Acne Franchise And CommercializationStrong Phase III data from partner Ascletis for denifanstat, coupled with plans to initiate a Phase 2 trial for TVB‑3567 in moderate‑to‑severe acne, expands commercial opportunity in a sizable acne market.
Clinical DevelopmentPhase I pharmacokinetic results showed the denifanstat–resmetirom combination was generally well tolerated with no safety signals or discontinuations, supporting advancement to a Phase 2 study in patients with advanced MASH.
Intellectual Property And PartnershipsA global license agreement with TAPI for an innovative resmetirom API reduces potential intellectual property obstacles and enables development of a co‑formulated fixed‑dose combination to support pivotal studies.