Clinical Efficacy And SafetySkye’s Phase 2a CBeyond data confirmed nimacimab’s biological activity with a statistically significant nearly 3% incremental benefit in combination with semaglutide, improved body composition, and rebound mitigation, all with a clean safety profile.
Market PotentialNimacimab has the potential to become the 'ezetimibe of obesity', layered onto GLP-1s to sustain weight loss, reduce rebound, and improve tolerability.
Strategic ValueRebound mitigation and lean-mass preservation add strategic value, positioning nimacimab for induction-plus-maintenance regimens if monotherapy approval can be secured for maintenance labeling.