler Scientific stock, see the SMLR Stock Forecast page.

Business Operations and StrategyM&A Transactions
Semler Scientific Merges with Strive in Stock Deal
Neutral
Nov 6, 2025

On September 22, 2025, Semler Scientific, Inc. entered into a merger agreement with Strive, Inc., allowing Strive to acquire Semler in an all-stock transaction. The merger aims to integrate the businesses, potentially impacting their market positioning and financial performance. Strive disclosed its financial activities, including cash reserves, bitcoin holdings, and plans for a public offering of preferred stock, reflecting its strategic focus on strengthening its financial position and expanding its asset management operations.

The most recent analyst rating on (SMLR) stock is a Hold with a $31.00 price target. To see the full list of analyst forecasts on Semler Scientific stock, see the SMLR Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 13, 2025