Efficacy And SafetyThe combination of ADG126 and pembrolizumab achieved an overall response rate of 33% in patients with no liver and peritoneal metastases, showing significant improvement over previous cohorts.
Regulatory ApprovalExperts believe a drug delivering high response rates, along with maintaining repeat dosing and durable efficacy, is likely to receive FDA approval, potentially through an Accelerated Approval pathway.
Therapeutic PotentialADG126 presented positive data from its ongoing Phase 1/2 study at the American Society of Clinical Oncology Gastrointestinal Cancers Symposium, solidifying its therapeutical potential in metastatic microsatellite stable colorectal cancer.