Strong Financial Position
Revolution Medicines ended the fourth quarter of 2024 with $2.3 billion in cash and investments, including $823 million from an equity offering, projecting funding for operations into the second half of 2027.
Advancements in RAS(ON) Inhibitor Pipeline
Significant progress was made with RAS-focused drugs, reporting compelling monotherapy clinical data, especially with daraxonrasib in pancreatic ductal adenocarcinoma (PDAC) and non-small cell lung cancer.
Initiation of Phase III Trials
Commencement of Phase III trials for daraxonrasib in non-small cell lung cancer and PDAC, aiming for substantial enrollment completion in 2025.
Strategic Collaborations
Entered into discovery and clinical collaborations to expand treatment strategies, including a PRMT5 inhibitor with Tango and bispecific antibodies with Aethon Therapeutics.