Clinical Trial ProgressPhase I pharmacokinetic and safety results showed the denifanstat and resmetirom combination was generally well tolerated with no serious adverse events or discontinuations, supporting advancement to a Phase 2 program in advanced liver fibrosis.
Pipeline Breadth And Commercial PotentialDevelopment of multiple FASN inhibitors across acne and liver disease, plus partner activity toward local approval in China, expands commercial pathways and increases upside if efficacy trials succeed.
Strategic Licensing And IPA global license agreement with TAPI for an innovative resmetirom API reduces intellectual property risk around the combo approach and enables work toward a fixed-dose co‑formulation for later‑stage development.