Clinical TrialsAll remaining clinical studies involving masofaniten, including those combining it with abiraterone acetate and apalutamide and other investigator-sponsored trials, will be discontinued.
Drug DevelopmentEPIX announced that it will discontinue all masofaniten development following a pre-specified futility analysis that showed that this candidate failed to meet the target efficacy profile in the Phase 2 enzalutamide combo study in mCRPC patients naïve to second-generation antiandrogens.
Financial OutlookBased on projected YE25 cash of ~$105M, analyst is lowering the price target to $2 from $15.