Clinical Promise Of INF904INF904 showed rapid, meaningful anti-inflammatory effects with a manageable safety profile in both chronic spontaneous urticaria and hidradenitis suppurativa, indicating potential for a single oral therapy addressing multiple inflammatory conditions.
Cost Reductions And Runway ExtensionCost reduction measures, workforce reductions, and cuts to vilobelimab commercial spending extend the company’s cash runway and free capital to focus on high-value clinical programs like izicopan.
Pipeline Prioritization For IzicopanDecision to prioritize izicopan and engage the FDA on Phase 2b trial design for hidradenitis suppurativa, along with plans for a pharmacokinetic bridging study in China, increases chances of efficient development and broader regional proof-of-concept.